Nancy A. Thornberry

40.1k total citations · 7 hit papers
110 papers, 26.3k citations indexed

About

Nancy A. Thornberry is a scholar working on Molecular Biology, Oncology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Nancy A. Thornberry has authored 110 papers receiving a total of 26.3k indexed citations (citations by other indexed papers that have themselves been cited), including 62 papers in Molecular Biology, 50 papers in Oncology and 38 papers in Cellular and Molecular Neuroscience. Recurrent topics in Nancy A. Thornberry's work include Peptidase Inhibition and Analysis (40 papers), Neuropeptides and Animal Physiology (36 papers) and Diabetes Treatment and Management (36 papers). Nancy A. Thornberry is often cited by papers focused on Peptidase Inhibition and Analysis (40 papers), Neuropeptides and Animal Physiology (36 papers) and Diabetes Treatment and Management (36 papers). Nancy A. Thornberry collaborates with scholars based in United States, Canada and Japan. Nancy A. Thornberry's co-authors include Yuri Lazebnik, Donald W. Nicholson, Erin P. Peterson, John P. Vaillancourt, Sophie Roy, Margarita García‐Calvo, Douglas K. Miller, Ting-Ting Yamin, Antony Rosen and Patrick R. Griffin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Nancy A. Thornberry

110 papers receiving 25.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Caspases: Enemies Within

1998 5.9k citations Nancy A. Thornberry et al. profile →
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1995 3.6k citations Donald W. Nicholson, Nancy A. Thornberry et al. profile →
Caspases: killer proteases

1997 2.1k citations Donald W. Nicholson, Nancy A. Thornberry profile →
A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

1997 1.8k citations Nancy A. Thornberry, Thomas A. Rano et al. Journal of Biological Chemistry profile →
Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors

1998 859 citations Margarita García‐Calvo, Erin P. Peterson et al. Journal of Biological Chemistry profile →
Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

1999 673 citations François G. Gervais, Daigen Xu et al. Cell profile →
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.

1996 563 citations Livia Casciola‐Rosen, Donald W. Nicholson et al. The Journal of Experimental Medicine profile →

Peers

Countries citing papers authored by Nancy A. Thornberry

Since Specialization

Citations

This map shows the geographic impact of Nancy A. Thornberry's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nancy A. Thornberry with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nancy A. Thornberry more than expected).

Fields of papers citing papers by Nancy A. Thornberry

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nancy A. Thornberry. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nancy A. Thornberry. The network helps show where Nancy A. Thornberry may publish in the future.

