Patrick R. Griffin

36.8k citations

340 papers · 23.4k indexed · 6 hit papers · h-index 75

Impact in

Molecular Biology top 0.2%
- Peroxisome Proliferator-Activated Receptors
- Cell death mechanisms and regulation
- Receptor Mechanisms and Signaling
- Metabolism, Diabetes, and Cancer
Spectroscopy top 0.2%
- Mass Spectrometry Techniques and Applications
- Advanced Proteomics Techniques and Applications

Papers in

Molecular Biology 190
- Peroxisome Proliferator-Activated Receptors 42
- Receptor Mechanisms and Signaling 39
- Metabolism, Diabetes, and Cancer 28
Spectroscopy 39
- Mass Spectrometry Techniques and Applications 37
- Analytical Chemistry and Chromatography 17

Co-authors: Michael J. Chalmers Theodore M. Kamenecka Scott A. Busby Bruce D. Pascal Nancy A. Thornberry Ting-Ting Yamin Thomas P. Burris Marc Labelle
Journals: Journal of Biological Chemistry (23 papers)Nature Communications (19 papers)Proceedings of the National Academy of Sciences (16 papers)Structure (13 papers)Biochemistry (12 papers)
Partner nations: United States China Australia

In The Last Decade

Patrick R. Griffin

331 papers receiving 22.6k citations

Hit Papers

6 papers align trajectories log scale

HP1 reshapes nucleosome core to promote phase separation of heterochromatin 2019 · 336 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Nature
2011 Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B))
2010 Nature
2000 Nature
1995 Nature
1993 Analytical Biochemistry

Peers

Countries citing papers authored by Patrick R. Griffin

Since Specialization

Citations

This map shows the geographic impact of Patrick R. Griffin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick R. Griffin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick R. Griffin more than expected).

Fields of papers citing papers by Patrick R. Griffin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick R. Griffin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick R. Griffin. The network helps show where Patrick R. Griffin may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Patrick R. Griffin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick R. Griffin Line = papers co-authored together Patrick R. Griffin links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2 SLAS DISCOVERY ·Emery Smith, Meredith E. Davis-Gardner, Rubén D. Garcia-Ordoñez, Webb-Robertson Bobbie-Jo, Mitchell Hull, Emily Chen, Xuerong Yu, Thomas D. Bannister, Pierre Baillargeon, Louis Scampavia, Patrick R. Griffin, Michael Farzan, Timothy Spicer	2023	13
2	PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles ACS Chemical Biology ·Rebecca L. Frkic, S. Krawetz, Dennis M. Sweeny, Blagojce Jovcevski‬, 卢金珠, Wioleta Kowalczyk, Tara L. Pukala, Mi Ra Chang, Jie Zheng, Anne‐Laure Blayo, Andrew D. Abell, Theodore M. Kamenecka, Evelyne Farges Uldry, Jeffrey R. Harmer, Patrick R. Griffin, John B. Bruning	2023	5
3	Evaluation of the GaAs Displacement Damage Metric using Updated Nuclear Data. OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) ·Ji Young Yang, William Charlton, Patrick R. Griffin	2022	1
4	Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection Nature Communications ·Guochao Wei, Mustafa Arık, Valentine V. Courouble, Ashwanth C. Francis, Parmit K. Singh, Arpa Hudait, Arun S. Annamalai, S.M. Bester, Szu‐Wei Huang, Nikoloz Shkriabai, Gregory Douglas Funk, O.V. Rozhkova, Vineet N. KewalRamani, Gregory A. Voth, Alan Engelman, Gregory B. Melikyan, Patrick R. Griffin, Francisco J. Asturias, Mamuka Kvaratskhelia	2022	32
5	Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro Science Advances ·Ruchi Yadav, Valentine V. Courouble, Sanjay Kumar Dey, مولف علیاکبر متواضع, Jennifer Timm, Jesse B. Hopkins, J Sunarso, Stefan G. Sarafianos, Francesc X. Ruiz, Patrick R. Griffin, Eddy Arnold	2022	18
6	Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket Journal of Medicinal Chemistry ·John Charles Torres Vásquez, Antoine Gallet, Armel Cyrille Tenkeu, Valentine V. Courouble, Anamika Patel, M Gehrisch, Alyssa M. Johnson, C. Denise Okafor, Filipp Frank, Emma H. D’Agostino, Patrick R. Griffin, Nathan T. Jui, Eric A. Ortlund	2022	6
7	Safety Culture and Risk Management in Agriculture : Sacurima Cost Action CA16123 Highlights and Conclusions Jukuri (Luonnonvarakeskus Tietopalvelu) ·Pascal Hauk, Patrick R. Griffin, John McNamara, Risto Rautiainen	2021	3
8	Structures of the human LONP1 protease reveal regulatory steps involved in protease activation Nature Communications ·Mia Shin, Edmond R. Watson, Albert S. Song, Jeffrey T. Mindrebo, Scott J. Novick, Patrick R. Griffin, R. Luke Wiseman, Gabriel C. Lander	2021	46
9	Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II ACS Chemical Biology ·László Radnai, M. D. Surman, R.G. Sargent, Erica J. Young, Neyva Cristina, Li Lin, Brigitte Roberge, Huihong Jin, Eun Sun Park, J. H. Kim, Srinivasa Kruthyventi Prabhu, Anne Diehl, Eilis M. Gillespie, James R. Sellers, Michael D. Cameron, Gavin Rumbaugh, Patrick R. Griffin, Theodore M. Kamenecka, Courtney A. Miller	2021	4
10	A molecular switch regulating transcriptional repression and activation of PPARγ Nature Communications ·Jinsai Shang, Sarah A. Mosure, Jie Zheng, Richard Brust, Chiea Chuan Khor, Christopher Kasanke, Laura A. Solt, Patrick R. Griffin, Douglas J. Kojetin	2020	55
11	Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase Nucleic Acids Research ·楊玉麟, Jie Zheng, Javier Narváez, Liming Qiu, Dong Zhang, Steve Tuske, Margaret J. Lange, Patrick R. Griffin, Eddy Arnold, Shi‐Jie Chen, Xiaoqin Zou, Xiao Heng, Donald H. Burke	2020	26
12	Structural and Functional Studies of Chikungunya Virus nsP2 SHILAP Revista de lepidopterología ·Yee-Song Law, Yaw Bia Tan, Orion Shih, Age Utt, Jie Zheng, Sainan Wang, Ming Wei Chen, Patrick R. Griffin, U‐Ser Jeng, Andres Merits, Dahai Luo	2020	1
13	Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions Analytical Chemistry ·Jie Zheng, Timothy S. Strutzenberg, Adrian Reich, Venkatasubramanian Dharmarajan, Bruce D. Pascal, Gogce Crynen, Scott J. Novick, Rubén D. Garcia-Ordoñez, Patrick R. Griffin	2020	16
14	Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer SHILAP Revista de lepidopterología ·Steve Tuske, Jie Zheng, Erik D. Olson, Francesc X. Ruiz, Bruce D. Pascal, Anthony Hoang, Joseph D. Bauman, Kalyan Das, Jeffrey J. DeStefano, Karin Musier‐Forsyth, Patrick R. Griffin, Eddy Arnold	2020	9
15	Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling Nature Communications ·Ali Shahabaddini, Cynthia M. Chio, Venkatasubramanian Dharmarajan, Michael J. Trnka, Andreja Cavnik, Devrishi Goswami, 幸彦中川, Alma L. Burlingame, Patrick R. Griffin, Danica Galonić Fujimori	2019	37
16	The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator Journal of Biological Chemistry ·Clint D.J. Tavares, Kfir Sharabi, John E. Dominy, Yoonjin Lee, Marta Isasa, Jose M. Orozco, Mark P. Jedrychowski, Theodore M. Kamenecka, Patrick R. Griffin, Steven P. Gygi, Pere Puigserver	2016	34
17	Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation eLife ·Sean W. Fanning, Christopher G. Mayne, Venkatasubramanian Dharmarajan, Kathryn E. Carlson, Teresa A. Martin, Scott J. Novick, Weiyi Toy, Safaa Mohammed Zaki, Normah Ismail, Benita S. Katzenellenbogen, Emad Tajkhorshid, Patrick R. Griffin, Yang Shen, Sarat Chandarlapaty, John A. Katzenellenbogen, Geoffrey L. Greene	2016	215
18	The People with No Name Princeton University Press eBooks ·Patrick R. Griffin	2012	14
19	Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method Proceedings of the National Academy of Sciences ·Susie Y. Dai, Michael J. Chalmers, John B. Bruning, Kelli Bramlett, Harold E. Osborne, Chahrzad Montrose‐Rafizadeh, Robert J. Barr, Yong Wang, Minmin Wang, Thomas P. Burris, Jeffrey A. Dodge, Patrick R. Griffin	2008	68
20	A new small myotoxin from the venom of the prairie rattlesnake (Crotalus viridis viridis) FEBS Letters ·Patrick R. Griffin, Steven D. Aird	1990	24

About Patrick R. Griffin

Patrick R. Griffin is a scholar working on Molecular Biology, Spectroscopy, Cellular and Molecular Neuroscience, Genetics and Virology, having authored 340 papers that have together received 23.4k indexed citations. Recurring topics across this work include Peroxisome Proliferator-Activated Receptors (42 papers), Receptor Mechanisms and Signaling (39 papers), Mass Spectrometry Techniques and Applications (37 papers), Estrogen and related hormone effects (34 papers), Metabolism, Diabetes, and Cancer (28 papers), Adipose Tissue and Metabolism (22 papers), Analytical Chemistry and Chromatography (17 papers) and Inflammatory mediators and NSAID effects (15 papers). The work is most often cited by research in Molecular Biology (13.1k citations), Spectroscopy (2.2k citations), Immunology (2.4k citations), Endocrine and Autonomic Systems (738 citations) and Biochemistry (748 citations). Patrick R. Griffin has collaborated with scholars based in United States, China and Australia. Frequent co-authors include Michael J. Chalmers, Theodore M. Kamenecka, Scott A. Busby, Bruce D. Pascal, Nancy A. Thornberry, Ting-Ting Yamin, Thomas P. Burris, Marc Labelle, Yves Gareau and Michel Gallant. Their work appears in journals such as Journal of Biological Chemistry, Nature Communications, Proceedings of the National Academy of Sciences, Structure and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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