Paul Tempst

101.7k total citations · 45 hit papers
320 papers, 80.8k citations indexed

About

Paul Tempst is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Paul Tempst has authored 320 papers receiving a total of 80.8k indexed citations (citations by other indexed papers that have themselves been cited), including 259 papers in Molecular Biology, 38 papers in Oncology and 34 papers in Cell Biology. Recurrent topics in Paul Tempst's work include Genomics and Chromatin Dynamics (54 papers), Epigenetics and DNA Methylation (48 papers) and RNA Research and Splicing (37 papers). Paul Tempst is often cited by papers focused on Genomics and Chromatin Dynamics (54 papers), Epigenetics and DNA Methylation (48 papers) and RNA Research and Splicing (37 papers). Paul Tempst collaborates with scholars based in United States, United Kingdom and Japan. Paul Tempst's co-authors include Hediye Erdjument‐Bromage, Yi Zhang, Danny Reinberg, Hengbin Wang, David M. Sabatini, Sankar Ghosh, Siraj M. Ali, Dos D. Sarbassov, Do‐Hyung Kim and Robert Latek and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Paul Tempst

316 papers receiving 79.4k citations

Hit Papers

Role of Histone H3 Lysine 27 Methylation in Polyco... 1985 2026 1998 2012 2002 1993 2002 2004 1994 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing
    2002 2.9k citations Ru Cao, Liangjun Wang et al. Science profile →
  2. SNAP receptors implicated in vesicle targeting and fusion
    1993 2.6k citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  3. mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
    2002 2.4k citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  4. Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton
    2004 2.1k citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  5. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    1994 1.9k citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  6. PRDM16 controls a brown fat/skeletal muscle switch
    2008 1.8k citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  7. Histone demethylation by a family of JmjC domain-containing proteins
    2005 1.7k citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  8. Role of histone H2A ubiquitination in Polycomb silencing
    2004 1.3k citations Hengbin Wang, Liangjun Wang et al. profile →
  9. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
    2011 1.3k citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  10. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
    2002 1.3k citations Andrei Kuzmichev, Hediye Erdjument‐Bromage et al. Genes & Development profile →
  11. RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
    1994 1.2k citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  12. Protein S-nitrosylation: a physiological signal for neuronal nitric oxide
    2001 1.2k citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  13. A cellular gene encodes scrapie PrP 27-30 protein
    1985 1.2k citations Stephen B. H. Kent, Paul Tempst et al. Cell profile →
  14. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
    2007 1.1k citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  15. Phosphorylation and Functional Inactivation of TSC2 by Erk
    2005 1.0k citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  16. Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B
    1998 909 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Science profile →
  17. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
    1999 891 citations Yi Zhang, Paul Tempst et al. Genes & Development profile →
  18. Caspase Cleaved BID Targets Mitochondria and Is Required for Cytochrome c Release, while BCL-XL Prevents This Release but Not Tumor Necrosis Factor-R1/Fas Death
    1999 876 citations Atan Gross, Xiao Ming Yin et al. Journal of Biological Chemistry profile →
  19. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform.
    1992 818 citations Paul Tempst et al. Proceedings of the National Academy of Sciences profile →
  20. Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
    2008 805 citations Paul Tempst et al. profile →
  21. Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal
    1990 785 citations Sankar Ghosh, Paul Tempst et al. Cell profile →
  22. GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR
    2003 772 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Molecular Cell profile →
  23. The Transcriptional Activity of NF-κB Is Regulated by the IκB-Associated PKAc Subunit through a Cyclic AMP–Independent Mechanism
    1997 732 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  24. Human SirT1 Interacts with Histone H1 and Promotes Formation of Facultative Heterochromatin
    2004 730 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Molecular Cell profile →
  25. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
    1999 718 citations Yi Zhang, Hediye Erdjument‐Bromage et al. profile →
  26. Immobilized Gallium(III) Affinity Chromatography of Phosphopeptides
    1999 708 citations Paul Tempst et al. profile →
  27. IκB-β regulates the persistent response in a biphasic activation of NF-κB
    1995 691 citations James E. Thompson, Hediye Erdjument‐Bromage et al. Cell profile →
  28. Regulation of p53 activity through lysine methylation
    2004 656 citations Paul Tempst, Danny Reinberg et al. profile →
  29. Methylation of H3-Lysine 79 Is Mediated by a New Family of HMTases without a SET Domain
    2002 650 citations Hengbin Wang, Hediye Erdjument‐Bromage et al. profile →
  30. JHDM2A, a JmjC-Containing H3K9 Demethylase, Facilitates Transcription Activation by Androgen Receptor
    2006 641 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  31. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FeγRIIB
    1996 632 citations Paul Tempst et al. profile →
  32. Histone Deimination Antagonizes Arginine Methylation
    2004 629 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  33. Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor
    2001 627 citations Hengbin Wang, Hediye Erdjument‐Bromage et al. Science profile →
  34. Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression
    2007 593 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  35. Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex
    1999 591 citations Matthew J. Gamble, Hediye Erdjument‐Bromage et al. profile →
  36. NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN
    2007 576 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →
  37. RSC, an Essential, Abundant Chromatin-Remodeling Complex
    1996 573 citations Lynne Lacomis, Hediye Erdjument‐Bromage et al. Cell profile →
  38. A Human Telomeric Protein
    1995 567 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Science profile →
  39. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic–leucine zipper protein
    1993 564 citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  40. DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide
    1991 547 citations Sankar Ghosh, Paul Tempst et al. Cell profile →
  41. An Iron Delivery Pathway Mediated by a Lipocalin
    2002 539 citations Jun Yang, David H. Goetz et al. Molecular Cell profile →
  42. Conversion of Proepithelin to Epithelins
    2002 527 citations Lynne Lacomis, Hediye Erdjument‐Bromage et al. Cell profile →
  43. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
    2006 505 citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  44. A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
    1994 452 citations Paul Tempst et al. Cell profile →
  45. The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
    2007 336 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Paul Tempst United States 143 62.1k 9.0k 8.7k 8.3k 7.7k 320 80.8k
Hediye Erdjument‐Bromage United States 125 53.4k 0.9× 6.9k 0.8× 7.7k 0.9× 7.4k 0.9× 6.7k 0.9× 285 68.1k
Nahum Sonenberg Canada 160 77.5k 1.2× 9.1k 1.0× 7.9k 0.9× 7.1k 0.9× 4.9k 0.6× 673 97.8k
Philip Cohen United Kingdom 143 67.4k 1.1× 8.8k 1.0× 13.5k 1.6× 9.8k 1.2× 7.9k 1.0× 489 89.2k
Stuart H. Orkin United States 157 51.2k 0.8× 12.1k 1.3× 7.8k 0.9× 5.8k 0.7× 8.2k 1.1× 539 76.4k
Harvey F. Lodish United States 150 49.1k 0.8× 8.7k 1.0× 12.2k 1.4× 9.4k 1.1× 15.7k 2.0× 646 82.0k
Dario R. Alessi United Kingdom 124 50.6k 0.8× 4.9k 0.5× 10.1k 1.2× 7.7k 0.9× 6.8k 0.9× 313 65.6k
Vamsi K. Mootha United States 87 51.6k 0.8× 7.3k 0.8× 6.1k 0.7× 7.0k 0.8× 10.7k 1.4× 199 72.9k
David M. Sabatini United States 129 71.6k 1.2× 10.4k 1.2× 13.4k 1.5× 9.5k 1.2× 11.4k 1.5× 257 101.0k
Guy S. Salvesen United States 110 37.2k 0.6× 9.6k 1.1× 5.5k 0.6× 9.0k 1.1× 5.7k 0.7× 295 54.7k
Stanley J. Korsmeyer United States 132 59.5k 1.0× 15.2k 1.7× 6.5k 0.7× 15.3k 1.8× 3.5k 0.5× 230 84.0k