Co-authorship network of co-authors of Nancy A. Thornberry

This figure shows the co-authorship network connecting the top 25 collaborators of Nancy A. Thornberry. A scholar is included among the top collaborators of Nancy A. Thornberry based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nancy A. Thornberry. Nancy A. Thornberry is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A comparative study of the binding properties, dipeptidyl peptidase‐4 (DPP‐4) inhibitory activity and glucose‐lowering efficacy of the DPP‐4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice 2017 ·Endocrinology Diabetes & Metabolism ·Joel P. Berger, Ranabir SinhaRoy, Alessandro Pocai, Theresa M. Kelly, Giovanna Scapin, Ying‐Duo Gao, (unknown), Joseph K. Wu, George J. Eiermann, Shiyao Xu, Xiaoping Zhang, Daniel Tatosian, Ann E. Weber, Nancy A. Thornberry, Richard D. Carr	67
2	Optimization of co‐agonism at GLP‐1 and glucagon receptors to safely maximize weight reduction in DIO‐rodents 2012 ·Biopolymers ·Jonathan W. Day, Vasily M. Gelfanov, David L. Smiley, Paul E. Carrington, George J. Eiermann, Gary G. Chicchi, Mark D. Erion, (unknown), Nancy A. Thornberry, Matthias H. Tschöp, Donald J. Marsh, Ranabir SinhaRoy, Richard D. DiMarchi, Alessandro Pocai	111
3	Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design 2008 ·Bioorganic & Medicinal Chemistry Letters ·Gui‐Bai Liang, Xiaoxia Qian, Tesfaye Biftu, Suresh B. Singh, Ying‐Duo Gao, Giovanna Scapin, Sangita B. Patel, Barbara Leiting, Reshma A. Patel, Joseph K. Wu, Xiaoping Zhang, Nancy A. Thornberry, Ann E. Weber	20
4	Enzymatic Activity of the Staphylococcus aureus SplB Serine Protease is Induced by Substrates Containing the Sequence Trp-Glu-Leu-Gln 2008 ·Journal of Molecular Biology ·Grzegorz Dubin, (unknown), (unknown), Katarzyna Pustelny, Grzegorz M. Popowicz, Michał Biśta, Tomasz Kantyka, Kevin T. Boulware, Henning R. Stennicke, Anna Czarna, (unknown), Patrick S. Daugherty, Ida B. Thøgersen, Jan J. Enghild, Nancy A. Thornberry, Adam Dubin, Jan Potempa	39
5	4-Arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV 2007 ·Bioorganic & Medicinal Chemistry Letters ·David E. Kaelin, (unknown), George J. Eiermann, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Reshma A. Patel, Sangita B. Patel, (unknown), Giovanna Scapin, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber, Joseph Duffy	17
6	Optimization of 1,4-diazepan-2-one containing dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes 2007 ·Bioorganic & Medicinal Chemistry Letters ·Gui‐Bai Liang, Xiaoxia Qian, Dennis Feng, Tesfaye Biftu, George J. Eiermann, Huaibing He, Barbara Leiting, Kathy Lyons, Aleksandr Petrov, Ranabir SinhaRoy, Bei Zhang, Joseph K. Wu, Xiaoping Zhang, Nancy A. Thornberry, Ann E. Weber	27
7	Dipeptidyl Peptidase-4 Inhibitors for the Treatment of Type 2 Diabetes: Focus On Sitagliptin 2007 ·Clinical Pharmacology & Therapeutics ·Gary Herman, Peter P. Stein, Nancy A. Thornberry, John A. Wagner	135
8	Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors 2005 ·Bioorganic & Medicinal Chemistry Letters ·Jinyou Xu, Lan Wei, Robert J. Mathvink, Scott D. Edmondson, Anthony Mastracchio, George J. Eiermann, Huaibing He, Joseph F. Leone, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel, Aleksandr Petrov, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber	14
9	The Caspase-like Sites of Proteasomes, Their Substrate Specificity, New Inhibitors and Substrates, and Allosteric Interactions with the Trypsin-like Sites 2003 ·Journal of Biological Chemistry ·Alexei F. Kisselev, Margarita García‐Calvo, Herman S. Overkleeft, Erin P. Peterson, Michael W. Pennington, Hidde L. Ploegh, Nancy A. Thornberry, Alfred L. Goldberg	158
10	Determination of Caspase Specificities Using a Peptide Combinatorial Library 2000 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Nancy A. Thornberry, Kevin T. Chapman, Donald W. Nicholson	50
11	Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation breakdown → 1999 ·Cell ·François G. Gervais, Daigen Xu, George S. Robertson, John P. Vaillancourt, (unknown), Jingqi Huang, Andréa C. LeBlanc, David W. Smith, Michael Rigby, Mark S. Shearman, Earl E. Clarke, Hui Zheng, (unknown), (unknown), Nancy A. Thornberry, (unknown), Robert Zamboni, Sophie Roy, Donald W. Nicholson	673
12	Caspase‐mediated proteolysis during apoptosis: insights from apoptotic neutrophils 1998 ·FEBS Letters ·Darshak Sanghavi, Marcus Thelen, Nancy A. Thornberry, Livia Casciola‐Rosen, Antony Rosen	78
13	Definition and Redesign of the Extended Substrate Specificity of Granzyme B 1998 ·Journal of Biological Chemistry ·Jennifer L. Harris, Erin P. Peterson, Dorothy Hudig, Nancy A. Thornberry, Charles S. Craik	159
14	Caspases Cleave Focal Adhesion Kinase during Apoptosis to Generate a FRNK-like Polypeptide 1998 ·Journal of Biological Chemistry ·François G. Gervais, Nancy A. Thornberry, (unknown), Donald W. Nicholson, Sophie Roy	175
15	A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B breakdown → 1997 ·Journal of Biological Chemistry ·Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson, Dita Rasper, (unknown), Margarita García‐Calvo, (unknown), (unknown), Sophie Roy, John P. Vaillancourt, Kevin T. Chapman, Donald W. Nicholson	1802
16	Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract 1996 ·Nature Genetics ·Y. Paul Goldberg, Donald W. Nicholson, Dita Rasper, Michael A. Kalchman, Hiroshi Koide, Rona K. Graham, (unknown), Parsa Kazemi‐Esfarjani, Nancy A. Thornberry, (unknown), Michael R. Hayden	465
17	Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. breakdown → 1996 ·The Journal of Experimental Medicine ·Livia Casciola‐Rosen, Donald W. Nicholson, T Chong, Kevin Rowan, Nancy A. Thornberry, Douglas K. Miller, Antony Rosen	563
18	A Synthetic Inhibitor of Interleukin-lβ Converting Enzyme Prevents Endotoxin-Induced Interleukin-lβ Production In Vitro and In Vivo 1995 ·Journal of Interferon & Cytokine Research ·D. Fletcher, (unknown), (unknown), Jayne Chin, Linda A. Egger, G Limjuco, Silvi Luell, D. Euan MacIntyre, Erin P. Peterson, Nancy A. Thornberry, Matthew J. Kostura	35
19	Interleukin‐1βconverting enzyme: A novel cysteine protease required for IL‐1β production and implicated in programmed cell death 1995 ·Protein Science ·Nancy A. Thornberry, Susan M. Molineaux	140
20	[43] Interleukin-1β converting enzyme 1994 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Nancy A. Thornberry	182

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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