Frank M. LaFerla

55.8k citations

248 papers · 36.7k indexed · 9 hit papers · h-index 97

Physiology top 0.01%
Molecular Biology top 0.2%
Cellular and Molecular Neuroscience top 0.05%
Neurology top 0.01%
Pharmacology top 0.02%

Co-authors: Salvatore Oddo Henry Querfurth Kim N. Green Antonella Caccamo Masashi Kitazawa Lauren M. Billings Mark P. Mattson Mathew Blurton‐Jones
Topics: Alzheimer's disease research and treatments (192 papers)Cholinesterase and Neurodegenerative Diseases (51 papers)Neuroscience and Neuropharmacology Research (47 papers)
Cited by: Biological Psychiatry Neurology Physiology
Journals: New England Journal of Medicine Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: United States Spain Canada

In The Last Decade

Frank M. LaFerla

245 papers receiving 36.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Alzheimer's Disease

2010 3.7k citations Frank M. LaFerla et al. profile →
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

2003 3.3k citations Salvatore Oddo, Frank M. LaFerla et al. Neuron profile →
Intracellular amyloid-β in Alzheimer's disease

2007 1.6k citations Frank M. LaFerla, Kim N. Green et al. profile →
Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice

2005 1.0k citations Salvatore Oddo, Kim N. Green et al. Neuron profile →
Calcium dyshomeostasis and intracellular signalling in alzheimer's disease

2002 821 citations Frank M. LaFerla profile →
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

2009 678 citations Mathew Blurton‐Jones, Masashi Kitazawa et al. Proceedings of the National Academy of Sciences profile →
Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome

2004 615 citations Salvatore Oddo, Frank M. LaFerla et al. Neuron profile →
Lipopolysaccharide-Induced Inflammation Exacerbates Tau Pathology by a Cyclin-Dependent Kinase 5-Mediated Pathway in a Transgenic Model of Alzheimer's Disease

2005 580 citations Masashi Kitazawa, Salvatore Oddo et al. Journal of Neuroscience profile →
Glucocorticoids Increase Amyloid-β and Tau Pathology in a Mouse Model of Alzheimer’s Disease

2006 521 citations Kim N. Green, Frank M. LaFerla et al. Journal of Neuroscience profile →

Peers

Countries citing papers authored by Frank M. LaFerla

Since Specialization

Citations

This map shows the geographic impact of Frank M. LaFerla's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank M. LaFerla with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank M. LaFerla more than expected).

Fields of papers citing papers by Frank M. LaFerla

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank M. LaFerla. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank M. LaFerla. The network helps show where Frank M. LaFerla may publish in the future.

