Paul J. Muchowski

11.1k total citations · 3 hit papers
68 papers, 8.3k citations indexed

About

Paul J. Muchowski is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Neurology. According to data from OpenAlex, Paul J. Muchowski has authored 68 papers receiving a total of 8.3k indexed citations (citations by other indexed papers that have themselves been cited), including 49 papers in Molecular Biology, 41 papers in Cellular and Molecular Neuroscience and 12 papers in Neurology. Recurrent topics in Paul J. Muchowski's work include Genetic Neurodegenerative Diseases (41 papers), Mitochondrial Function and Pathology (20 papers) and Heat shock proteins research (17 papers). Paul J. Muchowski is often cited by papers focused on Genetic Neurodegenerative Diseases (41 papers), Mitochondrial Function and Pathology (20 papers) and Heat shock proteins research (17 papers). Paul J. Muchowski collaborates with scholars based in United States, United Kingdom and Germany. Paul J. Muchowski's co-authors include Jennifer L. Wacker, Robert Schwarcz, Hui‐Qiu Wu, John P. Bruno, John I. Clark, Flaviano Giorgini, Susan Lindquist, Justin Legleiter, Erich E. Wanker and Martin L. Duennwald and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Paul J. Muchowski

67 papers receiving 8.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Kynurenines in the mammalian brain: when physiology meets pathology

2012 1.1k citations Robert Schwarcz, John P. Bruno et al. Nature reviews. Neuroscience profile →
Modulation of neurodegeneration by molecular chaperones

2004 804 citations Paul J. Muchowski, Jennifer L. Wacker Nature reviews. Neuroscience profile →
Hsp70 and Hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

2000 523 citations Paul J. Muchowski, Erich E. Wanker et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Paul J. Muchowski United States	45	5.3k	3.1k	1.6k	1.5k	1.2k	68	8.3k
Hiroyuki Nawa Japan	62	6.2k 1.2×	8.5k 2.8×	1.1k 0.7×	1.4k 0.9×	645 0.5×	185	13.4k
Tsung‐Ping Su United States	56	8.9k 1.7×	5.2k 1.7×	1.4k 0.9×	846 0.6×	991 0.8×	132	11.4k
Fabrizio Gardoni Italy	53	3.0k 0.6×	4.7k 1.5×	516 0.3×	2.0k 1.3×	508 0.4×	150	8.6k
Takeshi Tabira Japan	52	3.3k 0.6×	1.7k 0.5×	527 0.3×	3.5k 2.4×	797 0.7×	257	9.9k
Stephen D. Ginsberg United States	59	4.2k 0.8×	2.8k 0.9×	608 0.4×	4.4k 3.0×	838 0.7×	184	10.3k
Robert Nitsch Germany	61	5.4k 1.0×	3.8k 1.2×	541 0.3×	1.4k 1.0×	860 0.7×	176	13.1k
Pyung‐Lim Han South Korea	47	3.3k 0.6×	2.0k 0.6×	661 0.4×	1.2k 0.8×	468 0.4×	141	7.1k
Bastian Hengerer Germany	39	2.5k 0.5×	3.7k 1.2×	464 0.3×	1.4k 1.0×	391 0.3×	107	7.2k
Giambattista Bonanno Italy	45	3.1k 0.6×	3.4k 1.1×	489 0.3×	685 0.5×	330 0.3×	204	6.8k
Robert O. Messing United States	58	5.2k 1.0×	4.9k 1.6×	289 0.2×	2.1k 1.4×	638 0.5×	177	10.7k

Countries citing papers authored by Paul J. Muchowski

Since Specialization

Citations

This map shows the geographic impact of Paul J. Muchowski's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul J. Muchowski with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul J. Muchowski more than expected).

Fields of papers citing papers by Paul J. Muchowski

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul J. Muchowski. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul J. Muchowski. The network helps show where Paul J. Muchowski may publish in the future.

