Thomas A. Rano

2.9k citations

15 papers · 2.4k indexed · 1 hit paper · h-index 12

Impact in

Molecular Biology top 5%
- Cell death mechanisms and regulation
- Chemical Synthesis and Analysis
- RNA Interference and Gene Delivery
- Mitochondrial Function and Pathology
Immunology top 10%
- interferon and immune responses
- Phagocytosis and Immune Regulation

Papers in

Virology 3
- HIV Research and Treatment 3
Hepatology 2
- Hepatitis C virus research 2

Co-authors: Kevin T. Chapman Nancy A. Thornberry Erin P. Peterson Donald W. Nicholson Dita Rasper Margarita García‐Calvo Sophie Roy John P. Vaillancourt
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Tetrahedron Letters (2 papers)JACC Heart Failure (1 paper)Journal of the American Chemical Society (1 paper)Organic Letters (1 paper)
Partner nations: United States Austria Italy

In The Last Decade

Thomas A. Rano

15 papers receiving 2.3k citations

Hit Papers

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A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B 1997 · 1.8k citations

Peers

Countries citing papers authored by Thomas A. Rano

Since Specialization

Citations

This map shows the geographic impact of Thomas A. Rano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas A. Rano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas A. Rano more than expected).

Fields of papers citing papers by Thomas A. Rano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas A. Rano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas A. Rano. The network helps show where Thomas A. Rano may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Thomas A. Rano, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas A. Rano Line = papers co-authored together Thomas A. Rano links everyone, so they are left out of the graph.

