Dorit Trudler

2.5k total citations · 1 hit paper
24 papers, 1.8k citations indexed

About

Dorit Trudler is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Neurology. According to data from OpenAlex, Dorit Trudler has authored 24 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Molecular Biology, 9 papers in Cellular and Molecular Neuroscience and 9 papers in Neurology. Recurrent topics in Dorit Trudler's work include Alzheimer's disease research and treatments (8 papers), Neuroinflammation and Neurodegeneration Mechanisms (8 papers) and Parkinson's Disease Mechanisms and Treatments (6 papers). Dorit Trudler is often cited by papers focused on Alzheimer's disease research and treatments (8 papers), Neuroinflammation and Neurodegeneration Mechanisms (8 papers) and Parkinson's Disease Mechanisms and Treatments (6 papers). Dorit Trudler collaborates with scholars based in United States, Israel and Japan. Dorit Trudler's co-authors include Dan Frenkel, Stuart A. Lipton, Dorit Farfara, Ehud Gazit, Lilach Vaks, Andrea Magno, Amedeo Caflisch, Lihi Adler‐Abramovich, Dan Frenkel and Swagata Ghatak and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Neuroscience and Immunity.

In The Last Decade

Dorit Trudler

24 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

2021 281 citations Hongxu Xian, Yuan Liu et al. Immunity profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dorit Trudler United States	18	809	472	424	367	305	24	1.8k
Jia Lu Singapore	32	1.5k 1.8×	355 0.8×	953 2.2×	278 0.8×	216 0.7×	65	3.5k
Young‐Sook Kang South Korea	29	1.3k 1.6×	340 0.7×	262 0.6×	449 1.2×	157 0.5×	81	2.8k
Szilvia Veszelka Hungary	30	687 0.8×	284 0.6×	835 2.0×	261 0.7×	119 0.4×	57	2.5k
Siti R. Yusof Malaysia	13	1.3k 1.6×	492 1.0×	1.7k 4.0×	446 1.2×	345 1.1×	26	4.2k
Christoph Kuhlmann Germany	25	640 0.8×	338 0.7×	445 1.0×	192 0.5×	164 0.5×	41	1.9k
Dario Domenico Lofrumento Italy	27	600 0.7×	591 1.3×	402 0.9×	259 0.7×	236 0.8×	70	2.1k
Marco Feligioni Italy	31	1.1k 1.4×	530 1.1×	391 0.9×	663 1.8×	203 0.7×	65	2.3k
Patrick T. Ronaldson United States	30	979 1.2×	433 0.9×	1.4k 3.4×	307 0.8×	254 0.8×	57	3.4k
Leah P. Shriver United States	28	946 1.2×	270 0.6×	588 1.4×	293 0.8×	120 0.4×	75	3.1k
Werner J. Geldenhuys United States	30	1.2k 1.4×	288 0.6×	218 0.5×	363 1.0×	301 1.0×	124	2.7k

Countries citing papers authored by Dorit Trudler

Since Specialization

Citations

This map shows the geographic impact of Dorit Trudler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dorit Trudler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dorit Trudler more than expected).

Fields of papers citing papers by Dorit Trudler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dorit Trudler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dorit Trudler. The network helps show where Dorit Trudler may publish in the future.

Co-authorship network of co-authors of Dorit Trudler

This figure shows the co-authorship network connecting the top 25 collaborators of Dorit Trudler. A scholar is included among the top collaborators of Dorit Trudler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dorit Trudler. Dorit Trudler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Farfara, Dorit, Limor Avrahami, Dorit Trudler, et al.. (2023). Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice. Journal of Neuroinflammation. 20(1). 174–174. 7 indexed citations

Yang, Hongmei, Chang-ki Oh, Haitham Amal, et al.. (2022). Mechanistic insight into female predominance in Alzheimer’s disease based on aberrant protein S-nitrosylation of C3. Science Advances. 8(50). eade0764–eade0764. 43 indexed citations

