Karen Hsiao

14.7k citations

37 papers · 11.6k indexed · 8 hit papers · h-index 26

Neurology top 0.05%
- Neurological diseases and metabolism 11
Physiology top 0.1%
- Alzheimer's disease research and treatments 17
Biological Psychiatry top 0.5%
- Tryptophan and brain disorders 2
Cellular and Molecular Neuroscience top 0.5%
- Nuclear Receptors and Signaling 5
Pharmacology top 0.2%
- Cholinesterase and Neurodegenerative Diseases 5
Molecular Biology
- Prion Diseases and Protein Misfolding 22
Nutrition and Dietetics
- Trace Elements in Health 10
Computational Theory and Mathematics
- Computational Drug Discovery Methods 4

Co-authors: Chris Eckman Steven G. Younkin Fusheng Yang Greg M. Cole Paul F. Chapman Steven P. Nilsen Yasuo Harigaya Stanley B. Prusiner
Cited by: Neurology Physiology Biological Psychiatry
Journals: Nature (1 paper)Science (2 papers)New England Journal of Medicine (1 paper)
Partner nations: United States United Kingdom Italy

In The Last Decade

Karen Hsiao

36 papers receiving 11.3k citations

Hit Papers

8 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

1999 Nature Neuroscience
1998 Nature Medicine
1998 PubMed
1997 Journal of Neuropathology & Experimental Neurology
1996 Science
1990 Science
1989 Nature
1988 Journal of Virology

Peers

Countries citing papers authored by Karen Hsiao

Since Specialization

Citations

This map shows the geographic impact of Karen Hsiao's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karen Hsiao with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karen Hsiao more than expected).

