Alejandro Chavez

12.9k total citations · 4 hit papers
48 papers, 5.2k citations indexed

About

Alejandro Chavez is a scholar working on Molecular Biology, Infectious Diseases and Plant Science. According to data from OpenAlex, Alejandro Chavez has authored 48 papers receiving a total of 5.2k indexed citations (citations by other indexed papers that have themselves been cited), including 36 papers in Molecular Biology, 11 papers in Infectious Diseases and 7 papers in Plant Science. Recurrent topics in Alejandro Chavez's work include CRISPR and Genetic Engineering (27 papers), RNA and protein synthesis mechanisms (10 papers) and DNA Repair Mechanisms (8 papers). Alejandro Chavez is often cited by papers focused on CRISPR and Genetic Engineering (27 papers), RNA and protein synthesis mechanisms (10 papers) and DNA Repair Mechanisms (8 papers). Alejandro Chavez collaborates with scholars based in United States, Canada and Denmark. Alejandro Chavez's co-authors include George M. Church, James J. Collins, Marcelle Tuttle, Benjamin W. Pruitt, Dmitry Ter‐Ovanesyan, Samira Kiani, Suhani Vora, Benjamin E. Housden, Norbert Perrimon and Raj Chari and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Alejandro Chavez

45 papers receiving 5.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Highly efficient Cas9-mediated transcriptional programming

2015 1.2k citations Alejandro Chavez, Suhani Vora et al. profile →
Comparison of Cas9 activators in multiple species

2016 381 citations Alejandro Chavez, Marcelle Tuttle et al. profile →
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

2017 344 citations Alejandro Chavez, George M. Church et al. profile →
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir

2022 260 citations Sho Iketani, Hiroshi Mohri et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alejandro Chavez United States	27	4.3k	736	572	445	423	48	5.2k
Ella Hartenian United States	14	5.0k 1.2×	738 1.0×	446 0.8×	279 0.6×	389 0.9×	19	6.0k
Meagan E. Sullender United States	11	4.1k 1.0×	670 0.9×	249 0.4×	264 0.6×	450 1.1×	15	4.8k
Mudra Hegde United States	14	4.5k 1.0×	732 1.0×	135 0.2×	292 0.7×	462 1.1×	18	5.1k
Robert C. Orchard United States	22	2.7k 0.6×	703 1.0×	661 1.2×	135 0.3×	272 0.6×	45	4.1k
M. Inmaculada Barrasa United States	27	2.5k 0.6×	381 0.5×	411 0.7×	352 0.8×	204 0.5×	45	3.7k
Matthew H. Larson United States	14	8.2k 1.9×	2.0k 2.7×	182 0.3×	515 1.2×	658 1.6×	19	8.9k
Evan H. Whitehead United States	10	5.5k 1.3×	1.0k 1.4×	96 0.2×	405 0.9×	429 1.0×	20	6.2k
Gavin J. Knott United States	21	3.5k 0.8×	504 0.7×	140 0.2×	130 0.3×	385 0.9×	36	3.9k
Ann E. Sluder United States	28	1.4k 0.3×	389 0.5×	190 0.3×	708 1.6×	214 0.5×	53	3.3k

Countries citing papers authored by Alejandro Chavez

Since Specialization

Citations

This map shows the geographic impact of Alejandro Chavez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alejandro Chavez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alejandro Chavez more than expected).

Fields of papers citing papers by Alejandro Chavez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alejandro Chavez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alejandro Chavez. The network helps show where Alejandro Chavez may publish in the future.

Co-authorship network of co-authors of Alejandro Chavez

This figure shows the co-authorship network connecting the top 25 collaborators of Alejandro Chavez. A scholar is included among the top collaborators of Alejandro Chavez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alejandro Chavez. Alejandro Chavez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ausiello, Arturo, Marina López‐Olañeta, Juan Pablo Ochoa, et al.. (2025). CRISPR activation to repair electrocardiogram abnormalities caused by a FLNC truncating variant in mice. European Heart Journal. 46(43). 4610–4613.

Liu, Hengrui, Arie Zask, F. Forouhar, et al.. (2025). Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening. Nature Communications. 16(1). 152–152. 1 indexed citations

Kim, Joonwon, et al.. (2024). High-throughput tagging of endogenous loci for rapid characterization of protein function. Science Advances. 10(18). eadg8771–eadg8771. 2 indexed citations

Klompe, Sanne E., et al.. (2023). Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases. Nature Biotechnology. 42(1). 87–98. 80 indexed citations

Chavez, Alejandro, et al.. (2022). Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans. G3 Genes Genomes Genetics. 13(2). 13 indexed citations

Iketani, Sho, Hiroshi Mohri, Bruce Culbertson, et al.. (2022). Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir. Nature. 613(7944). 558–564. 260 indexed citations breakdown →

Iketani, Sho, F. Forouhar, Hengrui Liu, et al.. (2021). Author Correction: Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Communications. 12(1). 2708–2708. 8 indexed citations

Iketani, Sho, F. Forouhar, Hengrui Liu, et al.. (2021). Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Communications. 12(1). 2016–2016. 79 indexed citations

Moghadam, Farzaneh, Jeremy J. Velazquez, Nan Cher Yeo, et al.. (2020). Synthetic immunomodulation with a CRISPR super-repressor in vivo. Nature Cell Biology. 22(9). 1143–1154. 28 indexed citations

10.

Labun, Kornel, Xiaoge Guo, Alejandro Chavez, et al.. (2019). Accurate analysis of genuine CRISPR editing events with ampliCan. Genome Research. 29(5). 843–847. 46 indexed citations

11.

Chavez, Alejandro, Benjamin W. Pruitt, Marcelle Tuttle, et al.. (2018). Precise Cas9 targeting enables genomic mutation prevention. Proceedings of the National Academy of Sciences. 115(14). 3669–3673. 26 indexed citations

12.

Clarke, Ryan, Robert Heler, Nan Cher Yeo, et al.. (2018). Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks. Molecular Cell. 71(1). 42–55.e8. 102 indexed citations

13.

Chari, Raj, Nan Cher Yeo, Alejandro Chavez, & George M. Church. (2017). sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity. ACS Synthetic Biology. 6(5). 902–904. 174 indexed citations

14.

Chavez, Alejandro, Marcelle Tuttle, Raj Chari, et al.. (2015). Cas9 gRNA engineering for genome editing, activation and repression. DSpace@MIT (Massachusetts Institute of Technology). 1 indexed citations

15.

Glineburg, M. Rebecca, Alejandro Chavez, Vishesh Agrawal, Steven J. Brill, & F. Brad Johnson. (2013). Resolution by Unassisted Top3 Points to Template Switch Recombination Intermediates during DNA Replication. Journal of Biological Chemistry. 288(46). 33193–33204. 8 indexed citations

16.

Chavez, Alejandro, Vishesh Agrawal, & F. Brad Johnson. (2010). Homologous Recombination-dependent Rescue of Deficiency in the Structural Maintenance of Chromosomes (Smc) 5/6 Complex. Journal of Biological Chemistry. 286(7). 5119–5125. 33 indexed citations

17.

Chavez, Alejandro, Vanessa George, Vishesh Agrawal, & F. Brad Johnson. (2010). Sumoylation and the Structural Maintenance of Chromosomes (Smc) 5/6 Complex Slow Senescence through Recombination Intermediate Resolution. Journal of Biological Chemistry. 285(16). 11922–11930. 47 indexed citations

18.

Chavez, Alejandro, Amy M. Tsou, & F. Brad Johnson. (2009). Telomeres do the (un)twist: Helicase actions at chromosome termini. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1792(4). 329–340. 20 indexed citations

19.

Massip, Laurent, et al.. (2007). Werner syndrome protein prevents DNA breaks upon chromatin structure alteration. Aging Cell. 6(4). 471–481. 17 indexed citations

20.

Nollen, Ellen A. A., Susana M. D. A. Garcia, Gijs van Haaften, et al.. (2004). Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Proceedings of the National Academy of Sciences. 101(17). 6403–6408. 315 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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