Trudler, Dorit, Kristopher L. Nazor, Yvonne S. Eisele, et al.. (2021). Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia. Proceedings of the National Academy of Sciences. 118(15). 98 indexed citations

Trudler, Dorit, Sara Sanz‐Blasco, Yvonne S. Eisele, et al.. (2021). α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss. Journal of Neuroscience. 41(10). 2264–2273. 80 indexed citations

Xian, Hongxu, Yuan Liu, A. Nilsson, et al.. (2021). Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. Immunity. 54(7). 1463–1477.e11. 281 indexed citations breakdown →

Xian, Hongxu, A. Nilsson, Timothy R. Crother, et al.. (2020). Short Term Metformin Intervention Inhibits IL-6 and IL-1β Secretion and Prevents Acute Respiratory Distress Syndrome-Implications for COVID-19. SSRN Electronic Journal. 1 indexed citations

Ghatak, Swagata, Nima Dolatabadi, Richard Gao, et al.. (2020). NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models. Molecular Psychiatry. 26(10). 5751–5765. 58 indexed citations

Trudler, Dorit, et al.. (2019). Alpha synuclein deficiency increases CD4 ⁺ T‐cells pro‐inflammatory profile in a Nurr1‐dependent manner. Journal of Neurochemistry. 152(1). 61–71. 5 indexed citations

Ghatak, Swagata, Nima Dolatabadi, Dorit Trudler, et al.. (2019). Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls. eLife. 8. 158 indexed citations

10.

Nagar, Saumya, Dorit Trudler, Scott R. McKercher, et al.. (2017). Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency. Investigative Ophthalmology & Visual Science. 58(9). 3741–3741. 6 indexed citations

11.

Schmukler, Eran, et al.. (2017). DJ‐1 deficiency impairs autophagy and reduces alpha‐synuclein phagocytosis by microglia. Journal of Neurochemistry. 143(5). 584–594. 92 indexed citations

12.

Nagar, Saumya, Dorit Trudler, Kevin Lopez, et al.. (2017). MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress. Proceedings of the National Academy of Sciences. 114(20). E4048–E4056. 30 indexed citations

13.

Iram, Tal, Dorit Trudler, David Kain, et al.. (2016). Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection. Neurobiology of Disease. 96. 84–94. 91 indexed citations

14.

Trudler, Dorit, et al.. (2015). New insights on Parkinson’s disease genes: the link between mitochondria impairment and neuroinflammation. Journal of Neural Transmission. 122(10). 1409–1419. 25 indexed citations

15.

Farfara, Dorit, Hana Tuby, Dorit Trudler, et al.. (2014). Low-Level Laser Therapy Ameliorates Disease Progression in a Mouse Model of Alzheimer’s Disease. Journal of Molecular Neuroscience. 55(2). 430–436. 85 indexed citations

16.

Trudler, Dorit, Orly Weinreb, Silvia Mandel, Moussa B. H. Youdim, & Dan Frenkel. (2013). DJ‐1 deficiency triggers microglia sensitivity to dopamine toward a pro‐inflammatory phenotype that is attenuated by rasagiline. Journal of Neurochemistry. 129(3). 434–447. 81 indexed citations

17.

Trudler, Dorit, et al.. (2013). Preconditioning to mild oxidative stress mediates astroglial neuroprotection in an IL-10-dependent manner. Brain Behavior and Immunity. 30. 176–185. 33 indexed citations

18.

Adler‐Abramovich, Lihi, Lilach Vaks, Dorit Trudler, et al.. (2012). Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria. Nature Chemical Biology. 8(8). 701–706. 378 indexed citations

19.

Scherzer‐Attali, Roni, Dorit Farfara, Itzik Cooper, et al.. (2012). Naphthoquinone-tyrptophan reduces neurotoxic Aβ*56 levels and improves cognition in Alzheimer's disease animal model. Neurobiology of Disease. 46(3). 663–672. 33 indexed citations

20.

Farfara, Dorit, et al.. (2010). γ‐Secretase component presenilin is important for microglia β‐amyloid clearance. Annals of Neurology. 69(1). 170–180. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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