Celeste M. Karch

16.5k total citations · 2 hit papers
75 papers, 5.0k citations indexed

About

Celeste M. Karch is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Celeste M. Karch has authored 75 papers receiving a total of 5.0k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Physiology, 36 papers in Molecular Biology and 20 papers in Neurology. Recurrent topics in Celeste M. Karch's work include Alzheimer's disease research and treatments (43 papers), Neuroinflammation and Neurodegeneration Mechanisms (17 papers) and Amyotrophic Lateral Sclerosis Research (13 papers). Celeste M. Karch is often cited by papers focused on Alzheimer's disease research and treatments (43 papers), Neuroinflammation and Neurodegeneration Mechanisms (17 papers) and Amyotrophic Lateral Sclerosis Research (13 papers). Celeste M. Karch collaborates with scholars based in United States, United Kingdom and Australia. Celeste M. Karch's co-authors include Alison Goate, Carlos Cruchaga, David Borchelt, Amanda T. Jeng, Sarah Bertelsen, Petra Nowotny, Janet Cady, P. John Hart, Mercedes Prudencio and Chihiro Sato and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Neuron.

In The Last Decade

Celeste M. Karch

70 papers receiving 4.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis

2014 953 citations Celeste M. Karch, Alison Goate Biological Psychiatry profile →
Tau Kinetics in Neurons and the Human Central Nervous System

2018 397 citations Chihiro Sato, Nicolas R. Barthélemy et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Celeste M. Karch United States	31	2.5k	2.0k	1.6k	846	767	75	5.0k
Rita Guerreiro United Kingdom	40	2.6k 1.0×	1.8k 0.9×	1.7k 1.1×	1.9k 2.2×	772 1.0×	130	5.6k
Yong Shen China	35	2.7k 1.1×	1.4k 0.7×	1.3k 0.8×	343 0.4×	774 1.0×	102	5.0k
Patrick M. Sullivan United States	51	3.5k 1.4×	3.3k 1.7×	1.5k 0.9×	654 0.8×	1.4k 1.9×	107	8.5k
Annakaisa Haapasalo Finland	36	2.0k 0.8×	2.1k 1.0×	862 0.5×	690 0.8×	1.4k 1.9×	109	5.3k
Diego Mastroeni United States	30	1.9k 0.8×	2.8k 1.4×	980 0.6×	381 0.5×	568 0.7×	60	4.6k
Luisa Benussi Italy	39	2.3k 0.9×	1.7k 0.9×	953 0.6×	1.3k 1.5×	504 0.7×	138	5.0k
Eloïse Hudry United States	28	1.8k 0.7×	1.8k 0.9×	1.1k 0.7×	321 0.4×	1.1k 1.4×	49	4.1k
Yuko Saito Japan	44	2.8k 1.1×	2.0k 1.0×	1.6k 1.0×	2.9k 3.4×	1.5k 2.0×	191	6.6k
Kristina Mullin United States	20	2.4k 1.0×	1.8k 0.9×	1.0k 0.7×	215 0.3×	642 0.8×	35	4.5k
Mary Beth Finn United States	19	2.9k 1.2×	1.2k 0.6×	1.5k 1.0×	405 0.5×	1.1k 1.5×	23	5.1k

Countries citing papers authored by Celeste M. Karch

Since Specialization

Citations

This map shows the geographic impact of Celeste M. Karch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Celeste M. Karch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Celeste M. Karch more than expected).

Fields of papers citing papers by Celeste M. Karch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Celeste M. Karch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Celeste M. Karch. The network helps show where Celeste M. Karch may publish in the future.

Co-authorship network of co-authors of Celeste M. Karch

This figure shows the co-authorship network connecting the top 25 collaborators of Celeste M. Karch. A scholar is included among the top collaborators of Celeste M. Karch based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Celeste M. Karch. Celeste M. Karch is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Theofilas, Panos, Chao Wang, David Butler, et al.. (2024). iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death. Molecular and Cellular Neuroscience. 130. 103954–103954.

