Frank M. LaFerla

55.8k total citations · 9 hit papers
248 papers, 36.7k citations indexed

About

Frank M. LaFerla is a scholar working on Physiology, Cellular and Molecular Neuroscience and Molecular Biology. According to data from OpenAlex, Frank M. LaFerla has authored 248 papers receiving a total of 36.7k indexed citations (citations by other indexed papers that have themselves been cited), including 196 papers in Physiology, 85 papers in Cellular and Molecular Neuroscience and 84 papers in Molecular Biology. Recurrent topics in Frank M. LaFerla's work include Alzheimer's disease research and treatments (192 papers), Cholinesterase and Neurodegenerative Diseases (51 papers) and Neuroscience and Neuropharmacology Research (47 papers). Frank M. LaFerla is often cited by papers focused on Alzheimer's disease research and treatments (192 papers), Cholinesterase and Neurodegenerative Diseases (51 papers) and Neuroscience and Neuropharmacology Research (47 papers). Frank M. LaFerla collaborates with scholars based in United States, Spain and Canada. Frank M. LaFerla's co-authors include Salvatore Oddo, Henry Querfurth, Kim N. Green, Antonella Caccamo, Masashi Kitazawa, Lauren M. Billings, Mark P. Mattson, Mathew Blurton‐Jones, Yama Akbari and James L. McGaugh and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Frank M. LaFerla

245 papers receiving 36.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Alzheimer's Disease

2010 3.7k citations Frank M. LaFerla et al. profile →
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

2003 3.3k citations Frank M. LaFerla et al. Neuron profile →
Intracellular amyloid-β in Alzheimer's disease

2007 1.6k citations Frank M. LaFerla, Kim N. Green et al. profile →
Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice

2005 1.0k citations Kim N. Green, Frank M. LaFerla et al. Neuron profile →
Calcium dyshomeostasis and intracellular signalling in alzheimer's disease

2002 821 citations Frank M. LaFerla profile →
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

2009 678 citations Mathew Blurton‐Jones, Masashi Kitazawa et al. Proceedings of the National Academy of Sciences profile →
Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome

2004 615 citations Frank M. LaFerla et al. Neuron profile →
Lipopolysaccharide-Induced Inflammation Exacerbates Tau Pathology by a Cyclin-Dependent Kinase 5-Mediated Pathway in a Transgenic Model of Alzheimer's Disease

2005 580 citations Masashi Kitazawa, Kim N. Green et al. Journal of Neuroscience profile →
Glucocorticoids Increase Amyloid-β and Tau Pathology in a Mouse Model of Alzheimer’s Disease

2006 521 citations Kim N. Green, Frank M. LaFerla et al. Journal of Neuroscience profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Frank M. LaFerla United States	97	23.2k	13.1k	10.1k	8.0k	6.3k	248	36.7k
Lennart Mucke United States	97	20.8k 0.9×	12.4k 1.0×	13.4k 1.3×	9.1k 1.1×	4.8k 0.8×	172	38.9k
Takaomi C. Saido Japan	98	19.6k 0.8×	16.3k 1.3×	8.2k 0.8×	6.6k 0.8×	4.5k 0.7×	504	36.1k
Sangram S. Sisodia United States	91	20.9k 0.9×	15.8k 1.2×	8.4k 0.8×	4.6k 0.6×	5.5k 0.9×	240	33.5k
Khalid Iqbal United States	95	21.9k 0.9×	15.0k 1.1×	7.6k 0.7×	5.2k 0.7×	5.1k 0.8×	375	32.8k
Todd E. Golde United States	94	18.8k 0.8×	14.2k 1.1×	5.7k 0.6×	5.4k 0.7×	5.3k 0.8×	314	32.1k
Bart De Strooper Belgium	122	28.1k 1.2×	26.7k 2.0×	9.2k 0.9×	6.3k 0.8×	7.6k 1.2×	392	51.6k
Dominic M. Walsh United States	78	26.7k 1.2×	15.0k 1.1×	8.2k 0.8×	5.5k 0.7×	6.6k 1.0×	162	33.8k
Karen Duff United States	89	18.0k 0.8×	10.9k 0.8×	9.6k 0.9×	5.2k 0.7×	4.1k 0.6×	236	29.5k
Matthias Staufenbiel Switzerland	85	16.8k 0.7×	9.5k 0.7×	6.5k 0.6×	6.2k 0.8×	3.5k 0.6×	214	25.1k
Inge Grundke‐Iqbal United States	89	21.7k 0.9×	15.2k 1.2×	7.5k 0.7×	4.9k 0.6×	4.9k 0.8×	280	31.7k

Countries citing papers authored by Frank M. LaFerla

Since Specialization

Citations

This map shows the geographic impact of Frank M. LaFerla's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank M. LaFerla with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank M. LaFerla more than expected).

Fields of papers citing papers by Frank M. LaFerla

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank M. LaFerla. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank M. LaFerla. The network helps show where Frank M. LaFerla may publish in the future.

