Todd E. Golde

46.6k total citations · 11 hit papers
314 papers, 32.1k citations indexed

About

Todd E. Golde is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Todd E. Golde has authored 314 papers receiving a total of 32.1k indexed citations (citations by other indexed papers that have themselves been cited), including 193 papers in Physiology, 151 papers in Molecular Biology and 60 papers in Pharmacology. Recurrent topics in Todd E. Golde's work include Alzheimer's disease research and treatments (192 papers), Cholinesterase and Neurodegenerative Diseases (54 papers) and Neuroinflammation and Neurodegeneration Mechanisms (40 papers). Todd E. Golde is often cited by papers focused on Alzheimer's disease research and treatments (192 papers), Cholinesterase and Neurodegenerative Diseases (54 papers) and Neuroinflammation and Neurodegeneration Mechanisms (40 papers). Todd E. Golde collaborates with scholars based in United States, Germany and Canada. Todd E. Golde's co-authors include Steven G. Younkin, M. Paul Murphy, Pritam Das, Lucio Miele, Barbara A. Osborne, Edward H. Koo, Frank M. LaFerla, Christopher B. Eckman, Salvatore Oddo and Yama Akbari and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Todd E. Golde

313 papers receiving 31.5k citations

Hit Papers

Triple-Transgenic Model o... 1992 2026 2003 2014 2003 1992 1994 2001 1993 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles
    2003 3.3k citations M. Paul Murphy, Todd E. Golde et al. profile →
  2. Production of the Alzheimer Amyloid β Protein by Normal Proteolytic Processing
    1992 1.2k citations Todd E. Golde et al. Science profile →
  3. An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp 717 ) Mutants
    1994 1.2k citations Todd E. Golde et al. Science profile →
  4. A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
    2001 1.1k citations Sascha Weggen, Jason L. Eriksen et al. profile →
  5. Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor
    1993 749 citations Todd E. Golde et al. Science profile →
  6. γ-Secretase Cleavage and Nuclear Localization of ErbB-4 Receptor Tyrosine Kinase
    2001 710 citations M. Paul Murphy, Todd E. Golde et al. Science profile →
  7. Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives
    1992 625 citations Todd E. Golde et al. Science profile →
  8. The secretases: enzymes with therapeutic potential in Alzheimer disease
    2010 599 citations Bart De Strooper, Todd E. Golde et al. profile →
  9. NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo
    2003 502 citations Jason L. Eriksen, Sarah A. Sagi et al. Journal of Clinical Investigation profile →
  10. Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
    2009 484 citations Todd E. Golde et al. Proceedings of the National Academy of Sciences profile →
  11. Animal models of neurodegenerative diseases
    2018 388 citations Todd E. Golde et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Todd E. Golde 18.8k 14.2k 5.7k 5.4k 5.3k 314 32.1k
Takaomi C. Saido 19.6k 1.0× 16.3k 1.2× 8.2k 1.4× 6.6k 1.2× 4.5k 0.9× 504 36.1k
Sangram S. Sisodia 20.9k 1.1× 15.8k 1.1× 8.4k 1.5× 4.6k 0.8× 5.5k 1.0× 240 33.5k
Konrad Beyreuther 27.0k 1.4× 21.0k 1.5× 6.5k 1.1× 4.1k 0.8× 5.8k 1.1× 439 40.9k
Bart De Strooper 28.1k 1.5× 26.7k 1.9× 9.2k 1.6× 6.3k 1.2× 7.6k 1.4× 392 51.6k
Peter St George‐Hyslop 16.8k 0.9× 12.1k 0.9× 5.3k 0.9× 3.7k 0.7× 3.7k 0.7× 391 28.3k
Guojun Bu 14.8k 0.8× 12.1k 0.9× 4.6k 0.8× 6.8k 1.3× 2.4k 0.5× 336 30.8k
Lennart Mucke 20.8k 1.1× 12.4k 0.9× 13.4k 2.4× 9.1k 1.7× 4.8k 0.9× 172 38.9k
Matthias Staufenbiel 16.8k 0.9× 9.5k 0.7× 6.5k 1.1× 6.2k 1.2× 3.5k 0.7× 214 25.1k
Khalid Iqbal 21.9k 1.2× 15.0k 1.1× 7.6k 1.3× 5.2k 1.0× 5.1k 1.0× 375 32.8k
Allen D. Roses 17.9k 1.0× 14.4k 1.0× 5.7k 1.0× 3.8k 0.7× 3.5k 0.7× 357 34.7k

Countries citing papers authored by Todd E. Golde

Since Specialization
Citations

This map shows the geographic impact of Todd E. Golde's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Todd E. Golde with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Todd E. Golde more than expected).

