Douglas R. Green

956 total papers · 182.9k total citations
612 papers, 124.7k citations indexed

About

Douglas R. Green is a scholar working on Molecular Biology, Immunology and Epidemiology. According to data from OpenAlex, Douglas R. Green has authored 612 papers receiving a total of 124.7k indexed citations (citations by other indexed papers that have themselves been cited), including 371 papers in Molecular Biology, 254 papers in Immunology and 120 papers in Epidemiology. Recurrent topics in Douglas R. Green's work include Cell death mechanisms and regulation (267 papers), Autophagy in Disease and Therapy (99 papers) and Immune Cell Function and Interaction (86 papers). Douglas R. Green is often cited by papers focused on Cell death mechanisms and regulation (267 papers), Autophagy in Disease and Therapy (99 papers) and Immune Cell Function and Interaction (86 papers). Douglas R. Green collaborates with scholars based in United States, Canada and United Kingdom. Douglas R. Green's co-authors include John C. Reed, Guido Kroemer, Séamus J. Martin, Jerry E. Chipuk, Donald D. Newmeyer, Stephen W. G. Tait, Ella Bossy‐Wetzel, Ruth M. Kluck, Martin Schüler and Beni B. Wolf and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Douglas R. Green

608 papers receiving 122.7k citations

Hit Papers

Mitochondria and Apoptosis 1992 2026 2003 2014 1998 1997 2004 1995 1996 2.5k 5.0k 7.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation benchmark for papers published in the same subfield and year, or reaches the top citation threshold in at least one of its specific research topics.

  1. Mitochondria and Apoptosis
    1998 7.9k citations Douglas R. Green, John C. Reed Science profile →
  2. The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
    1997 4.1k citations Ruth M. Kluck, Ella Bossy‐Wetzel et al. Science profile →
  3. The Pathophysiology of Mitochondrial Cell Death
    2004 2.8k citations Douglas R. Green, Guido Kroemer Science profile →
  4. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.
    1995 2.5k citations Séamus J. Martin, Anne J. McGahon et al. The Journal of Experimental Medicine profile →
  5. Suppression of TNF-α-Induced Apoptosis by NF-κB
    1996 2.3k citations Séamus J. Martin, Douglas R. Green et al. Science profile →
  6. Mitochondria and cell death: outer membrane permeabilization and beyond
    2010 2.0k citations Stephen W. G. Tait, Douglas R. Green Nature Reviews Molecular Cell Biology profile →
  7. Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege
    1995 1.7k citations Thomas S. Griffith, Thomas Brunner et al. Science profile →
  8. Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
    2004 1.7k citations Jerry E. Chipuk, Tomomi Kuwana et al. Science profile →
  9. Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner
    1999 1.6k citations Ruth M. Kluck, Beni B. Wolf et al. The Journal of Cell Biology profile →
  10. The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
    2011 1.6k citations Ruoning Wang, Christopher P. Dillon et al. Immunity profile →
  11. HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
    2011 1.4k citations Lewis Z. Shi, Ruoning Wang et al. The Journal of Experimental Medicine profile →
  12. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
    2000 1.3k citations Helen M. Beere, Beni B. Wolf et al. Nature Cell Biology profile →
  13. The BCL-2 Family Reunion
    2010 1.2k citations Jerry E. Chipuk, Tudor Moldoveanu et al. Molecular Cell profile →
  14. Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane
    2002 1.2k citations Tomomi Kuwana, Mason Mackey et al. Cell profile →
  15. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    1995 1.2k citations Thomas Brunner, R J Mogil et al. Nature profile →
  16. Protease activation during apoptosis: Death by a thousand cuts?
    1995 1.2k citations Séamus J. Martin, Douglas R. Green Cell profile →
  17. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
    2007 1.1k citations Miguel A. F. Sanjuán, Christopher P. Dillon et al. Nature profile →
  18. Apoptotic Pathways
    1998 1.1k citations Douglas R. Green Cell profile →
  19. Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
    2011 993 citations Andrew Oberst, Christopher P. Dillon et al. Nature profile →
  20. A matter of life and death
    2002 967 citations Douglas R. Green, Gérard I. Evan Cancer Cell profile →
  21. Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
    2008 957 citations Jerry E. Chipuk, Elena Ingerman et al. Developmental Cell profile →
  22. BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly
    2005 952 citations Tomomi Kuwana, Lisa Bouchier‐Hayes et al. Molecular Cell profile →
  23. Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging
    2011 944 citations Douglas R. Green, Lorenzo Galluzzi et al. Science profile →
  24. Immunogenic and tolerogenic cell death
    2009 909 citations Douglas R. Green, T. Ferguson et al. Nature reviews. Immunology profile →
  25. Cytochrome c: functions beyond respiration
    2008 893 citations Douglas R. Green, Zhenyue Hao et al. Nature Reviews Molecular Cell Biology profile →
  26. Necroptosis
    2014 879 citations Andreas Linkermann, Douglas R. Green New England Journal of Medicine profile →
  27. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
    2000 879 citations Joshua C. Goldstein, Nigel J. Waterhouse et al. Nature Cell Biology profile →
  28. Cytoplasmic functions of the tumour suppressor p53
    2009 872 citations Douglas R. Green, Guido Kroemer Nature profile →
  29. Apoptotic Pathways
    2000 865 citations Douglas R. Green Cell profile →
  30. Cell Death Signaling
    2015 858 citations Douglas R. Green, Fabien Llambi Cold Spring Harbor Perspectives in Biology profile →
  31. Apoptotic cell death induced by c-myc is inhibited by bcl-2
    1992 841 citations Reid P. Bissonnette, Fernando Echeverri et al. Nature profile →
  32. Suicidal Tendencies: Apoptotic Cell Death by Caspase Family Proteinases
    1999 813 citations Beni B. Wolf, Douglas R. Green Journal of Biological Chemistry profile →
  33. Breaking the mitochondrial barrier
    2001 803 citations Jean‐Claude Martinou, Douglas R. Green Nature Reviews Molecular Cell Biology profile →
  34. c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
    2012 792 citations Zuqin Nie, Gangqing Hu et al. Cell profile →
  35. How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
    2008 784 citations Jerry E. Chipuk, Douglas R. Green Trends in Cell Biology profile →
  36. The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways
    2002 765 citations Emmanuel Dejardin, Nathalie Droin et al. Immunity profile →
  37. Necroptosis in development, inflammation and disease
    2016 750 citations Ricardo Weinlich, Andrew Oberst et al. Nature Reviews Molecular Cell Biology profile →
  38. Distinct Caspase Cascades Are Initiated in Receptor-mediated and Chemical-induced Apoptosis
    1999 748 citations Beni B. Wolf, Douglas R. Green et al. Journal of Biological Chemistry profile →
  39. A Unified Model for Apical Caspase Activation
    2003 739 citations Kelly M. Boatright, Martin Renatus et al. Molecular Cell profile →
  40. Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization and Apoptosis by Destabilization of MCL-1
    2006 704 citations Ulrich Maurer, Céline Charvet et al. Molecular Cell profile →
  41. Acid Sphingomyelinase–Deficient Human Lymphoblasts and Mice Are Defective in Radiation-Induced Apoptosis
    1996 689 citations M Santana, Louis A. Peña et al. Cell profile →
  42. Autophagy-Independent Functions of the Autophagy Machinery
    2019 676 citations Lorenzo Galluzzi, Douglas R. Green Cell profile →
  43. Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
    2018 671 citations Douglas R. Green et al. Proceedings of the National Academy of Sciences profile →
  44. The machinery of programmed cell death
    2001 669 citations Katja Zimmermann, Christine Bonzon et al. Pharmacology & Therapeutics profile →
  45. Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
    2017 667 citations Lorenzo Galluzzi, José Manuel Bravo‐San Pedro et al. Nature Reviews Drug Discovery profile →
  46. The central executioners of apoptosis: caspases or mitochondria?
    1998 663 citations Douglas R. Green, Guido Kroemer Trends in Cell Biology profile →
  47. Pro-caspase-3 Is a Major Physiologic Target of Caspase-8
    1998 649 citations Henning R. Stennicke, Juliane M. Jürgensmeier et al. Journal of Biological Chemistry profile →
  48. Apoptotic Pathways: Ten Minutes to Dead
    2005 641 citations Douglas R. Green Cell profile →
  49. Bax-induced Caspase Activation and Apoptosis via Cytochromec Release from Mitochondria Is Inhibitable by Bcl-xL
    1999 641 citations Deborah M. Finucane, Ella Bossy‐Wetzel et al. Journal of Biological Chemistry profile →
  50. DNA Damaging Agents Induce Expression of Fas Ligand and Subsequent Apoptosis in T Lymphocytes via the Activation of NF-κB and AP-1
    1998 627 citations Shailaja Kasibhatla, Thomas Brunner et al. Molecular Cell profile →
  51. Role for c-myc in Activation-Induced Apoptotic Cell Death in T Cell Hybridomas
    1992 618 citations Yufang Shi, Jacqueline M. Glynn et al. Science profile →
  52. Caspase‐8: regulating life and death
    2017 564 citations Bart Tummers, Douglas R. Green Immunological Reviews profile →
  53. To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
    2014 564 citations Douglas R. Green, Beth Levine Cell profile →
  54. The clearance of dead cells by efferocytosis
    2020 538 citations Emilio Boada-Romero, Jennifer Martinez et al. Nature Reviews Molecular Cell Biology profile →
  55. Chapter 9 The End of the (Cell) Line: Methods for the Study of Apoptosis in Vitro
    1995 518 citations Anne J. McGahon, Séamus J. Martin et al. Methods in cell biology profile →
  56. MOMP, cell suicide as a BCL-2 family business
    2017 504 citations Halime Kalkavan, Douglas R. Green Cell Death and Differentiation profile →
  57. Activation‐induced cell death in T cells
    2003 501 citations Douglas R. Green, Nathalie Droin et al. Immunological Reviews profile →
  58. Metabolic control of cell death
    2014 498 citations Douglas R. Green, Lorenzo Galluzzi et al. Science profile →
  59. Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease
    2016 496 citations Larissa D. Cunha, Ramnik J. Xavier et al. Science profile →
  60. RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8 + T cells
    2015 487 citations Nader Yatim, Susana Orozco et al. Science profile →
  61. ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
    2017 481 citations Yi‐Nan Gong, Cliff Guy et al. Cell profile →
  62. FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
    2014 464 citations Prajwal Gurung, Paras Anand et al. The Journal of Immunology profile →
  63. Autosis is a Na + ,K + -ATPase–regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia–ischemia
    2013 452 citations Rhea Sumpter, Douglas R. Green et al. Proceedings of the National Academy of Sciences profile →
  64. Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury
    2013 450 citations Andreas Linkermann, Jan Hinrich Bräsen et al. Proceedings of the National Academy of Sciences profile →
  65. Programmed necrosis in inflammation: Toward identification of the effector molecules
    2016 438 citations David Wallach, Tae‐Bong Kang et al. Science profile →
  66. The Coming Decade of Cell Death Research: Five Riddles
    2019 418 citations Douglas R. Green Cell profile →
  67. Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells
    2014 416 citations Alfredo Caro‐Maldonado, Ruoning Wang et al. The Journal of Immunology profile →
  68. LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease
    2019 382 citations Bradlee L. Heckmann, Brett J.W. Teubner et al. Cell profile →
  69. Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis
    2020 361 citations Ting Zhang, Chaoran Yin et al. Cell profile →
  70. Autophagy in tumour immunity and therapy
    2021 293 citations Houjun Xia, Douglas R. Green et al. Nature reviews. Cancer profile →
  71. Sublethal cytochrome c release generates drug-tolerant persister cells
    2022 132 citations Halime Kalkavan, Jinan Chen et al. Cell profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Douglas R. Green 80.8k 35.2k 18.8k 18.7k 15.1k 612 124.7k
John C. Reed 73.3k 0.9× 20.4k 0.6× 21.4k 1.1× 10.6k 0.6× 12.2k 0.8× 797 107.4k
Craig B. Thompson 91.7k 1.1× 36.6k 1.0× 25.3k 1.3× 16.0k 0.9× 44.5k 3.0× 515 150.8k
Tak W. Mak 49.5k 0.6× 33.9k 1.0× 22.6k 1.2× 7.3k 0.4× 17.0k 1.1× 710 95.8k
Vishva M. Dixit 62.3k 0.8× 32.9k 0.9× 13.0k 0.7× 9.2k 0.5× 15.7k 1.0× 315 87.9k
Roger J. Davis 62.4k 0.8× 13.6k 0.4× 15.6k 0.8× 7.5k 0.4× 11.6k 0.8× 570 92.5k
David Baltimore 76.3k 0.9× 46.6k 1.3× 18.2k 1.0× 11.4k 0.6× 32.5k 2.2× 804 141.6k
Richard A. Flavell 75.6k 0.9× 86.7k 2.5× 23.0k 1.2× 19.7k 1.0× 13.8k 0.9× 1.2k 178.7k
Lewis C. Cantley 104.9k 1.3× 16.8k 0.5× 27.4k 1.5× 8.7k 0.5× 29.7k 2.0× 708 150.1k
Shigekazu Nagata 42.4k 0.5× 32.9k 0.9× 10.8k 0.6× 7.8k 0.4× 6.7k 0.4× 615 76.4k
Matthias Mann 150.3k 1.9× 18.0k 0.5× 17.2k 0.9× 11.3k 0.6× 14.2k 0.9× 845 214.4k

Countries citing papers authored by Douglas R. Green

Since Specialization
Citations

This map shows the geographic impact of Douglas R. Green's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas R. Green with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas R. Green more than expected).

Fields of papers citing papers by Douglas R. Green

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas R. Green. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas R. Green. The network helps show where Douglas R. Green may publish in the future.

Co-authorship network of co-authors of Douglas R. Green

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas R. Green. A scholar is included among the top collaborators of Douglas R. Green based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas R. Green. Douglas R. Green is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

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Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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