Jürg Tschopp

108.8k total citations · 39 hit papers
283 papers, 87.3k citations indexed

About

Jürg Tschopp is a scholar working on Immunology, Molecular Biology and Cancer Research. According to data from OpenAlex, Jürg Tschopp has authored 283 papers receiving a total of 87.3k indexed citations (citations by other indexed papers that have themselves been cited), including 176 papers in Immunology, 171 papers in Molecular Biology and 43 papers in Cancer Research. Recurrent topics in Jürg Tschopp's work include Inflammasome and immune disorders (85 papers), Immune Response and Inflammation (65 papers) and Cell death mechanisms and regulation (48 papers). Jürg Tschopp is often cited by papers focused on Inflammasome and immune disorders (85 papers), Immune Response and Inflammation (65 papers) and Cell death mechanisms and regulation (48 papers). Jürg Tschopp collaborates with scholars based in Switzerland, United States and Germany. Jürg Tschopp's co-authors include Fabio Martinon, Kate Schroder, Kimberly Burns, Virginie Pétrilli, Rongbin Zhou, Aubry Tardivel, Pascal Schneider, Olivier Micheau, Amir S. Yazdi and Etienne Meylan and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Jürg Tschopp

283 papers receiving 85.8k citations

Hit Papers

The Inflammasome 1994 2026 2004 2015 2002 2010 2010 2006 2009 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Inflammasome
    2002 4.8k citations Fabio Martinon, Jürg Tschopp et al. Molecular Cell profile →
  2. The Inflammasomes
    2010 4.5k citations Jürg Tschopp et al. profile →
  3. A role for mitochondria in NLRP3 inflammasome activation
    2010 4.4k citations Rongbin Zhou, Amir S. Yazdi et al. Nature profile →
  4. Gout-associated uric acid crystals activate the NALP3 inflammasome
    2006 4.1k citations Fabio Martinon, Virginie Pétrilli et al. Nature profile →
  5. Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    2009 2.2k citations Rongbin Zhou, Aubry Tardivel et al. profile →
  6. Inhibition of death receptor signals by cellular FLIP
    1997 2.1k citations Pascal Schneider, Kay Hofmann et al. Nature profile →
  7. Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
    2008 2.1k citations Catherine Dostert, Virginie Pétrilli et al. Science profile →
  8. Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
    2003 2.1k citations Jürg Tschopp et al. profile →
  9. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
    2005 2.0k citations Etienne Meylan, Joseph Curran et al. Nature profile →
  10. The Inflammasomes: Guardians of the Body
    2009 1.9k citations Fabio Martinon, Jürg Tschopp et al. profile →
  11. Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
    2000 1.5k citations Pascal Schneider, Jürg Tschopp et al. profile →
  12. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
    2010 1.5k citations Jürg Tschopp et al. profile →
  13. NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder
    2004 1.4k citations Fabio Martinon, Jürg Tschopp et al. profile →
  14. Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations
    1999 1.2k citations Fabienne Mackay, Pascal Schneider et al. The Journal of Experimental Medicine profile →
  15. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
    2007 1.2k citations Virginie Pétrilli, Catherine Dostert et al. Cell Death and Differentiation profile →
  16. BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth
    1999 1.1k citations Pascal Schneider, Fabienne Mackay et al. The Journal of Experimental Medicine profile →
  17. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
    1997 1.1k citations Pascal Schneider, Kay Hofmann et al. Nature profile →
  18. The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
    2010 924 citations Rongbin Zhou, Jürg Tschopp et al. Science profile →
  19. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
    1994 920 citations Jürg Tschopp et al. Nature profile →
  20. Intracellular pattern recognition receptors in the host response
    2006 916 citations Etienne Meylan, Jürg Tschopp et al. Nature profile →
  21. BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF
    2001 751 citations Teresa G. Cachero, Pascal Schneider et al. Science profile →
  22. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
    2008 750 citations Virginie Pétrilli, Jürg Tschopp et al. Nature profile →
  23. Inflammatory Caspases
    2004 750 citations Fabio Martinon, Jürg Tschopp profile →
  24. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
    2009 742 citations Olaf Groß, Catherine Dostert et al. Nature profile →
  25. Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
    2011 731 citations Aubry Tardivel, Jürg Tschopp et al. profile →
  26. The molecular architecture of the TNF superfamily
    2002 706 citations Pascal Schneider, Jürg Tschopp et al. profile →
  27. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome
    2002 681 citations Joanna R. Groom, Susan L. Kalled et al. Journal of Clinical Investigation profile →
  28. RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation
    2004 674 citations Etienne Meylan, Kay Hofmann et al. profile →
  29. Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
    2011 664 citations Jürg Tschopp et al. profile →
  30. The inflammasome: an integrated view
    2011 651 citations Olaf Groß, Jürg Tschopp et al. profile →
  31. Inflammatory caspases and inflammasomes: master switches of inflammation
    2006 645 citations Fabio Martinon, Jürg Tschopp Cell Death and Differentiation profile →
  32. TRAIL Receptors 1 (DR4) and 2 (DR5) Signal FADD-Dependent Apoptosis and Activate NF-κB
    1997 605 citations Pascal Schneider, Kay Hofmann et al. profile →
  33. Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation
    2013 605 citations Aubry Tardivel, Rosa Castillo et al. profile →
  34. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome
    2002 601 citations Joanna R. Groom, Susan L. Kalled et al. Journal of Clinical Investigation profile →
  35. Baff Mediates Survival of Peripheral Immature B Lymphocytes
    2000 579 citations Marcel Batten, Joanna R. Groom et al. The Journal of Experimental Medicine profile →
  36. NALPs: a novel protein family involved in inflammation
    2003 578 citations Jürg Tschopp, Fabio Martinon et al. profile →
  37. The inflammasome: a danger sensing complex triggering innate immunity
    2007 564 citations Virginie Pétrilli, Catherine Dostert et al. profile →
  38. A pilot study of IL-1 inhibition by anakinra in acute gout
    2007 562 citations Alexander So, Thibaut De Smedt et al. profile →
  39. MyD88, an Adapter Protein Involved in Interleukin-1 Signaling
    1998 532 citations Fabio Martinon, Pascal Schneider et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jürg Tschopp Switzerland 131 52.0k 43.3k 11.9k 8.1k 7.7k 283 87.3k
Charles A. Dinarello United States 174 36.8k 0.7× 47.0k 1.1× 15.9k 1.3× 5.5k 0.7× 11.9k 1.5× 873 108.0k
Gabriel Núñez United States 131 46.9k 0.9× 33.2k 0.8× 10.6k 0.9× 6.3k 0.8× 8.9k 1.2× 383 82.2k
Katherine A. Fitzgerald United States 119 37.7k 0.7× 39.7k 0.9× 12.3k 1.0× 6.9k 0.9× 5.2k 0.7× 334 69.4k
Vishva M. Dixit United States 141 62.4k 1.2× 32.9k 0.8× 9.2k 0.8× 15.7k 2.0× 13.0k 1.7× 315 88.1k
Eicke Latz Germany 101 32.3k 0.6× 31.6k 0.7× 8.9k 0.8× 3.7k 0.5× 2.9k 0.4× 283 61.2k
Anthony Cerami United States 135 18.8k 0.4× 20.7k 0.5× 10.8k 0.9× 3.6k 0.4× 6.5k 0.8× 514 76.7k
Richard A. Flavell United States 219 75.7k 1.5× 86.8k 2.0× 19.7k 1.7× 13.8k 1.7× 23.1k 3.0× 1.2k 179.2k
Kiyoshi Takeda Japan 118 27.9k 0.5× 57.1k 1.3× 14.7k 1.2× 10.5k 1.3× 9.7k 1.3× 463 92.8k
Shigekazu Nagata Japan 119 42.4k 0.8× 32.9k 0.8× 7.8k 0.7× 6.6k 0.8× 10.8k 1.4× 615 76.5k
Russell Ross United States 110 25.1k 0.5× 17.6k 0.4× 9.9k 0.8× 9.0k 1.1× 5.7k 0.7× 245 79.4k

Countries citing papers authored by Jürg Tschopp

Since Specialization
Citations

This map shows the geographic impact of Jürg Tschopp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jürg Tschopp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jürg Tschopp more than expected).

Fields of papers citing papers by Jürg Tschopp

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jürg Tschopp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jürg Tschopp. The network helps show where Jürg Tschopp may publish in the future.

