Dale E. Bredesen

37.4k citations

232 papers · 28.9k indexed · 16 hit papers · h-index 83

Impact in

Developmental Neuroscience top 0.1%
Cellular and Molecular Neuroscience top 0.1%
- Neuroscience and Neuropharmacology Research
- Nerve injury and regeneration

Papers in

Cellular and Molecular Neuroscience 63
- Neuroscience and Neuropharmacology Research 19
- Nuclear Receptors and Signaling 17
Aging 6

Co-authors: Rammohan V. Rao Lisa Ellerby H. Michael Ellerby Shahrooz Rabizadeh Patrick Mehlen Darci J. Kane Robert M. Levy John C. Reed
Journals: Journal of Biological Chemistry (16 papers)Proceedings of the National Academy of Sciences (14 papers)Journal of Neurochemistry (13 papers)Journal of Alzheimer s Disease (12 papers)Cell Death and Differentiation (11 papers)
Partner nations: United States France Canada

In The Last Decade

Dale E. Bredesen

231 papers receiving 28.2k citations

Hit Papers

15 papers align trajectories log scale

Neuroprotective Herbs for the Management of Alzheimer’s Disease 2021 · 146 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Biomolecules
2010 PLoS ONE
2004 Cell Death and Differentiation
2002 FEBS Letters
2001 Journal of Biological Chemistry
2001 Journal of Biological Chemistry
2000 Proceedings of the National Academy of Sciences
1999 Nature Medicine
1998 Journal of Biological Chemistry
1998 Proceedings of the National Academy of Sciences
1997 Journal of Neuroscience
1996 Science
1993 Science
1993 Science
1993 Proceedings of the National Academy of Sciences
1985 Journal of neurosurgery

Peers

Countries citing papers authored by Dale E. Bredesen

Since Specialization

Citations

This map shows the geographic impact of Dale E. Bredesen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dale E. Bredesen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dale E. Bredesen more than expected).

Fields of papers citing papers by Dale E. Bredesen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dale E. Bredesen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dale E. Bredesen. The network helps show where Dale E. Bredesen may publish in the future.

