Crystal N. Doty

2.7k total citations · 1 hit paper
18 papers, 1.9k citations indexed

About

Crystal N. Doty is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Neurology. According to data from OpenAlex, Crystal N. Doty has authored 18 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 18 papers in Cellular and Molecular Neuroscience and 2 papers in Neurology. Recurrent topics in Crystal N. Doty's work include Genetic Neurodegenerative Diseases (18 papers), Mitochondrial Function and Pathology (13 papers) and Muscle Physiology and Disorders (9 papers). Crystal N. Doty is often cited by papers focused on Genetic Neurodegenerative Diseases (18 papers), Mitochondrial Function and Pathology (13 papers) and Muscle Physiology and Disorders (9 papers). Crystal N. Doty collaborates with scholars based in Canada, United States and Netherlands. Crystal N. Doty's co-authors include Michael R. Hayden, Simon C. Warby, Amber L. Southwell, Niels H. Skotte, Jeffrey B. Carroll, Rona K. Graham, C. Frank Bennett, Jennifer A. Collins, Lynn A. Raymond and Susan M. Freier and has published in prestigious journals such as Cell, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Crystal N. Doty

18 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

2006 505 citations Rona K. Graham, Yu Deng et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Crystal N. Doty Canada	17	1.6k	1.4k	445	130	115	18	1.9k
Niels H. Skotte Denmark	19	1.3k 0.8×	852 0.6×	269 0.6×	134 1.0×	60 0.5×	30	1.6k
Maria do Carmo Costa United States	22	1.1k 0.6×	988 0.7×	298 0.7×	61 0.5×	76 0.7×	37	1.3k
Sharan Paul United States	19	1.0k 0.6×	688 0.5×	220 0.5×	104 0.8×	76 0.7×	37	1.2k
Nicholas S. Caron Canada	22	1.1k 0.7×	956 0.7×	353 0.8×	45 0.3×	130 1.1×	38	1.5k
Warunee Dansithong United States	19	1.0k 0.6×	732 0.5×	218 0.5×	111 0.9×	48 0.4×	35	1.2k
Tammy Gillis United States	22	1.5k 0.9×	1.3k 1.0×	506 1.1×	37 0.3×	147 1.3×	36	1.9k
Jillian K. Cooper United States	10	2.2k 1.3×	2.0k 1.5×	676 1.5×	58 0.4×	161 1.4×	16	2.5k
Peter J. Detloff United States	22	2.1k 1.3×	1.5k 1.1×	520 1.2×	61 0.5×	186 1.6×	41	2.5k
Francesca Persichetti Italy	28	2.1k 1.3×	1.7k 1.3×	735 1.7×	38 0.3×	207 1.8×	51	2.6k
Rahul Kanadia United States	16	1.7k 1.0×	1.0k 0.7×	162 0.4×	130 1.0×	81 0.7×	35	1.9k

Countries citing papers authored by Crystal N. Doty

Since Specialization

Citations

This map shows the geographic impact of Crystal N. Doty's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Crystal N. Doty with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Crystal N. Doty more than expected).

Fields of papers citing papers by Crystal N. Doty

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Crystal N. Doty. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Crystal N. Doty. The network helps show where Crystal N. Doty may publish in the future.

Co-authorship network of co-authors of Crystal N. Doty

This figure shows the co-authorship network connecting the top 25 collaborators of Crystal N. Doty. A scholar is included among the top collaborators of Crystal N. Doty based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Crystal N. Doty. Crystal N. Doty is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Caron, Nicholas S., et al.. (2021). Reliable Resolution of Full-Length Huntingtin Alleles by Quantitative Immunoblotting. Journal of Huntington s Disease. 10(3). 355–365. 7 indexed citations

Southwell, Amber L., Holly Kordasiewicz, Douglas R. Langbehn, et al.. (2018). Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease. Science Translational Medicine. 10(461). 89 indexed citations

Kay, Chris, Jennifer A. Collins, Niels H. Skotte, et al.. (2015). Huntingtin Haplotypes Provide Prioritized Target Panels for Allele-specific Silencing in Huntington Disease Patients of European Ancestry. Molecular Therapy. 23(11). 1759–1771. 64 indexed citations

Mattis, Virginia B., Colton M. Tom, Sergey Akimov, et al.. (2015). HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Human Molecular Genetics. 24(11). 3257–3271. 84 indexed citations

Skotte, Niels H., Amber L. Southwell, Michael E. Østergaard, et al.. (2014). Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients. PLoS ONE. 9(9). e107434–e107434. 85 indexed citations

Southwell, Amber L., Niels H. Skotte, Holly Kordasiewicz, et al.. (2014). In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides. Molecular Therapy. 22(12). 2093–2106. 107 indexed citations

Semaka, Alicia, et al.. (2013). High frequency of intermediate alleles on huntington disease‐associated haplotypes in British Columbia's general population. American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 162(8). 864–871. 34 indexed citations

Kay, Chris, Maria E. Ketelaar, Jennifer A. Collins, et al.. (2013). Huntington disease in the South African population occurs on diverse and ethnically distinct genetic haplotypes. European Journal of Human Genetics. 21(10). 1120–1127. 46 indexed citations

Parsons, Matthew P., Rujun Kang, Amber L. Southwell, et al.. (2013). Bidirectional Control of Postsynaptic Density-95 (PSD-95) Clustering by Huntingtin. Journal of Biological Chemistry. 289(6). 3518–3528. 32 indexed citations

10.

Østergaard, Michael E., Amber L. Southwell, Holly Kordasiewicz, et al.. (2013). Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS. Nucleic Acids Research. 41(21). 9634–9650. 122 indexed citations

11.

Semaka, Alicia, Chris Kay, Crystal N. Doty, et al.. (2013). CAG size-specific risk estimates for intermediate allele repeat instability in Huntington disease. Journal of Medical Genetics. 50(10). 696–703. 55 indexed citations

12.

Sutton, Liza M., Shaun S. Sanders, Stefanie Butland, et al.. (2012). Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease. Human Molecular Genetics. 22(3). 452–465. 59 indexed citations

13.

Southwell, Amber L., Simon C. Warby, Jeffrey B. Carroll, et al.. (2012). A fully humanized transgenic mouse model of Huntington disease. Human Molecular Genetics. 22(1). 18–34. 69 indexed citations

14.

Carroll, Jeffrey B., Simon C. Warby, Amber L. Southwell, et al.. (2011). Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin. Molecular Therapy. 19(12). 2178–2185. 225 indexed citations

15.

Warby, Simon C., Henk Visscher, Jennifer A. Collins, et al.. (2011). HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia. European Journal of Human Genetics. 19(5). 561–566. 120 indexed citations

16.

Warby, Simon C., Crystal N. Doty, Rona K. Graham, et al.. (2008). Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus. Human Molecular Genetics. 17(15). 2390–2404. 106 indexed citations

17.

Warby, Simon C., et al.. (2008). Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments. Molecular and Cellular Neuroscience. 40(2). 121–127. 72 indexed citations

18.

Graham, Rona K., Yu Deng, Elizabeth Slow, et al.. (2006). Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin. Cell. 125(6). 1179–1191. 505 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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