Co-authorship network of co-authors of Jürg Tschopp

This figure shows the co-authorship network connecting the top 25 collaborators of Jürg Tschopp. A scholar is included among the top collaborators of Jürg Tschopp based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jürg Tschopp. Jürg Tschopp is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chow, Melvyn T., Jaclyn Sceneay, Christophe Paget, et al.. (2012). NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases. Cancer Research. 72(22). 5721–5732. 155 indexed citations
2.
Ritter, Manuel, Olaf Groß, Jürgen Ruland, et al.. (2010). Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proceedings of the National Academy of Sciences. 107(47). 20459–20464. 190 indexed citations
3.
Zhou, Rongbin, Amir S. Yazdi, Philippe Menu, & Jürg Tschopp. (2010). A role for mitochondria in NLRP3 inflammasome activation. Nature. 469(7329). 221–225. 4437 indexed citations breakdown →
4.
Gasse, Paméla, Nicolas Riteau, Sabine Charron, et al.. (2009). Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis. American Journal of Respiratory and Critical Care Medicine. 179(10). 903–913. 346 indexed citations
5.
Kolly, Laeticia, Leo A. B. Joosten, Sharmal Narayan, et al.. (2009). Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF. The Journal of Immunology. 183(6). 4003–4012. 67 indexed citations
6.
Dostert, Catherine, Virginie Pétrilli, Robin van Bruggen, et al.. (2008). Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica. Science. 320(5876). 674–677. 2113 indexed citations breakdown →
7.
Rebsamen, Manuele, Etienne Meylan, Joseph Curran, & Jürg Tschopp. (2008). The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases. Cell Death and Differentiation. 15(11). 1804–1811. 69 indexed citations
8.
Kool, Mirjam, Virginie Pétrilli, Thibaut De Smedt, et al.. (2008). Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome. The Journal of Immunology. 181(6). 3755–3759. 478 indexed citations
9.
Watanabe, Hideki, Samuel Gehrke, Emmanuel Contassot, et al.. (2008). Danger Signaling through the Inflammasome Acts as a Master Switch between Tolerance and Sensitization. The Journal of Immunology. 180(9). 5826–5832. 73 indexed citations
10.
Garner, Elizabeth, Fabio Martinon, Jürg Tschopp, Peter Beard, & Kenneth Raj. (2007). Cells with Defective p53-p21-pRb Pathway Are Susceptible to Apoptosis Induced by p84N5 via Caspase-6. Cancer Research. 67(16). 7631–7637. 21 indexed citations
11.
Martinon, Fabio & Jürg Tschopp. (2006). Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death and Differentiation. 14(1). 10–22. 645 indexed citations breakdown →
12.
Batten, Marcel, Carrie A. Fletcher, Lai Guan Ng, et al.. (2004). TNF Deficiency Fails to Protect BAFF Transgenic Mice against Autoimmunity and Reveals a Predisposition to B Cell Lymphoma. The Journal of Immunology. 172(2). 812–822. 129 indexed citations
13.
Zhang, Jian, Tamás Bárdos, Qing Shao, et al.. (2003). IL-4 Potentiates Activated T Cell Apoptosis Via an IL-2-Dependent Mechanism. The Journal of Immunology. 170(7). 3495–3503. 29 indexed citations
14.
Tschopp, Jürg, Fabio Martinon, & Kim Burns. (2002). The Inflammasome: A Molecular Platform Triggering Activation of Inflammatory Caspases and Processing of proIL-beta: A Molecular Platform Triggering Activation of Inflammatory Caspases and Processing of proIL-beta. Molecular Cell. 417–426. 2 indexed citations
15.
Groom, Joanna R., Susan L. Kalled, Anne H. Cutler, et al.. (2002). Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome. Journal of Clinical Investigation. 109(1). 59–68. 63 indexed citations
16.
Schneider, Pascal, Hisakazu Takatsuka, Anne Wilson, et al.. (2001). Maturation of Marginal Zone and Follicular B Cells Requires B Cell Activating Factor of the Tumor Necrosis Factor Family and Is Independent of B Cell Maturation Antigen. The Journal of Experimental Medicine. 194(11). 1691–1698. 190 indexed citations
17.
Huard, Bertrand, Pascal Schneider, Davide Mauri, Jürg Tschopp, & Lars E. French. (2001). T Cell Costimulation by the TNF Ligand BAFF. The Journal of Immunology. 167(11). 6225–6231. 193 indexed citations
18.
Tschopp, Jürg, Fabio Martinon, & Kay Hofmann. (1999). Apoptosis: Silencing the death receptors. Current Biology. 9(10). R381–R384. 76 indexed citations
19.
Saurat, J.‐H., et al.. (1994). Characterization of human clusterin as a novel secreted stress protein induced by heat shock and oxidative stress in A431 cells. Journal of Investigative Dermatology. 103(3). 421. 1 indexed citations
20.
Krähenbühl, Olivier & Jürg Tschopp. (1991). Perforin-induced pore formation. Immunology Today. 12(11). 399–402. 42 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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