Violeta Yu

5.3k citations

29 papers · 4.4k indexed · 1 hit paper · h-index 15

Impact in

Molecular Biology top 2%
- Cell death mechanisms and regulation
- RNA Interference and Gene Delivery
- Mitochondrial Function and Pathology
Immunology top 5%
- interferon and immune responses

Papers in ⓘ

Molecular Biology 19
- Ion channel regulation and function 7
- Receptor Mechanisms and Signaling 3
- Epigenetics and DNA Methylation 3
- Melanoma and MAPK Pathways 2
Oncology 9
- Cytokine Signaling Pathways and Interactions 4

Co-authors: Donald W. Nicholson (3 shared papers)Douglas K. Miller (2 shared papers)John P. Vaillancourt (2 shared papers)Ting-Ting Yamin (2 shared papers)Ambereen Ali (2 shared papers)Mark E. Smulson (1 shared paper)Nancy A. Thornberry (1 shared paper)Marc Labelle (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)SLAS DISCOVERY (3 papers)Assay and Drug Development Technologies (3 papers)Journal of Medicinal Chemistry (3 papers)Journal of Biological Chemistry (2 papers)
Partner nations: United States Canada Switzerland

In The Last Decade

Violeta Yu

29 papers receiving 4.3k citations

Hit Papers

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis 1995 · 3.6k citations

Peers

Countries citing papers authored by Violeta Yu

Since Specialization

Citations

This map shows the geographic impact of Violeta Yu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Violeta Yu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Violeta Yu more than expected).

Fields of papers citing papers by Violeta Yu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Violeta Yu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Violeta Yu. The network helps show where Violeta Yu may publish in the future.