Co-authorship network of co-authors of Frank M. LaFerla

This figure shows the co-authorship network connecting the top 25 collaborators of Frank M. LaFerla. A scholar is included among the top collaborators of Frank M. LaFerla based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank M. LaFerla. Frank M. LaFerla is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Huat, Tee Jong, Judith Camats‐Perna, Estella A. Newcombe, et al.. (2024). The impact of astrocytic NF-κB on healthy and Alzheimer’s disease brains. Scientific Reports. 14(1). 14305–14305. 17 indexed citations

Trujillo‐Estrada, Laura, et al.. (2023). VISCERAL ADIPOSE TISSUE TRIGGERS TAU PATHOGENESIS IN TRANSGENIC MICE TROUGH CDK5/P25 PATHWAY. IBRO Neuroscience Reports. 15. S370–S371. 1 indexed citations

Milinkeviciute, Giedre, Celia Da Cunha, Jonathan Neumann, et al.. (2023). A CLU/APOJ GWAS AD risk variant suppresses the astrocytic response to plaques and reduces axonal and neuritic damage in 5xFAD mice. Alzheimer s & Dementia. 19(S12). 1 indexed citations

Castillo, Erika, Julio Leon, Nona Abolhassani, et al.. (2021). Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation. Scientific Reports. 11(1). 18377–18377. 4 indexed citations

Oblak, Adrian L., Stefânia Forner, Paul R. Territo, et al.. (2020). Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD. Alzheimer s & Dementia Translational Research & Clinical Interventions. 6(1). e12110–e12110. 62 indexed citations

Martini, Alessandra Cadete, Ángela Gómez-Arboledas, Stefânia Forner, et al.. (2019). Amyloid-beta impairs TOM1-mediated IL-1R1 signaling. Proceedings of the National Academy of Sciences. 116(42). 21198–21206. 22 indexed citations

Lee, Siyoung, Bo‐Ryoung Choi, Jisung Kim, et al.. (2018). Sulforaphane Upregulates the Heat Shock Protein Co‐Chaperone CHIP and Clears Amyloid‐β and Tau in a Mouse Model of Alzheimer's Disease. Molecular Nutrition & Food Research. 62(12). e1800240–e1800240. 61 indexed citations

Jeugd, Ann Van der, Arnaldo Parra‐Damas, Tariq Ahmed, et al.. (2018). Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice. Scientific Reports. 8(1). 6431–6431. 42 indexed citations

Frontiñán-Rubio, Javier, Juan R. Peinado, Frank M. LaFerla, et al.. (2018). Sex-dependent co-occurrence of hypoxia and β-amyloid plaques in hippocampus and entorhinal cortex is reversed by long-term treatment with ubiquinol and ascorbic acid in the 3 × Tg-AD mouse model of Alzheimer's disease. Molecular and Cellular Neuroscience. 92. 67–81. 18 indexed citations

10.

Kim, Jisung, Jisung Kim, Siyoung Lee, et al.. (2016). Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways. Molecular Nutrition & Food Research. 61(2). 58 indexed citations

11.

Manuel, Iván, Laura Lombardero, Frank M. LaFerla, Lydia Giménez‐Llort, & Rafael Rodríguez‐Puertas. (2016). Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer’s disease. Neuroscience. 329. 284–293. 18 indexed citations

12.

Hunsberger, Joshua, Mahendra S. Rao, Joanne Kurtzberg, et al.. (2015). Accelerating stem cell trials for Alzheimer's disease. The Lancet Neurology. 15(2). 219–230. 75 indexed citations

13.

Baglietto‐Vargas, David, Yuncai Chen, Dongjin Suh, et al.. (2015). Short‐term modern life‐like stress exacerbates Aβ‐pathology and synapse loss in 3xTg‐AD mice. Journal of Neurochemistry. 134(5). 915–926. 71 indexed citations

14.

Yeung, Stephen T., et al.. (2013). Impact of hippocampal neuronal ablation on neurogenesis and cognition in the aged brain. Neuroscience. 259. 214–222. 32 indexed citations

15.

Baglietto‐Vargas, David, Rodrigo Medeiros, Hilda Martínez‐Coria, Frank M. LaFerla, & Kim N. Green. (2013). Mifepristone Alters Amyloid Precursor Protein Processing to Preclude Amyloid Beta and Also Reduces Tau Pathology. Biological Psychiatry. 74(5). 357–366. 82 indexed citations

16.

Dickinson, George D., et al.. (2012). Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: Implications for lysosomal function. Brain Research. 1489. 8–16. 42 indexed citations

17.

Freude, Kristine, et al.. (2011). Soluble Amyloid Precursor Protein Induces Rapid Neural Differentiation of Human Embryonic Stem Cells. Journal of Biological Chemistry. 286(27). 24264–24274. 62 indexed citations

18.

Koike, Maya A., Kim N. Green, Mathew Blurton‐Jones, & Frank M. LaFerla. (2010). Oligemic Hypoperfusion Differentially Affects Tau and Amyloid-β. American Journal Of Pathology. 177(1). 300–310. 108 indexed citations

19.

Green, Kim N. & Frank M. LaFerla. (2008). Linking Calcium to Aβ and Alzheimer's Disease. Neuron. 59(2). 190–194. 270 indexed citations

20.

Green, Kim N., Joan S. Steffan, Hilda Martínez‐Coria, et al.. (2008). Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau. Journal of Neuroscience. 28(45). 11500–11510. 319 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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