Fields of papers citing papers by Karen Hsiao

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karen Hsiao. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karen Hsiao. The network helps show where Karen Hsiao may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Karen Hsiao, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Karen Hsiao Line = papers co-authored together Karen Hsiao links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Induction of NADPH cytochrome P450 reductase by the Alzheimer β‐protein. Amyloid as a ‘foreign body’ Journal of Neurochemistry ·Miguel A. Pappolla,Rawhi Omar,Yau‐Jan Chyan,Jorge Ghiso,Karen Hsiao,Peter Bozner,George Perry,Mark A. Smith,Felix Cruz-Sánchez	2001	11
2	Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic micebreakdown → Nature Neuroscience ·Paul F. Chapman,Grace K. White,Matthew W. Jones,Deirdre Cooper-Blacketer,Vanessa Marshall,Michael C. Irizarry,Linda H. Younkin,Mark Good,T.V.P. Bliss,Bradley T. Hyman,Steven G. Younkin,Karen Hsiao	1999	773
3	SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein Nature Neuroscience ·Costantino Iadecola,Fangyi Zhang,Kiyoshi Niwa,Chris Eckman,Sherry Turner,Elizabeth R. Fischer,Steven G. Younkin,David Borchelt,Karen Hsiao,George A. Carlson	1999	334
4	Behavioral Changes in Transgenic Mice Expressing Both Amyloid Precursor Protein and Presenilin-1 Mutations: Lack of Association with Amyloid Deposits Behavior Genetics ·Leigh A. Holcomb,Marcia N. Gordon,Paul Jantzen,Karen Hsiao,Karen Duff,Dave Morgan	1999	288
5	Amyloid‐β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress Journal of Neurochemistry ·Mark A. Smith,Keisuke Hirai,Karen Hsiao,Miguel A. Pappolla,Peggy L.R. Harris,Sandra L. Siedlak,Massimo Tabaton,George Perry	1998	469
6	Transgenic mice expressing Alzheimer amyloid precursor proteins Experimental Gerontology ·Karen Hsiao	1998	96
7	Chapter 25 Strain dependent and invariant features of transgenic mice expressing Alzheimer amyloid precursor proteins Progress in brain research ·Karen Hsiao	1998	10
8	From prion diseases to Alzheimer’s disease PubMed ·Karen Hsiao	1997	6
9	APPSW Transgenic Mice Develop Age-related Aβ Deposits and Neuropil Abnormalities, but no Neuronal Loss in CA1breakdown → Journal of Neuropathology & Experimental Neurology ·Michael C. Irizarry,M. McNamara,Kerri L. Fedorchak,Karen Hsiao,Bradley T. Hyman	1997	526
10	Increased Susceptibility to Ischemic Brain Damage in Transgenic Mice Overexpressing the Amyloid Precursor Protein Journal of Neuroscience ·Fangyi Zhang,Chris Eckman,Steven G. Younkin,Karen Hsiao,Costantino Iadecola	1997	169
11	Genetic Modification of the Phenotypes Produced by Amyloid Precursor Protein Overexpression in Transgenic Mice Human Molecular Genetics ·George A. Carlson,David Borchelt,A. Dake,Sherry Turner,V. Danielson,J. Douglas Coffin,Christopher B. Eckman,Julia Meiners,Steven P. Nilsen,Steven G. Younkin,Karen Hsiao	1997	131
12	Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Micebreakdown → Science ·Karen Hsiao,Paul F. Chapman,Steven P. Nilsen,Chris Eckman,Yasuo Harigaya,Steven G. Younkin,Fusheng Yang,Greg M. Cole	1996	3504
13	Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins Neuron ·Karen Hsiao,David Borchelt,Kristine Olson,Rosa Johannsdottir,Cheryl A. Kitt,Wael S. Yunis,Sherry L. Xu,Chris Eckman,Steven G. Younkin,Donald A. Price,Costantino Iadecola,H. Brent Clark,George A. Carlson	1995	442
14	The Genetics and Transgenetics of Human Prion Disease Annals of the New York Academy of Sciences ·Karen Hsiao	1994	7
15	Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles Nature Genetics ·Karen Hsiao,Stephen R. Dlouhy,Martin R. Farlow,Carin Cass,Maria Da Costa,P. Michael Conneally,M. E. Hodes,Bernardino Ghetti,Stanley B. Prusiner	1992	174
16	A prion protein variant in a family with the telencephalic form of Gerstmann‐Straussler‐Scheinker syndrome Neurology ·Karen Hsiao,Carin Cass,Gerald D. Schellenberg,Thomas D. Bird,Evelyn A. Devine-Gage,H Wiśniewski,S. B. Prusiner	1991	120
17	Mutation of the Prion Protein in Libyan Jews with Creutzfeldt–Jakob Disease New England Journal of Medicine ·Karen Hsiao,Zeev Meiner,Esther Kahana,Carin Cass,Irit Kahana,Dana Avrahami,G. Scarlato,Oded Abramsky,Stanley B. Prusiner,Ruth Gabizon	1991	207
18	Molecular Genetics and Transgenic Model of Gertsmann???Str??ussler???Scheinker Disease Alzheimer Disease & Associated Disorders ·Karen Hsiao,Stanley B. Prusiner	1991	8
19	Spontaneous Neurodegeneration in Transgenic Mice with Prion Protein Codon 101 Proline → Leucine Substitutiona Annals of the New York Academy of Sciences ·Karen Hsiao,Michael Scott,Dallas Foster,Stephen J. DeArmond,Darlene Groth,Hana Serban,Stanley B. Prusiner	1991	12
20	Prion protein gene expression in cultured cells Protein Engineering Design and Selection ·Michael R. Scott,Darel A. Butler,Dale E. Bredesen,Monika Wälchli,Karen Hsiao,Stanley B. Prusiner	1988	42

About Karen Hsiao

Karen Hsiao is a scholar working on Neurology, Biological Psychiatry and Physiology, having authored 37 papers that have together received 11.6k indexed citations. Recurring topics across this work include Prion Diseases and Protein Misfolding (22 papers), Alzheimer's disease research and treatments (17 papers), Neurological diseases and metabolism (11 papers), Trace Elements in Health (10 papers), Nuclear Receptors and Signaling (5 papers), Cholinesterase and Neurodegenerative Diseases (5 papers), Computational Drug Discovery Methods (4 papers) and Tryptophan and brain disorders (2 papers). The work is most often cited by research in Neurology (3.9k citations), Physiology (7.3k citations) and Biological Psychiatry (578 citations). Karen Hsiao has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include Chris Eckman, Steven G. Younkin, Fusheng Yang, Greg M. Cole, Paul F. Chapman, Steven P. Nilsen, Yasuo Harigaya, Stanley B. Prusiner, Michael C. Irizarry and David Borchelt. Their work appears in journals such as Nature, Science and New England Journal of Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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