Countries citing papers authored by Paul Tempst

Since Specialization
Citations

This map shows the geographic impact of Paul Tempst's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul Tempst with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul Tempst more than expected).

Fields of papers citing papers by Paul Tempst

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul Tempst. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul Tempst. The network helps show where Paul Tempst may publish in the future.

Co-authorship network of co-authors of Paul Tempst

This figure shows the co-authorship network connecting the top 25 collaborators of Paul Tempst. A scholar is included among the top collaborators of Paul Tempst based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul Tempst. Paul Tempst is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Vu, Ly, Fabiana Perna, Lan Wang, et al.. (2013). PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex. PMC. 1 indexed citations
2.
Cámara, Yolanda, Jorge Asin-Cayuela, Chan Bae Park, et al.. (2011). MTERF4 Regulates Translation by Targeting the Methyltransferase NSUN4 to the Mammalian Mitochondrial Ribosome. Cell Metabolism. 13(5). 527–539. 221 indexed citations
3.
Tae, Sookil, Vrajesh Karkhanis, Kevin Velasco, et al.. (2011). Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes. Nucleic Acids Research. 39(13). 5424–5438. 72 indexed citations
4.
Dale, Benjamin M., Daniel Traum, Hediye Erdjument‐Bromage, Paul Tempst, & Steven M. Greenberg. (2009). Phagocytosis in Macrophages Lacking Cbl Reveals an Unsuspected Role for Fcγ Receptor Signaling and Actin Assembly in Target Binding. The Journal of Immunology. 182(9). 5654–5662. 15 indexed citations
5.
Parmigiani, Raphael B., Weisheng Xu, Hediye Erdjument‐Bromage, et al.. (2008). HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation. Proceedings of the National Academy of Sciences. 105(28). 9633–9638. 12 indexed citations
6.
Zhai, Ling, et al.. (2007). Role of H2A deubiquitination in cell cycle progression and Hox gene expression. The FASEB Journal. 21(6). 2 indexed citations
7.
Yaneva, Mariana, Nan Wang, Qin Su, et al.. (2006). PU.1 and a TTTAAA Element in the Myeloid Defensin-1 Promoter Create an Operational TATA Box That Can Impose Cell Specificity onto TFIID Function. The Journal of Immunology. 176(11). 6906–6917. 11 indexed citations
8.
Villanueva, Josep, Kevin Lawlor, Ricardo Toledo‐Crow, & Paul Tempst. (2006). Automated serum peptide profiling. Nature Protocols. 1(2). 880–891. 62 indexed citations
9.
Chen, Ji‐Long, Raymond V. Fucini, Lynne Lacomis, et al.. (2005). Coatomer-bound Cdc42 regulates dynein recruitment to COPI vesicles. The Journal of Cell Biology. 169(3). 383–389. 80 indexed citations
10.
Gamble, Matthew J., Hediye Erdjument‐Bromage, Paul Tempst, Leonard P. Freedman, & Robert P. Fisher. (2005). The Histone Chaperone TAF-I/SET/INHAT Is Required for Transcription In Vitro of Chromatin Templates. Molecular and Cellular Biology. 25(2). 797–807. 59 indexed citations
11.
Fan, Melina, James A. Van Rhee, Julie St‐Pierre, et al.. (2004). Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: modulation by p38 MAPK. Genes & Development. 18(3). 278–289. 250 indexed citations
12.
Kuzmichev, Andrei, Thomas Jenuwein, Paul Tempst, & Danny Reinberg. (2004). Different Ezh2-Containing Complexes Target Methylation of Histone H1 or Nucleosomal Histone H3. Molecular Cell. 14(2). 183–193. 357 indexed citations
13.
Cao, Ru, Liangjun Wang, Hengbin Wang, et al.. (2002). Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing. Science. 298(5595). 1039–1043. 2927 indexed citations breakdown →
14.
Yang, Jun, David H. Goetz, Jau-Yi Li, et al.. (2002). An Iron Delivery Pathway Mediated by a Lipocalin. Molecular Cell. 10(5). 1045–1056. 539 indexed citations breakdown →
15.
Buckner, Frederick S., Kohei Yokoyama, Anita Grewal, et al.. (2000). Cloning, Heterologous Expression, and Distinct Substrate Specificity of Protein Farnesyltransferase from Trypanosoma brucei. Journal of Biological Chemistry. 275(29). 21870–21876. 43 indexed citations
16.
Haeseleer, Françoise, Izabela Sokal, Christophe L. M. J. Verlinde, et al.. (2000). Five Members of a Novel Ca2+-binding Protein (CABP) Subfamily with Similarity to Calmodulin. Journal of Biological Chemistry. 275(2). 1247–1260. 216 indexed citations
17.
Gross, Atan, Xiao Ming Yin, Michael C. Wei, et al.. (1999). Caspase Cleaved BID Targets Mitochondria and Is Required for Cytochrome c Release, while BCL-XL Prevents This Release but Not Tumor Necrosis Factor-R1/Fas Death. Journal of Biological Chemistry. 274(2). 1156–1163. 876 indexed citations breakdown →
18.
Thompson, James E., et al.. (1995). IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell. 80(4). 573–582. 691 indexed citations breakdown →
19.
Cortés, Patricia, et al.. (1994). The Recombination Signal Sequence-Binding Protein RBP-2N Functions as a Transcriptional Repressor. Molecular and Cellular Biology. 14(5). 3310–3319. 56 indexed citations
20.
Sasaki, Atsushi, Paul Tempst, Anthony S. Liotta, et al.. (1988). Isolation and Characterization of a Corticotropin-Releasing Hormone-Like Peptide From Human Placenta. The Journal of Clinical Endocrinology & Metabolism. 67(4). 768–773. 78 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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