Donald W. Nicholson

35.6k citations
141 papers · 28.3k · 13 hit papers · h-index 69

Impact in

    • Cell death mechanisms and regulation
    • Mitochondrial Function and Pathology
    • RNA Interference and Gene Delivery
  • Immunology top 0.2%
    • Phagocytosis and Immune Regulation

Papers in

    • Cell death mechanisms and regulation 61
    • Mitochondrial Function and Pathology 24
    • Ubiquitin and proteasome pathways 8
    • Phagocytosis and Immune Regulation 9

Donald W. Nicholson

140 papers receiving 27.5k citations

Donald W. Nicholson's Hit Papers

Apoptosis and caspases regulate death and inflammation in sepsis 2006 · 660 citations
6600+12+24Years since publication10002.0k3.0k

Peers

Donald W. Nicholson
Comparison fields: 5 of 153
  • Molecular Biology 20.4k
  • Immunology 5.2k
  • Cellular and Molecular Neuroscience 3.4k
  • Cell Biology 3.0k
  • Cancer Research 2.0k
Replace Nancy A. Thornberry with:
Nancy A. Thornberry United States
Yoshihide Tsujimoto Japan
Naoufal Zamzami France
Santos A. Susín France
Boris Zhivotovsky Sweden
A Currie United Kingdom
A H Wyllie United Kingdom
Hidenori Ichijo Japan
Hong‐Gang Wang United States
Jean‐Claude Martinou Switzerland
Donald W. Nicholson relative to Nancy A. Thornberry United States Nancy A. Thornberry's profile →
Citations per field
00.5×1.5×
Nancy A. Thornberry · 1×
Citations per year

Countries citing papers authored by Donald W. Nicholson

Since Specialization
Citations

This map shows the geographic impact of Donald W. Nicholson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Donald W. Nicholson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Donald W. Nicholson more than expected).

Fields of papers citing papers by Donald W. Nicholson

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Donald W. Nicholson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Donald W. Nicholson. The network helps show where Donald W. Nicholson may publish in the future.

Co-authors

The 25 scholars most cited alongside Donald W. Nicholson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Donald W. Nicholson Line = papers co-authored together Donald W. Nicholson links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 141 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
Hit paper breakdown →
19953686
2
Caspases: killer proteases
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19972152
3
A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B
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19971863
4
Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner
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19991693
5
Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors
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1998878
6
Mitochondrial protein import
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1989764
7
Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation
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1999703
8
Apoptosis and caspases regulate death and inflammation in sepsis
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2006660
9
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
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1995637
10
From bench to clinic with apoptosis-based therapeutic agents
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2000598
11
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.
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1996581
12
Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin
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2006534
13
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
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1996503
14 2000469
15 1996453
16 1996447
17 2002399
18 1998376
19 1996372
20 1999357

About Donald W. Nicholson

Donald W. Nicholson is a scholar working on Molecular Biology, Immunology, Cell Biology, Cellular and Molecular Neuroscience and Oncology, having authored 141 papers that have together received 28.3k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (61 papers), Mitochondrial Function and Pathology (24 papers), Autophagy in Disease and Therapy (10 papers), Asthma and respiratory diseases (10 papers), Endoplasmic Reticulum Stress and Disease (10 papers), Phagocytosis and Immune Regulation (9 papers), Genetic Neurodegenerative Diseases (9 papers) and Ubiquitin and proteasome pathways (8 papers). The work is most often cited by research in Molecular Biology (20.4k citations), Immunology (5.2k citations), Cellular and Molecular Neuroscience (3.4k citations), Cell Biology (3.0k citations) and Cancer Research (2.0k citations). Donald W. Nicholson has collaborated with scholars based in Canada, United States and Germany. Frequent co-authors include Nancy A. Thornberry, Sophie Roy, John P. Vaillancourt, Erin P. Peterson, Richard S. Hotchkiss, Douglas K. Miller, Dita Rasper, Margarita García‐Calvo, Ting-Ting Yamin and Walter Neupert. Their work appears in journals such as Journal of Biological Chemistry, Journal of Neuroscience, Bioorganic & Medicinal Chemistry Letters, Cell Death and Differentiation and Nature.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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