Guojun Bu

46.4k total citations · 13 hit papers
336 papers, 30.8k citations indexed

About

Guojun Bu is a scholar working on Physiology, Molecular Biology and Cell Biology. According to data from OpenAlex, Guojun Bu has authored 336 papers receiving a total of 30.8k indexed citations (citations by other indexed papers that have themselves been cited), including 171 papers in Physiology, 150 papers in Molecular Biology and 68 papers in Cell Biology. Recurrent topics in Guojun Bu's work include Alzheimer's disease research and treatments (162 papers), Neuroinflammation and Neurodegeneration Mechanisms (44 papers) and Protease and Inhibitor Mechanisms (41 papers). Guojun Bu is often cited by papers focused on Alzheimer's disease research and treatments (162 papers), Neuroinflammation and Neurodegeneration Mechanisms (44 papers) and Protease and Inhibitor Mechanisms (41 papers). Guojun Bu collaborates with scholars based in United States, China and Japan. Guojun Bu's co-authors include Chia‐Chen Liu, Takahisa Kanekiyo, Huaxi Xu, David M. Holtzman, Alan L. Schwartz, Na Zhao, Mitsuru Shinohara, Yu Yamazaki, Yonghe Li and Yun‐wu Zhang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Circulation.

In The Last Decade

Guojun Bu

331 papers receiving 30.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

2013 2.4k citations Chia‐Chen Liu, Takahisa Kanekiyo et al. Nature Reviews Neurology profile →
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

2009 857 citations Guojun Bu profile →
Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

2019 848 citations Yu Yamazaki, Na Zhao et al. Nature Reviews Neurology profile →
Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

2012 594 citations Guojun Bu et al. profile →
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

2018 519 citations Guojun Bu, Huaxi Xu et al. Neuron profile →
ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

2014 458 citations Takahisa Kanekiyo, Huaxi Xu et al. Neuron profile →
ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

2013 433 citations Guojun Bu et al. profile →
ApoE in Alzheimer’s disease: pathophysiology and therapeutic strategies

2022 339 citations Guojun Bu, Chia‐Chen Liu et al. Molecular Neurodegeneration profile →
Performance of plasma phosphorylated tau 181 and 217 in the community

2022 246 citations Guojun Bu, Ronald C. Petersen et al. profile →
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias

2022 166 citations Yuka A. Martens, Na Zhao et al. Neuron profile →
TDP-43 Pathology in Alzheimer’s Disease

2021 166 citations Shunsuke Koga, Dennis W. Dickson et al. Molecular Neurodegeneration profile →
Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes

2021 146 citations Guojun Bu, Ronald C. Petersen et al. profile →
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease

2023 134 citations Yasuteru Inoue, Francis Shue et al. Molecular Neurodegeneration profile →

Peers

Countries citing papers authored by Guojun Bu

Since Specialization

Citations

This map shows the geographic impact of Guojun Bu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Guojun Bu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Guojun Bu more than expected).

Fields of papers citing papers by Guojun Bu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Guojun Bu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Guojun Bu. The network helps show where Guojun Bu may publish in the future.

