Ilse Dewachter

13.4k total citations · 3 hit papers
94 papers, 9.3k citations indexed

About

Ilse Dewachter is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Ilse Dewachter has authored 94 papers receiving a total of 9.3k indexed citations (citations by other indexed papers that have themselves been cited), including 76 papers in Physiology, 46 papers in Molecular Biology and 35 papers in Cellular and Molecular Neuroscience. Recurrent topics in Ilse Dewachter's work include Alzheimer's disease research and treatments (72 papers), Neuroinflammation and Neurodegeneration Mechanisms (18 papers) and Neuroscience and Neuropharmacology Research (18 papers). Ilse Dewachter is often cited by papers focused on Alzheimer's disease research and treatments (72 papers), Neuroinflammation and Neurodegeneration Mechanisms (18 papers) and Neuroscience and Neuropharmacology Research (18 papers). Ilse Dewachter collaborates with scholars based in Belgium, United States and Germany. Ilse Dewachter's co-authors include Fred Van Leuven, Dick Terwel, Peter Borghgraef, Michael T. Heneka, Magdalena Sastre, Thomas Klockgether, Ilie‐Cosmin Stancu, David M. Wilson, Mark Cookson and David M. Holtzman and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Ilse Dewachter

93 papers receiving 9.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hallmarks of neurodegenerative diseases

2023 875 citations David M. Wilson, Mark Cookson et al. Cell profile →
Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain

1999 553 citations Dieder Moechars, Ilse Dewachter et al. Journal of Biological Chemistry profile →
Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

2019 336 citations Ilie‐Cosmin Stancu, Niels Cremers et al. Acta Neuropathologica profile →

Peers

Countries citing papers authored by Ilse Dewachter

Since Specialization

Citations

This map shows the geographic impact of Ilse Dewachter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ilse Dewachter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ilse Dewachter more than expected).

Fields of papers citing papers by Ilse Dewachter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ilse Dewachter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ilse Dewachter. The network helps show where Ilse Dewachter may publish in the future.

