Andréa C. LeBlanc

9.1k citations

103 papers · 6.9k indexed · 1 hit paper · h-index 44

Molecular Biology top 1%
Physiology top 0.5%
Neurology top 0.5%
Cellular and Molecular Neuroscience top 1%
Cell Biology top 1%

Co-authors: Cynthia G. Goodyer Maria Koutroumanis Jennifer Hammond Joseph F. Poduslo Bénédicte Foveau Éric Paradis Joseph Flores Xavier Roucou
Topics: Alzheimer's disease research and treatments (37 papers)Prion Diseases and Protein Misfolding (23 papers)Cell death mechanisms and regulation (15 papers)
Cited by: Neurology Biological Psychiatry Physiology
Journals: Cell Journal of Biological Chemistry Nature Communications
Partner nations: Canada United States Brazil

In The Last Decade

Andréa C. LeBlanc

103 papers receiving 6.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

1999 673 citations François G. Gervais, Daigen Xu et al. Cell profile →

Peers

Countries citing papers authored by Andréa C. LeBlanc

Since Specialization

Citations

This map shows the geographic impact of Andréa C. LeBlanc's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andréa C. LeBlanc with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andréa C. LeBlanc more than expected).

Fields of papers citing papers by Andréa C. LeBlanc

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andréa C. LeBlanc. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andréa C. LeBlanc. The network helps show where Andréa C. LeBlanc may publish in the future.

Co-authorship network of co-authors of Andréa C. LeBlanc

This figure shows the co-authorship network connecting the top 25 collaborators of Andréa C. LeBlanc. A scholar is included among the top collaborators of Andréa C. LeBlanc based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andréa C. LeBlanc. Andréa C. LeBlanc is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging 2020 ·Nature Communications ·Joseph Flores,Anastasia Noël,Bénédicte Foveau,Olivier Beauchet,Andréa C. LeBlanc	67
2	Identification of Allosteric Inhibitors against Active Caspase-6 2019 ·Scientific Reports ·(unknown),Alexandre Beautrait,(unknown),Gyanesh Sharma,A. Gorelik,(unknown),Naoto Soya,Gergely L. Lukács,Bhushan Nagar,Anne Marinier,Andréa C. LeBlanc	19
3	Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity 2018 ·Scientific Reports ·(unknown),Libin Zhou,Gyanesh Sharma,(unknown),Sergey N. Savinov,Jeanne A. Hardy,Andréa C. LeBlanc	9
4	Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation. 2015 ·PMC ·Vandana Kaushal,(unknown),Prateep Pakavathkumar,Bénédicte Foveau,Joseph Flores,Bradley T. Hyman,Bernardino Ghetti,Beverly H. Koller,Andréa C. LeBlanc	4
5	Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation 2015 ·Cell Death and Differentiation ·Vandana Kaushal,(unknown),Prateep Pakavathkumar,Bénédicte Foveau,Joseph Flores,Bradley T. Hyman,Bernardino Ghetti,Beverly H. Koller,Andréa C. LeBlanc	247
6	Cyclin-dependent Kinase 5 Phosphorylation of Familial Prion Protein Mutants Exacerbates Conversion into Amyloid Structure 2015 ·Journal of Biological Chemistry ·Raphaël Rouget,Gyanesh Sharma,Andréa C. LeBlanc	3
7	Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment 2014 ·Cell Death and Differentiation ·Andréa C. LeBlanc,(unknown),Veronica M. Afonso,Édith Hamel,David A. Bennett,Prateep Pakavathkumar,Steffen Albrecht	42
8	Caspase-6 activity predicts lower episodic memory ability in aged individuals 2013 ·Neurobiology of Aging ·(unknown),Veronica M. Afonso,Steffen Albrecht,David A. Bennett,Andréa C. LeBlanc	35
9	Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures. 2010 ·Cell Death and Disease ·Saskia Sivananthan,(unknown),Cynthia G. Goodyer,Andréa C. LeBlanc	39
10	Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein or Presenilin I or Presenilin II Mutations 2009 ·Journal of Neuropathology & Experimental Neurology ·Steffen Albrecht,Nenad Bogdanović,Bernardino Ghetti,Bengt Winblad,Andréa C. LeBlanc	65
11	Self-activation of Caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells 2008 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·(unknown),Nathalie Champagne,Andréa C. LeBlanc	82
12	Proteasomal degradation of caspase‐6 in 17β‐estradiol‐treated neurons 2004 ·Journal of Neurochemistry ·Omar Tounekti,Yan Zhang,(unknown),Cynthia G. Goodyer,Andréa C. LeBlanc	15
13	Canadian Association of Neuropathologists Abstracts of papers and cases presented at the 41st Annual Meeting 2001 ·Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ·Sheila Tobias,Yves Robitaille,William F. Hickey,Craig Rhodes,Rachel Nordgren,Frédérick Andermann,Jean‐Pierre Julien,Andréa C. LeBlanc,(unknown)	1
14	Prion Protein Protects Human Neurons against Bax-mediated Apoptosis 2001 ·Journal of Biological Chemistry ·(unknown),Yan Zhang,Cynthia G. Goodyer,Andréa C. LeBlanc	285
15	Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formationbreakdown → 1999 ·Cell ·François G. Gervais,Daigen Xu,George S. Robertson,John P. Vaillancourt,(unknown),Jingqi Huang,Andréa C. LeBlanc,David W. Smith,Michael Rigby,Mark S. Shearman,Earl E. Clarke,Hui Zheng,(unknown),(unknown),Nancy A. Thornberry,(unknown),Robert Zamboni,Sophie Roy,Donald W. Nicholson	673
16	Processing of Amyloid Precursor Protein in Human Primary Neuron and Astrocyte Cultures 1997 ·Journal of Neurochemistry ·Andréa C. LeBlanc,Maria Papadopoulos,(unknown),(unknown),(unknown),(unknown),Cynthia G. Goodyer	69
17	A role for extracellular matrix degradation and matrix metalloproteinases in senile dementia? 1994 ·Acta Neuropathologica ·A. Bignami,Andréa C. LeBlanc,George Perides	19
18	The role of β-amyloid peptide in alzheimer's disease 1994 ·Metabolic Brain Disease ·Andréa C. LeBlanc	6
19	P0 gene expression in Schwann cells is modulated by an increase of cAMP which is dependent on the presence of axons 1992 ·Molecular Brain Research ·Andréa C. LeBlanc,Anthony J. Windebank,Joseph F. Poduslo	38
20	Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures 1991 ·FEBS Letters ·Andréa C. LeBlanc,H. Y. Chen,L. Autilio‐Gambetti,Pierluigi Gambetti	57

About Andréa C. LeBlanc

Andréa C. LeBlanc is a scholar working on Neurology, Physiology and Cell Biology, having authored 103 papers that have together received 6.9k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (37 papers), Prion Diseases and Protein Misfolding (23 papers) and Cell death mechanisms and regulation (15 papers). The work is most often cited by research in Neurology (1.4k citations), Biological Psychiatry (267 citations) and Physiology (2.6k citations). Andréa C. LeBlanc has collaborated with scholars based in Canada, United States and Brazil. Frequent co-authors include Cynthia G. Goodyer, Cynthia G. Goodyer, Maria Koutroumanis, Jennifer Hammond, Joseph F. Poduslo, Bénédicte Foveau, Éric Paradis, Joseph Flores, Xavier Roucou and Yan Zhang. Their work appears in journals such as Cell, Journal of Biological Chemistry and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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