William E. Balch

33.1k total citations · 6 hit papers
230 papers, 25.4k citations indexed

About

William E. Balch is a scholar working on Cell Biology, Molecular Biology and Physiology. According to data from OpenAlex, William E. Balch has authored 230 papers receiving a total of 25.4k indexed citations (citations by other indexed papers that have themselves been cited), including 163 papers in Cell Biology, 135 papers in Molecular Biology and 39 papers in Physiology. Recurrent topics in William E. Balch's work include Cellular transport and secretion (135 papers), Endoplasmic Reticulum Stress and Disease (70 papers) and Lipid Membrane Structure and Behavior (31 papers). William E. Balch is often cited by papers focused on Cellular transport and secretion (135 papers), Endoplasmic Reticulum Stress and Disease (70 papers) and Lipid Membrane Structure and Behavior (31 papers). William E. Balch collaborates with scholars based in United States, Canada and Switzerland. William E. Balch's co-authors include Jeffery W. Kelly, Richard I. Morimoto, Andrew Dillin, Helen Plutner, Meir Aridor, Atanas V. Koulov, James E. Rothman, Douglas M. Fowler, Claude Nuoffer and Sergei I. Bannykh and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

William E. Balch

226 papers receiving 24.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Adapting Proteostasis for Disease Intervention

2008 1.9k citations William E. Balch, Richard I. Morimoto et al. profile →
Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

2009 895 citations Richard I. Morimoto, Jeffery W. Kelly et al. profile →
Functional amyloid – from bacteria to humans

2007 880 citations Atanas V. Koulov, William E. Balch et al. profile →
Functional Amyloid Formation within Mammalian Tissue

2005 680 citations Atanas V. Koulov, William E. Balch et al. profile →
Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

1984 579 citations William E. Balch et al. Cell profile →
From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

2016 422 citations Guido Veit, Radu G. Avramescu et al. Molecular Biology of the Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William E. Balch United States	87	16.9k	14.0k	4.6k	2.1k	1.9k	230	25.4k
Marilyn G. Farquhar United States	88	15.7k 0.9×	8.8k 0.6×	3.6k 0.8×	2.7k 1.3×	1.0k 0.5×	205	28.2k
Frederick R. Maxfield United States	95	17.5k 1.0×	9.6k 0.7×	5.4k 1.2×	4.0k 1.9×	845 0.4×	261	29.3k
Wanjin Hong Singapore	81	12.5k 0.7×	11.7k 0.8×	2.1k 0.4×	1.8k 0.9×	607 0.3×	323	20.9k
Richard G.W. Anderson United States	98	26.5k 1.6×	18.4k 1.3×	6.8k 1.5×	4.9k 2.3×	1.1k 0.6×	176	39.0k
Ron R. Kopito United States	67	14.6k 0.9×	7.3k 0.5×	3.6k 0.8×	1.0k 0.5×	2.1k 1.1×	136	22.6k
Peter J. Parker United Kingdom	95	25.3k 1.5×	7.6k 0.5×	3.0k 0.7×	1.5k 0.7×	753 0.4×	406	33.7k
Richard D. Klausner United States	116	22.1k 1.3×	8.0k 0.6×	2.4k 0.5×	1.7k 0.8×	1.6k 0.8×	243	37.7k
Channing J. Der United States	111	36.2k 2.1×	10.6k 0.8×	2.0k 0.4×	1.9k 0.9×	2.3k 1.2×	406	48.3k
Brian A. Hemmings Switzerland	102	33.2k 2.0×	7.2k 0.5×	3.0k 0.7×	2.4k 1.1×	1.2k 0.6×	313	42.4k
Michael N. Hall Switzerland	108	34.3k 2.0×	6.7k 0.5×	3.9k 0.8×	2.4k 1.1×	1.3k 0.7×	246	44.9k

Countries citing papers authored by William E. Balch

Since Specialization

Citations

This map shows the geographic impact of William E. Balch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William E. Balch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William E. Balch more than expected).

Fields of papers citing papers by William E. Balch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William E. Balch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William E. Balch. The network helps show where William E. Balch may publish in the future.

Co-authorship network of co-authors of William E. Balch

This figure shows the co-authorship network connecting the top 25 collaborators of William E. Balch. A scholar is included among the top collaborators of William E. Balch based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William E. Balch. William E. Balch is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Chao, et al.. (2025). Spatial covariance reveals isothiocyanate natural products adjust redox stress to restore function in alpha-1-antitrypsin deficiency. Cell Reports Medicine. 6(1). 101917–101917.

Wang, Chao, et al.. (2024). Tracing genetic diversity captures the molecular basis of misfolding disease. Nature Communications. 15(1). 3333–3333. 3 indexed citations

Stoeger, Thomas, Rogan A. Grant, Alexandra C. McQuattie‐Pimentel, et al.. (2022). Aging is associated with a systemic length-associated transcriptome imbalance. Nature Aging. 2(12). 1191–1206. 61 indexed citations

Pottekat, Anita, Saiful A. Mir, Salvatore Loguercio, et al.. (2020). Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding. Diabetes. 69(8). 1723–1734. 18 indexed citations

Wang, Chao, Pei Zhao, Darren M. Hutt, et al.. (2019). Individualized management of genetic diversity in Niemann-Pick C1 through modulation of the Hsp70 chaperone system. Human Molecular Genetics. 29(1). 1–19. 18 indexed citations

Bagdány, Miklós, Guido Veit, Ryosuke Fukuda, et al.. (2017). Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell. Nature Communications. 8(1). 398–398. 53 indexed citations

Thannickal, Victor J., M.R. Ven Murthy, William E. Balch, et al.. (2015). Blue Journal Conference. Aging and Susceptibility to Lung Disease. American Journal of Respiratory and Critical Care Medicine. 191(3). 261–269. 124 indexed citations

Balch, William E., Jacob I. Sznajder, Daniel Finley, et al.. (2013). Malfolded Protein Structure and Proteostasis in Lung Diseases. American Journal of Respiratory and Critical Care Medicine. 189(1). 96–103. 44 indexed citations

Hulleman, John D., Shalesh Kaushal, William E. Balch, & Jeffery W. Kelly. (2011). Compromised mutant EFEMP1 secretion associated with macular dystrophy remedied by proteostasis network alteration. Molecular Biology of the Cell. 22(24). 4765–4775. 31 indexed citations

10.

Wang, Xiaodong, Atanas V. Koulov, Wendy A. Kellner, John R. Riordan, & William E. Balch. (2008). Chemical and Biological Folding Contribute to Temperature‐Sensitive ΔF508 CFTR Trafficking. Traffic. 9(11). 1878–1893. 74 indexed citations

11.

Mu, Ting‐Wei, Derrick Sek Tong Ong, Yajuan Wang, et al.. (2008). Chemical and Biological Approaches Synergize to Ameliorate Protein-Folding Diseases. Cell. 134(5). 769–781. 313 indexed citations

12.

Wang, Xiaodong, John D. Venable, Paul LaPointe, et al.. (2006). Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis. Cell. 127(4). 803–815. 493 indexed citations

13.

LaPointe, Paul & William E. Balch. (2005). Purification and Properties of Mammalian Sec23/24 from Insect Cells. Methods in enzymology on CD-ROM/Methods in enzymology. 404. 66–74. 2 indexed citations

14.

Balch, William E., Channing J. Der, & Andrew G. Hall. (2005). GTPases regulating membrane dynamics. Elsevier eBooks. 1 indexed citations

15.

Alory, Christelle & William E. Balch. (2003). Molecular Evolution of the Rab-Escort-Protein/Guanine-Nucleotide-Dissociation-Inhibitor Superfamily. Molecular Biology of the Cell. 14(9). 3857–3867. 35 indexed citations

16.

Béraud-Dufour, Sophie & William E. Balch. (2001). [25] Structural and functional organization of ADP-ribosylation factor (ARF) proteins. Methods in enzymology on CD-ROM/Methods in enzymology. 329. 245–247. 7 indexed citations

17.

Weissman, Jacques T., Meir Aridor, & William E. Balch. (2001). [45] Purification and properties of rat liver Sec23–Sec24 complex. Methods in enzymology on CD-ROM/Methods in enzymology. 329. 431–438. 5 indexed citations

18.

Simpson, Jeremy C., Christiane Dascher, Lynne M. Roberts, Janet M. Lord, & William E. Balch. (1995). Ricin Cytotoxicity Is Sensitive to Recycling between the Endoplasmic Reticulum and the Golgi Complex. Journal of Biological Chemistry. 270(34). 20078–20083. 64 indexed citations

19.

Plutner, Helen, Adrienne D. Cox, S. Pind, et al.. (1991). Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.. The Journal of Cell Biology. 115(1). 31–43. 344 indexed citations

20.

Balch, William E.. (1990). Molecular dissection of early stages of the eukaryotic secretory pathway. Current Opinion in Cell Biology. 2(4). 634–641. 24 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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