All Works

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15 of 15 papers shown

#	Work
1	Mavacamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy JACC Heart Failure ·Milind Y. Desai, S.E. Nissen, Theodore P. Abraham, Iacopo Olivotto, Pablo García‐Pavía, (unknown), Nicolas Verheyen, Omar Wever‐Pinzon, Mischele Alejandra, Wael A. Jaber, कैलाश कुमार Kailash Kumar राई, Deborah Davey, Jonathan Myers, Thomas A. Rano, Charles Zumbrunnen, Н. В. Иванова, Chokri Massoudi, Victoria Florea, Francisco Emílio Surian, Anjali Owens	2025	11
2	4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: Part 2. Pyridazine-based analogs Bioorganic & Medicinal Chemistry Letters ·Shyh‐Ming Yang, Yuting Tang, Thomas A. Rano, Erin Elizabeth Marie Sweeney, Gee‐Hong Kuo, Michael D. Gaul, Yaxin Li, Elmer Jay Brown, Wensheng Lang, James G. Conway, Yin Liang, James M. Lenhard, Keith T. Demarest, William V. Murray	2014	6
3	Design and synthesis of potent inhibitors of cholesteryl ester transfer protein (CETP) exploiting a 1,2,3,4-tetrahydroquinoline platform Bioorganic & Medicinal Chemistry Letters ·Thomas A. Rano, Ellen Sieber-McMaster, Patricia D. Pelton, Maria Yang, Keith T. Demarest, Gee‐Hong Kuo	2009	77
4	Design, Synthesis, and Biological Evaluation of (2R,αS)-3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-α-(trifluoromethyl)-1(2H)-quinolineethanol as Potent and Orally Active Cholesteryl Ester Transfer Protein Inhibitor Journal of Medicinal Chemistry ·Gee‐Hong Kuo, Thomas A. Rano, Patricia D. Pelton, Keith T. Demarest, Alan C. Gibbs, William V. Murray, Bruce P. Damiano, Margery A. Connelly	2009	34
5	Improved Asymmetric Synthesis of 3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-α-(trifluoromethyl)-1(2H)-quinolineethanol, a Potent Cholesteryl Ester Transfer Protein Inhibitor Organic Letters ·Thomas A. Rano, Gee‐Hong Kuo	2009	22
6	HIV protease inhibitors with picomolar potency against PI-Resistant HIV-1 by extension of the P3 substituent Bioorganic & Medicinal Chemistry Letters ·Joseph Duffy, Thomas A. Rano, Maclean Mwamlangala, Kevin T. Chapman, William A. Schleif, David B. Olsen, Mark W. Stahlhut, Carrie A. Rutkowski, Lawrence C. Kuo, Lixia Jin, Jiunn H. Lin, Emilio A. Emini, James R. Tata	2003	15
7	Indinavir analogues with blocked metabolism sites as HIV protease inhibitors with improved pharmacological profiles and high potency against PI-Resistant viral strains Bioorganic & Medicinal Chemistry Letters ·Yuan Cheng, Fengqi Zhang, Thomas A. Rano, Zhijian Lu, William A. Schleif, Lori J. Gabryelski, David B. Olsen, Mark W. Stahlhut, Carrie A. Rutkowski, Jiunn H. Lin, Lixia Jin, Emilio A. Emini, Kevin T. Chapman, James R. Tata	2002	23
8	A Combinatorial Library of Indinavir Analogues and Its In Vitro and In Vivo Studies Bioorganic & Medicinal Chemistry Letters ·Yuan Cheng, Thomas A. Rano, Mauro Procknor, Fengqi Zhang, Zhijian Lu, William A. Schleif, Lori J. Gabryelski, David B. Olsen, Mark W. Stahlhut, Lawrence C. Kuo, Jiunn H. Lin, Xin Xu, Lixia Jin, Timothy Olah, Debra A. McLoughlin, Lizze Cain, Kevin T. Chapman, James R. Tata	2002	6
9	Combinatorial diversification of indinavir: in vivo mixture dosing of an HIV protease inhibitor library Bioorganic & Medicinal Chemistry Letters ·Thomas A. Rano, Yuan Cheng, Mauro Procknor, Fengqi Zhang, William A. Schleif, Lori J. Gabryelski, David B. Olsen, Lawrence C. Kuo, Jiunn H. Lin, Xin Xu, Timothy Olah, Debra A. McLoughlin, Richard C. King, Kevin T. Chapman, James R. Tata	2000	15
10	A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B Journal of Biological Chemistry ·Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson, Dita Rasper, Ana Laura Ávila, Margarita García‐Calvo, Claudia Klein, Sanaa Edrees, Sophie Roy, John P. Vaillancourt, Kevin T. Chapman, Donald W. Nicholson Hit paper breakdown →	1997	1802
11	A combinatorial approach for determining protease specificities: application to interleukin-1β converting enzyme (ICE) Chemistry & Biology ·Thomas A. Rano, Ana Laura Ávila, Erin P. Peterson, J. Rotonda, Donald W. Nicholson, Joseph W. Becker, Kevin T. Chapman, Nancy A. Thornberry	1997	216
12	Solid phase synthesis of aryl ethers via the mitsunobu reaction Tetrahedron Letters ·Thomas A. Rano, Kevin T. Chapman	1995	80
13	Total synthesis of the cytotoxic macrocycle (+)-hitachimycin Journal of the American Chemical Society ·Amos B. Smith, Thomas A. Rano, Noritaka Chida, Gary A. Sulikowski, John L. Wood	1992	44
14	Total synthesis of (+)-hitachimycin The Journal of Organic Chemistry ·Amos B. Smith, Thomas A. Rano, Noritaka Chida, Gary A. Sulikowski	1990	14
15	A highly efficient method for the preparation of 2-aryl substituted carbapenems exploiting a Pd(0) mediated cross-coupling reaction Tetrahedron Letters ·Thomas A. Rano, Mark L. Greenlee, Frank DiNinno	1990	33

About Thomas A. Rano

Thomas A. Rano is a scholar working on Virology, Hepatology, Infectious Diseases, Pharmacology and Organic Chemistry, having authored 15 papers that have together received 2.4k indexed citations. Recurring topics across this work include Synthetic Organic Chemistry Methods (4 papers), HIV/AIDS drug development and treatment (4 papers), Chemical Synthesis and Analysis (3 papers), HIV Research and Treatment (3 papers), Microbial Natural Products and Biosynthesis (3 papers), Computational Drug Discovery Methods (2 papers), Cholesterol and Lipid Metabolism (2 papers) and Hepatitis C virus research (2 papers). The work is most often cited by research in Molecular Biology (1.8k citations), Immunology (419 citations), Cell Biology (235 citations), Cancer Research (212 citations) and Oncology (365 citations). Thomas A. Rano has collaborated with scholars based in United States, Austria and Italy. Frequent co-authors include Kevin T. Chapman, Nancy A. Thornberry, Erin P. Peterson, Donald W. Nicholson, Dita Rasper, Margarita García‐Calvo, Sophie Roy, John P. Vaillancourt, Gee‐Hong Kuo and J. Rotonda. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Tetrahedron Letters, JACC Heart Failure, Journal of the American Chemical Society and Organic Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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