Co-authorship network of co-authors of Ilse Dewachter

This figure shows the co-authorship network connecting the top 25 collaborators of Ilse Dewachter. A scholar is included among the top collaborators of Ilse Dewachter based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ilse Dewachter. Ilse Dewachter is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Gastrointestinal Dysfunction and Low‐Grade Inflammation Associate With Enteric Neuronal Amyloid‐β in a Model for Amyloid Pathology 2025 ·Neurogastroenterology & Motility ·(unknown), (unknown), (unknown), Marion J. Gijbels, Bert Brône, Ilse Dewachter, Veerle Melotte, Werend Boesmans	1
2	The Impact of Exercise Training on the Brain and Cognition in Type 2 Diabetes, and its Physiological Mediators: A Systematic Review 2025 ·Sports Medicine - Open ·(unknown), Ilse Dewachter, Koen Cuypers, Dominique Hansen	4
3	APOE deficiency inhibits amyloid-facilitated (A) tau pathology (T) and neurodegeneration (N), halting progressive ATN pathology in a preclinical model 2025 ·Molecular Psychiatry ·(unknown), A.J.M. Janssen, (unknown), (unknown), (unknown), (unknown), Sofie Kessels, (unknown), (unknown), Yanyan Wang, Ilie‐Cosmin Stancu, Andrei Segal, Markus Kleinewietfeld, Thomas Voets, Bert Brône, Suresh Poovathingal, Yeranddy A. Alpízar, Ilse Dewachter	1
4	The impact of exercise training on the brain and cognition in T2DM, and its physiological mediators: a systematic review 2024 ·medRxiv ·(unknown), Ilse Dewachter, Koen Cuypers, Dominique Hansen	2
5	Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models 2024 ·Acta Neuropathologica Communications ·(unknown), Luc Buée, Jean‐Pierre Brion, Tomáš Smolek, (unknown), Jozef Hritz, Tomáš Hromádka, Ilse Dewachter, Susanne Wegmann, Isabelle Landrieu, Petr Novák, Amritpal Mudher, Norbert Žilka	3
6	Dopamine-mediated striatal activity and function is enhanced in GlyRα2 knockout animals 2023 ·iScience ·(unknown), (unknown), Giovanni Morelli, Jean‐Michel Rigo, Rudi D’Hooge, Chadi Touma, Rupert Palme, Ilse Dewachter, Martin vandeVen, Victoria L. Harvey, Serge N. Schiffmann, Elisabeth Piccart, Bert Brône	2
7	Hallmarks of neurodegenerative diseases breakdown → 2023 ·Cell ·David M. Wilson, Mark Cookson, Ludo Van Den Bosch, Henrik Zetterberg, David M. Holtzman, Ilse Dewachter	875
8	The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model 2022 ·Glia ·Ilie‐Cosmin Stancu, (unknown), (unknown), (unknown), (unknown), Dick Terwel, Astrid Bottelbergs, Ilse Dewachter	42
9	Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention 2022 ·Acta Neuropathologica ·(unknown), (unknown), (unknown), (unknown), Ilie‐Cosmin Stancu, Ivo Lambrichts, (unknown), Rose Bruffaerts, Ilse Dewachter	13
10	CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia 2021 ·Acta Neuropathologica Communications ·(unknown), Isabelle Scheyltjens, Ilie‐Cosmin Stancu, (unknown), (unknown), (unknown), Tim Vanmierlo, Niels Cremers, Hannah Vanrusselt, Bert Brône, Bernard Hanseeuw, Jean‐Noël Octave, Astrid Bottelbergs, Kiavash Movahedi, Ilse Dewachter	31
11	Sex-regulated gene dosage effect of PPARα on synaptic plasticity 2019 ·Life Science Alliance ·Nathalie Pierrot, Laurence Ris, Ilie‐Cosmin Stancu, (unknown), (unknown), Donatienne Tyteca, Eric Baugé, Fanny Lalloyer, (unknown), Olivier Schakman, Karelle Leroy, Pascal Kienlen‐Campard, Philippe Gailly, Jean‐Pierre Brion, Ilse Dewachter, Bart Staels, Jean-Noël Octave	19
12	Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission 2017 ·Scientific Reports ·(unknown), (unknown), (unknown), (unknown), Peng Wang, Kunié Ando, Bernadette Tasiaux, Ilse Dewachter, Pascal Kienlen‐Campard, Jean‐Pierre Brion, Philippe Gailly, Jean‐Noël Octave, Nathalie Pierrot	26
13	Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo 2017 ·Acta Neuropathologica ·Peng Wang, Gérard Joberty, Arjan Buist, (unknown), Ilie‐Cosmin Stancu, Bruno Vasconcelos, Nathalie Pierrot, Maria Faelth-Savitski, Pascal Kienlen‐Campard, Jean‐Noël Octave, Marcus Bantscheff, Gerard Drewes, Diederik Moechars, Ilse Dewachter	91
14	Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells 2016 ·Frontiers in Aging Neuroscience ·(unknown), Serena Stanga, Jean‐Noël Octave, Ilse Dewachter, Steven O. Smith, Stefan N. Constantinescu, Pascal Kienlen‐Campard	24
15	Presenilin Transmembrane Domain 8 Conserved AXXXAXXXG Motifs Are Required for the Activity of the γ-Secretase Complex 2015 ·Journal of Biological Chemistry ·Claudia Marinangeli, Bernadette Tasiaux, (unknown), (unknown), Alejandro O. Sodero, Ilse Dewachter, J.N. Octave, Steven O. Smith, Stefan N. Constantinescu, Pascal Kienlen‐Campard	11
16	GSK-3 alpha/beta kinases and amyloid production in vivo 2011 ·Nature ·Tomasz Jaworski, Ilse Dewachter, Benoit Lechat, Maarten Gees, (unknown), David Demedts, Peter Borghgraef, Herman Devijver, (unknown), Satish Patel, James R. Woodgett, (unknown)	4
17	Neurodegeneration and Neuroinflammation in cdk5/p25-Inducible Mice 2008 ·American Journal Of Pathology ·David Muyllaert, Dick Terwel, (unknown), Kristina Sennvik, Peter Borghgraef, Herman Devijver, Ilse Dewachter, Fred Van Leuven	46
18	Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1 2007 ·Neurobiology of Aging ·Ilse Dewachter, (unknown), S. Croes, Peter Borghgraef, Herman Devijver, Thomas Voets, Bernd Nilius, Emile Godaux, F. Van Leuven	41
19	Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ 2006 ·Proceedings of the National Academy of Sciences ·Magdalena Sastre, Ilse Dewachter, Steffen Roßner, Nenad Bogdanović, Evan D. Rosen, Peter Borghgraef, Bernd O. Evert, Lucia Dumitrescu‐Ozimek, Dietmar Rudolf Thal, Gary E. Landreth, Jochen Walter, Thomas Klockgether, Fred Van Leuven, Michael T. Heneka	321
20	Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons 2000 ·American Journal Of Pathology ·Jo Van Dorpe, (unknown), Ilse Dewachter, Dieter Nuyens, Kurt Spittaels, Chris Van den Haute, Marc Mercken, Dieder Moechars, (unknown), Cuno Kuipéri, Koen Bruynseels, Ina Tesseur, Ruth J. F. Loos, Hugo Vanderstichele, Frédéric Checler, Raf Sciot, F. Van Leuven	189

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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