Jorge Ghiso

23.2k citations

213 papers · 17.3k indexed · 4 hit papers · h-index 70

Impact in

Physiology top 0.05%
- Alzheimer's disease research and treatments
Neurology top 0.1%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in

Physiology 167
- Alzheimer's disease research and treatments 164
Neurology 18
- Cerebrovascular and genetic disorders 17

Co-authors: Blas Frangione Agueda Rostagno Berislav V. Zloković Miguel Calero Thomas Wısnıewskı Tamás Révész Gordon T. Plant Rubén Vidal
Journals: Journal of Biological Chemistry (15 papers)Biochemical Journal (12 papers)Neurobiology of Aging (12 papers)Biochemical and Biophysical Research Communications (12 papers)Proceedings of the National Academy of Sciences (7 papers)
Partner nations: United States United Kingdom Japan

In The Last Decade

Jorge Ghiso

209 papers receiving 17.0k citations

Hit Papers

align trajectories log scale

Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host 2006 · 744 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2006 Science
2005 Proceedings of the National Academy of Sciences
2000 Journal of Clinical Investigation
1992 Science

Peers

Countries citing papers authored by Jorge Ghiso

Since Specialization

Citations

This map shows the geographic impact of Jorge Ghiso's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jorge Ghiso with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jorge Ghiso more than expected).

Fields of papers citing papers by Jorge Ghiso

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jorge Ghiso. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jorge Ghiso. The network helps show where Jorge Ghiso may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jorge Ghiso, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jorge Ghiso Line = papers co-authored together Jorge Ghiso links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Protocol for culture, purification, and target validation of a hybridoma-generated monoclonal antibody targeting Aβ truncated species STAR Protocols ·Fiona I. J. Crawford, Nanette Clinch, Danzengdeqiong, Hediye Erdjument‐Bromage, Christopher William, Thomas A. Neubert, Agueda Rostagno, Jorge Ghiso	2025	0
2	Functionally distinct pericyte subsets differently regulate amyloid‐β deposition in patients with Alzheimer's disease Brain Pathology ·Nathan Kozlowski, 郭少雅, Hamid Okhravi, Sunhee C. Lee, モハマドマスッドコリム, Thomas A. Neubert, Agueda Rostagno, Jorge Ghiso, Woong‐Ki Kim	2024	2
3	Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis Aging Cell ·Rebecca Parodi‐Rullán, Jorge Ghiso, С Н Федорова, Agueda Rostagno, Silvia Fossati	2020	49
4	Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage Alzheimer s Research & Therapy ·J Daradoumis, Jorge Ghiso, Agueda Rostagno	2020	56
5	The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain Neurobiology of Disease ·Silvia Fossati, Patrizia Giannoni, María E. Solesio, Sarah L. Cocklin, С Н Федорова, Jorge Ghiso, Agueda Rostagno	2015	77
6	BRI2 Interacts with BACE1 and Reduces its Cellular Levels by Reducing the Levels of BACE1 mRNA and Inducing its Degradation Through the Lysosomal Pathway. Current Alzheimer Research ·Maria Tsachaki, TAM Tassin, Nefeli Slavi, 郭玉宁, Jorge Ghiso, Spiros Efthimiopoulos	2013	1
7	Biochemical analysis of myoglobinuria associated with rhabdomyolysis Acta bioquímica clínica latinoamericana ·Agueda Rostagno, Jorge Ghiso	2013	1
8	Major Carboxyl Terminal Fragments Generated by γ-Secretase Processing of the Alzheimer Amyloid Precursor Are 50 and 51 Amino Acids Long American Journal of Geriatric Psychiatry ·Inga Pinnix, Jorge Ghiso, Miguel A. Pappolla, Kumar Sambamurti	2013	11
9	MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells Molecular Biology of the Cell ·Ge Zhou, Feng‐Xia Liang, Rok Romih, Zefang Wang, Yi Liao, Jorge Ghiso, José L. Luque-García, Thomas A. Neubert, Gert Kreibich, Miguel A. Alonso, Nicole Schaeren‐Wiemers, Tung‐Tien Sun	2012	29
10	Insights into Caspase-Mediated Apoptotic Pathways Induced by Amyloid-β in Cerebral Microvascular Endothelial Cells Neurodegenerative Diseases ·Silvia Fossati, Jorge Ghiso, Agueda Rostagno	2011	38
11	Matrix Metalloproteinase 2 (MMP-2) Degrades Soluble Vasculotropic Amyloid-β E22Q and L34V Mutants, Delaying Their Toxicity for Human Brain Microvascular Endothelial Cells Journal of Biological Chemistry ·Mar Hernández‐Guillamón, Илья Дмитриевич Черкашин, Silvia Fossati, Steven P. Blais, Mireia Parés, Anna Peñalba, Merçé Boada, Pierre‐Olivier Couraud, Thomas A. Neubert, Joan Montaner, Jorge Ghiso, Agueda Rostagno	2010	42
12	Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies (vol 118, pg 115, 2009) UCL Discovery (University College London) ·Tamás Révész, (unknown), Tammaryn Lashley, (unknown), (unknown), Agueda Rostagno, Jorge Ghiso	2009	0
13	Familial cerebral amyloid angiopathy related to stroke and dementia. PubMed ·B Frangione, T Révész, Rubén Vidal, Janice L. Holton, Tammaryn Lashley, Henry Houlden, Nicholas Wood, Agueda Rostagno, Gordon T. Plant, Jorge Ghiso	2001	23
14	Induction of NADPH cytochrome P450 reductase by the Alzheimer β‐protein. Amyloid as a ‘foreign body’ Journal of Neurochemistry ·Miguel A. Pappolla, Rawhi Omar, Yau‐Jan Chyan, Jorge Ghiso, Karen Hsiao, Peter Bozner, George Perry, Mark A. Smith, Felix Cruz-Sánchez	2001	11
15	Amyloid and Nonfibrillar Deposits in Mice Transgenic for Wild-Type Human Transthyretin: A Possible Model for Senile Systemic Amyloidosis Laboratory Investigation ·Igor Lemos Duarte, Sai U. Abdulkhazhieva, Rubén Vidal, Jorge Ghiso, Asok Kumar, Rahmin A. Rabenou, 于春评, Daniel R. Jacobson, Clément E. Tagoe, Gloria Gallo, Joel N. Buxbaum	2001	79
16	An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease Journal of Neural Transmission ·Henry James, Yau‐Jan Chyan, Burkhard Pöeggeler, Blas Frangione, Pavel Všetička, Jorge Ghiso, Rüssel J. Reiter	2000	214
17	A Newly Formed Amyloidogenic Fragment due to a Stop Codon Mutation Causes Familial British Dementia Annals of the New York Academy of Sciences ·Jorge Ghiso, Rubén Vidal, Agueda Rostagno, Simon Mead, Tamás Révész, Gordon T. Plant, Blas Frangione	2000	34
18	Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer. Journal of Clinical Investigation ·Jasmina B. Mačkić, Monique F. Stins, J. Gordon McComb, Miguel Calero, Jorge Ghiso, Victoria Clark, S D Yan, D Stern, A M Schmidt, Blas Frangione, Berislav V. Zloković	1998	200
19	Mutation in gelsolin gene in Finnish hereditary amyloidosis. The Journal of Experimental Medicine ·Efrat Levy, Matti Haltia, Ivan Fernandez‐Madrid, E. Matzger, Jorge Ghiso, Frances Prelli, Blas Frangione	1990	120
20	The complete amino acid sequence of toxin TsTX-VI isolated from the venom of the scorpionTityus serrulatus Journal of Protein Chemistry ·Sérgio Marangoni, Jorge Ghiso, Suely Vilela Sampaio, Eliane Candiani Arantes, José R. Giglio, Benedito Oliveira, J Zhang	1990	35

About Jorge Ghiso

Jorge Ghiso is a scholar working on Physiology, Neurology, Biological Psychiatry, Molecular Biology and Neurology, having authored 213 papers that have together received 17.3k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (164 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (66 papers), Prion Diseases and Protein Misfolding (36 papers), S100 Proteins and Annexins (22 papers), Cerebrovascular and genetic disorders (17 papers), Clusterin in disease pathology (16 papers), Computational Drug Discovery Methods (14 papers) and Nuclear Receptors and Signaling (11 papers). The work is most often cited by research in Physiology (11.8k citations), Neurology (2.8k citations), Biological Psychiatry (582 citations), Neurology (2.1k citations) and Molecular Biology (8.5k citations). Jorge Ghiso has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Blas Frangione, Agueda Rostagno, Berislav V. Zloković, Miguel Calero, Thomas Wısnıewskı, Tamás Révész, Gordon T. Plant, Rubén Vidal, Etsuro Matsubara and E. Matsubara. Their work appears in journals such as Journal of Biological Chemistry, Biochemical Journal, Neurobiology of Aging, Biochemical and Biophysical Research Communications and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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