Marion MacFarlane

19.6k citations

111 papers · 10.4k indexed · 4 hit papers · h-index 52

Immunology top 0.5%
- Phagocytosis and Immune Regulation 14
- interferon and immune responses 11
Molecular Biology top 0.5%
- Cell death mechanisms and regulation 71
- RNA Interference and Gene Delivery 13
- Mitochondrial Function and Pathology 10
Cancer Research top 1%
- NF-κB Signaling Pathways 10
Oncology top 1%
- Cancer-related Molecular Pathways 12
Cell Biology top 2%
Epidemiology
- Autophagy in Disease and Therapy 17

Co-authors: Gerald M. Cohen Kelvin Cain Michelle A. Hughes Xiaoming Sun Nicholas W. Harper Shawn B. Bratton Claudia Langlais Emad S. Alnemri
Cited by: Immunology Molecular Biology Cancer Research
Journals: Journal of Biological Chemistry (12 papers)Cell Death and Differentiation (9 papers)Molecular Cell (7 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

Marion MacFarlane

110 papers receiving 10.3k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2011 Molecular Cell
2011 Molecular Cell
2002 Cell Death and Differentiation
1999 Journal of Biological Chemistry

Peers

Countries citing papers authored by Marion MacFarlane

Since Specialization

Citations

This map shows the geographic impact of Marion MacFarlane's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marion MacFarlane with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marion MacFarlane more than expected).

