Richard I. Morimoto

57.8k total citations · 21 hit papers
285 papers, 43.8k citations indexed

About

Richard I. Morimoto is a scholar working on Molecular Biology, Cell Biology and Aging. According to data from OpenAlex, Richard I. Morimoto has authored 285 papers receiving a total of 43.8k indexed citations (citations by other indexed papers that have themselves been cited), including 235 papers in Molecular Biology, 81 papers in Cell Biology and 67 papers in Aging. Recurrent topics in Richard I. Morimoto's work include Heat shock proteins research (157 papers), Endoplasmic Reticulum Stress and Disease (76 papers) and Genetics, Aging, and Longevity in Model Organisms (67 papers). Richard I. Morimoto is often cited by papers focused on Heat shock proteins research (157 papers), Endoplasmic Reticulum Stress and Disease (76 papers) and Genetics, Aging, and Longevity in Model Organisms (67 papers). Richard I. Morimoto collaborates with scholars based in United States, United Kingdom and Germany. Richard I. Morimoto's co-authors include Lea Sistonen, Dick D. Mosser, Johnathan Labbadia, Kevin D. Sarge, William E. Balch, Jeffery W. Kelly, Andrew Dillin, A. Tissières, Costa Georgopoulos and James F. Morley and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Richard I. Morimoto

285 papers receiving 42.9k citations

Hit Papers

Adapting Proteostasis for... 1990 2026 2002 2014 2008 2014 2000 1993 1994 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Adapting Proteostasis for Disease Intervention
    2008 1.9k citations William E. Balch, Richard I. Morimoto et al. Science profile →
  2. Geroscience: Linking Aging to Chronic Disease
    2014 1.7k citations Ana María Cuervo, Richard I. Morimoto et al. profile →
  3. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
    2000 1.3k citations Richard I. Morimoto et al. profile →
  4. Cells in Stress: Transcriptional Activation of Heat Shock Genes
    1993 1.2k citations Richard I. Morimoto Science profile →
  5. The Biology of heat shock proteins and molecular chaperones.
    1994 1.1k citations Richard I. Morimoto et al. profile →
  6. Heat shock factors: integrators of cell stress, development and lifespan
    2010 1.1k citations Richard I. Morimoto et al. profile →
  7. The Biology of Proteostasis in Aging and Disease
    2015 1000 citations Richard I. Morimoto et al. profile →
  8. Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
    2009 895 citations Richard I. Morimoto, Jeffery W. Kelly et al. profile →
  9. Autophagy in healthy aging and disease
    2021 798 citations Richard I. Morimoto et al. profile →
  10. Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.
    1993 746 citations Kevin D. Sarge, Shawn P. Murphy et al. Molecular and Cellular Biology profile →