Co-authorship network of co-authors of Paul J. Muchowski

This figure shows the co-authorship network connecting the top 25 collaborators of Paul J. Muchowski. A scholar is included among the top collaborators of Paul J. Muchowski based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul J. Muchowski. Paul J. Muchowski is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Michael, et al.. (2024). Effects of a cannabidiol/terpene formulation on sleep in individuals with insomnia: a double-blind, placebo-controlled, randomized, crossover study. Journal of Clinical Sleep Medicine. 21(1). 69–80. 2 indexed citations

Kwan, Wanda, Anna Magnusson, Austin Chou, et al.. (2012). Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease. Journal of Neuroscience. 32(1). 133–142. 60 indexed citations

Kwan, Wanda, Ulrike Träger, Dimitrios Davalos, et al.. (2012). Mutant huntingtin impairs immune cell migration in Huntington disease. Journal of Clinical Investigation. 122(12). 4737–4747. 114 indexed citations

Sontag, Emily M., Gregor P. Lotz, Namita Agrawal, et al.. (2012). Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models. Journal of Neuroscience. 32(32). 11109–11119. 78 indexed citations

Sancenón, Vicente, Christina Patrick, Janice Griffith, et al.. (2012). Suppression of α-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context. Human Molecular Genetics. 21(11). 2432–2449. 52 indexed citations

Green, Edward W., Susanna Campesan, Carlo Breda, et al.. (2012). Drosophila eye color mutants as therapeutic tools for Huntington disease. Fly. 6(2). 117–120. 30 indexed citations

Sontag, Emily M., Gregor P. Lotz, Guocheng Yang, et al.. (2012). Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules. Journal of Huntington s Disease. 1(1). 119–132. 24 indexed citations

Schwarcz, Robert, John P. Bruno, Paul J. Muchowski, & Hui‐Qiu Wu. (2012). Kynurenines in the mammalian brain: when physiology meets pathology. Nature reviews. Neuroscience. 13(7). 465–477. 1145 indexed citations breakdown →

Muchowski, Paul J., et al.. (2012). Genetic Deficiency of Complement Component 3 does not Alter Disease Progression in a Mouse Model of Huntington's Disease. Journal of Huntington s Disease. 1(1). 107–118. 18 indexed citations

10.

Chen, Xuesong, Jun Wu, Yuan Luo, et al.. (2011). Expanded Polyglutamine-Binding Peptoid as a Novel Therapeutic Agent for Treatment of Huntington's Disease. Chemistry & Biology. 18(9). 1113–1125. 39 indexed citations

11.

Sathyasaikumar, Korrapati V., et al.. (2010). Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington’s disease. Journal of Neurochemistry. 113(6). 1416–1425. 58 indexed citations

12.

Legleiter, Justin, Gregor P. Lotz, Ellen Sapp, et al.. (2010). Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo. Journal of Biological Chemistry. 285(19). 14777–14790. 176 indexed citations

13.

Schwarcz, Robert, et al.. (2010). Targeting Kynurenine 3-Monooxygenase (KMO): Implications for Therapy in Huntingtons Disease. CNS & Neurological Disorders - Drug Targets. 9(6). 791–800. 68 indexed citations

14.

Wacker, Jennifer L., San‐Yuan Huang, Andrew D. Steele, et al.. (2009). Loss of Hsp70 Exacerbates Pathogenesis But Not Levels of Fibrillar Aggregates in a Mouse Model of Huntington's Disease. Journal of Neuroscience. 29(28). 9104–9114. 90 indexed citations

15.

Giorgini, Flaviano, Thomas Möller, Wanda Kwan, et al.. (2007). Histone Deacetylase Inhibition Modulates Kynurenine Pathway Activation in Yeast, Microglia, and Mice Expressing a Mutant Huntingtin Fragment. Journal of Biological Chemistry. 283(12). 7390–7400. 80 indexed citations

16.

Finkbeiner, Steven, Ana María Cuervo, Richard I. Morimoto, & Paul J. Muchowski. (2006). Disease-Modifying Pathways in Neurodegeneration. Journal of Neuroscience. 26(41). 10349–10357. 42 indexed citations

17.

Ehrnhoefer, Dagmar E., Martin L. Duennwald, Jennifer L. Wacker, et al.. (2006). Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Human Molecular Genetics. 15(18). 2743–2751. 332 indexed citations

18.

Derham, Barry K., Martinus A.M. van Boekel, Paul J. Muchowski, et al.. (2001). Chaperone function of mutant versions of αA‐ and αB‐crystallin prepared to pinpoint chaperone binding sites. European Journal of Biochemistry. 268(3). 713–721. 55 indexed citations

19.

Clark, John I. & Paul J. Muchowski. (2000). Small heat-shock proteins and their potential role in human disease. Current Opinion in Structural Biology. 10(1). 52–59. 193 indexed citations

20.

Muchowski, Paul J., et al.. (1999). Site-directed mutations within the core “α-crystallin” domain of the small heat-shock protein, human αB-crystallin, decrease molecular chaperone functions. Journal of Molecular Biology. 289(2). 397–411. 81 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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