Darlene Groth

16.7k total citations · 12 hit papers
69 papers, 13.3k citations indexed

About

Darlene Groth is a scholar working on Molecular Biology, Nutrition and Dietetics and Neurology. According to data from OpenAlex, Darlene Groth has authored 69 papers receiving a total of 13.3k indexed citations (citations by other indexed papers that have themselves been cited), including 65 papers in Molecular Biology, 33 papers in Nutrition and Dietetics and 23 papers in Neurology. Recurrent topics in Darlene Groth's work include Prion Diseases and Protein Misfolding (63 papers), Trace Elements in Health (33 papers) and Neurological diseases and metabolism (23 papers). Darlene Groth is often cited by papers focused on Prion Diseases and Protein Misfolding (63 papers), Trace Elements in Health (33 papers) and Neurological diseases and metabolism (23 papers). Darlene Groth collaborates with scholars based in United States, Germany and Sweden. Darlene Groth's co-authors include Stanley B. Prusiner, Fred E. Cohen, Marilyn Torchia, Michael P. McKinley, Stephen J. DeArmond, Michael Scott, Ana Serban, David C. Bolton, Ingrid Mehlhorn and Dallas Foster and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Darlene Groth

69 papers receiving 12.9k citations

Hit Papers

Conversion of alpha-helices into beta-sheets features in ... 1982 2026 1996 2011 1993 1998 1983 1990 1986 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.
    1993 1.8k citations K M Pan, M. A. Baldwin et al. profile →
  2. Eight prion strains have PrPSc molecules with different conformations
    1998 1.0k citations Jiri Safar, Holger Wille et al. Nature Medicine profile →
  3. Scrapie prions aggregate to form amyloid-like birefringent rods
    1983 848 citations Stanley B. Prusiner, Michael P. McKinley et al. Cell profile →
  4. Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
    1990 700 citations Stanley B. Prusiner, Michael Scott et al. Cell profile →
  5. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
    1986 632 citations Michael Scott, David Westaway et al. Cell profile →
  6. Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
    1989 557 citations Michael Scott, Dallas Foster et al. Cell profile →
  7. Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
    1990 414 citations Karen Hsiao, Michael Scott et al. profile →
  8. Purification and structural studies of a major scrapie prion protein
    1984 387 citations Stanley B. Prusiner, Darlene Groth et al. Cell profile →
  9. Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform
    1997 382 citations Kiyotoshi Kaneko, Darlene Groth et al. profile →
  10. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
    1993 373 citations Stanley B. Prusiner, Darlene Groth et al. profile →
  11. Further purification and characterization of scrapie prions
    1982 368 citations Stanley B. Prusiner, Darlene Groth et al. profile →
  12. Measurement of the scrapie agent using an incubation time interval assay
    1982 292 citations Stanley B. Prusiner, Darlene Groth et al. Annals of Neurology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Darlene Groth United States 49 12.9k 7.0k 5.8k 1.3k 581 69 13.3k
Richard Race United States 46 6.9k 0.5× 3.5k 0.5× 2.8k 0.5× 954 0.7× 329 0.6× 95 7.7k
Holger Wille United States 42 6.4k 0.5× 2.7k 0.4× 2.3k 0.4× 1.9k 1.4× 453 0.8× 121 7.5k
Gregory J. Raymond United States 35 6.4k 0.5× 3.3k 0.5× 2.5k 0.4× 875 0.7× 340 0.6× 55 6.7k
Jean Manson United Kingdom 41 6.1k 0.5× 3.3k 0.5× 2.6k 0.4× 932 0.7× 310 0.5× 120 6.7k
Richard I. Carp United States 44 5.2k 0.4× 2.3k 0.3× 2.1k 0.4× 934 0.7× 355 0.6× 202 6.5k
Simone Hornemann Switzerland 34 5.3k 0.4× 2.7k 0.4× 2.3k 0.4× 855 0.7× 190 0.3× 70 6.0k
Joaquı́n Castilla Spain 41 5.1k 0.4× 2.3k 0.3× 1.7k 0.3× 840 0.6× 259 0.4× 112 5.9k
Suzette A. Priola United States 37 4.7k 0.4× 2.6k 0.4× 1.9k 0.3× 615 0.5× 256 0.4× 84 5.0k
Surachai Supattapone United States 39 6.3k 0.5× 1.8k 0.3× 1.7k 0.3× 848 0.6× 211 0.4× 91 7.2k
Christina J. Sigurdson United States 42 4.4k 0.3× 1.6k 0.2× 1.1k 0.2× 1.6k 1.2× 418 0.7× 84 5.8k

Countries citing papers authored by Darlene Groth

Since Specialization
Citations

This map shows the geographic impact of Darlene Groth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darlene Groth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darlene Groth more than expected).

Fields of papers citing papers by Darlene Groth

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darlene Groth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darlene Groth. The network helps show where Darlene Groth may publish in the future.