  11. Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
    2008 714 citations Richard I. Morimoto profile →
  12. The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
    2002 629 citations Heather R. Brignull, Richard I. Morimoto et al. Proceedings of the National Academy of Sciences profile →
  13. Stress proteins in biology and medicine
    1990 627 citations Richard I. Morimoto et al. profile →
  14. The Chaperone Function of hsp70 Is Required for Protection against Stress-Induced Apoptosis
    2000 597 citations Richard I. Morimoto et al. Molecular and Cellular Biology profile →
  15. Regulation of Longevity inCaenorhabditis elegansby Heat Shock Factor and Molecular Chaperones
    2003 583 citations Richard I. Morimoto et al. profile →
  16. Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1
    2009 581 citations Richard I. Morimoto et al. Science profile →
  17. Chaperoning signaling pathways: molecular chaperones as stress-sensing`heat shock' proteins
    2002 535 citations Ellen A. A. Nollen, Richard I. Morimoto profile →
  18. Stress–inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection
    1998 528 citations Richard I. Morimoto et al. profile →
  19. Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
    2009 516 citations Anat Ben‐Zvi, Elizabeth A. Miller et al. Proceedings of the National Academy of Sciences profile →
  20. Progressive Disruption of Cellular Protein Folding in Models of Polyglutamine Diseases
    2006 513 citations Tali Gidalevitz, Anat Ben‐Zvi et al. Science profile →
  21. Molecularchaperones as HSF1-specific transcriptional repressors
    1998 506 citations Richard I. Morimoto et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Richard I. Morimoto United States 109 33.3k 10.5k 8.0k 6.8k 4.8k 285 43.8k
Susan Lindquist United States 125 44.9k 1.3× 8.1k 0.8× 3.3k 0.4× 7.3k 1.1× 3.5k 0.7× 301 56.5k
F. Ulrich Hartl Germany 122 45.6k 1.4× 10.0k 0.9× 2.0k 0.3× 4.0k 0.6× 2.6k 0.5× 284 53.2k
Bernd Bukau Germany 107 30.3k 0.9× 6.6k 0.6× 1.2k 0.1× 1.5k 0.2× 2.2k 0.5× 259 34.5k
Johannes Büchner Germany 91 25.7k 0.8× 4.7k 0.5× 908 0.1× 2.0k 0.3× 2.2k 0.5× 293 29.8k
Alfred L. Goldberg United States 138 49.6k 1.5× 17.3k 1.7× 1.4k 0.2× 11.9k 1.8× 402 0.1× 369 67.3k
Martin D. Brand United Kingdom 97 23.4k 0.7× 3.3k 0.3× 1.6k 0.2× 15.2k 2.2× 190 0.0× 365 37.1k
Nikki J. Holbrook United States 72 15.3k 0.5× 4.0k 0.4× 1.3k 0.2× 4.0k 0.6× 288 0.1× 154 29.2k
John R. Yates United States 161 78.4k 2.4× 17.4k 1.7× 2.6k 0.3× 6.2k 0.9× 152 0.0× 995 108.9k
Eisuke Nishida Japan 104 26.9k 0.8× 9.9k 0.9× 1.9k 0.2× 2.2k 0.3× 177 0.0× 332 37.5k
Paul Tempst United States 143 62.1k 1.9× 8.7k 0.8× 851 0.1× 7.7k 1.1× 207 0.0× 320 80.8k

