Todd E. Golde

46.6k total citations · 11 hit papers
314 papers, 32.1k citations indexed

About

Todd E. Golde is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Todd E. Golde has authored 314 papers receiving a total of 32.1k indexed citations (citations by other indexed papers that have themselves been cited), including 193 papers in Physiology, 151 papers in Molecular Biology and 60 papers in Pharmacology. Recurrent topics in Todd E. Golde's work include Alzheimer's disease research and treatments (192 papers), Cholinesterase and Neurodegenerative Diseases (54 papers) and Neuroinflammation and Neurodegeneration Mechanisms (40 papers). Todd E. Golde is often cited by papers focused on Alzheimer's disease research and treatments (192 papers), Cholinesterase and Neurodegenerative Diseases (54 papers) and Neuroinflammation and Neurodegeneration Mechanisms (40 papers). Todd E. Golde collaborates with scholars based in United States, Germany and Canada. Todd E. Golde's co-authors include Steven G. Younkin, M. Paul Murphy, Pritam Das, Lucio Miele, Barbara A. Osborne, Edward H. Koo, Frank M. LaFerla, Christopher B. Eckman, Salvatore Oddo and Yama Akbari and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Todd E. Golde

313 papers receiving 31.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

2003 3.3k citations M. Paul Murphy, Todd E. Golde et al. profile →
Production of the Alzheimer Amyloid β Protein by Normal Proteolytic Processing

1992 1.2k citations Todd E. Golde et al. Science profile →
An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp ₇₁₇ ) Mutants

1994 1.2k citations Todd E. Golde et al. Science profile →
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

2001 1.1k citations Sascha Weggen, Jason L. Eriksen et al. profile →
Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor

1993 749 citations Todd E. Golde et al. Science profile →
γ-Secretase Cleavage and Nuclear Localization of ErbB-4 Receptor Tyrosine Kinase

2001 710 citations M. Paul Murphy, Todd E. Golde et al. Science profile →
Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1992 625 citations Todd E. Golde et al. Science profile →
The secretases: enzymes with therapeutic potential in Alzheimer disease

2010 599 citations Bart De Strooper, Todd E. Golde et al. profile →
NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo

2003 502 citations Jason L. Eriksen, Sarah A. Sagi et al. Journal of Clinical Investigation profile →
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

2009 484 citations Todd E. Golde, Dennis W. Dickson et al. Proceedings of the National Academy of Sciences profile →
Animal models of neurodegenerative diseases

2018 388 citations Todd E. Golde et al. profile →

Peers

Countries citing papers authored by Todd E. Golde

Since Specialization

Citations

This map shows the geographic impact of Todd E. Golde's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Todd E. Golde with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Todd E. Golde more than expected).

Fields of papers citing papers by Todd E. Golde

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Todd E. Golde. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Todd E. Golde. The network helps show where Todd E. Golde may publish in the future.

