Sangram S. Sisodia

42.0k total citations · 18 hit papers
240 papers, 33.5k citations indexed

About

Sangram S. Sisodia is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Sangram S. Sisodia has authored 240 papers receiving a total of 33.5k indexed citations (citations by other indexed papers that have themselves been cited), including 165 papers in Physiology, 132 papers in Molecular Biology and 55 papers in Cellular and Molecular Neuroscience. Recurrent topics in Sangram S. Sisodia's work include Alzheimer's disease research and treatments (162 papers), Prion Diseases and Protein Misfolding (44 papers) and Cholinesterase and Neurodegenerative Diseases (27 papers). Sangram S. Sisodia is often cited by papers focused on Alzheimer's disease research and treatments (162 papers), Prion Diseases and Protein Misfolding (44 papers) and Cholinesterase and Neurodegenerative Diseases (27 papers). Sangram S. Sisodia collaborates with scholars based in United States, Germany and Canada. Sangram S. Sisodia's co-authors include Donald L. Price, David Borchelt, Gopal Thinakaran, Michael K. Lee, Hilda H. Slunt, Don W. Cleveland, Neal G. Copeland, Philip C. Wong, Edward H. Koo and Sam Gandy and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Sangram S. Sisodia

239 papers receiving 32.9k citations

Hit Papers

APP Processing and Synaptic Function 1990 2026 2002 2014 2003 1996 1995 1997 2006 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. APP Processing and Synaptic Function
    2003 1.3k citations Taisuke Tomita, David Borchelt et al. Neuron profile →
  2. Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo
    1996 1.2k citations David Borchelt, Gopal Thinakaran et al. Neuron profile →
  3. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    1995 1.2k citations David Borchelt, Michael K. Lee et al. Neuron profile →
  4. ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions
    1997 1.1k citations Michael K. Lee, Neal G. Copeland et al. Neuron profile →
  5. AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss
    2006 865 citations Takeshi Iwatsubo, Taisuke Tomita et al. Neuron profile →
  6. Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo
    1996 863 citations Gopal Thinakaran, David Borchelt et al. Neuron profile →
  7. Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins
    1997 830 citations David Borchelt, Tamara Ratovitski et al. Neuron profile →
  8. Trafficking and Proteolytic Processing of APP
    2012 809 citations Gopal Thinakaran, Sangram S. Sisodia et al. profile →
  9. Evidence that β-Amyloid Protein in Alzheimer's Disease Is Not Derived by Normal Processing
    1990 754 citations Sangram S. Sisodia, Donald L. Price et al. profile →
  10. A mouse model for Down syndrome exhibits learning and behaviour deficits
    1995 724 citations Sangram S. Sisodia et al. profile →
  11. Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice
    2005 701 citations Sangram S. Sisodia et al. profile →
  12. Beta-amyloid precursor protein cleavage by a membrane-bound protease.
    1992 593 citations Sangram S. Sisodia profile →
  13. Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm
    1997 591 citations Donald L. Price, Sangram S. Sisodia et al. profile →
  14. Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
    1990 591 citations Sangram S. Sisodia, Lee J. Martin et al. profile →
  15. β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
    1995 566 citations Sangram S. Sisodia et al. profile →
  16. Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
    2011 540 citations Sangram S. Sisodia et al. profile →
  17. Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease
    2016 502 citations Myles R. Minter, Can Zhang et al. Scientific Reports profile →
  18. The gut microbiome in Alzheimer’s disease: what we know and what remains to be explored
    2023 174 citations Sidhanth Chandra, Sangram S. Sisodia et al. Molecular Neurodegeneration profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Sangram S. Sisodia United States 91 20.9k 15.8k 8.4k 5.5k 4.7k 240 33.5k
Takaomi C. Saido Japan 98 19.6k 0.9× 16.3k 1.0× 8.2k 1.0× 4.5k 0.8× 6.0k 1.3× 504 36.1k
Bart De Strooper Belgium 122 28.1k 1.3× 26.7k 1.7× 9.2k 1.1× 7.6k 1.4× 6.0k 1.3× 392 51.6k
Todd E. Golde United States 94 18.8k 0.9× 14.2k 0.9× 5.7k 0.7× 5.3k 1.0× 2.4k 0.5× 314 32.1k
Ralph A. Nixon United States 102 17.6k 0.8× 14.5k 0.9× 7.3k 0.9× 3.8k 0.7× 11.3k 2.4× 323 37.8k
Jesús Ávila Spain 95 13.9k 0.7× 16.1k 1.0× 10.1k 1.2× 3.7k 0.7× 6.3k 1.3× 650 33.7k
Christian Haass Germany 112 29.7k 1.4× 24.0k 1.5× 9.7k 1.2× 7.6k 1.4× 7.0k 1.5× 384 49.9k
Donald L. Price United States 108 17.3k 0.8× 16.9k 1.1× 16.3k 1.9× 7.2k 1.3× 4.2k 0.9× 365 44.1k
Peter St George‐Hyslop Canada 83 16.8k 0.8× 12.1k 0.8× 5.3k 0.6× 3.7k 0.7× 3.1k 0.7× 391 28.3k
Bruce A. Yankner United States 57 12.1k 0.6× 13.5k 0.9× 5.6k 0.7× 3.2k 0.6× 3.6k 0.8× 79 26.4k
Edward H. Koo United States 75 17.2k 0.8× 11.6k 0.7× 5.1k 0.6× 4.8k 0.9× 3.7k 0.8× 187 23.7k

Countries citing papers authored by Sangram S. Sisodia

Since Specialization
Citations

This map shows the geographic impact of Sangram S. Sisodia's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sangram S. Sisodia with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sangram S. Sisodia more than expected).

Fields of papers citing papers by Sangram S. Sisodia

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sangram S. Sisodia. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sangram S. Sisodia. The network helps show where Sangram S. Sisodia may publish in the future.

Co-authorship network of co-authors of Sangram S. Sisodia

This figure shows the co-authorship network connecting the top 25 collaborators of Sangram S. Sisodia. A scholar is included among the top collaborators of Sangram S. Sisodia based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sangram S. Sisodia. Sangram S. Sisodia is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chandra, Sidhanth, Naveen Kumar Singhal, Elyse Watkins, et al.. (2025). The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17. Journal of Clinical Investigation. 135(13). 2 indexed citations
2.
Saha, Piyali & Sangram S. Sisodia. (2024). Role of the gut microbiome in mediating sex-specific differences in the pathophysiology of Alzheimer's disease. Neurotherapeutics. 21(6). e00426–e00426. 6 indexed citations
3.
Chandra, Sidhanth, Antonio Di Meco, Hemraj B. Dodiya, et al.. (2023). The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms. Molecular Neurodegeneration. 18(1). 45–45. 40 indexed citations
4.
Chandra, Sidhanth, Sangram S. Sisodia, & Robert Vassar. (2023). The gut microbiome in Alzheimer’s disease: what we know and what remains to be explored. Molecular Neurodegeneration. 18(1). 9–9. 174 indexed citations breakdown →
5.
Dodiya, Hemraj B., Holly L. Lutz, Priyam Patel, et al.. (2021). Gut microbiota–driven brain Aβ amyloidosis in mice requires microglia. The Journal of Experimental Medicine. 219(1). 77 indexed citations
6.
Minter, Myles R., Reinhard Hinterleitner, Marlies Meisel, et al.. (2017). Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer’s disease. Scientific Reports. 7(1). 10411–10411. 229 indexed citations
7.
Butkinaree, Chutikarn, Maryssa Canuel, Rachid Essalmani, et al.. (2015). Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. Journal of Biological Chemistry. 290(30). 18609–18620. 42 indexed citations
8.
Louvi, Angeliki, Sangram S. Sisodia, & Elizabeth A. Grove. (2004). Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 131(13). 3093–3105. 34 indexed citations
9.
Iqbal, Khalid, Sangram S. Sisodia, Bengt Winblad, & Related Disorders. (2001). Alzheimer's disease : advances in etiology, pathogenesis, and therapeutics. Wiley eBooks. 63 indexed citations
10.
Sisodia, Sangram S., et al.. (2001). Alzheimer's Disease: Clinical, Biological, and Therapeutic Perspectives. Journal of Molecular Neuroscience. 17(2). 99–99. 2 indexed citations
11.
Kim, Seong‐Hun, Bridget E. Berechid, Sarah Bingham, et al.. (2000). Requirement for Presenilin 1 in Facilitating Jagged 2-Mediated Endoproteolysis and Signaling of Notch 1. Journal of Molecular Neuroscience. 15(3). 189–204. 43 indexed citations
12.
Takahashi, Masaaki, Sylvain Doré, Christopher D. Ferris, et al.. (2000). Amyloid Precursor Proteins Inhibit Heme Oxygenase Activity and Augment Neurotoxicity in Alzheimer's Disease. Neuron. 28(2). 461–473. 150 indexed citations
13.
Herms, Jochen, Johannes A. Hainfellner, Adriano Aguzzi, et al.. (2000). Mice with Combined Gene Knock-Outs Reveal Essential and Partially Redundant Functions of Amyloid Precursor Protein Family Members. Journal of Neuroscience. 20(21). 7951–7963. 395 indexed citations
14.
Berechid, Bridget E., Gopal Thinakaran, Pauline Wong, Sangram S. Sisodia, & Jeffrey S. Nye. (1999). Lack of requirement for Presenilin1 in Notch1 signaling. Current Biology. 9(24). 1493–1497. 36 indexed citations
15.
Lyckman, Alvin W., Annamaria Confaloni, Gopal Thinakaran, Sangram S. Sisodia, & Kenneth L. Moya. (1998). Post-translational Processing and Turnover Kinetics of Presynaptically Targeted Amyloid Precursor Superfamily Proteins in the Central Nervous System. Journal of Biological Chemistry. 273(18). 11100–11106. 66 indexed citations
16.
Borchelt, David, Tamara Ratovitski, Michael K. Lee, et al.. (1997). Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins. Neuron. 19(4). 939–945. 830 indexed citations breakdown →
17.
Bergin, Ann M., Grace Kim, Donald L. Price, et al.. (1997). Identification and characterization of a mouse homologue of the Spinal Muscular Atrophy-determining gene, survival motor neuron. Gene. 204(1-2). 47–53. 35 indexed citations
18.
Thinakaran, Gopal, David B. Teplow, Robert Siman, Barry Greenberg, & Sangram S. Sisodia. (1996). Metabolism of the “Swedish” Amyloid Precursor Protein Variant in Neuro2a (N2a) Cells. Journal of Biological Chemistry. 271(16). 9390–9397. 275 indexed citations
19.
Sisodia, Sangram S., Lee J. Martin, Lary C. Walker, David Borchelt, & Donald L. Price. (1995). CELLULAR AND MOLECULAR BIOLOGY OF ALZHEIMER'S DISEASE AND ANIMAL MODELS. Neuroimaging Clinics of North America. 5(1). 59–68. 6 indexed citations
20.
Sisodia, Sangram S., Barbara Sollner-Webb, & Don W. Cleveland. (1987). Specificity of RNA Maturation Pathways: RNAs Transcribed by RNA Polymerase III Are Not Substrates for Splicing or Polyadenylation. Molecular and Cellular Biology. 7(10). 3602–3612. 42 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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