Albanus, Ricardo D’Oliveira, Ekaterina Aladyeva, Taylor Bertucci, et al.. (2024). Uncovering the role of cerebrovascular phenotypes in AD through deep multi‐omic molecular profiling of human brains. Alzheimer s & Dementia. 20(S1). e089238–e089238.

Watanabe, Hirotaka, et al.. (2024). Inhibitory Roles ofApolipoprotein EChristchurch Astrocytes in Curbing Tau Propagation Using Human Pluripotent Stem Cell-Derived Models. Journal of Neuroscience. 44(24). e1709232024–e1709232024. 4 indexed citations

Schoch, Kathleen M., Hao Chen, Sarah E. Smith, et al.. (2023). Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice. PLoS ONE. 18(11). e0294731–e0294731. 3 indexed citations

Karch, Celeste M., et al.. (2023). Vascularized Brain Assembloids With Enhanced Cellular Complexity Provide Insights Into the Cellular Deficits of Tauopathy. Stem Cells. 42(2). 107–115. 11 indexed citations

Gabriel, Elke, Walid Albanna, Giovanni Pasquini, et al.. (2023). Generation of iPSC-derived human forebrain organoids assembling bilateral eye primordia. Nature Protocols. 18(6). 1893–1929. 10 indexed citations

Renganathan, Arun, Rita Martinez, Abdallah M. Eteleeb, et al.. (2023). Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. Molecular Psychiatry. 28(11). 4889–4901. 10 indexed citations

Li, Fuhai, Abdallah M. Eteleeb, William Buchser, et al.. (2022). Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer’s disease. Frontiers in Aging Neuroscience. 14. 935279–935279. 17 indexed citations

Sato, Chihiro, Elena Ficulle, Anan Yu, et al.. (2021). Recapitulation of Endogenous 4R Tau Expression and Formation of Insoluble Tau in Directly Reprogrammed Human Neurons. SSRN Electronic Journal. 5 indexed citations

10.

Gregory, James A., Catherine Braine, Miguel Cuevas, et al.. (2020). Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models. Cells. 9(6). 1406–1406. 4 indexed citations

11.

Nakamura, Mari, Seiji Shiozawa, Daisuke Tsuboi, et al.. (2019). Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs. Stem Cell Reports. 13(4). 684–699. 45 indexed citations

12.

Jensen, Nicholas O., et al.. (2018). RAB10: an Alzheimer’s disease resilience locus and potential drug target. Clinical Interventions in Aging. Volume 14. 73–79. 44 indexed citations

13.

Karch, Celeste M., Damián Hernández, Jen‐Chyong Wang, et al.. (2018). Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network. Alzheimer s Research & Therapy. 10(1). 69–69. 23 indexed citations

14.

Rodriguez‐Vieitez, Elena, Sigrid Botne Sando, Guro Berge, et al.. (2018). The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease. Acta Neuropathologica Communications. 6(1). 130–130. 56 indexed citations

15.

TCW, Julia, Minghui Wang, Anna A. Pimenova, et al.. (2017). An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 9(2). 600–614. 245 indexed citations

16.

Karch, Celeste M., Lubov Ezerskiy, Veronica Redaelli, et al.. (2015). Missense mutations in progranulin gene associated with frontotemporal lobar degeneration: study of pathogenetic features. Neurobiology of Aging. 38. 215.e1–215.e12. 17 indexed citations

17.

Karch, Celeste M. & Alison Goate. (2014). Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis. Biological Psychiatry. 77(1). 43–51. 953 indexed citations breakdown →

18.

Benítez, Bruno A., Celeste M. Karch, Yefei Cai, et al.. (2013). The PSEN1, p.E318G Variant Increases the Risk of Alzheimer's Disease in APOE-ε4 Carriers. PLoS Genetics. 9(8). e1003685–e1003685. 52 indexed citations

19.

Karch, Celeste M., Amanda T. Jeng, Petra Nowotny, et al.. (2012). Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains. PLoS ONE. 7(11). e50976–e50976. 262 indexed citations

20.

Kauwe, John, Carlos Cruchaga, Celeste M. Karch, et al.. (2011). Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease. PLoS ONE. 6(2). e15918–e15918. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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