Blair R. Leavitt

31.3k total citations · 13 hit papers
230 papers, 20.9k citations indexed

About

Blair R. Leavitt is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Neurology. According to data from OpenAlex, Blair R. Leavitt has authored 230 papers receiving a total of 20.9k indexed citations (citations by other indexed papers that have themselves been cited), including 182 papers in Cellular and Molecular Neuroscience, 137 papers in Molecular Biology and 104 papers in Neurology. Recurrent topics in Blair R. Leavitt's work include Genetic Neurodegenerative Diseases (170 papers), Mitochondrial Function and Pathology (104 papers) and Neurological disorders and treatments (78 papers). Blair R. Leavitt is often cited by papers focused on Genetic Neurodegenerative Diseases (170 papers), Mitochondrial Function and Pathology (104 papers) and Neurological disorders and treatments (78 papers). Blair R. Leavitt collaborates with scholars based in Canada, United States and United Kingdom. Blair R. Leavitt's co-authors include Michael R. Hayden, Sarah J. Tabrizi, Rachael I. Scahill, Jeffrey D. Macklis, Sanjay S. P. Magavi, Ralf Reilmann, Douglas R. Langbehn, Alexandra Dürr, Julie C. Stout and Raymund A.C. Roos and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Blair R. Leavitt

220 papers receiving 20.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Huntington disease

2015 1.1k citations Michael R. Hayden, Blair R. Leavitt et al. profile →
Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

2001 1.0k citations Blair R. Leavitt, Michael R. Hayden et al. profile →
Induction of neurogenesis in the neocortex of adult mice

2000 980 citations Blair R. Leavitt et al. Nature profile →
The current landscape of nucleic acid therapeutics

2021 934 citations Jayesh A. Kulkarni, Dominik Witzigmann et al. Nature Nanotechnology profile →
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines

2002 821 citations Blair R. Leavitt, Michael R. Hayden et al. profile →
Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data

2009 756 citations Sarah J. Tabrizi, Douglas R. Langbehn et al. profile →
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

2003 720 citations Blair R. Leavitt, Michael R. Hayden et al. profile →
Huntington disease: natural history, biomarkers and prospects for therapeutics

2014 705 citations Edward J. Wild, Douglas R. Langbehn et al. profile →
A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration

1999 669 citations John Hodgson, Blair R. Leavitt et al. profile →
Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data

2013 622 citations Sarah J. Tabrizi, Rachael I. Scahill et al. profile →
Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

2006 505 citations Ge Lu, Blair R. Leavitt et al. profile →
Potential disease-modifying therapies for Huntington's disease: lessons learned and future opportunities

2022 190 citations Sarah J. Tabrizi, Carlos Estevez‐Fraga et al. profile →
Lipid-Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Components

2022 178 citations Sarah B. Thomson, Blair R. Leavitt et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Blair R. Leavitt Canada	70	14.4k	13.5k	7.5k	1.4k	1.4k	230	20.9k
Steven Finkbeiner United States	58	10.3k 0.7×	10.8k 0.8×	4.2k 0.6×	2.2k 1.5×	3.3k 2.3×	140	18.9k
Marian DiFiglia United States	63	13.2k 0.9×	12.8k 0.9×	5.2k 0.7×	885 0.6×	1.4k 1.0×	156	18.4k
Robert J. Ferrante United States	85	13.0k 0.9×	14.3k 1.1×	9.8k 1.3×	3.1k 2.2×	3.8k 2.7×	160	26.2k
Anne B. Young United States	69	14.9k 1.0×	8.9k 0.7×	7.1k 0.9×	1.5k 1.0×	1.9k 1.3×	167	20.4k
Marcy E. MacDonald United States	68	16.1k 1.1×	16.0k 1.2×	7.1k 0.9×	831 0.6×	1.9k 1.3×	183	22.2k
Elena Cattaneo Italy	66	9.8k 0.7×	12.7k 0.9×	3.1k 0.4×	1.2k 0.8×	2.0k 1.4×	218	19.2k
Philippe Hantraye France	61	7.0k 0.5×	5.7k 0.4×	3.7k 0.5×	1.4k 1.0×	1.7k 1.2×	199	12.5k
Gillian P. Bates United Kingdom	80	20.2k 1.4×	21.3k 1.6×	7.7k 1.0×	1.1k 0.8×	2.2k 1.6×	233	28.4k
Sarah J. Tabrizi United Kingdom	80	15.4k 1.1×	13.1k 1.0×	9.9k 1.3×	2.5k 1.7×	2.1k 1.5×	379	23.1k
Deniz Kirik Sweden	65	9.6k 0.7×	5.3k 0.4×	6.8k 0.9×	2.0k 1.4×	1.5k 1.1×	170	15.6k

Countries citing papers authored by Blair R. Leavitt

Since Specialization

Citations

This map shows the geographic impact of Blair R. Leavitt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Blair R. Leavitt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Blair R. Leavitt more than expected).

Fields of papers citing papers by Blair R. Leavitt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Blair R. Leavitt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Blair R. Leavitt. The network helps show where Blair R. Leavitt may publish in the future.