Co-authorship network of co-authors of Darlene Groth

This figure shows the co-authorship network connecting the top 25 collaborators of Darlene Groth. A scholar is included among the top collaborators of Darlene Groth based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Darlene Groth. Darlene Groth is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Giles, Kurt, David V. Glidden, Smita S. Patel, et al.. (2010). Human prion strain selection in transgenic mice. Annals of Neurology. 68(2). 151–161. 36 indexed citations
2.
Philipp, W., Darlene Groth, Kurt Giles, et al.. (2007). Transgenic mouse brains for the evaluation and quality control of BSE tests. Biological Chemistry. 388(3). 349–354. 3 indexed citations
3.
Diez, Margarita, Darlene Groth, Stephen J. DeArmond, Stanley B. Prusiner, & Tomas Hökfelt. (2006). Changes in neuropeptide expression in mice infected with prions. Neurobiology of Aging. 28(5). 748–765. 9 indexed citations
4.
Safar, Jiri, Ana Serban, Darlene Groth, et al.. (2005). Search for a Prion-Specific Nucleic Acid. Journal of Virology. 79(16). 10796–10806. 100 indexed citations
5.
Safar, Jiri, Michael Scott, Camille Deering, et al.. (2002). Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice. Nature Biotechnology. 20(11). 1147–1150. 195 indexed citations
6.
Diez, Margarita, S. J. DeArmond, Darlene Groth, Stanley B. Prusiner, & Tomas Hökfelt. (2001). Decreased MK-801 Binding in Discrete Hippocampal Regions of Prion-Infected Mice. Neurobiology of Disease. 8(4). 692–699. 10 indexed citations
7.
Peretz, David, Michael R. Scott, Darlene Groth, et al.. (2001). Strain‐specified relative conformational stability of the scrapie prion protein. Protein Science. 10(4). 854–863. 204 indexed citations
8.
Kaneko, Kiyotoshi, Haydn L. Ball, Holger Wille, et al.. (2000). A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice. Journal of Molecular Biology. 295(4). 997–1007. 114 indexed citations
9.
Tatzelt, Jörg, Darlene Groth, Marilyn Torchia, Stanley B. Prusiner, & Stephen J. DeArmond. (1999). Kinetics of Prion Protein Accumulation in the CNS of Mice with Experimental Scrapie. Journal of Neuropathology & Experimental Neurology. 58(12). 1244–1249. 30 indexed citations
10.
Safar, Jiri, Holger Wille, Vincenza Itri, et al.. (1998). Eight prion strains have PrPSc molecules with different conformations. Nature Medicine. 4(10). 1157–1165. 1010 indexed citations breakdown →
11.
Scott, Michael R., Darlene Groth, Jörg Tatzelt, et al.. (1997). Propagation of prion strains through specific conformers of the prion protein. Journal of Virology. 71(12). 9032–9044. 74 indexed citations
12.
Diez, Margarita, Jari Koıstınaho, Stephen J. DeArmond, et al.. (1996). Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice. Neuroreport. 7(12). 1887–1892. 7 indexed citations
13.
Baldwin, M. A., K M Pan, Jack Nguyen, et al.. (1994). Spectroscopic characterization of conformational differences between PrPC and PrPSc: an α-helix to β-sheet transition. Philosophical Transactions of the Royal Society B Biological Sciences. 343(1306). 435–441. 34 indexed citations
14.
Westaway, David, Stephen J. DeArmond, Darlene Groth, et al.. (1994). Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell. 76(1). 117–129. 276 indexed citations
15.
Hsiao, Karen, Michael Scott, Dallas Foster, et al.. (1991). Spontaneous Neurodegeneration in Transgenic Mice with Prion Protein Codon 101 Proline → Leucine Substitutiona. Annals of the New York Academy of Sciences. 640(1). 166–170. 12 indexed citations
16.
Prusiner, Stanley B., Michael Scott, Dallas Foster, et al.. (1990). Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell. 63(4). 673–686. 700 indexed citations breakdown →
17.
Scott, Michael, Dallas Foster, C. Mirenda, et al.. (1990). TRANSGENIC MICE EXPRESSING HAMSTER PRION PROTEIN PRODUCE SPECIES -SPECIFIC SCRAPIE INFECTIVITY AND AMYLOID PLAQUES. Journal of Neuropathology & Experimental Neurology. 49(3). 311–311. 11 indexed citations
18.
Scott, Michael, Dallas Foster, C. Mirenda, et al.. (1989). Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell. 59(5). 847–857. 557 indexed citations breakdown →
19.
Kempner, Ellis S., et al.. (1988). Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da. Virology. 164(2). 537–541. 113 indexed citations
20.
Gabizon, Ruth, et al.. (1988). Properties of scrapie prion protein liposomes.. Journal of Biological Chemistry. 263(10). 4950–4955. 57 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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