Nikki J. Holbrook

34.3k total citations · 8 hit papers
154 papers, 29.2k citations indexed

About

Nikki J. Holbrook is a scholar working on Molecular Biology, Oncology and Physiology. According to data from OpenAlex, Nikki J. Holbrook has authored 154 papers receiving a total of 29.2k indexed citations (citations by other indexed papers that have themselves been cited), including 110 papers in Molecular Biology, 26 papers in Oncology and 24 papers in Physiology. Recurrent topics in Nikki J. Holbrook's work include Heat shock proteins research (21 papers), Cancer-related Molecular Pathways (19 papers) and Melanoma and MAPK Pathways (17 papers). Nikki J. Holbrook is often cited by papers focused on Heat shock proteins research (21 papers), Cancer-related Molecular Pathways (19 papers) and Melanoma and MAPK Pathways (17 papers). Nikki J. Holbrook collaborates with scholars based in United States, Germany and Poland. Nikki J. Holbrook's co-authors include Toren Finkel, Jennifer L. Martindale, Allan Munck, Myriam Gorospe, Paul M. Guyre, Xiantao Wang, Liu Y, Kathryn Z. Guyton, Karen D. McCullough and Lars‐Oliver Klotz and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Nikki J. Holbrook

154 papers receiving 28.3k citations

Hit Papers

Oxidants, oxidative stres... 1984 2026 1998 2012 2000 1984 2002 2001 1996 2.5k 5.0k 7.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Oxidants, oxidative stress and the biology of ageing
    2000 7.7k citations Nikki J. Holbrook et al. profile →
  2. Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*
    1984 2.5k citations Nikki J. Holbrook et al. profile →
  3. Cellular response to oxidative stress: Signaling for suicide and survival*
    2002 1.9k citations Jennifer L. Martindale, Nikki J. Holbrook profile →
  4. Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State
    2001 1.6k citations Jennifer L. Martindale, Nikki J. Holbrook et al. Molecular and Cellular Biology profile →
  5. Activation of Mitogen-activated Protein Kinase by H2O2
    1996 1.1k citations Kathryn Z. Guyton, Liu Y et al. Journal of Biological Chemistry profile →
  6. The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival
    1998 659 citations Xiantao Wang, Jennifer L. Martindale et al. profile →
  7. Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.
    1989 620 citations Albert J. Fornace, Daniel W. Nebert et al. Molecular and Cellular Biology profile →
  8. Requirement for ERK Activation in Cisplatin-induced Apoptosis
    2000 609 citations Xiantao Wang, Jennifer L. Martindale et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Nikki J. Holbrook United States 72 15.3k 4.0k 4.0k 3.7k 2.9k 154 29.2k
Peter Böhlen United States 85 15.8k 1.0× 2.8k 0.7× 1.6k 0.4× 1.9k 0.5× 4.6k 1.6× 223 27.7k
Jason D. Morrow United States 113 12.7k 0.8× 1.6k 0.4× 8.1k 2.0× 3.1k 0.8× 1.8k 0.6× 404 42.4k
Osamu Hayaishi Japan 98 13.6k 0.9× 1.8k 0.4× 3.5k 0.9× 2.9k 0.8× 4.0k 1.4× 531 30.5k
Edward J. Goetzl United States 94 13.6k 0.9× 2.1k 0.5× 6.2k 1.6× 5.8k 1.6× 1.9k 0.7× 380 26.6k
Masato Kasuga Japan 96 18.3k 1.2× 3.4k 0.8× 6.8k 1.7× 3.3k 0.9× 3.5k 1.2× 555 35.0k
Stuart A. Lipton United States 125 26.9k 1.8× 3.2k 0.8× 12.3k 3.1× 3.2k 0.9× 1.8k 0.6× 386 52.8k
Piotr Chomczyński United States 25 26.5k 1.7× 3.8k 0.9× 5.1k 1.3× 7.1k 1.9× 5.0k 1.7× 54 51.9k
Paul A. Insel United States 90 15.1k 1.0× 3.3k 0.8× 3.7k 0.9× 1.8k 0.5× 1.3k 0.5× 405 25.1k
Paolo Sassone‐Corsi France 118 23.4k 1.5× 2.5k 0.6× 9.7k 2.4× 3.2k 0.9× 3.3k 1.1× 433 48.2k
Pedro Cuatrecasas United States 104 23.0k 1.5× 3.9k 1.0× 4.8k 1.2× 3.4k 0.9× 2.4k 0.8× 362 35.6k

Countries citing papers authored by Nikki J. Holbrook

Since Specialization
Citations

This map shows the geographic impact of Nikki J. Holbrook's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nikki J. Holbrook with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nikki J. Holbrook more than expected).

Fields of papers citing papers by Nikki J. Holbrook

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nikki J. Holbrook. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nikki J. Holbrook. The network helps show where Nikki J. Holbrook may publish in the future.

Co-authorship network of co-authors of Nikki J. Holbrook

This figure shows the co-authorship network connecting the top 25 collaborators of Nikki J. Holbrook. A scholar is included among the top collaborators of Nikki J. Holbrook based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nikki J. Holbrook. Nikki J. Holbrook is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Buschmann, Thomas, Olga Potapova, Anat Bar‐Shira, et al.. (2001). Jun NH 2 -Terminal Kinase Phosphorylation of p53 on Thr-81 Is Important for p53 Stabilization and Transcriptional Activities in Response to Stress. Molecular and Cellular Biology. 21(8). 2743–2754. 240 indexed citations
2.
Kumaravel, T. S., Althaf Lohani, Amar Joshi, et al.. (2000). Enhanced sensitivity and long-term G2 arrest in hydrogen peroxide-treated Ku80-null cells are unrelated to DNA repair defects. Free Radical Biology and Medicine. 29(11). 1166–1176. 23 indexed citations
3.
Wang, Wengong, Henry Furneaux, Huiming Cheng, et al.. (2000). HuR Regulates p21 mRNA Stabilization by UV Light. Molecular and Cellular Biology. 20(3). 760–769. 472 indexed citations
4.
Wang, Xiantao, Jennifer L. Martindale, & Nikki J. Holbrook. (2000). Requirement for ERK Activation in Cisplatin-induced Apoptosis. Journal of Biological Chemistry. 275(50). 39435–39443. 609 indexed citations breakdown →
5.
Gorospe, Myriam, Josephine M. Egan, Berton Zbar, et al.. (1999). Protective Function of von Hippel-Lindau Protein against Impaired Protein Processing in Renal Carcinoma Cells. Molecular and Cellular Biology. 19(2). 1289–1300. 62 indexed citations
6.
Wang, Xian, et al.. (1999). Phorbol ester-induced mononuclear cell differentiation is blocked by the mitogen-activated protein kinase kinase (MEK) inhibitor PD98059.. PubMed. 10(5). 307–15. 38 indexed citations
7.
Chen, Wei, Jennifer L. Martindale, Nikki J. Holbrook, & Liu Y. (1998). Tumor Promoter Arsenite Activates Extracellular Signal-Regulated Kinase through a Signaling Pathway Mediated by Epidermal Growth Factor Receptor and Shc. Molecular and Cellular Biology. 18(9). 5178–5188. 136 indexed citations
8.
Gorospe, Myriam, Xiantao Wang, & Nikki J. Holbrook. (1998). p53-Dependent Elevation of p21 Waf1 Expression by UV Light Is Mediated through mRNA Stabilization and Involves a Vanadate-Sensitive Regulatory System. Molecular and Cellular Biology. 18(3). 1400–1407. 96 indexed citations
9.
Wolfgang, Curt D., Benjamin P.C. Chen, Jennifer L. Martindale, Nikki J. Holbrook, & Tsonwin Hai. (1997). gadd153/Chop10 , a Potential Target Gene of the Transcriptional Repressor ATF3. Molecular and Cellular Biology. 17(11). 6700–6707. 137 indexed citations
10.
Guyton, Kathryn Z., et al.. (1997). Oxidative Stress, Gene Expression, and the Aging Process. Cold Spring Harbor Monograph Archive. 34. 247–272. 9 indexed citations
11.
Choi, Augustine M.K., Steven R. Sylvester, Leo E. Otterbein, & Nikki J. Holbrook. (1995). Molecular Responses to Hyperoxia In Vivo: Relationship to Increased Tolerance in Aged Rats. American Journal of Respiratory Cell and Molecular Biology. 13(1). 74–82. 72 indexed citations
12.
Holbrook, Nikki J. & Robert Udelsman. (1994). 22 Heat Shock Protein Gene Expression in Response to Physiologic Stress and Aging. Cold Spring Harbor Monograph Archive. 26. 577–593. 25 indexed citations
13.
Park, Jong Sung, Jennifer D. Luethy, Joseph Fargnoli, et al.. (1992). Isolation, characterization and chromosomal localization of the human GADD153 gene. Gene. 116(2). 259–267. 119 indexed citations
14.
Garmyn, Maria, Mina Yaar, Nikki J. Holbrook, & Barbara A. Gilchrest. (1991). Immediate and delayed molecular response of human keratinocytes to solar-simulated irradiation.. PubMed. 65(4). 471–8. 58 indexed citations
15.
Fornace, Albert J., Daniel W. Nebert, M. Christine Hollander, et al.. (1989). Mammalian Genes Coordinately Regulated by Growth Arrest Signals and DNA-Damaging Agents. Molecular and Cellular Biology. 9(10). 4196–4203. 63 indexed citations
16.
Chopra, Rajesh, Nikki J. Holbrook, Douglas C. Powers, et al.. (1989). Interleukin 2, interleukin 2 receptor, and interferon-γ synthesis and mRNA expression in phorbol myristate acetate and calcium lonophore A23187-stimulated T cells from elderly humans. Clinical Immunology and Immunopathology. 53(2). 297–308. 67 indexed citations
17.
Nagel, Jürgen, Rajesh Chopra, Francis J. Chrest, et al.. (1988). Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors.. Journal of Clinical Investigation. 81(4). 1096–1102. 217 indexed citations
18.
Quinn, John P., Nikki J. Holbrook, & David Levens. (1987). Binding of a Cellular Protein to the Gibbon Ape Leukemia Virus Enhancer. Molecular and Cellular Biology. 7(8). 2735–2744. 35 indexed citations
19.
Holbrook, Nikki J., et al.. (1987). Transient Expression of Foreign Genes in Lymphoid Cells is Enhanced by Phorbol Ester. Molecular and Cellular Biology. 7(7). 2610–2613. 9 indexed citations
20.
Siekevitz, Miriam, Mark B. Feinberg, Nikki J. Holbrook, Flossie Wong‐Staal, & Warner C. Greene. (1987). Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.. Proceedings of the National Academy of Sciences. 84(15). 5389–5393. 377 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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