Peter St George‐Hyslop

80.6k total citations · 5 hit papers
391 papers, 28.3k citations indexed

About

Peter St George‐Hyslop is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Peter St George‐Hyslop has authored 391 papers receiving a total of 28.3k indexed citations (citations by other indexed papers that have themselves been cited), including 258 papers in Physiology, 183 papers in Molecular Biology and 60 papers in Cellular and Molecular Neuroscience. Recurrent topics in Peter St George‐Hyslop's work include Alzheimer's disease research and treatments (255 papers), Cholinesterase and Neurodegenerative Diseases (47 papers) and Prion Diseases and Protein Misfolding (40 papers). Peter St George‐Hyslop is often cited by papers focused on Alzheimer's disease research and treatments (255 papers), Cholinesterase and Neurodegenerative Diseases (47 papers) and Prion Diseases and Protein Misfolding (40 papers). Peter St George‐Hyslop collaborates with scholars based in Canada, United States and United Kingdom. Peter St George‐Hyslop's co-authors include James F. Gusella, Ekaterina Rogaeva, Paul E. Fraser, Allen D. Roses, Sangram S. Sisodia, Ann M. Saunders, Dmitry Goldgaber, Barbara J. Crain, Toshitaka Kawarai and Mark J. Alberts and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Peter St George‐Hyslop

386 papers receiving 27.6k citations

Hit Papers

Association of apolipoprotein E allele ϵ4 with late‐onset... 1987 2026 2000 2013 1993 1987 2000 2004 2021 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease
    1993 3.0k citations Peter St George‐Hyslop et al. profile →
  2. Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus
    1987 1.3k citations Peter St George‐Hyslop et al. profile →
  3. Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
    2000 1.2k citations Paul M. Mathews, Stephen D. Schmidt et al. Nature profile →
  4. Functional variants of OCTN cation transporter genes are associated with Crohn disease
    2004 596 citations Peter St George‐Hyslop et al. Nature Genetics profile →
  5. Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
    2021 339 citations Georg Krainer, Timothy J. Welsh et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Peter St George‐Hyslop Canada 83 16.8k 12.1k 5.3k 4.7k 3.7k 391 28.3k
Alison Goate United States 91 15.0k 0.9× 12.2k 1.0× 5.4k 1.0× 3.2k 0.7× 4.8k 1.3× 431 30.4k
Allen D. Roses United States 77 17.9k 1.1× 14.4k 1.2× 5.7k 1.1× 3.8k 0.8× 3.8k 1.0× 357 34.7k
Karen Duff United States 89 18.0k 1.1× 10.9k 0.9× 9.6k 1.8× 4.5k 1.0× 5.2k 1.4× 236 29.5k
Khalid Iqbal United States 95 21.9k 1.3× 15.0k 1.2× 7.6k 1.4× 3.1k 0.7× 5.2k 1.4× 375 32.8k
Todd E. Golde United States 94 18.8k 1.1× 14.2k 1.2× 5.7k 1.1× 3.2k 0.7× 5.4k 1.4× 314 32.1k
Inge Grundke‐Iqbal United States 89 21.7k 1.3× 15.2k 1.2× 7.5k 1.4× 3.2k 0.7× 4.9k 1.3× 280 31.7k
Jeffery M. Vance United States 70 10.3k 0.6× 12.8k 1.1× 7.0k 1.3× 4.2k 0.9× 3.6k 1.0× 298 29.0k
Guojun Bu United States 101 14.8k 0.9× 12.1k 1.0× 4.6k 0.9× 2.4k 0.5× 6.8k 1.8× 336 30.8k
Sangram S. Sisodia United States 91 20.9k 1.2× 15.8k 1.3× 8.4k 1.6× 4.3k 0.9× 4.6k 1.2× 240 33.5k
Warren J. Strittmatter United States 53 14.8k 0.9× 10.7k 0.9× 5.2k 1.0× 2.6k 0.6× 2.9k 0.8× 107 25.3k

Countries citing papers authored by Peter St George‐Hyslop

Since Specialization
Citations

This map shows the geographic impact of Peter St George‐Hyslop's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter St George‐Hyslop with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter St George‐Hyslop more than expected).

Fields of papers citing papers by Peter St George‐Hyslop

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter St George‐Hyslop. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter St George‐Hyslop. The network helps show where Peter St George‐Hyslop may publish in the future.