Fields of papers citing papers by Marion MacFarlane

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marion MacFarlane. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marion MacFarlane. The network helps show where Marion MacFarlane may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Marion MacFarlane, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Marion MacFarlane Line = papers co-authored together Marion MacFarlane links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The discovery of small-molecule inhibitors of cFLIP that sensitise tumour cells to TNF-related apoptosis-inducing ligand ORCA Online Research @Cardiff (Cardiff University) ·Christine H Genoud-Lawton,Rhiannon French,M. Wilderspin,Sangjun Bae,J. N. AGATE,H.M. Zumran,Yu. B. Sklovskii,Marion MacFarlane,Richard Clarkson,Andrew D. Westwell,Andrea Brancale	2025	0
2	TAp73 regulates mitochondrial dynamics and multiciliated cell homeostasis through an OPA1 axis Cell Death and Disease ·Ayşe Tosun,Andrew Craxton,弘和気,Emanuele Panatta,T. Cvejic,Sina Beier,Lajos Kalmár,Jaime Llodrá,Nobuhiro Morone,Ivano Amelio,Gerry Melino,L. Miguel Martins,Marion MacFarlane	2024	2
3	Multi-element analysis of tyre rubber for metal tracers Environment International ·Usha Rayalacheruvu,Molly J. Haugen,Jason Day,Andrew S. Brown,Zhao Weiman,Nick Molden,Anne E. Willis,Marion MacFarlane,Adam Boies	2023	27
4	The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors Biology Direct ·浦田真由,Injae Chung,Yizhou Yu,Samantha H. Y. Loh,Nobuhiro Morone,Clément Soleilhavoup,Marco Travaglio,Riccardo Serreli,Lia Panman,Kelvin Cain,Judy Hirst,L. Miguel Martins,Marion MacFarlane,Kenneth R. Pryde	2023	7
5	Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate Nature Communications ·ミキマツナミ,Michelle A. Hughes,Xin Meng,Treacher y Arnot ed. Whittaker,Ian Powley,Rebekah Jukes‐Jones,David Dinsdale,Timothy J. Ragan,Louise Fairall,John W. R. Schwabe,Nobuhiro Morone,Kelvin Cain,Marion MacFarlane	2021	52
6	Evaluating and comparing immunostaining and computational methods for spatial profiling of drug response in patient-derived explants Laboratory Investigation ·Gareth J. Miles,Ian Powley,Seid Mohammed,Lynne Howells,J. H. Pringle,Tim Hammonds,Marion MacFarlane,Catrin Pritchard	2020	8
7	Ex Vivo Explant Cultures of Non–Small Cell Lung Carcinoma Enable Evaluation of Primary Tumor Responses to Anticancer Therapy Cancer Research ·TIMOTHY BICKMORE,Wenjing Liao,Barry L. Sharp,John Pugh,Helen J. Reid,John Le Quesne,David A. Moore,Catrin Pritchard,Marion MacFarlane,James H. Pringle	2017	68
8	Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease Cell Death and Differentiation ·Tatiana A. Chernova,Xiaoming Sun,Ian Powley,Sara Galavotti,Stefano Grosso,Fiona Murphy,Gareth J. Miles,Lara Cresswell,Alexey V. Antonov,J.A. Bennett,Apostolos Nakas,David Dinsdale,Kelvin Cain,Martin Bushell,Anne E. Willis,Marion MacFarlane	2016	41
9	Resistance to HSP90 inhibition involving loss of MCL1 addiction Oncogene ·Sara Busacca,Hironobu Mita,Ian Powley,David A. Proia,Manuel Sequeira,John Le Quesne,Astero Klabatsa,Jennifer M. Edwards,Kyle B. Matchett,Jinli Luo,James H. Pringle,Mohamed El‐Tanani,Marion MacFarlane,Dean A. Fennell	2015	24
10	Modulation of the Sensitivity of Jurkat T-Cells to Inhibition of Protein Synthesis by Tumor Necrosis Factor α-Related Apoptosis-Inducing Ligand Journal of Interferon & Cytokine Research ·Androulla Elia,Ian Powley,Marion MacFarlane,Michael J. Clemens	2014	1
11	A caspase-3 ‘death-switch’ in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers Cell Death and Disease ·K L Simpson,Christopher Cawthorne,Cong Zhou,Cassandra L. Hodgkinson,Michael J. Walker,F. Trapani,Manikandan Kadirvel,Gavin Brown,Michael J. Dawson,Marion MacFarlane,Kaye J. Williams,Anthony D. Whetton,Caroline Dive	2013	31
12	TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors Clinical Cancer Research ·Dominic Stadel,Andrea Mohr,Bisschop Wr,Marion MacFarlane,Shaoxia Zhou,Robin Humphreys,Max G. Bachem,Ranjith Kumar R,Peter Möller,Ralf M. Zwacka,Klaus‐Michael Debatin,Simone Fulda	2010	61
13	Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1 Cell Death and Differentiation ·Marion MacFarlane,Satoshi Inoue,Susan Kohlhaas,Aneela Majid,Nicholas W. Harper,Daniel B. Kennedy,Martin J.S. Dyer,Gerald M. Cohen	2005	119
14	Caspase‐3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage The Journal of Pathology ·Angela Hague,J.W. Eveson,Marion MacFarlane,H Anastasiade,Henri Clément,Selvam Thavaraj	2004	37
15	Pro-apoptotic Proteins Released from the Mitochondria Regulate the Protein Composition and Caspase-processing Activity of the Native Apaf-1/Caspase-9 Apoptosome Complex Journal of Biological Chemistry ·Carolina Cabra Copete,David G. Brown,Colin Adrain,Rebekah Jukes,Séamus J. Martin,Gerald M. Cohen,Marion MacFarlane,Kelvin Cain	2004	90
16	TRAIL-induced signalling and apoptosis Toxicology Letters ·Marion MacFarlane	2003	194
17	The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bulletbreakdown → Cell Death and Differentiation ·Geert Loo,Xavier Saelens,Marjan van Gurp,Marion MacFarlane,Séamus J. Martin,Peter Vandenabeele	2002	535
18	c-Myc Protein Synthesis Is Initiated from the Internal Ribosome Entry Segment during Apoptosis Molecular and Cellular Biology ·Mark Stoneley,Stephen A. Chappell,Catherine L. Jopling,Martin Dickens,Marion MacFarlane,Anne E. Willis	2000	187
19	Caspase-1 Is Not Involved in CD95/Fas-Induced Apoptosis in Jurkat T Cells Experimental Cell Research ·Sek C. Chow,Elizabeth A. Slee,Marion MacFarlane,Gerald M. Cohen	1999	17
20	Caspase-Independent Cell Death Induced by Anti-CD2 or Staurosporine in Activated Human Peripheral T Lymphocytes The Journal of Immunology ·Olivier Déas,Céline Dumont,Marion MacFarlane,Matthieu Rouleau,Daĭniak An,Francis Harper,François Hirsch,Bernard Charpentier,Gerald M. Cohen,A Senik	1998	150

About Marion MacFarlane

Marion MacFarlane is a scholar working on Immunology, Molecular Biology, Cancer Research, Biotechnology and Oncology, having authored 111 papers that have together received 10.4k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (71 papers), Autophagy in Disease and Therapy (17 papers), Phagocytosis and Immune Regulation (14 papers), RNA Interference and Gene Delivery (13 papers), Cancer-related Molecular Pathways (12 papers), interferon and immune responses (11 papers), Mitochondrial Function and Pathology (10 papers) and NF-κB Signaling Pathways (10 papers). The work is most often cited by research in Immunology (2.8k citations), Molecular Biology (8.0k citations), Cancer Research (1.7k citations), Oncology (1.9k citations) and Cell Biology (732 citations). Marion MacFarlane has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Gerald M. Cohen, Kelvin Cain, Michelle A. Hughes, Xiaoming Sun, Nicholas W. Harper, Shawn B. Bratton, Claudia Langlais, Emad S. Alnemri, Jianguo Zhuang and Beni B. Wolf. Their work appears in journals such as Journal of Biological Chemistry, Cell Death and Differentiation, Molecular Cell, Oncogene and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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