Countries citing papers authored by Richard I. Morimoto

Since Specialization
Citations

This map shows the geographic impact of Richard I. Morimoto's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard I. Morimoto with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard I. Morimoto more than expected).

Fields of papers citing papers by Richard I. Morimoto

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard I. Morimoto. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard I. Morimoto. The network helps show where Richard I. Morimoto may publish in the future.

Co-authorship network of co-authors of Richard I. Morimoto

This figure shows the co-authorship network connecting the top 25 collaborators of Richard I. Morimoto. A scholar is included among the top collaborators of Richard I. Morimoto based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Richard I. Morimoto. Richard I. Morimoto is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Weerawarna, Pathum M., Isaac T. Schiefer, Pedro Soares, et al.. (2023). Target Identification of a Class of Pyrazolone Protein Aggregation Inhibitor Therapeutics for Amyotrophic Lateral Sclerosis. ACS Central Science. 10(1). 87–103. 2 indexed citations
2.
Sato, Chihiro, Elena Ficulle, Anan Yu, et al.. (2021). Recapitulation of Endogenous 4R Tau Expression and Formation of Insoluble Tau in Directly Reprogrammed Human Neurons. SSRN Electronic Journal. 5 indexed citations
3.
Omori, Hiroko, Maho Hamasaki, Tomohisa Hatta, et al.. (2020). ERdj8 governs the size of autophagosomes during the formation process. The Journal of Cell Biology. 219(8). 21 indexed citations
4.
Yu, Anan, Susan G. Fox, Annalisa Cavallini, et al.. (2019). Tau protein aggregates inhibit the protein-folding and vesicular trafficking arms of the cellular proteostasis network. Journal of Biological Chemistry. 294(19). 7917–7930. 42 indexed citations
5.
Sala, Ambre J., Laura C. Bott, & Richard I. Morimoto. (2017). Shaping proteostasis at the cellular, tissue, and organismal level. The Journal of Cell Biology. 216(5). 1231–1241. 178 indexed citations
6.
Kirstein, Janine, Daisuke Morito, Taichi Kakihana, et al.. (2015). Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments. The EMBO Journal. 34(18). 2334–2349. 73 indexed citations
7.
Balch, William E., Jacob I. Sznajder, Daniel Finley, et al.. (2013). Malfolded Protein Structure and Proteostasis in Lung Diseases. American Journal of Respiratory and Critical Care Medicine. 189(1). 96–103. 44 indexed citations
8.
Ciryam, Prajwal, Gian Gaetano Tartaglia, Richard I. Morimoto, Christopher M. Dobson, & Michele Vendruscolo. (2013). Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins. Cell Reports. 5(3). 781–790. 224 indexed citations
9.
Morimoto, Richard I., Dennis J. Selkoe, & Jeffery W. Kelly. (2012). Protein homeostasis : a subject collection from Cold Spring Harbor Perspectives in biology. 1 indexed citations
10.
Rampelt, Heike, Janine Kirstein, Nadinath B. Nillegoda, et al.. (2012). Metazoan Hsp70 machines use Hsp110 to power protein disaggregation. The EMBO Journal. 31(21). 4221–4235. 236 indexed citations
11.
Prahlad, Veena & Richard I. Morimoto. (2011). Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins. Proceedings of the National Academy of Sciences. 108(34). 14204–14209. 120 indexed citations
12.
Ben‐Zvi, Anat, Elizabeth A. Miller, & Richard I. Morimoto. (2009). Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proceedings of the National Academy of Sciences. 106(35). 14914–14919. 516 indexed citations breakdown →
13.
Prahlad, Veena, et al.. (2008). Regulation of the Cellular Heat Shock Response in Caenorhabditis elegans by Thermosensory Neurons. Science. 320(5877). 811–814. 282 indexed citations
14.
Gidalevitz, Tali, et al.. (2006). Progressive Disruption of Cellular Protein Folding in Models of Polyglutamine Diseases. Science. 311(5766). 1471–1474. 513 indexed citations breakdown →
15.
Finkbeiner, Steven, Ana María Cuervo, Richard I. Morimoto, & Paul J. Muchowski. (2006). Disease-Modifying Pathways in Neurodegeneration. Journal of Neuroscience. 26(41). 10349–10357. 42 indexed citations
16.
Nollen, Ellen A. A., Susana M. D. A. Garcia, Gijs van Haaften, et al.. (2004). Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Proceedings of the National Academy of Sciences. 101(17). 6403–6408. 315 indexed citations
17.
Mathew, Anu, Sameer K. Mathur, & Richard I. Morimoto. (1998). Heat Shock Response and Protein Degradation: Regulation of HSF2 by the Ubiquitin-Proteasome Pathway. Molecular and Cellular Biology. 18(9). 5091–5098. 180 indexed citations
18.
Nakai, Akira, Yoshinori Kawazoe, Masako Tanabe, Kazuhiro Nagata, & Richard I. Morimoto. (1995). The DNA-Binding Properties of Two Heat Shock Factors, HSF1 and HSF3, Are Induced in the Avian Erythroblast Cell Line HD6. Molecular and Cellular Biology. 15(10). 5268–5278. 91 indexed citations
19.
Morimoto, Richard I., Donald A. Jurivich, Paul E. Kroeger, et al.. (1994). 17 Regulation of Heat Shock Gene Transcription by a Family of Heat Shock Factors. Cold Spring Harbor Monograph Archive. 26. 417–455. 21 indexed citations
20.
Kroeger, Paul E. & Richard I. Morimoto. (1994). Selection of New HSF1 and HSF2 DNA-Binding Sites Reveals Differences in Trimer Cooperativity. Molecular and Cellular Biology. 14(11). 7592–7603. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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