Co-authorship network of co-authors of Blair R. Leavitt

This figure shows the co-authorship network connecting the top 25 collaborators of Blair R. Leavitt. A scholar is included among the top collaborators of Blair R. Leavitt based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Blair R. Leavitt. Blair R. Leavitt is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Frank, Samuel, Jody Goldstein, Elise Kayson, et al.. (2025). Safety and Efficacy of Deutetrabenazine at High versus Lower Daily Dosages in the ARC-HD Study to Treat Chorea in Huntington Disease. CNS Drugs. 39(2). 185–195. 1 indexed citations

Estevez‐Fraga, Carlos, Justine Y. Hansen, Paul Zeun, et al.. (2025). Cell-specific mechanisms drive connectivity across the time course of Huntington’s disease. Nature Communications. 16(1). 5519–5519.

Thomson, Sarah B., et al.. (2024). Restricting lysine normalizes toxic catabolites associated with ALDH7A1 deficiency in cells and mice. Cell Reports. 43(12). 115069–115069. 6 indexed citations

Caron, Nicholas S., Lauren M. Byrne, Jeffrey N. Bone, et al.. (2024). Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington’s disease mice. Translational Neurodegeneration. 13(1). 50–50.

Estevez‐Fraga, Carlos, André Altmann, Christopher S. Parker, et al.. (2023). Genetic topography and cortical cell loss in Huntington's disease link development and neurodegeneration. Brain. 146(11). 4532–4546. 18 indexed citations

Caron, Nicholas S., Arsalan S. Haqqani, Amirah E.-E. Aly, et al.. (2022). Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity. Brain Communications. 4(6). fcac309–fcac309. 16 indexed citations

Kulkarni, Jayesh A., Dominik Witzigmann, Sarah B. Thomson, et al.. (2021). Author Correction: The current landscape of nucleic acid therapeutics. Nature Nanotechnology. 16(7). 841–841. 16 indexed citations

Galván, Adriana, Terri L. Petkau, Austin Hill, et al.. (2021). Intracerebroventricular Administration of AAV9-PHP.B SYN1-EmGFP Induces Widespread Transgene Expression in the Mouse and Monkey Central Nervous System. Human Gene Therapy. 32(11-12). 599–615. 22 indexed citations

Estevez‐Fraga, Carlos, Rachael I. Scahill, Alexandra Dürr, et al.. (2021). Composite UHDRS Correlates With Progression of Imaging Biomarkers in Huntington's Disease. Movement Disorders. 36(5). 1259–1264. 17 indexed citations

10.

Kulkarni, Jayesh A., Dominik Witzigmann, Sarah B. Thomson, et al.. (2021). The current landscape of nucleic acid therapeutics. Nature Nanotechnology. 16(6). 630–643. 934 indexed citations breakdown →

11.

Andrews, Sophie C., Douglas R. Langbehn, David Craufurd, et al.. (2020). Apathy predicts rate of cognitive decline over 24 months in premanifest Huntington's disease. Psychological Medicine. 51(8). 1338–1344. 26 indexed citations

12.

Kulkarni, Jayesh A., Sarah B. Thomson, Josh Zaifman, et al.. (2020). Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles. Nanoscale. 12(47). 23959–23966. 49 indexed citations

13.

Ciosi, Marc, Alastair Maxwell, Sarah A. Cumming, et al.. (2019). A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes. EBioMedicine. 48. 568–580. 101 indexed citations

14.

Minkova, Lora, Sarah Gregory, Rachael I. Scahill, et al.. (2017). Cross-sectional and longitudinal voxel-based grey matter asymmetries in Huntington's disease. NeuroImage Clinical. 17. 312–324. 24 indexed citations

15.

Fotovati, Abbas, Loic P. Deleyrolle, Cathy Lee, et al.. (2011). YB-1 Bridges Neural Stem Cells and Brain Tumor–Initiating Cells via Its Roles in Differentiation and Cell Growth. Cancer Research. 71(16). 5569–5578. 69 indexed citations

16.

Yeretssian, Garabet, Karine Doiron, Wei Shao, et al.. (2009). Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection. Proceedings of the National Academy of Sciences. 106(22). 9016–9020. 48 indexed citations

17.

Clark, Andrea L., Hao Li, Garnette R. Sutherland, et al.. (2004). Canadian Association of Neuropathologists Abstracts of papers and cases presented at the 44th Annual Meeting. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 31(4). 586–591. 1 indexed citations

18.

Hagerman, Randi J., Blair R. Leavitt, F. Farzin, et al.. (2004). Fragile-X–Associated Tremor/Ataxia Syndrome (FXTAS) in Females with the FMR1 Premutation. The American Journal of Human Genetics. 74(5). 1051–1056. 238 indexed citations

19.

Leavitt, Blair R., Julian A. Guttman, John Hodgson, et al.. (2001). Wild-Type Huntingtin Reduces the Cellular Toxicity of Mutant Huntingtin In Vivo. The American Journal of Human Genetics. 68(2). 313–324. 179 indexed citations

20.

Clarke, G., Richard A. Collins, Blair R. Leavitt, et al.. (2001). addendum: A one-hit model of cell death in inherited neuronal degenerations. Nature. 409(6819). 542–542. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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