Rachel C. Botham

556 total citations
15 papers, 430 citations indexed

About

Rachel C. Botham is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Rachel C. Botham has authored 15 papers receiving a total of 430 indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Molecular Biology, 4 papers in Organic Chemistry and 4 papers in Oncology. Recurrent topics in Rachel C. Botham's work include Cell death mechanisms and regulation (7 papers), PARP inhibition in cancer therapy (3 papers) and Carbohydrate Chemistry and Synthesis (2 papers). Rachel C. Botham is often cited by papers focused on Cell death mechanisms and regulation (7 papers), PARP inhibition in cancer therapy (3 papers) and Carbohydrate Chemistry and Synthesis (2 papers). Rachel C. Botham collaborates with scholars based in United States, Canada and United Kingdom. Rachel C. Botham's co-authors include Paul J. Hergenrother, Timothy M. Fan, Howard S. Roth, Diana C. West, Hua Wang, Bruce D. Hammock, Jeffery W. Kelly, K. Barry Sharpless, Suhua Li and Gencheng Li and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Scientific Reports.

In The Last Decade

Rachel C. Botham

15 papers receiving 420 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Rachel C. Botham United States	10	227	158	72	34	29	15	430
Chiara Borsari Switzerland	17	476 2.1×	292 1.8×	61 0.8×	31 0.9×	52 1.8×	40	729
Masahiro Shindo United States	5	152 0.7×	128 0.8×	54 0.8×	14 0.4×	41 1.4×	8	316
Richard Hernandez United States	9	220 1.0×	270 1.7×	121 1.7×	31 0.9×	26 0.9×	13	530
Federica Bucci Italy	14	428 1.9×	121 0.8×	168 2.3×	26 0.8×	21 0.7×	18	622
Roman N. Chuprov‐Netochin Russia	13	213 0.9×	51 0.3×	62 0.9×	12 0.4×	11 0.4×	34	386
Xiaolei Gao China	12	169 0.7×	89 0.6×	41 0.6×	4 0.1×	18 0.6×	31	365
Sung-Kee Chung South Korea	16	331 1.5×	211 1.3×	40 0.6×	10 0.3×	86 3.0×	24	547
Manish Solanki India	15	340 1.5×	136 0.9×	136 1.9×	7 0.2×	26 0.9×	32	585
Mária Bartošová Slovakia	7	205 0.9×	48 0.3×	42 0.6×	10 0.3×	13 0.4×	17	320
J. Miyazawa Japan	9	268 1.2×	75 0.5×	63 0.9×	9 0.3×	10 0.3×	21	445

Countries citing papers authored by Rachel C. Botham

Since Specialization

Citations

This map shows the geographic impact of Rachel C. Botham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rachel C. Botham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rachel C. Botham more than expected).

Fields of papers citing papers by Rachel C. Botham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rachel C. Botham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rachel C. Botham. The network helps show where Rachel C. Botham may publish in the future.

Co-authorship network of co-authors of Rachel C. Botham

This figure shows the co-authorship network connecting the top 25 collaborators of Rachel C. Botham. A scholar is included among the top collaborators of Rachel C. Botham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rachel C. Botham. Rachel C. Botham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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15 of 15 papers shown

Xiao, Qiang, Rachel C. Botham, Susan G. Fox, et al.. (2024). HaloTag as a substrate-based macroautophagy reporter. Proceedings of the National Academy of Sciences. 121(32). e2322500121–e2322500121. 3 indexed citations

Hallows, William C., Kristen J. Skvorak, Nicholas J. Agard, et al.. (2023). Optimizing human α-galactosidase for treatment of Fabry disease. Scientific Reports. 13(1). 4748–4748. 10 indexed citations

Dellas, Nikki, Joyce Liu, Rachel C. Botham, & Gjalt W. Huisman. (2021). Adapting protein sequences for optimized therapeutic efficacy. Current Opinion in Chemical Biology. 64. 38–47. 5 indexed citations

Huang, Shan, Rachel C. Botham, Gregory B. Daniel, et al.. (2021). Evaluation of a procaspase-3 activator with hydroxyurea or temozolomide against high-grade meningioma in cell culture and canine cancer patients. Neuro-Oncology. 23(10). 1723–1735. 8 indexed citations

Botham, Rachel C., William C. Hallows, Nikki Dellas, et al.. (2021). Engineering α-glucosidase to improve protein stability and cellular uptake for the potential treatment of Pompe disease. Molecular Genetics and Metabolism. 132(2). S20–S21. 1 indexed citations

Botham, Rachel C., Suhua Li, D.E. Mortenson, et al.. (2020). Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery. Nature Chemistry. 12(10). 906–913. 110 indexed citations

Joshi, Avadhut D., Rachel C. Botham, Howard S. Roth, et al.. (2017). Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant glioma patients. Oncotarget. 8(46). 80124–80138. 35 indexed citations

Botham, Rachel C., et al.. (2016). Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics. ACS Central Science. 2(8). 545–559. 28 indexed citations

Palchaudhuri, Rahul, Rachel C. Botham, Kathryn C. Partlow, et al.. (2015). A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed. Cell Reports. 13(9). 2027–2036. 77 indexed citations

10.

Roth, Howard S., et al.. (2015). Removal of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved Pharmacokinetics. Journal of Medicinal Chemistry. 58(9). 4046–4065. 18 indexed citations

11.

Botham, Rachel C., Timothy M. Fan, Isak Im, et al.. (2014). Dual Small-Molecule Targeting of Procaspase-3 Dramatically Enhances Zymogen Activation and Anticancer Activity. Journal of the American Chemical Society. 136(4). 1312–1319. 32 indexed citations

12.

Hsu, Danny, Howard S. Roth, Diana C. West, et al.. (2011). Parallel Synthesis and Biological Evaluation of 837 Analogues of Procaspase-Activating Compound 1 (PAC-1). ACS Combinatorial Science. 14(1). 44–50. 38 indexed citations

13.

Peterson, Quinn P., David R. Goode, Diana C. West, Rachel C. Botham, & Paul J. Hergenrother. (2010). Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis. Nature Protocols. 5(2). 294–302. 31 indexed citations

14.

Botham, Rachel C., Carine L. Collin, & Tia‐Lynn Ashman. (2009). Plant–Mycorrhizal Fungus Interactions Affect the Expression of Inbreeding Depression in Wild Strawberry. International Journal of Plant Sciences. 170(2). 143–150. 26 indexed citations

15.

Botham, Rachel C.. (1996). A study on the in vivo digestibility of retrograded starch. Carbohydrate Polymers. 29(4). 347–352. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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