Co-authors

The 25 scholars most cited alongside Violeta Yu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Violeta Yu Line = papers co-authored together Violeta Yu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 29 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis Nature ·Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry, John P. Vaillancourt, Connie K. Ding, Michel Gallant, Yves Gareau, Patrick R. Griffin, Marc Labelle, Yuri Lazebnik, Neil A. Munday, Sayyaparaju M. Raju, Mark E. Smulson, Ting-Ting Yamin, Violeta Yu, Douglas K. Miller Hit paper breakdown →	1995	3612
2	Molecular Cloning and Pro-apoptotic Activity of ICErelII and ICErelIII, Members of the ICE/CED-3 Family of Cysteine Proteases Journal of Biological Chemistry ·Neil A. Munday, John P. Vaillancourt, Ambereen Ali, Francesca J. Casano, Douglas K. Miller, Susan M. Molineaux, Ting-Ting Yamin, Violeta Yu, Donald W. Nicholson	1995	247
3	Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology Analytical Biochemistry ·Jennifer Dao, Robert J. Kurzeja, Jose M. Morachis, Henrike Veith, Jeffery K. Lewis, Violeta Yu, Christopher M. Tegley, Philip Tagari	2008	63
4	Generation and Functional Characterization of Arylamine N-Acetyltransferase Nat1/Nat2Double-Knockout Mice Molecular Pharmacology ·Kim S. Sugamori, Sharon Y. Wong, Andrea Gaedigk, Violeta Yu, Hanan Abramovici, Richard Rozmahel, Denis M. Grant	2003	62
5	Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase Bioorganic & Medicinal Chemistry Letters ·Nuria Tamayo, Lillian Liao, Martin H. Goldberg, David Powers, Yanyan Tudor, Violeta Yu, Lu Min Wong, Bradley Henkle, Scot Middleton, Rashid Syed, Timothy S. Harvey, Graham Jang, Randall W. Hungate, Celia Dominguez	2005	40
6	Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity Journal of Medicinal Chemistry ·Laurie B. Schenkel, Philip R. Olivieri, Alessandro A. Boezio, Holly L. Deak, Renee Emkey, Russell F. Graceffa, Hakan Günaydin, Angel Guzmán-Pérez, Josie H. Lee, Yohannes Teffera, Weiya Wang, Beth D. Youngblood, Violeta Yu, Maosheng Zhang, Narender R. Gavva, Sonya G. Lehto, Stephanie Geuns-Meyer	2016	40
7	The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer Journal of Medicinal Chemistry ·Richard T. Lewis, Christiane Bode, Deborah M. Choquette, Michele Potashman, Karina Romero, John Stellwagen, Yohannes Teffera, Earl Moore, Douglas A. Whittington, Hao Chen, Linda F. Epstein, Renee Emkey, Paul S. Andrews, Violeta Yu, Douglas C. Saffran, Man Xu, Allison E. Drew, Patricia Merkel, Steven Szilvassy, Rachael Brake	2012	38
8	Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit Journal of Medicinal Chemistry ·Essa Hu, Andrew S. Tasker, Ryan D. White, Roxanne K. Kunz, Jason Human, Ning Chen, Roland W. Bürli, Randall W. Hungate, Perry M. Novak, Andrea Itano, Xuxia Zhang, Violeta Yu, Yen Nguyen, Yanyan Tudor, Matthew Plant, Shaun Flynn, Yang Xu, Kristin L. Meagher, Douglas A. Whittington, Gordon Ng	2008	37
9	Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V PLoS ONE ·Bryan D. Moyer, Justin K. Murray, Joseph Ligutti, Kristin L. Andrews, Philippe Favreau, John B. Jordan, Josie H. Lee, Dong Liu, Jason Long, Kelvin Sham, Licheng Shi, Reto Stöcklin, Bin Wu, Ruoyuan Yin, Violeta Yu, Anruo Zou, Kaustav Biswas, Les P. Miranda	2018	35
10	High-Throughput TR-FRET Assays for Identifying Inhibitors of LSD1 and JMJD2C Histone Lysine Demethylases SLAS DISCOVERY ·Violeta Yu, Tanja Fisch, Alexander Long, Jin Tang, Josie Han Lee, Markus Hierl, Hao Chen, P. Yakowec, Ralf Schwandner, Renee Emkey	2011	31
11	Small molecules with potent osteogenic-inducing activity in osteoblast cells Bioorganic & Medicinal Chemistry Letters ·Chun-Ya Han, Youping Wang, Longchuan Yu, David Powers, Xiaoling Xiong, Violeta Yu, Yen Nguyen, David J. St. Jean, Philip Babij	2009	25
12	KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury Cell stem cell ·Jesse D. Lai, Joshua Berlind, Gabriella Fricklas, Cecilia Lie, Jean‐Paul Urenda, Kelsey Lam, Naomi S. Sta Maria, Russell E. Jacobs, Violeta Yu, Zhen Zhao, Justin K. Ichida	2024	22
13	Differential selectivity of JAK2 inhibitors in enzymatic and cellular settings Experimental Hematology ·Violeta Yu, Jeanne Pistillo, Ivonne Archibeque, Josie Han Lee, Bee-Chun Sun, Laurie B. Schenkel, Stephanie Geuns-Meyer, Liqin Liu, Renee Emkey	2013	20
14	Development and Implementation of a High-Throughput AlphaLISA Assay for Identifying Inhibitors of EZH2 Methyltransferase Assay and Drug Development Technologies ·Jeffrey R. Simard, Matthew Plant, Renee Emkey, Violeta Yu	2013	16
15	High-Content Screening Analysis of the p38 Pathway: Profiling of Structurally Related p38 α Kinase Inhibitors Using Cell-Based Assays Assay and Drug Development Technologies ·Sandra L. Ross, Teresa C. Chen, Violeta Yu, Yanyan Tudor, Dawei Zhang, Longbin Liu, Nuria Tamayo, Celia Dominguez, David Powers	2006	15
16	Epitope-labeled Soluble Human Interleukin-5 (IL-5) Receptors Journal of Biological Chemistry ·Pamela M. Brown, Philip Tagari, Kevin Rowan, Violeta Yu, Gary P. O’Neill, C. Russell Middaugh, Gautam Sanyal, Anthony W. Ford‐Hutchinson, Donald W. Nicholson	1995	14
17	Discovery of amido-benzisoxazoles as potent c-Kit inhibitors Bioorganic & Medicinal Chemistry Letters ·Roxanne K. Kunz, Shannon Rumfelt, Ning Chen, Dawei Zhang, Andrew S. Tasker, Roland W. Bürli, Randall W. Hungate, Violeta Yu, Yen Nguyen, Douglas A. Whittington, Kristin L. Meagher, Matthew Plant, Yanyan Tudor, Michael Schrag, Yang Xu, Gordon Ng, Essa Hu	2008	10
18	Abstract 1795: Characterization of a novel series of potent, selective inhibitors of wild type and mutant/fusion anaplastic lymphoma kinase Cancer Research ·Keith Wilcoxen, Rachael Brake, Doug Saffran, Yohannes Teffera, Deborah M. Choquette, Doug Whittington, Violeta Yu, Karina Romero, Christiane Bode, John Stellwagen, Michelle Potashman, Renee Emkey, Paul S. Andrews, Allison E. Drew, Man Xu, Stephen J. Szilvassy, Samer Al-Assad, Richard T. Lewis	2012	10
19	1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of NaV1.7 inhibition Bioorganic & Medicinal Chemistry Letters ·Alessandro A. Boezio, Kristin L. Andrews, Christiane Boezio, Margaret Y. Chu‐Moyer, Katrina W. Copeland, Erin F. DiMauro, R. Foti, Robert T. Fremeau, Hua Gao, Stephanie Geuns-Meyer, Russell F. Graceffa, Hakan Günaydin, Hongbing Huang, Daniel S. La, Joseph Ligutti, Bryan D. Moyer, Emily A. Peterson, Violeta Yu, Matthew M. Weiss	2018	8
20	Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors Bioorganic & Medicinal Chemistry Letters ·Laurie B. Schenkel, Erin F. DiMauro, Hanh Nho Nguyen, Nagasree Chakka, Bingfan Du, R. Foti, Angel Guzmán-Pérez, Michael Jarosh, Daniel S. La, Joseph Ligutti, Benjamin C. Milgram, Bryan D. Moyer, Emily A. Peterson, John G. Roberts, Violeta Yu, Matthew M. Weiss	2017	6

About Violeta Yu

Violeta Yu is a scholar working on Molecular Biology, Oncology, Genetics, Organic Chemistry and Cellular and Molecular Neuroscience, having authored 29 papers that have together received 4.4k indexed citations. Recurring topics across this work include Ion channel regulation and function (7 papers), Cytokine Signaling Pathways and Interactions (4 papers), Myeloproliferative Neoplasms: Diagnosis and Treatment (3 papers), Chronic Lymphocytic Leukemia Research (3 papers), Receptor Mechanisms and Signaling (3 papers), Epigenetics and DNA Methylation (3 papers), Lung Cancer Treatments and Mutations (3 papers) and Melanoma and MAPK Pathways (2 papers). The work is most often cited by research in Molecular Biology (3.2k citations), Immunology (774 citations), Cancer Research (483 citations), Toxicology (102 citations) and Oncology (768 citations). Violeta Yu has collaborated with scholars based in United States, Canada and Switzerland. Frequent co-authors include Donald W. Nicholson, Douglas K. Miller, John P. Vaillancourt, Ting-Ting Yamin, Ambereen Ali, Mark E. Smulson, Nancy A. Thornberry, Marc Labelle, Yves Gareau and Patrick R. Griffin. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, SLAS DISCOVERY, Assay and Drug Development Technologies, Journal of Medicinal Chemistry and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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