Co-authorship network of co-authors of Peter St George‐Hyslop

This figure shows the co-authorship network connecting the top 25 collaborators of Peter St George‐Hyslop. A scholar is included among the top collaborators of Peter St George‐Hyslop based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Peter St George‐Hyslop. Peter St George‐Hyslop is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Haage, Verena, Charles C. White, Ronak Patel, et al.. (2025). HDAC inhibitors engage MITF and the disease-associated microglia signature to enhance amyloid β uptake. Brain Behavior and Immunity. 129. 279–293. 1 indexed citations
2.
Tartwijk, Francesca W. van, Ioanna Mela, Maximilian AH Jakobs, et al.. (2024). Mutation of the ALS-/FTD-Associated RNA-Binding Protein FUS Affects Axonal Development. Journal of Neuroscience. 44(27). e2148232024–e2148232024. 1 indexed citations
3.
Poon, Chi Him, Zhigang Zhang, Ming Yue, et al.. (2023). MicroRNA‐128 suppresses tau phosphorylation and reduces amyloid‐beta accumulation by inhibiting the expression of GSK3β, APPBP2, and mTOR in Alzheimer's disease. CNS Neuroscience & Therapeutics. 29(7). 1848–1864. 20 indexed citations
4.
Volkmar, Norbert, Christian M. Gawden‐Bone, James C. Williamson, et al.. (2022). Regulation of membrane fluidity by RNF145 ‐triggered degradation of the lipid hydrolase ADIPOR2. The EMBO Journal. 41(19). e110777–e110777. 14 indexed citations
5.
Arter, William E., Runzhang Qi, Nadia A. Erkamp, et al.. (2022). Biomolecular condensate phase diagrams with a combinatorial microdroplet platform. Nature Communications. 13(1). 53 indexed citations
6.
Audrain, Mickaël, Jean‐Vianney Haure‐Mirande, Minghui Wang, et al.. (2018). Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau. Molecular Psychiatry. 24(9). 1383–1397. 52 indexed citations
7.
Reitz, Christiane, Giuseppe Tosto, Badri N. Vardarajan, et al.. (2013). Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). Translational Psychiatry. 3(5). e256–e256. 58 indexed citations
8.
Pettersen, Jacqueline A., Fuqiang Gao, Gregory M. Szilagyi, et al.. (2008). Microbleed Topography, Leukoaraiosis, and Cognition in Probable Alzheimer Disease From the Sunnybrook Dementia Study. Archives of Neurology. 65(6). 790–5. 214 indexed citations
9.
Chen, Fusheng, Hiroshi Hasegawa, Gerold Schmitt‐Ulms, et al.. (2006). TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity. Nature. 440(7088). 1208–1212. 240 indexed citations
10.
Nakaya, Yoshifumi, T. Yamane, Hirohisa Shiraishi, et al.. (2005). Random Mutagenesis of Presenilin-1 Identifies Novel Mutants Exclusively Generating Long Amyloid β-Peptides. Journal of Biological Chemistry. 280(19). 19070–19077. 38 indexed citations
11.
Ikeda, Masaki, Toshitaka Kawarai, Takeshi Kawarabayashi, et al.. (2005). Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic Mice. American Journal Of Pathology. 166(2). 521–531. 88 indexed citations
12.
Orlacchio, Antonio, Toshitaka Kawarai, Mario Polidoro, et al.. (2004). Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene. Neuroscience Letters. 363(1). 49–53. 4 indexed citations
13.
Sato, Christine, Angharad R. Morgan, Anthony E. Lang, et al.. (2004). Analysis of the glucocerebrosidase gene in Parkinson's disease. Movement Disorders. 20(3). 367–370. 91 indexed citations
14.
Gandy, Sam, Cynthia A. Lemere, Frank L. Heppner, et al.. (2004). Alzheimer Aβ Vaccination of Rhesus Monkeys (Macaca Mulatta). Alzheimer Disease & Associated Disorders. 18(1). 44–46. 23 indexed citations
15.
Rozmahel, Richard, Howard T.J. Mount, Fusheng Chen, et al.. (2002). Alleles at the Nicastrin locus modify presenilin 1- deficiency phenotype. Proceedings of the National Academy of Sciences. 99(22). 14452–14457. 15 indexed citations
16.
Orlacchio, Antonio, Toshitaka Kawarai, Alessandro Stefani, et al.. (2002). Association study of the 5-hydroxytryptamine6 receptor gene in Alzheimer's disease. Neuroscience Letters. 325(1). 13–16. 18 indexed citations
17.
Watnick, Terry, Kairong Wang, Yan Liang, et al.. (2000). Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations. Nature Genetics. 25(2). 143–144. 102 indexed citations
18.
Katayama, Taiichi, Kazunori Imaizumi, Naoya Sato, et al.. (1999). Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nature Cell Biology. 1(8). 479–485. 449 indexed citations
19.
Lippa, Carol F., Hideo Fujiwara, David M. A. Mann, et al.. (1998). Lewy Bodies Contain Altered α-Synuclein in Brains of Many Familial Alzheimer's Disease Patients with Mutations in Presenilin and Amyloid Precursor Protein Genes. American Journal Of Pathology. 153(5). 1365–1370. 429 indexed citations
20.
George‐Hyslop, Peter St, Georges Lévesque, Gang Yu, et al.. (1997). Biology and genetics of the presenilin proteins associated with alzheimer disease. The FASEB Journal. 11(9). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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