Co-authors

The 25 scholars most cited alongside Dale E. Bredesen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dale E. Bredesen Line = papers co-authored together Dale E. Bredesen links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Ayurvedic Profiling of Alzheimer's Disease. PubMed ·Dale E. Bredesen, Rammohan V. Rao	2017	9
2	Hot Topics in Research: Preventive Neuroradiology in Brain Aging and Cognitive Decline American Journal of Neuroradiology ·Cyrus A. Raji, Harris A. Eyre, Shaobin Wei, Dale E. Bredesen, Steven Moylan, Marcus Law, Gary W. Small, Paul M. Thompson, Robert M. Friedlander, Daniel Silverman, Bernhard T. Baune, T.A. Hoang, Noriko Salamon, Arthur W. Toga, Meike W. Vernooij	2015	10
3	Moonlighting Peptides with Emerging Function PLoS ONE ·Jonathan G. Rodríguez Plaza, Amanda Villalón Rojas, Sur Herrera Paredes, Georgina Garza‐Ramos, Alfredo Torres‐Larios, Carlos Amero, Gabriela Zarraga Granados, Manuel Gutiérrez‐Aguilar, María Teresa Lara Ortiz, Carlos Polanco, Salvador Uribe‐Carvajal, Roberto Coria, Antonio Peña Díaz, Dale E. Bredesen, Susana Castro‐Obregón, Gabriel del Rio	2012	16
4	Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease PLoS ONE ·Patricia Spilman, Natalia Podlutskaya, Matthew J. Hart, Jayanta Debnath, Olivia Gorostiza, Dale E. Bredesen, Arlan Richardson, Randy Strong, Verónica Galván	2011	2
5	In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid β-peptide of APP Free Radical Biology and Medicine ·D. Allan Butterfield, Verónica Galván, Miranda Bader Lange, Huidong Tang, Renã A. Sowell, Patricia Spilman, Joanna Fombonne, Olivia Gorostiza, Junli Zhang, Rukhsana Sultana, Dale E. Bredesen	2009	166
6	Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: A role for early experience Behavioural Brain Research ·Junli Zhang, Olivia Gorostiza, Huidong Tang, Dale E. Bredesen, Verónica Galván	2009	20
7	Netrin-1 interacts with amyloid precursor protein and regulates amyloid-β production Cell Death and Differentiation ·Filipe C. Lourenço, Verónica Galván, Joanna Fombonne, Véronique Corset, Fabien Llambi, Ulrike Müller, Dale E. Bredesen, Patrick Mehlen	2009	80
8	Coupling Endoplasmic Reticulum Stress to the Cell Death Program in Dopaminergic Cells: Effect of Paraquat NeuroMolecular Medicine ·Shankar J. Chinta, Anand Rane, Karen S. Poksay, Dale E. Bredesen, Julie K. Andersen, Rammohan V. Rao	2008	45
9	Endoplasmic reticulum stress-induced cell death mediated by the proteasome Cell Death and Differentiation ·Lotti Egger, David T. Madden, C Rhême, Rammohan V. Rao, Dale E. Bredesen	2007	52
10	A Calpain-Like Protease Inhibits Autophagic Cell Death Autophagy ·David T. Madden, Lotti Egger, Dale E. Bredesen	2007	40
11	Differential regulation of the intrinsic pathway of apoptosis in brain and liver during ageing FEBS Letters ·Veronika Stoka, Vito Türk, Dale E. Bredesen	2006	20
12	Developmental shift in the apostat: Comparison of neurones and astrocytes FEBS Letters ·Veronika Stoka, Sylvia F. Chen, Vito Türk, Dale E. Bredesen	2005	3
13	Alzheimer病トランスジェニック(PDGF‐APPSw,Ind)マウス Proc Natl Acad Sci USA ·Ketao Jin, Galvan, Xie Li, Mao X O, Olivia Gorostiza, Dale E. Bredesen, David A. Greenberg	2004	76
14	Rebuttal to Austad: ‘Is aging programmed? Aging Cell ·Dale E. Bredesen	2004	6
15	The dependence receptor hypothesis APOPTOSIS ·Patrick Mehlen, Dale E. Bredesen	2004	91
16	Target-Assisted Iterative Screening of Phage Surface Display cDNA Libraries Humana Press eBooks ·Alexei Kurakin, Susan C. Wu, Dale E. Bredesen	2004	9
17	Caspase cleavage of the amyloid precursor protein modulates amyloid β‐protein toxicity Journal of Neurochemistry ·Daniel C. Lu, Salvador Soriano, Dale E. Bredesen, Edward H. Koo	2003	87
18	Loss of Oxidation-Reduction Specificity in Amyotrophic Lateral Sclerosis-Associated CuZnSOD Mutants Journal of Molecular Neuroscience ·Carla Café, Maria Pia Testa, Patrick J. Sheldon, William P. French, Lisa Ellerby, Dale E. Bredesen	2000	4
19	Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species Science ·Darci J. Kane, Theodore A. Sarafian, Rein Anton, Hejin P. Hahn, E B Gralla, Joan Selverstone Valentine, T. Örd, Dale E. Bredesen Hit paper breakdown →	1993	1483
20	Increasing the proliferative capacity of muscular dystrophy myoblasts Muscle & Nerve ·Jie Yang, M Seelig, Sylvia A. Rayner, Dale E. Bredesen	1992	2

About Dale E. Bredesen

Dale E. Bredesen is a scholar working on Cellular and Molecular Neuroscience, Aging, Physiology, Developmental Neuroscience and Cell Biology, having authored 232 papers that have together received 28.9k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (65 papers), Cell death mechanisms and regulation (48 papers), Mitochondrial Function and Pathology (27 papers), Endoplasmic Reticulum Stress and Disease (23 papers), Autophagy in Disease and Therapy (22 papers), Cholinesterase and Neurodegenerative Diseases (20 papers), Neuroscience and Neuropharmacology Research (19 papers) and Nuclear Receptors and Signaling (17 papers). The work is most often cited by research in Developmental Neuroscience (1.6k citations), Cellular and Molecular Neuroscience (6.6k citations), Cell Biology (4.2k citations), Molecular Biology (16.6k citations) and Aging (412 citations). Dale E. Bredesen has collaborated with scholars based in United States, France and Canada. Frequent co-authors include Rammohan V. Rao, Lisa Ellerby, H. Michael Ellerby, Shahrooz Rabizadeh, Patrick Mehlen, Darci J. Kane, Robert M. Levy, John C. Reed, Mark L. Rosenblum and Sabina Sperandio. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Journal of Neurochemistry, Journal of Alzheimer s Disease and Cell Death and Differentiation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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