Miguel A. Pappolla

10.2k total citations · 2 hit papers
103 papers, 8.3k citations indexed

About

Miguel A. Pappolla is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Miguel A. Pappolla has authored 103 papers receiving a total of 8.3k indexed citations (citations by other indexed papers that have themselves been cited), including 61 papers in Physiology, 32 papers in Molecular Biology and 15 papers in Pharmacology. Recurrent topics in Miguel A. Pappolla's work include Alzheimer's disease research and treatments (53 papers), Cholinesterase and Neurodegenerative Diseases (13 papers) and Tryptophan and brain disorders (9 papers). Miguel A. Pappolla is often cited by papers focused on Alzheimer's disease research and treatments (53 papers), Cholinesterase and Neurodegenerative Diseases (13 papers) and Tryptophan and brain disorders (9 papers). Miguel A. Pappolla collaborates with scholars based in United States, Germany and Japan. Miguel A. Pappolla's co-authors include George Perry, Kumar Sambamurti, Mark A. Smith, Lorenzo M. Refolo, Keisuke Hirai, Burkhard Pöeggeler, Rosmarıa Omar, Karen Duff, Tara Bryant‐Thomas and Rawhi Omar and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Neuroscience.

In The Last Decade

Miguel A. Pappolla

102 papers receiving 8.1k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

2000 825 citations Lorenzo M. Refolo, Miguel A. Pappolla et al. Neurobiology of Disease profile →
RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer’s Disease

1999 614 citations George Perry, Miguel A. Pappolla et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Miguel A. Pappolla United States	42	4.7k	3.0k	1.2k	933	923	103	8.3k
Keisuke Hirai Japan	35	3.6k 0.7×	3.3k 1.1×	1.0k 0.8×	899 1.0×	535 0.6×	110	7.7k
Fernanda G. De Felice Brazil	55	6.5k 1.4×	3.5k 1.2×	1.5k 1.2×	2.2k 2.3×	500 0.5×	114	10.9k
Kumar Sambamurti United States	53	5.2k 1.1×	3.7k 1.2×	2.6k 2.1×	1.6k 1.7×	1.2k 1.3×	130	10.6k
Gemma Casadesús United States	55	4.7k 1.0×	3.8k 1.3×	1.2k 1.0×	1.6k 1.7×	262 0.3×	148	9.9k
Mercè Pallàs Spain	56	3.9k 0.8×	4.3k 1.4×	1.1k 0.8×	2.2k 2.3×	269 0.3×	315	10.9k
Inhee Mook‐Jung South Korea	64	4.9k 1.0×	4.6k 1.5×	1.1k 0.9×	1.7k 1.9×	353 0.4×	208	11.3k
Jin Fu China	34	3.1k 0.7×	3.2k 1.1×	3.1k 2.5×	1.2k 1.2×	880 1.0×	74	8.9k
Maria S. Santos Portugal	54	3.1k 0.7×	3.8k 1.3×	779 0.6×	1.1k 1.2×	481 0.5×	190	9.0k
Giulio Maria Pasinetti United States	75	7.0k 1.5×	6.2k 2.1×	2.3k 1.9×	2.6k 2.8×	597 0.6×	326	17.0k
Mikio Shoji Japan	55	7.0k 1.5×	5.5k 1.8×	1.4k 1.2×	2.7k 2.9×	481 0.5×	293	12.0k

Countries citing papers authored by Miguel A. Pappolla

Since Specialization

Citations

This map shows the geographic impact of Miguel A. Pappolla's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Miguel A. Pappolla with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Miguel A. Pappolla more than expected).

Fields of papers citing papers by Miguel A. Pappolla

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Miguel A. Pappolla. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Miguel A. Pappolla. The network helps show where Miguel A. Pappolla may publish in the future.

Co-authorship network of co-authors of Miguel A. Pappolla

This figure shows the co-authorship network connecting the top 25 collaborators of Miguel A. Pappolla. A scholar is included among the top collaborators of Miguel A. Pappolla based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Miguel A. Pappolla. Miguel A. Pappolla is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wu, Wenzhe, et al.. (2024). Viral Infections, Are They a Trigger and Risk Factor of Alzheimer’s Disease?. Pathogens. 13(3). 240–240. 11 indexed citations

Zhao, Yingxin, et al.. (2024). Discovery of novel metabolic biomarkers in blood serum for diagnosis of Alzheimer's disease. Journal of Alzheimer s Disease. 102(1). 237–253. 2 indexed citations

Pöeggeler, Burkhard, Sandeep Kumar Singh, Kumar Sambamurti, & Miguel A. Pappolla. (2023). Nitric Oxide as a Determinant of Human Longevity and Health Span. International Journal of Molecular Sciences. 24(19). 14533–14533. 6 indexed citations

Bharani, Krishna, Vasudevaraju Padmaraju, Nipun Chopra, et al.. (2015). Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease. Current Alzheimer Research. 12(1). 32–46. 239 indexed citations

Pinnix, Inga, Jorge Ghiso, Miguel A. Pappolla, & Kumar Sambamurti. (2013). Major Carboxyl Terminal Fragments Generated by γ-Secretase Processing of the Alzheimer Amyloid Precursor Are 50 and 51 Amino Acids Long. American Journal of Geriatric Psychiatry. 21(5). 474–483. 11 indexed citations

Sambamurti, Kumar, et al.. (2007). Amyloid Precursor Protein Metabolism in Retinal Degeneration. Investigative Ophthalmology & Visual Science. 48(13). 26–26. 1 indexed citations

Pappolla, Miguel A., Tara Bryant‐Thomas, David Herbert, et al.. (2003). Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology. Neurology. 61(2). 199–205. 258 indexed citations

Bendheim, Paul E., et al.. (2002). Development of indole-3-propionic acid (OXIGON™) for alzheimer’s disease. Journal of Molecular Neuroscience. 19(1-2). 213–217. 138 indexed citations

Pappolla, Miguel A., Rawhi Omar, Yau‐Jan Chyan, et al.. (2001). Induction of NADPH cytochrome P450 reductase by the Alzheimer β‐protein. Amyloid as a ‘foreign body’. Journal of Neurochemistry. 78(1). 121–128. 11 indexed citations

10.

Refolo, Lorenzo M., Miguel A. Pappolla, Brian Malester, et al.. (2000). Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model. Neurobiology of Disease. 7(4). 321–331. 825 indexed citations breakdown →

11.

Pappolla, Miguel A., Yau‐Jan Chyan, Peter Bozner, et al.. (1999). Alzheimer β protein mediated oxidative damage of mitochondrial DNA: Prevention by melatonin. Journal of Pineal Research. 27(4). 226–229. 74 indexed citations

12.

Vriesendorp, Francine J., et al.. (1996). Oral Administration of Type I Interferon Modulates the Course of Experimental Allergic Neuritis. Autoimmunity. 24(3). 157–165. 18 indexed citations

13.

Vriesendorp, Francine J., Robyn Flynn, Miguel A. Pappolla, & Carol Lee Koski. (1995). Complement depletion affects demyelination and inflammation in experimental allergic neuritis. Journal of Neuroimmunology. 58(2). 157–165. 39 indexed citations

14.

Pappolla, Miguel A., Kumar Sambamurti, Spiros Efthimiopoulos, et al.. (1995). Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins. Neuroscience Letters. 192(2). 105–108. 7 indexed citations

15.

Pappolla, Miguel A., Rosmarıa Omar, K. S. Kim, & Nikolaos K. Robakis. (1992). Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease.. PubMed Central. 140(3). 621–8. 302 indexed citations

16.

Holland, James A., Kirkwood A. Pritchard, Miguel A. Pappolla, et al.. (1990). Bradykinin induces superoxide anion release from human endothelial cells. Journal of Cellular Physiology. 143(1). 21–25. 127 indexed citations

17.

Pappolla, Miguel A., Rosmarıa Omar, Anne C. Andorn, et al.. (1989). Concurrent neuroborreliosis and alzheimer's disease: Analysis of the evidence. Human Pathology. 20(8). 753–757. 23 indexed citations

18.

Pappolla, Miguel A.. (1989). Image analysis microspectroscopy of senile plaque capillary amyloid in Alzheimer's disease. A preliminary study.. PubMed. 113(8). 866–71. 3 indexed citations

19.

Pappolla, Miguel A., et al.. (1989). The "normal" brain. "Abnormal" ubiquitinilated deposits highlight an age-related protein change.. PubMed. 135(4). 585–91. 43 indexed citations

20.

Pappolla, Miguel A. & Anne C. Andorn. (1987). Serum protein leakage in aged human brain and inhibition of ligand binding at alpha₂‐ adrenergic and cholinergic binding sites. Synapse. 1(1). 82–89. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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