Tohru Natsume

23.1k total citations · 5 hit papers
198 papers, 16.3k citations indexed

About

Tohru Natsume is a scholar working on Molecular Biology, Cell Biology and Epidemiology. According to data from OpenAlex, Tohru Natsume has authored 198 papers receiving a total of 16.3k indexed citations (citations by other indexed papers that have themselves been cited), including 163 papers in Molecular Biology, 54 papers in Cell Biology and 25 papers in Epidemiology. Recurrent topics in Tohru Natsume's work include Ubiquitin and proteasome pathways (38 papers), RNA Research and Splicing (34 papers) and Endoplasmic Reticulum Stress and Disease (33 papers). Tohru Natsume is often cited by papers focused on Ubiquitin and proteasome pathways (38 papers), RNA Research and Splicing (34 papers) and Endoplasmic Reticulum Stress and Disease (33 papers). Tohru Natsume collaborates with scholars based in Japan, United States and United Kingdom. Tohru Natsume's co-authors include Shun-ichiro Iemura, Noboru Mizushima, Shun‐ichiro Iemura, Taichi Hara, Keiji Tanaka, Jun‐Lin Guan, Chieko Kishi, Akito Takamura, Tomohisa Hatta and Shun-ichiro Iemura and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Tohru Natsume

195 papers receiving 16.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

2010 2.0k citations Masaaki Komatsu, Satoshi Waguri et al. profile →
Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

2009 1.6k citations Taichi Hara, Takeshi Kaizuka et al. Molecular Biology of the Cell profile →
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

2008 783 citations Taichi Hara, Akito Takamura et al. The Journal of Cell Biology profile →
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

2003 605 citations Noboru Mizushima, Tohru Natsume et al. profile →
The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

2014 379 citations Tomohisa Hatta, Tohru Natsume et al. Molecular Biology of the Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Tohru Natsume Japan	58	11.3k	5.1k	3.9k	1.5k	1.2k	198	16.3k
Gian María Fimia Italy	55	6.5k 0.6×	5.6k 1.1×	2.7k 0.7×	1.9k 1.3×	963 0.8×	156	14.7k
Éric Chevet France	56	6.8k 0.6×	4.0k 0.8×	6.6k 1.7×	1.1k 0.7×	1.4k 1.2×	189	13.1k
Jayanta Debnath United States	58	9.3k 0.8×	7.5k 1.5×	3.1k 0.8×	3.1k 2.1×	2.7k 2.3×	106	17.1k
Heidi M. McBride Canada	55	13.6k 1.2×	3.9k 0.8×	4.8k 1.2×	502 0.3×	888 0.8×	95	18.0k
Roberto Zoncu United States	45	12.6k 1.1×	4.8k 0.9×	4.8k 1.3×	1.3k 0.8×	2.9k 2.5×	71	20.2k
João A. Paulo United States	59	8.4k 0.7×	2.7k 0.5×	1.9k 0.5×	1.7k 1.1×	1.1k 0.9×	317	13.2k
Adi Kimchi Israel	67	13.0k 1.1×	6.9k 1.4×	2.8k 0.7×	3.9k 2.6×	2.1k 1.7×	156	20.0k
Suresh Subramani United States	76	15.7k 1.4×	3.2k 0.6×	2.2k 0.6×	1.2k 0.8×	1.1k 1.0×	209	19.4k
Andrew Thorburn United States	62	8.9k 0.8×	6.2k 1.2×	1.5k 0.4×	1.8k 1.2×	2.4k 2.0×	140	14.0k
Jonathan Backer United States	71	12.6k 1.1×	2.1k 0.4×	4.8k 1.2×	1.7k 1.1×	804 0.7×	147	17.4k

Countries citing papers authored by Tohru Natsume

Since Specialization

Citations

This map shows the geographic impact of Tohru Natsume's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tohru Natsume with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tohru Natsume more than expected).

Fields of papers citing papers by Tohru Natsume

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tohru Natsume. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tohru Natsume. The network helps show where Tohru Natsume may publish in the future.

Co-authorship network of co-authors of Tohru Natsume

This figure shows the co-authorship network connecting the top 25 collaborators of Tohru Natsume. A scholar is included among the top collaborators of Tohru Natsume based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tohru Natsume. Tohru Natsume is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Nozaki, Kyoko, Reiko Saito, Shuntaro Abe, et al.. (2025). Membrane topology inversion of GGCX mediates cytoplasmic carboxylation for antiviral defense. Science. 389(6755). 84–91.