Fields of papers citing papers by Todd E. Golde

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Todd E. Golde. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Todd E. Golde. The network helps show where Todd E. Golde may publish in the future.

Co-authorship network of co-authors of Todd E. Golde

This figure shows the co-authorship network connecting the top 25 collaborators of Todd E. Golde. A scholar is included among the top collaborators of Todd E. Golde based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Todd E. Golde. Todd E. Golde is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Dammer, Eric B., David A. Bennett, Richard C. Mohs, et al.. (2025). Plasma proteomic associations with Alzheimer’s disease endophenotypes. Nature Aging. 5(10). 2104–2124. 1 indexed citations
2.
Roemeling, Christina A. Von, Changlin Yang, Bently P. Doonan, et al.. (2024). Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade. Nature Communications. 15(1). 5871–5871. 5 indexed citations
3.
Croft, Cara L., Agnes L. Nishimura, Claire Troakes, et al.. (2024). Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection. Science Advances. 10(12). eadk9884–eadk9884. 13 indexed citations
4.
Trudler, Dorit, Kristopher L. Nazor, Yvonne S. Eisele, et al.. (2021). Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia. Proceedings of the National Academy of Sciences. 118(15). 98 indexed citations
5.
McFarland, Karen N., Carolina Wiesner, Awilda M. Rosario, et al.. (2021). Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo. Life Science Alliance. 4(7). e202101108–e202101108. 17 indexed citations
6.
Majumder, Samarpan, Judy S. Crabtree, Todd E. Golde, et al.. (2020). Targeting Notch in oncology: the path forward. Nature Reviews Drug Discovery. 20(2). 125–144. 197 indexed citations
7.
Lessard, Christian, Yingyue Zhou, Thomas B. Ladd, et al.. (2018). High‐affinity interactions and signal transduction between Aβ oligomers and TREM 2. EMBO Molecular Medicine. 10(11). 104 indexed citations
8.
Park, Hyo‐Jin, Yong Ran, Joo In Jung, et al.. (2015). The stress response neuropeptide CRF increases amyloid‐β production by regulating γ‐secretase activity. The EMBO Journal. 34(12). 1674–1686. 41 indexed citations
9.
Levites, Yona, Brian O’Nuallain, Tomáš Ondrejčák, et al.. (2015). A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo. PMC. 1 indexed citations
10.
Golde, Todd E., Wolfgang J. Streit, & Paramita Chakrabarty. (2013). Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease. Alzheimer s Research & Therapy. 5(3). 24–24. 28 indexed citations
11.
Harbut, Michael B., Bhumit A. Patel, Bryan K. S. Yeung, et al.. (2012). Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design. Proceedings of the National Academy of Sciences. 109(52). 21486–21491. 76 indexed citations
12.
Qi, Xiaoping, Jun Cai, Lutgarde Serneels, et al.. (2012). Inhibition of β-secretase Results in a Retinal Phenotype Involving Both the Vasculature and the RPE. Investigative Ophthalmology & Visual Science. 53(14). 1145–1145. 1 indexed citations
13.
Wang, Allan, Pritam Das, Robert C. Switzer, Todd E. Golde, & Joanna L. Jankowsky. (2011). Robust Amyloid Clearance in a Mouse Model of Alzheimer's Disease Provides Novel Insights into the Mechanism of Amyloid-β Immunotherapy. Journal of Neuroscience. 31(11). 4124–4136. 94 indexed citations
14.
Lo, Shelly S., Kathy S. Albain, Patricia A. Robinson, et al.. (2010). Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.. PubMed. 30(10). 3853–67. 119 indexed citations
15.
Rizzo, Paola, Clodia Osipo, Antonio Pannuti, et al.. (2009). Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer. Advances in Enzyme Regulation. 49(1). 134–141. 22 indexed citations
16.
Samon, Jeremy B., Ameya S. Champhekar, Lisa M. Minter, et al.. (2008). Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 112(5). 1813–1821. 159 indexed citations
17.
Osipo, Clodia, Payal T. Patel, Paola Rizzo, et al.. (2008). ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor. Oncogene. 27(37). 5019–5032. 170 indexed citations
18.
Osipo, Clodia, Todd E. Golde, Barbara A. Osborne, & Lucio Miele. (2007). Off the beaten pathway: the complex cross talk between Notch and NF-κB. Laboratory Investigation. 88(1). 11–17. 186 indexed citations
19.
Eriksen, Jason L., Sarah A. Sagi, Sascha Weggen, et al.. (2003). NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo. Journal of Clinical Investigation. 112(3). 440–449. 502 indexed citations breakdown →
20.
Murphy, M. Paul, et al.. (2001). γ-Secretase Cleavage and Nuclear Localization of ErbB-4 Receptor Tyrosine Kinase. Science. 294(5549). 2179–2181. 710 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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