Co-authorship network of co-authors of Frank M. LaFerla

This figure shows the co-authorship network connecting the top 25 collaborators of Frank M. LaFerla. A scholar is included among the top collaborators of Frank M. LaFerla based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank M. LaFerla. Frank M. LaFerla is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A CLU/APOJ GWAS AD risk variant suppresses the astrocytic response to plaques and reduces axonal and neuritic damage in 5xFAD mice 2023 ·Alzheimer s & Dementia ·Giedre Milinkeviciute,(unknown),Celia Da Cunha,(unknown),(unknown),Jonathan Neumann,(unknown),Shimako Kawauchi,Andrea J. Tenner,Frank M. LaFerla,Grant R. MacGregor,Kim N. Green	1
2	Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation 2021 ·Scientific Reports ·Erika Castillo,Julio Leon,(unknown),Nona Abolhassani,Naoki Haruyama,Takashi Saito,Takaomi C. Saido,Masaaki Hokama,Toru Iwaki,Tomoyuki Ohara,Toshiharu Ninomiya,Yutaka Kiyohara,Kunihiko Sakumi,Frank M. LaFerla,Yusaku Nakabeppu	4
3	miR‐181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer’s disease 2020 ·Aging Cell ·Carlos J. Rodríguez‐Ortiz,G. Aleph Prieto,Alessandra Cadete Martini,Stefânia Forner,Laura Trujillo‐Estrada,Frank M. LaFerla,David Baglietto‐Vargas,Carl W. Cotman,Masashi Kitazawa	50
4	Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD 2020 ·Alzheimer s & Dementia Translational Research & Clinical Interventions ·Adrian L. Oblak,Stefânia Forner,Paul R. Territo,Michael Sasner,Gregory W. Carter,Gareth R. Howell,Stacey J. Sukoff Rizzo,Benjamin A. Logsdon,Lara M. Mangravite,A Mortazavi,David Baglietto‐Vargas,Kim N. Green,Grant R. MacGregor,Marcelo A. Wood,Andrea J. Tenner,Frank M. LaFerla,Bruce T. Lamb,(unknown)	62
5	Amyloid-beta impairs TOM1-mediated IL-1R1 signaling 2019 ·Proceedings of the National Academy of Sciences ·Alessandra Cadete Martini,Ángela Gómez-Arboledas,Stefânia Forner,Carlos J. Rodríguez‐Ortiz,Amanda McQuade,Emma Danhash,Jimmy Phan,Dominic I. Javonillo,(unknown),(unknown),Laura Trujillo‐Estrada,Celia Da Cunha,Rahasson R. Ager,José Carlos Dávila,Masashi Kitazawa,Mathew Blurton‐Jones,Antonia Gutiérrez,David Baglietto‐Vargas,Rodrigo Medeiros,Frank M. LaFerla	22
6	Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice 2018 ·Scientific Reports ·Ann Van der Jeugd,Arnaldo Parra‐Damas,(unknown),(unknown),Tariq Ahmed,Frank M. LaFerla,Lydia Giménez‐Llort,Rudi D’Hooge,Carlos A. Saura	42
7	Sex-dependent co-occurrence of hypoxia and β-amyloid plaques in hippocampus and entorhinal cortex is reversed by long-term treatment with ubiquinol and ascorbic acid in the 3 × Tg-AD mouse model of Alzheimer's disease 2018 ·Molecular and Cellular Neuroscience ·Javier Frontiñán-Rubio,(unknown),Juan R. Peinado,Frank M. LaFerla,Lydia Giménez‐Llort,Mario Durán‐Prado,Francisco J. Alcaı́n	18
8	Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation 2017 ·Scientific Reports ·Erika Castillo,Julio Leon,(unknown),Nona Abolhassani,Naoki Haruyama,Takashi Saito,Takaomi C. Saido,Masaaki Hokama,Toru Iwaki,Tomoyuki Ohara,Toshiharu Ninomiya,Yutaka Kiyohara,Kunihiko Sakumi,Frank M. LaFerla,Yusaku Nakabeppu	113
9	Short‐term modern life‐like stress exacerbates Aβ‐pathology and synapse loss in 3xTg‐AD mice 2015 ·Journal of Neurochemistry ·David Baglietto‐Vargas,Yuncai Chen,Dongjin Suh,Rahasson R. Ager,Carlos J. Rodríguez‐Ortiz,Rodrigo Medeiros,Kristoffer Myczek,Kim N. Green,Tallie Z. Baram,Frank M. LaFerla	71
10	AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer's Disease 2015 ·Neurodegenerative Diseases ·Abraham Fisher,Ilya Bezprozvanny,Lili Wu,Daniel A. Ryskamp,Nira Bar-Ner,Niva Natan,Rachel Brandeis,(unknown),(unknown),Eytan Gershonov,Frank M. LaFerla,Rodrigo Medeiros	65
11	Mifepristone Alters Amyloid Precursor Protein Processing to Preclude Amyloid Beta and Also Reduces Tau Pathology 2013 ·Biological Psychiatry ·David Baglietto‐Vargas,Rodrigo Medeiros,Hilda Martínez‐Coria,Frank M. LaFerla,Kim N. Green	82
12	Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: Implications for lysosomal function 2012 ·Brain Research ·(unknown),George D. Dickinson,(unknown),Ken C. Walls,Kim N. Green,Frank M. LaFerla	42
13	Soluble Amyloid Precursor Protein Induces Rapid Neural Differentiation of Human Embryonic Stem Cells 2011 ·Journal of Biological Chemistry ·Kristine Freude,(unknown),Joy Davis,Frank M. LaFerla,Mathew Blurton‐Jones	62
14	Treatment with a C5aR Antagonist Decreases Pathology and Enhances Behavioral Performance in Murine Models of Alzheimer’s Disease 2009 ·The Journal of Immunology ·María Isabel Fonseca,Rahasson R. Ager,(unknown),(unknown),Sam D. Sanderson,Frank M. LaFerla,Stephen M. Taylor,Trent M. Woodruff,Andrea J. Tenner	232
15	Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau 2008 ·Journal of Neuroscience ·Kim N. Green,Joan S. Steffan,Hilda Martínez‐Coria,Xuemin Sun,Steven S. Schreiber,Leslie M. Thompson,Frank M. LaFerla	319
16	Linking Calcium to Aβ and Alzheimer's Disease 2008 ·Neuron ·Kim N. Green,Frank M. LaFerla	270
17	Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology 2004 ·Journal of Clinical Investigation ·Robert A. Rissman,Wayne W. Poon,Mathew Blurton‐Jones,Salvatore Oddo,Reidun Torp,Michael P. Vitek,Frank M. LaFerla,Troy T. Rohn,Carl W. Cotman	405
18	Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia 2004 ·Journal of Clinical Investigation ·Vikram G. Shakkottai,(unknown),Salvatore Oddo,Claudia A. Sailer,(unknown),George A. Gutman,Michael E. Barish,Frank M. LaFerla,K. George Chandy	97
19	Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia 2004 ·Journal of Clinical Investigation ·Vikram G. Shakkottai,(unknown),Salvatore Oddo,Claudia A. Sailer,Hans‐Günther Knaus,George A. Gutman,Michael E. Barish,Frank M. LaFerla,K. George Chandy	43
20	Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology 2004 ·Journal of Clinical Investigation ·Robert A. Rissman,Wayne W. Poon,Mathew Blurton‐Jones,Salvatore Oddo,Reidun Torp,Michael P. Vitek,Frank M. LaFerla,Troy T. Rohn,Carl W. Cotman	365

About Frank M. LaFerla

Frank M. LaFerla is a scholar working on Biological Psychiatry, Physiology and Neurology, having authored 248 papers that have together received 36.7k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (192 papers), Cholinesterase and Neurodegenerative Diseases (51 papers) and Neuroscience and Neuropharmacology Research (47 papers). The work is most often cited by research in Biological Psychiatry (3.4k citations), Neurology (8.0k citations) and Physiology (23.2k citations). Frank M. LaFerla has collaborated with scholars based in United States, Spain and Canada. Frequent co-authors include Salvatore Oddo, Henry Querfurth, Kim N. Green, Antonella Caccamo, Masashi Kitazawa, Lauren M. Billings, Mark P. Mattson, Mathew Blurton‐Jones, Yama Akbari and James L. McGaugh. Their work appears in journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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