Sten Orrenius

61.7k total citations · 15 hit papers
455 papers, 51.5k citations indexed

About

Sten Orrenius is a scholar working on Molecular Biology, Pharmacology and Biochemistry. According to data from OpenAlex, Sten Orrenius has authored 455 papers receiving a total of 51.5k indexed citations (citations by other indexed papers that have themselves been cited), including 253 papers in Molecular Biology, 81 papers in Pharmacology and 72 papers in Biochemistry. Recurrent topics in Sten Orrenius's work include Cell death mechanisms and regulation (125 papers), Pharmacogenetics and Drug Metabolism (60 papers) and Mitochondrial Function and Pathology (57 papers). Sten Orrenius is often cited by papers focused on Cell death mechanisms and regulation (125 papers), Pharmacogenetics and Drug Metabolism (60 papers) and Mitochondrial Function and Pathology (57 papers). Sten Orrenius collaborates with scholars based in Sweden, United States and Italy. Sten Orrenius's co-authors include Boris Zhivotovsky, Pierluigi Nicotera, Vladimir Gogvadze, David J. McConkey, Giorgio Bellomo, Hjördis Thor, Peter Moldéus, Pia Hartzell, Afshin Samali and Martin Ott and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Sten Orrenius

454 papers receiving 49.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Regulation of cell death: the calcium–apoptosis link

2003 2.4k citations Sten Orrenius, Boris Zhivotovsky et al. profile →
Mitochondria, oxidative stress and cell death

2007 1.6k citations Martin Ott, Vladimir Gogvadze et al. APOPTOSIS profile →
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1995 1.6k citations Boris Zhivotovsky, Sten Orrenius et al. profile →
Triggering and modulation of apoptosis by oxidative stress

2000 1.2k citations Joya Chandra, Sten Orrenius et al. profile →
[4] Isolation and use of liver cells

1978 1.1k citations Sten Orrenius et al. profile →
Mitochondrial Oxidative Stress: Implications for Cell Death

2006 1.1k citations Sten Orrenius, Vladimir Gogvadze et al. profile →
The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 808 citations Hjördis Thor, Giorgio Bellomo et al. Journal of Biological Chemistry profile →
Cytochrome c release from mitochondria proceeds by a two-step process

2002 783 citations Martin Ott, John D. Robertson et al. profile →
Role of Ca2+ in toxic cell killing

1989 733 citations Sten Orrenius, David J. McConkey et al. profile →
Mitochondria in cancer cells: what is so special about them?

2008 532 citations Vladimir Gogvadze, Sten Orrenius et al. profile →
Apoptosis: a basic biological phenomenon with wide‐ranging implications in human disease

2005 526 citations Bengt Fadeel, Sten Orrenius profile →
Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

1982 484 citations Giorgio Bellomo, Hjördis Thor et al. profile →
PHENOBARBITAL-INDUCED SYNTHESIS OF THE MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM AND ITS RELATIONSHIP TO THE PROLIFERATION OF ENDOPLASMIC MEMBRANES

1965 463 citations Sten Orrenius, Jan L. E. Ericsson et al. profile →
Calcium and mitochondria in the regulation of cell death

2015 421 citations Sten Orrenius, Vladimir Gogvadze et al. Biochemical and Biophysical Research Communications profile →
Fundamentals of drug metabolism and drug disposition

1973 396 citations Sten Orrenius et al. profile →

Peers

Countries citing papers authored by Sten Orrenius

Since Specialization

Citations

This map shows the geographic impact of Sten Orrenius's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sten Orrenius with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sten Orrenius more than expected).

Fields of papers citing papers by Sten Orrenius

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sten Orrenius. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sten Orrenius. The network helps show where Sten Orrenius may publish in the future.

Co-authorship network of co-authors of Sten Orrenius

This figure shows the co-authorship network connecting the top 25 collaborators of Sten Orrenius. A scholar is included among the top collaborators of Sten Orrenius based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sten Orrenius. Sten Orrenius is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Mitochondrial regulation of cell death: Processing of apoptosis-inducing factor (AIF) 2010 ·Biochemical and Biophysical Research Communications ·Erik Norberg, Sten Orrenius, Boris Zhivotovsky	215
2	Mitochondrial targeting of tBid/Bax: a role for the TOM complex? 2009 ·Cell Death and Differentiation ·Martin Ott, Erik Norberg, Boris Zhivotovsky, Sten Orrenius	79
3	Mitochondria, oxidative stress and cell death breakdown → 2007 ·APOPTOSIS ·Martin Ott, Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky	1630
4	Multiple pathways of cytochrome c release from mitochondria in apoptosis 2006 ·Biochimica et Biophysica Acta (BBA) - Bioenergetics ·Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky	384
5	Cardiolipin Is Not Required for Bax-mediated Cytochrome c Release from Yeast Mitochondria 2004 ·Journal of Biological Chemistry ·Suzanne L. Iverson, Mari Enoksson, Vladimir Gogvadze, Martin Ott, Sten Orrenius	65
6	Differential regulation of the mitochondrial and death receptor pathways in neural stem cells 2004 ·European Journal of Neuroscience ·Christoffer Tamm, John D. Robertson, (unknown), Mari Enoksson, Mia Emgård, Sten Orrenius, Sandra Ceccatelli	45
7	A Role for Oxidative Stress in Apoptosis: Oxidation and Externalization of Phosphatidylserine Is Required for Macrophage Clearance of Cells Undergoing Fas-Mediated Apoptosis 2002 ·The Journal of Immunology ·Valerian E. Kagan, (unknown), Yulia Y. Tyurina, Vladimir A. Tyurin, (unknown), (unknown), (unknown), Antonio Arroyo, Joya Chandra, Sten Orrenius, Bengt Fadeel	209
8	Adenosine Inhibits Protein Synthesis in Isolated Rat Hepatocytes 1995 ·European Journal of Biochemistry ·Sandrine A. Tinton, Sek C. Chow, Pedro Buc Calderón, George E.N. Kass, Sten Orrenius	14
9	Adenosine Inhibits Protein Synthesis in Isolated Rat Hepatocytes. Evidence for a Lack of Involvement of Intracellular Calcium in the Mechanism of Inhibition 1995 ·European Journal of Biochemistry ·Sandrine A. Tinton, Sek C. Chow, Pedro Buc Calderón, George E.N. Kass, Sten Orrenius	2
10	Isolation and partial characterization of a protease involved in Fas‐induced apoptosis 1995 ·FEBS Letters ·Jürgen Schlegel, (unknown), Sten Orrenius	37
11	Role of Nucleases in Apoptosis 1994 ·International Archives of Allergy and Immunology ·Boris Zhivotovsky, David Wade, Pierluigi Nicotera, Sten Orrenius	59
12	Genistein Induces Apoptosis in Immature Human Thymocytes by Inhibiting Topoisomerase-II 1993 ·Biochemical and Biophysical Research Communications ·Michael J. McCabe, Sten Orrenius	100
13	Cyclosporin a protects hepatocytes against prooxidant-induced cell killing 1992 ·Biochemical Pharmacology ·George E.N. Kass, Marlene J. Juedes, Sten Orrenius	83
14	m‐Iodobenzylguanidine increases the mitochondrial Ca²⁺ pool in isolated hepatocytes 1992 ·FEBS Letters ·Marlene J. Juedes, George E.N. Kass, Sten Orrenius	13
15	Rapid microfilament reorganization induced in isolated rat hepatocytes by microcystin-LR, a cyclic peptide toxin 1989 ·Experimental Cell Research ·John Eriksson, Gun I.L. Paatero, Jussi Meriluoto, G. A. Codd, (unknown), Pierluigi Nicotera, Sten Orrenius	123
16	Menadione-induced bleb formation in hepatocytes is associated with the oxidation of thiol groups in actin 1988 ·Archives of Biochemistry and Biophysics ·Francesca Mirabelli, Alberto Salis, (unknown), G Finardi, Giorgio Bellomo, Hjördis Thor, Sten Orrenius	143
17	2,5‐Di(tert‐butyl)‐1,4‐benzohydroquinone — a novel inhibitor of liver microsomal Ca²⁺ sequestration 1987 ·FEBS Letters ·Gregory Moore, David J. McConkey, Georges Kass, Peter J. O’Brien, Sten Orrenius	195
18	Effects of Oxidative Stress Caused by Hyperoxia and Diquat. A Study in Isolated Hepatocytes 1986 ·Free Radical Research Communications ·(unknown), Luisa Rossi, Hjördis Thor, Sten Orrenius	60
19	Fluorescence study of DNA-binding metabolites of benzo(a)pyrene formed in hepatocytes isolated from 3-methylcholanthrene-treated rats. 1978 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Bengt Jernström, Sten Orrenius, (unknown), Astrid Gräslund, Anders Ehrenberg	53
20	Effects of protein deficiency on hepatic parenchymal cells. Electron microscopic observations. 1966 ·Jan L. E. Ericsson, Sten Orrenius, Ingemar Holm	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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