Tajima, Kazuki, Hiroshi Yagi, Hisanobu Higashi, et al.. (2022). An organ-derived extracellular matrix triggers in situ kidney regeneration in a preclinical model. npj Regenerative Medicine. 7(1). 18–18. 13 indexed citations

Kanda, Genki N., Motoki Terada, Noriko Sakai, et al.. (2022). Robotic search for optimal cell culture in regenerative medicine. eLife. 11. 51 indexed citations

Ishimura, Ryosuke, Daisuke Noshiro, Yasuko Ono, et al.. (2022). The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3. Nature Communications. 13(1). 7857–7857. 50 indexed citations

Ninomiya, Kensuke, Junichi Iwakiri, Yuriko Sakaguchi, et al.. (2021). m ⁶ A modification of HSATIII lncRNAs regulates temperature‐dependent splicing. The EMBO Journal. 40(15). e107976–e107976. 49 indexed citations

Higashi, Hisanobu, Hiroshi Yagi, Kohei Kuroda, et al.. (2021). Transplantation of bioengineered liver capable of extended function in a preclinical liver failure model. American Journal of Transplantation. 22(3). 731–744. 13 indexed citations

Omori, Hiroko, Maho Hamasaki, Tomohisa Hatta, et al.. (2020). ERdj8 governs the size of autophagosomes during the formation process. The Journal of Cell Biology. 219(8). 21 indexed citations

Suzuki, Toru, Shungo Adachi, Shinsuke Shibata, et al.. (2020). Regulation of Fetal Genes by Transitions among RNA-Binding Proteins during Liver Development. International Journal of Molecular Sciences. 21(23). 9319–9319. 4 indexed citations

Aoyama-Ishiwatari, Saeko, et al.. (2020). NUDT21 Links Mitochondrial IPS-1 to RLR-Containing Stress Granules and Activates Host Antiviral Defense. The Journal of Immunology. 206(1). 154–163. 5 indexed citations

10.

Adachi, Shungo, et al.. (2019). Cell Stress Reduction by a Novel Perfusion-Culture System Using Commercial Culture Dish. Applied Sciences. 10(1). 95–95. 4 indexed citations

11.

Ohishi, Tomokazu, Haruka Yoshida, Masamichi Katori, et al.. (2017). Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion. Cancer Research. 77(9). 2328–2338. 32 indexed citations

12.

Morito, Daisuke, Tomohisa Hatta, Shun‐ichiro Iemura, et al.. (2017). Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor. Scientific Reports. 7(1). 44293–44293. 14 indexed citations

13.

Inoue, Takeshi, Masahiro Morita, Atsushi Hijikata, et al.. (2015). CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability. The Journal of Experimental Medicine. 212(9). 1465–1479. 43 indexed citations

14.

Kunoh, Tatsuki, Koichi Koseki, Motoki Takagi, et al.. (2010). A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer Cells. Molecular Cancer Therapeutics. 9(11). 2934–2942. 10 indexed citations

15.

Takeda, Kohsuke, Yosuke Ishida, Takuya Noguchi, et al.. (2009). Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1. Proceedings of the National Academy of Sciences. 106(30). 12301–12305. 118 indexed citations

16.

Hara, Taichi, Takeshi Kaizuka, Chieko Kishi, et al.. (2009). Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy. Molecular Biology of the Cell. 20(7). 1981–1991. 1642 indexed citations breakdown →

17.

Tatsumi, K., Yu‐shin Sou, Norihiro Tada, et al.. (2009). A Novel Type of E3 Ligase for the Ufm1 Conjugation System. Journal of Biological Chemistry. 285(8). 5417–5427. 191 indexed citations

18.

Yamada, Misato, Junji Ohnishi, Bisei Ohkawara, et al.. (2006). NARF, an Nemo-like Kinase (NLK)-associated Ring Finger Protein Regulates the Ubiquitylation and Degradation of T Cell Factor/Lymphoid Enhancer Factor (TCF/LEF). Journal of Biological Chemistry. 281(30). 20749–20760. 116 indexed citations

19.

Matsuda, Noriyuki, Masafumi Saijo, Shun‐ichiro Iemura, et al.. (2005). DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex. DNA repair. 4(5). 537–545. 61 indexed citations

20.

Hirota, Junji, Takayuki Michikawa, Tohru Natsume, Teiichi Furuichi, & Katsuhiko Mikoshiba. (1999). Calmodulin inhibits inositol 1,4,5‐trisphosphate‐induced calcium release through the purified and reconstituted inositol 1,4,5‐trisphosphate receptor type 1. FEBS Letters. 456(2). 322–326. 40 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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