Co-authorship network of co-authors of Todd E. Golde

This figure shows the co-authorship network connecting the top 25 collaborators of Todd E. Golde. A scholar is included among the top collaborators of Todd E. Golde based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Todd E. Golde. Todd E. Golde is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Plasma proteomic associations with Alzheimer’s disease endophenotypes 2025 ·Nature Aging ·(unknown), Eric B. Dammer, (unknown), David A. Bennett, Richard C. Mohs, (unknown), John Dwyer, Chadwick M. Hales, Felicia C. Goldstein, Monica W. Parker, (unknown), Caroline M Watson, Todd E. Golde, Nicholas T. Seyfried, Blaine R. Roberts, Cecelia Manzanares, James J. Lah, Allan I. Levey, Erik C. B. Johnson	1
2	Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade 2024 ·Nature Communications ·Christina A. Von Roemeling, (unknown), (unknown), (unknown), Changlin Yang, (unknown), Bently P. Doonan, (unknown), (unknown), (unknown), Daniel Ryu, Adam Grippin, Hunter S. Futch, Yong Ran, Lan Hoang-Minh, (unknown), Todd E. Golde, Duane A. Mitchell	5
3	Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection 2024 ·Science Advances ·(unknown), (unknown), (unknown), (unknown), Cara L. Croft, Agnes L. Nishimura, (unknown), (unknown), Claire Troakes, Todd E. Golde, Beatriz Gomez Perez‐Nievas, Diane P. Hanger, Wendy Noble, María Jiménez-Sánchez	13
4	Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia 2021 ·Proceedings of the National Academy of Sciences ·Dorit Trudler, Kristopher L. Nazor, Yvonne S. Eisele, (unknown), Nima Dolatabadi, James Parker, Abdullah Sultan, Zhenyu Zhong, Marshall S. Goodwin, Yona Levites, Todd E. Golde, Jeffery W. Kelly, Michael R. Sierks, Nicholas J. Schork, Michael Karin, Rajesh Ambasudhan, Stuart A. Lipton	98
5	Targeting Notch in oncology: the path forward 2020 ·Nature Reviews Drug Discovery ·Samarpan Majumder, Judy S. Crabtree, Todd E. Golde, Lisa M. Minter, Barbara A. Osborne, Lucio Miele	197
6	High‐affinity interactions and signal transduction between Aβ oligomers and TREM 2 2018 ·EMBO Molecular Medicine ·Christian Lessard, (unknown), Yingyue Zhou, Thomas B. Ladd, Pedro E. Cruz, Yong Ran, Thomas E. Mahan, (unknown), David M. Holtzman, Jason D. Ulrich, Marco Colonna, Todd E. Golde	104
7	The stress response neuropeptide CRF increases amyloid‐β production by regulating γ‐secretase activity 2015 ·The EMBO Journal ·Hyo‐Jin Park, Yong Ran, Joo In Jung, Oliver Wendell Holmes, Ashleigh Price, Lisa Smithson, Carolina Ceballos‐Diaz, Chul Ju Han, Michael S. Wolfe, Yehia Daaka, Andrey E. Ryabinin, Seong‐Hun Kim, Richard L. Hauger, Todd E. Golde, Kevin M. Felsenstein	41
8	Re-Opening the Critical Window for Estrogen Therapy 2015 ·Journal of Neuroscience ·Linda A. Bean, Ashok Kumar, (unknown), (unknown), Awilda M. Rosario, Pedro E. Cruz, Todd E. Golde, Thomas C. Foster	44
9	Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design 2012 ·Proceedings of the National Academy of Sciences ·Michael B. Harbut, Bhumit A. Patel, Bryan K. S. Yeung, Case W. McNamara, A. Taylor Bright, (unknown), František Supek, Todd E. Golde, Elizabeth A. Winzeler, Thierry T. Diagana, Doron C. Greenbaum	76
10	Inhibition of β-secretase Results in a Retinal Phenotype Involving Both the Vasculature and the RPE 2012 ·Investigative Ophthalmology & Visual Science ·Xiaoping Qi, Jun Cai, (unknown), Lutgarde Serneels, Zhijuan Chen, Paul Säftig, Todd E. Golde, Maria B. Grant, Bart De Strooper, Michael E. Boulton	1
11	Robust Amyloid Clearance in a Mouse Model of Alzheimer's Disease Provides Novel Insights into the Mechanism of Amyloid-β Immunotherapy 2011 ·Journal of Neuroscience ·Allan Wang, Pritam Das, Robert C. Switzer, Todd E. Golde, Joanna L. Jankowsky	94
12	Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation. 2010 ·PubMed ·(unknown), Shelly S. Lo, Kathy S. Albain, Patricia A. Robinson, Prabha Rajan, Peter R. Strack, Todd E. Golde, Lucio Miele, Kimberly E. Foreman	119
13	IFN-γ Promotes Complement Expression and Attenuates Amyloid Plaque Deposition in Amyloid β Precursor Protein Transgenic Mice 2010 ·The Journal of Immunology ·Paramita Chakrabarty, Carolina Ceballos‐Diaz, Amanda Beccard, Christopher Janus, Dennis W. Dickson, Todd E. Golde, Pritam Das	156
14	Notch Regulates Cytolytic Effector Function in CD8+ T Cells 2009 ·The Journal of Immunology ·Ok Hyun Cho, Hyun Mu Shin, Lucio Miele, Todd E. Golde, Abdul H. Fauq, Lisa M. Minter, Barbara A. Osborne	115
15	Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells 2008 ·Blood ·Jeremy B. Samon, Ameya S. Champhekar, Lisa M. Minter, Janice C. Telfer, Lucio Miele, Abdul H. Fauq, Pritam Das, Todd E. Golde, Barbara A. Osborne	159
16	ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor 2008 ·Oncogene ·Clodia Osipo, Payal T. Patel, Paola Rizzo, Anthony G. Clementz, Liang Hao, Todd E. Golde, Lucio Miele	170
17	Off the beaten pathway: the complex cross talk between Notch and NF-κB 2007 ·Laboratory Investigation ·Clodia Osipo, Todd E. Golde, Barbara A. Osborne, Lucio Miele	186
18	NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo breakdown → 2003 ·Journal of Clinical Investigation ·Jason L. Eriksen, Sarah A. Sagi, (unknown), Sascha Weggen, Pritam Das, (unknown), Victor Ozols, (unknown), Kenton H. Zavitz, Edward H. Koo, Todd E. Golde	502
19	TCR-Mediated Notch Signaling Regulates Proliferation and IFN-γ Production in Peripheral T Cells 2003 ·The Journal of Immunology ·Tanapat Palaga, Lucio Miele, Todd E. Golde, Barbara A. Osborne	198
20	γ-Secretase Cleavage and Nuclear Localization of ErbB-4 Receptor Tyrosine Kinase breakdown → 2001 ·Science ·(unknown), M. Paul Murphy, Todd E. Golde, Graham Carpenter	710

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact