Stuart L. Schreiber

132.6k total citations · 34 hit papers
600 papers, 91.9k citations indexed

About

Stuart L. Schreiber is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Stuart L. Schreiber has authored 600 papers receiving a total of 91.9k indexed citations (citations by other indexed papers that have themselves been cited), including 443 papers in Molecular Biology, 199 papers in Organic Chemistry and 75 papers in Oncology. Recurrent topics in Stuart L. Schreiber's work include Chemical Synthesis and Analysis (106 papers), Signaling Pathways in Disease (84 papers) and Synthetic Organic Chemistry Methods (64 papers). Stuart L. Schreiber is often cited by papers focused on Chemical Synthesis and Analysis (106 papers), Signaling Pathways in Disease (84 papers) and Synthetic Organic Chemistry Methods (64 papers). Stuart L. Schreiber collaborates with scholars based in United States, United Kingdom and Germany. Stuart L. Schreiber's co-authors include Christian A. Hassig, Gavin MacBeath, Christina M. Grozinger, B Bernstein, Robert H. Crabtree, Martin D. Burke, Alykhan F. Shamji, Jon Clardy, Robert F. Standaert and Jun S. Liu and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Stuart L. Schreiber

591 papers receiving 89.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Regulation of Ferroptotic Cancer Cell Death by GPX4

2014 5.5k citations Paul A. Clemons, Alykhan F. Shamji et al. profile →
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

2006 4.0k citations Stuart L. Schreiber et al. profile →
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 3.5k citations Stuart L. Schreiber et al. profile →
Printing Proteins as Microarrays for High-Throughput Function Determination

2000 2.3k citations Stuart L. Schreiber et al. Science profile →
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

2008 2.2k citations Stuart L. Schreiber et al. profile →
Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery

2000 2.2k citations Stuart L. Schreiber Science profile →
The mechanism of action of cyclosporin A and FK506

1992 1.8k citations Stuart L. Schreiber et al. profile →
Active genes are tri-methylated at K4 of histone H3

2002 1.7k citations Stuart L. Schreiber et al. profile →
A mammalian protein targeted by G1-arresting rapamycin–receptor complex

1994 1.6k citations Stuart L. Schreiber et al. profile →
A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 1.5k citations Stuart L. Schreiber et al. Science profile →
Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

1999 1.5k citations Stephen J. Haggarty, Stuart L. Schreiber et al. Science profile →
Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 1.4k citations Stuart L. Schreiber et al. Science profile →
A Planning Strategy for Diversity‐Oriented Synthesis

2003 1.3k citations Stuart L. Schreiber et al. Angewandte Chemie International Edition profile →
Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells

2013 1.3k citations Jan Krönke, Namrata D. Udeshi et al. Science profile →
Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 1.3k citations Stuart L. Schreiber Science profile →
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

2017 1.2k citations Stuart L. Schreiber et al. profile →
Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

2005 1.2k citations Stuart L. Schreiber et al. profile →
Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin

1993 1.1k citations Stuart L. Schreiber et al. profile →
Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

1997 1.1k citations Stuart L. Schreiber et al. profile →
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

2003 861 citations Stephen J. Haggarty, Stuart L. Schreiber et al. Proceedings of the National Academy of Sciences profile →
Structure of the FKBP12-Rapamycin Complex Interacting with Binding Domain of Human FRAP

1996 727 citations Stuart L. Schreiber et al. Science profile →
Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions

1994 715 citations Sibo Feng, Stuart L. Schreiber et al. Science profile →
Controlling Signal Transduction with Synthetic Ligands

1993 708 citations Stuart L. Schreiber et al. Science profile →
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

2019 663 citations Vlado Dančík, Bridget K. Wagner et al. profile →
Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

1997 656 citations Stuart L. Schreiber et al. profile →
Three proteins define a class of human histone deacetylases related to yeast Hda1p

1999 654 citations Stuart L. Schreiber et al. Proceedings of the National Academy of Sciences profile →
Control of p70 S6 kinase by kinase activity of FRAP in vivo

1995 615 citations Stuart L. Schreiber et al. profile →
Methylation of histone H3 Lys 4 in coding regions of active genes

2002 595 citations Stuart L. Schreiber et al. Proceedings of the National Academy of Sciences profile →
Cytochrome P450 oxidoreductase contributes tophospholipid peroxidation in ferroptosis

2020 565 citations Stuart L. Schreiber et al. profile →
Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

1998 561 citations Stuart L. Schreiber et al. profile →
Atomic Structure of FKBP-FK506, an Immunophilin-Immunosuppressant Complex

1991 552 citations Stuart L. Schreiber et al. Science profile →
Histone Variant H2A.Z Marks the 5′ Ends of Both Active and Inactive Genes in Euchromatin

2005 532 citations Stuart L. Schreiber et al. profile →
Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3- 3-dependent cellular localization

2000 507 citations Stuart L. Schreiber et al. Proceedings of the National Academy of Sciences profile →
The Rise of Molecular Glues

2021 371 citations Stuart L. Schreiber profile →

Peers

Countries citing papers authored by Stuart L. Schreiber

Since Specialization

Citations

This map shows the geographic impact of Stuart L. Schreiber's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stuart L. Schreiber with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stuart L. Schreiber more than expected).

Fields of papers citing papers by Stuart L. Schreiber

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stuart L. Schreiber. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stuart L. Schreiber. The network helps show where Stuart L. Schreiber may publish in the future.

Co-authorship network of co-authors of Stuart L. Schreiber

This figure shows the co-authorship network connecting the top 25 collaborators of Stuart L. Schreiber. A scholar is included among the top collaborators of Stuart L. Schreiber based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stuart L. Schreiber. Stuart L. Schreiber is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders 2024 ·Journal of the American Chemical Society ·Zhonglin Liu, Jarrett R. Remsberg, (unknown), Evert Njomen, Kristen E. DeMeester, Yongfeng Tao, Guoqin Xia, (unknown), (unknown), (unknown), Gabriel M. Simon, Stuart L. Schreiber, Bruno Melillo, Benjamin F. Cravatt	19
2	Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2 2023 ·Angewandte Chemie International Edition ·Yongfeng Tao, (unknown), Zhongyu Zou, Evert Njomen, Jarrett R. Remsberg, Daisuke Ogasawara, Chang Ye, Bruno Melillo, Stuart L. Schreiber, Chuan He, David Remillard, Benjamin F. Cravatt	40
3	Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity 2021 ·Cell Reports Medicine ·(unknown), Alessandra Dall’Agnese, (unknown), (unknown), Julien Dubrulle, Hannah L. Johnson, Fabio Stossi, Patricia C. Cogswell, Josh Sommer, Joan Levy, Tanaz Sharifnia, Mathias J. Wawer, Behnam Nabet, Nathanael S. Gray, Paul A. Clemons, Stuart L. Schreiber, Paul Workman, Richard A. Young, Charles Y. Lin	20
4	Modular, stereocontrolled C _β –H/C _α –C activation of alkyl carboxylic acids 2019 ·Proceedings of the National Academy of Sciences ·Ming Shang, Karla Santos Feu, Julien C. Vantourout, Lisa M. Barton, Heather L. Osswald, Nobutaka Kato, Kerstin Gagaring, Case W. McNamara, Gang Chen, Liang Hu, Shengyang Ni, (unknown), Miao Chen, Rohan R. Merchant, Tian Qin, Stuart L. Schreiber, Bruno Melillo, Jin‐Quan Yu, Phil S. Baran	42
5	Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development 2019 ·Proceedings of the National Academy of Sciences ·Sonia M. Vallabh, Chloe K. Nobuhara, Franc Llorens, Inga Zerr, Piero Parchi, Sabina Capellari, Eric Kuhn, Jacob A. Klickstein, Jiri Safar, Flávia C. Nery, Kathryn J. Swoboda, Michael D. Geschwind, Henrik Zetterberg, Steven E. Arnold, Eric Vallabh Minikel, Stuart L. Schreiber	27
6	Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds 2018 ·Journal of the American Chemical Society ·Bruno Melillo, Jochen Zoller, Bruce K. Hua, Oscar Verho, Jannik C. Borghs, (unknown), Micah Maetani, Mathias J. Wawer, Paul A. Clemons, Stuart L. Schreiber	49
7	KRAS Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine 2015 ·Cancer Research ·Michelle L. Stewart, Pablo Tamayo, Andrew J. Wilson, Stephanie Wang, Daniel Y. Chang, Jong W. Kim, Dineo Khabele, Alykhan F. Shamji, Stuart L. Schreiber	31
8	Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation 2015 ·eLife ·Zhengjian Zhang, Žarko Bošković, Mahmud M. Hussain, Wenxin Hu, Carla Inouye, Han‐Je Kim, (unknown), Mary Kathryn Doud, Timothy A. Lewis, Angela N. Koehler, Stuart L. Schreiber, Robert Tjian	39
9	Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase Inhibitors by Multimodality Molecular Imaging in Living Subjects 2014 ·Cancer Research ·Carmel T. Chan, Jun Qi, William Smith, (unknown), Ralph Mazitschek, Nathan West, Robert E. Reeves, Gabriela Chiosis, Stuart L. Schreiber, James E. Bradner, Ramasamy Paulmurugan, Sanjiv S. Gambhir	12
10	Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer 2013 ·Cancer Research ·Mohamed E. Abazeed, Drew Adams, Kristen E. Hurov, Pablo Tamayo, Chad J. Creighton, Dmitriy Sonkin, Andrew O. Giacomelli, (unknown), (unknown), Kwok‐Kin Wong, Jill P. Mesirov, Jay S. Loeffler, Stuart L. Schreiber, Peter S. Hammerman, Matthew Meyerson	90
11	Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells breakdown → 2013 ·Science ·Jan Krönke, Namrata D. Udeshi, Anupama Narla, Peter Grauman, Slater N. Hurst, Marie McConkey, Tanya Svinkina, Dirk Heckl, Eamon Comer, Xiaoyu Li, Christie Ciarlo, Emily C. Hartman, Nikhil C. Munshi, Monica Schenone, Stuart L. Schreiber, Steven A. Carr, Benjamin L. Ebert	1288
12	The identification and characterization of non-reactive inhibitor of Keap1-Nrf2 interaction through HTS using a fluorescence polarization assay 2013 ·Europe PMC (PubMed Central) ·Lili Wang, Timothy A. Lewis, Yanling Zhang, Carol Khodier, Sadagopan Magesh, Lin Chen, Daigo Inoyama, Yu Chen, Jing Zhen, Longqin Hu, Lesa J. Beamer, Patrick W. Faloon, Sivaraman Dandapani, José R. Perez, Benito Muñoz, Michelle Palmer, Stuart L. Schreiber	7
13	Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles 2010 ·Proceedings of the National Academy of Sciences ·Paul A. Clemons, Nicole E. Bodycombe, (unknown), Joshua Wilson, Alykhan F. Shamji, Bridget K. Wagner, Angela N. Koehler, Stuart L. Schreiber	280
14	Small-molecule inducers of insulin expression in pancreatic α-cells 2010 ·Proceedings of the National Academy of Sciences ·Dina Fomina‐Yadlin, Stefan Kubicek, Deepika Walpita, Vlado Dančík, Jacob Hecksher‐Sørensen, Joshua A. Bittker, Tanaz Sharifnia, Alykhan F. Shamji, Paul A. Clemons, Bridget K. Wagner, Stuart L. Schreiber	58
15	Identifying the proteins to which small-molecule probes and drugs bind in cells 2009 ·Proceedings of the National Academy of Sciences ·Shao‐En Ong, Monica Schenone, Adam A. Margolin, Xiaoyu Li, (unknown), Mary Kathryn Doud, D.R. Mani, Letian Kuai, Xiang Wang, John L. Wood, Nicola Tolliday, Angela N. Koehler, Lisa A. Marcaurelle, Todd R. Golub, Robert J. Gould, Stuart L. Schreiber, Steven A. Carr	237
16	Perturbational profiling of nanomaterial biologic activity 2008 ·Proceedings of the National Academy of Sciences ·Stanley Y. Shaw, (unknown), Mikäel J. Pittet, Aravind Subramanian, Stuart L. Schreiber, Ralph Weissleder	188
17	SpectralNET – an application for spectral graph analysis and visualization 2005 ·BMC Bioinformatics ·Joshua J Forman, Paul A. Clemons, Stuart L. Schreiber, Stephen J. Haggarty	21
18	Identification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection 2004 ·Proceedings of the National Academy of Sciences ·Rebecca A. Butcher, Stuart L. Schreiber	19
19	SIR1, an Upstream Component in Auxin Signaling Identified by Chemical Genetics 2003 ·Science ·Yunde Zhao, Xinhua Dai, Helen E. Blackwell, Stuart L. Schreiber, Joanne Chory	140
20	Structure-Function Analysis of SH3 Domains: SH3 Binding Specificity Altered by Single Amino Acid Substitutions 1995 ·Molecular and Cellular Biology ·Zhigang Weng, Richard J. Rickles, Sibo Feng, Stéphane Richard, Andréy S. Shaw, Stuart L. Schreiber, Joan S. Brugge	111

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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