Co-authorship network of co-authors of Guojun Bu

This figure shows the co-authorship network connecting the top 25 collaborators of Guojun Bu. A scholar is included among the top collaborators of Guojun Bu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Guojun Bu. Guojun Bu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Impact of APOE on cerebrovascular lipid profile in Alzheimer’s disease 2025 ·Acta Neuropathologica ·Yasuteru Inoue, Hu Wang, Michael G. Heckman, Yingxue Ren, Launia J. White, Wenyan Lü, (unknown), Julia TCW, Shunsuke Koga, (unknown), Michael DeTure, (unknown), Ronald C. Petersen, Dennis W. Dickson, Guojun Bu, Xianlin Han, Takahisa Kanekiyo	0
2	Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies 2025 ·Molecular Neurodegeneration ·(unknown), Melissa C. Wren, Feilin Liu, Naomi Kouri, (unknown), Bilal Khalil, (unknown), Michelle Salemi, Brett S. Phinney, Guojun Bu, Na Zhao, Dennis W. Dickson, Melissa E. Murray, Wilfried Rossoll	4
3	The UFMylation pathway is impaired in Alzheimer’s disease 2024 ·Molecular Neurodegeneration ·Tingxiang Yan, Michael G. Heckman, (unknown), Chia‐Chen Liu, (unknown), Xue Wang, Melissa E. Murray, Dennis W. Dickson, Nilüfer Ertekin‐Taner, Zhenkun Lou, Guojun Bu, Wolfdieter Springer, Fabienne C. Fiesel	5
4	Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy 2024 ·Neuron ·Jean Paul Chadarevian, Jonathan Hasselmann, (unknown), (unknown), (unknown), (unknown), (unknown), Christina Tu, Jasmine Nguyen, Sepideh Kiani Shabestari, (unknown), Sunil Gandhi, Guojun Bu, David Hume, Clare Pridans, Zbigniew K. Wszołek, Robert C. Spitale, Hayk Davtyan, Mathew Blurton‐Jones	31
5	Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases 2022 ·Clinical and Translational Medicine ·Rawan Al‐kharboosh, (unknown), (unknown), Guojun Bu, Alfredo Quiñones‐Hinojosa	10
6	Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment 2022 ·Neurology ·Zonghua Li, Michael G. Heckman, Takahisa Kanekiyo, Yuka A. Martens, Gregory S. Day, Maria Vassilaki, Chia‐Chen Liu, David A. Bennett, Ronald C. Petersen, Na Zhao, Guojun Bu	10
7	Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome 2020 ·Stem Cells Translational Medicine ·Wenchun Qu, Zhen Wang, Joshua M. Hare, Guojun Bu, Jorge M. Mallea, Jorge M. Pascual, Arnold I. Caplan, Joanne Kurtzberg, Abba C. Zubair, Eva Kubrova, (unknown), Tarek Nayfeh, Vishal P. Shah, (unknown), Michael E. Wolf, Larry J. Prokop, M. Hassan Murad, Fred Sanfilippo	75
8	Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples 2020 ·Autophagy ·Jens O. Watzlawik, Xu Hou, Dominika Fričová, (unknown), Sandeep Kumar Barodia, Tania F. Gendron, Michael G. Heckman, Michael DeTure, Joanna Siuda, Zbigniew K. Wszołek, Clemens R. Scherzer, Owen A. Ross, Guojun Bu, Dennis W. Dickson, Matthew S. Goldberg, Fabienne C. Fiesel, Wolfdieter Springer	35
9	Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function 2020 ·Neuron ·Yu Yamazaki, Chia‐Chen Liu, Akari Yamazaki, Francis Shue, Yuka A. Martens, Yuanxin Chen, Wenhui Qiao, Aishe Kurti, Hiroshi Oue, Yingxue Ren, Ying Li, Tomonori Aikawa, Yesesri Cherukuri, John Denis Fryer, Yan W. Asmann, Betty Y.S. Kim, Takahisa Kanekiyo, Guojun Bu	45
10	Modeling Neurodegenerative Microenvironment Using Cortical Organoids Derived from Human Stem Cells 2018 ·Tissue Engineering Part A ·Yuanwei Yan, Liqing Song, Julie Bejoy, Jing Zhao, Takahisa Kanekiyo, Guojun Bu, Yi Zhou, (unknown)	65
11	Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway 2015 ·Journal of Biological Chemistry ·(unknown), Yuka Atagi, Yu Yamazaki, Mitsuru Shinohara, Masaya Tachibana, Yuan Fu, Guojun Bu, Takahisa Kanekiyo	52
12	Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy breakdown → 2013 ·Nature Reviews Neurology ·Chia‐Chen Liu, Takahisa Kanekiyo, Huaxi Xu, Guojun Bu	2379
13	A Sorting Nexin 17‐Binding Domain Within the LRP1 Cytoplasmic Tail Mediates Receptor Recycling Through the Basolateral Sorting Endosome 2013 ·Traffic ·Pamela Farfán, Jiyeon Lee, Jorge Larios, Pablo H. Sotelo, Guojun Bu, María‐Paz Marzolo	39
14	APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease 2012 ·Journal of Biological Chemistry ·Katherine L. Youmans, Leon M. Tai, Evelyn Nwabuisi‐Heath, Lisa M. Jungbauer, Takahisa Kanekiyo, Ming Gan, Jungsu Kim, William A. Eimer, Steve Estus, G. William Rebeck, Edwin J. Weeber, Guojun Bu, Chunjiang Yu, Mary Jo LaDu	214
15	LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid-β 2012 ·Journal of Neuroscience ·Takahisa Kanekiyo, Chia‐Chen Liu, Mitsuru Shinohara, Jie Li, Guojun Bu	180
16	Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid-β Uptake 2011 ·Journal of Neuroscience ·Takahisa Kanekiyo, Juan Zhang, Qiang Liu, Chia‐Chen Liu, Lijuan Zhang, Guojun Bu	178
17	Low-Density Lipoprotein Receptor-Related Protein 1 Promotes Cancer Cell Migration and Invasion by Inducing the Expression of Matrix Metalloproteinases 2 and 9 2009 ·Cancer Research ·Heesang Song, Yonghe Li, Jiyeon Lee, Alan L. Schwartz, Guojun Bu	159
18	LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein 2008 ·Journal of Cell Science ·(unknown), (unknown), Roy C. Mootoosamy, Claire Sunyach, Christian Jacobsen, Claus Oxvig, Søren K. Moestrup, Qiang Liu, Guojun Bu, Angela Jen, Roger J. Morris	91
19	Morphological, cytological and molecular characterization of a novel symmetric somatic hybrid between N. tabacum and N. glauca 2007 ·Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology ·Yuqiang Sun, Qi Xue, (unknown), (unknown), (unknown), Ming Gong, Guojun Bu, (unknown)	1
20	Nuclear Targeting by the Growth Factor Midkine 2002 ·Molecular and Cellular Biology ·Yoshihisa Shibata, Takashi Muramatsu, Makoto Hirai, Tatsuya Inui, Terutoshi Kimura, Hidehiko Saito, Lynn M. McCormick, Guojun Bu, Kenji Kadomatsu	117

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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