Yuri Lazebnik

23.3k total citations · 7 hit papers
53 papers, 19.3k citations indexed

About

Yuri Lazebnik is a scholar working on Molecular Biology, Oncology and Epidemiology. According to data from OpenAlex, Yuri Lazebnik has authored 53 papers receiving a total of 19.3k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Molecular Biology, 13 papers in Oncology and 8 papers in Epidemiology. Recurrent topics in Yuri Lazebnik's work include Cell death mechanisms and regulation (29 papers), RNA Interference and Gene Delivery (10 papers) and PARP inhibition in cancer therapy (6 papers). Yuri Lazebnik is often cited by papers focused on Cell death mechanisms and regulation (29 papers), RNA Interference and Gene Delivery (10 papers) and PARP inhibition in cancer therapy (6 papers). Yuri Lazebnik collaborates with scholars based in United States, Canada and United Kingdom. Yuri Lazebnik's co-authors include Nancy A. Thornberry, William C. Earnshaw, Scott H. Kaufmann, Guy G. Poirier, Serge Desnoyers, Joe Rodriguez, Ximena Opitz-Araya, Donald W. Nicholson, Marc Labelle and Michel Gallant and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Yuri Lazebnik

50 papers receiving 18.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Caspases: Enemies Within

1998 5.9k citations Yuri Lazebnik et al. profile →
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1995 3.6k citations Yuri Lazebnik et al. Nature profile →
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1994 2.3k citations Yuri Lazebnik, Scott H. Kaufmann et al. Nature profile →
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

2001 769 citations Marı́a S. Soengas, Paola Capodieci et al. Nature profile →
Requirement for Caspase-2 in Stress-Induced Apoptosis Before Mitochondrial Permeabilization

2002 596 citations Ximena Opitz-Araya, Yuri Lazebnik et al. profile →
Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction

2002 565 citations R.P. Hegde, Srinivasa M. Srinivasula et al. Journal of Biological Chemistry profile →
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells

2007 560 citations Yuri Lazebnik et al. The Journal of Cell Biology profile →

Peers

Countries citing papers authored by Yuri Lazebnik

Since Specialization

Citations

This map shows the geographic impact of Yuri Lazebnik's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yuri Lazebnik with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yuri Lazebnik more than expected).

Fields of papers citing papers by Yuri Lazebnik

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yuri Lazebnik. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yuri Lazebnik. The network helps show where Yuri Lazebnik may publish in the future.

Co-authorship network of co-authors of Yuri Lazebnik

This figure shows the co-authorship network connecting the top 25 collaborators of Yuri Lazebnik. A scholar is included among the top collaborators of Yuri Lazebnik based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yuri Lazebnik. Yuri Lazebnik is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Adopted neoplastic cells and the consequences of their existence 2023 ·Oncotarget ·Yuri Lazebnik	1
2	Cell Fusion as a Link between the SARS-CoV-2 Spike Protein, COVID-19 Complications, and Vaccine Side Effects 2021 ·Preprints.org ·Yuri Lazebnik	1
3	Are scientists a workforce? – Or, how Dr. Frankenstein made biomedical research sick 2015 ·EMBO Reports ·Yuri Lazebnik	5
4	The R-Factor: A Measure of Scientific Veracity 2014 ·Joshua M. Nicholson, Yuri Lazebnik	1
5	The Problem of Colliding Networks and its Relation to Cell Fusion and Cancer 2012 ·Biophysical Journal ·Alexei A. Koulakov, Yuri Lazebnik	12
6	What are the hallmarks of cancer? 2010 ·Nature reviews. Cancer ·Yuri Lazebnik	140
7	A Virus Causes Cancer by Inducing Massive Chromosomal Instability through Cell Fusion 2007 ·Current Biology ·Dominik M. Duelli, Hesed Padilla‐Nash, David M. Berman, Kathleen M. Murphy, Thomas Ried, Yuri Lazebnik	121
8	Cell-to-cell fusion as a link between viruses and cancer 2007 ·Nature reviews. Cancer ·Dominik M. Duelli, Yuri Lazebnik	159
9	Can a biologist fix a radio? — or, what I learned while studying apoptosis 2004 ·Biochemistry (Moscow) ·Yuri Lazebnik	21
10	The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells 2004 ·The Journal of Cell Biology ·Loretta Dorstyn, Kathryn Mills, Yuri Lazebnik, Sharad Kumar	100
11	Expression and transcriptional regulation of caspase-14 in simple and complex epithelia 2002 ·Cell Death and Differentiation ·Giuseppa Pistritto, (unknown), Srinivasa M. Srinivasula, Raffaele Baffa, Jean‐Luc Poyet, Csaba Kari, Yuri Lazebnik, Ulrich Rodeck, Emad S. Alnemri	46
12	Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction breakdown → 2002 ·Journal of Biological Chemistry ·R.P. Hegde, Srinivasa M. Srinivasula, Zhijia Zhang, Richard Wassell, (unknown), Lucia Cilenti, G C Dubois, Yuri Lazebnik, Antonis S. Zervos, Teresa Fernandes‐Alnemri, Emad S. Alnemri	565
13	Inactivation of the apoptosis effector Apaf-1 in malignant melanoma breakdown → 2001 ·Nature ·Marı́a S. Soengas, Paola Capodieci, David Polsky, Jaume Mora, Manel Esteller, Ximena Opitz-Araya, W. Richard McCombie, James G. Herman, William L. Gerald, Yuri Lazebnik, Carlos Cordon‐Cardo, Scott W. Lowe	769
14	Why do regulators of apoptosis look like bacterial toxins? 2001 ·Current Biology ·Yuri Lazebnik	23
15	Primary cells suppress oncogene-dependent apoptosis 2000 ·Nature Cell Biology ·Dominik M. Duelli, Yuri Lazebnik	48
16	Caspases Disrupt the Nuclear-Cytoplasmic Barrier 2000 ·The Journal of Cell Biology ·(unknown), Yuri Lazebnik	214
17	Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia 2000 ·Blood ·Phyllis A. Svingen, Judith E. Karp, Stan Krajewski, Peter W. Mesner, Steven D. Gore, Philip J. Burke, John C. Reed, Yuri Lazebnik, Scott H. Kaufmann	44
18	Caspase-3-dependent Cleavage of Bcl-2 Promotes Release of Cytochrome c 1999 ·Journal of Biological Chemistry ·David G. Kirsch, Andrea I. Doseff, B. Nelson Chau, Dae‐Sik Lim, Nadja C. de Souza‐Pinto, Richard G. Hansford, Michael B. Kastan, Yuri Lazebnik, J. Marie Hardwick	414
19	Crystal structure of apaf-1 caspase recruitment domain: an α-helical greek key fold for apoptotic signaling 1 1Edited by D. C. Rees 1999 ·Journal of Molecular Biology ·Daniel E. Vaughn, Joe Rodriguez, Yuri Lazebnik, Leemor Joshua‐Tor	67
20	Caspase-9 and APAF-1 form an active holoenzyme 1999 ·Genes & Development ·Joe Rodriguez, Yuri Lazebnik	443

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact