Richard J. Rickles

5.1k citations

44 papers · 4.3k indexed · 1 hit paper · h-index 26

Molecular Biology top 2%
Cancer Research top 5%
Genetics top 5%
Oncology top 10%
Immunology top 10%

Co-authors: Sidney Strickland Guang Hu Gregory J. Hannon Stephen J. Elledge Andrew L. Darrow Martyn C. Botfield Joan S. Brugge Frank Stegmeier
Topics: Protease and Inhibitor Mechanisms (8 papers)Protein Kinase Regulation and GTPase Signaling (7 papers)Peptidase Inhibition and Analysis (7 papers)
Cited by: Molecular Biology Immunology and Allergy Cancer Research
Journals: Science Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Switzerland Australia

In The Last Decade

Richard J. Rickles

44 papers receiving 4.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Synergistic drug combinations tend to improve therapeutically relevant selectivity

2009 742 citations Joseph Lehár, Andrew Krueger et al. Nature Biotechnology profile →

Peers

Countries citing papers authored by Richard J. Rickles

Since Specialization

Citations

This map shows the geographic impact of Richard J. Rickles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard J. Rickles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard J. Rickles more than expected).

Fields of papers citing papers by Richard J. Rickles

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard J. Rickles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard J. Rickles. The network helps show where Richard J. Rickles may publish in the future.

Co-authorship network of co-authors of Richard J. Rickles

This figure shows the co-authorship network connecting the top 25 collaborators of Richard J. Rickles. A scholar is included among the top collaborators of Richard J. Rickles based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Richard J. Rickles. Richard J. Rickles is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Identification of Combinatorial Drugs that Synergistically Kill both Eribulin-Sensitive and Eribulin- Insensitive Tumor Cells 2015 ·Richard J. Rickles,Junji Matsui,Ping Zhu,Yasuhiro Funahashi,Jill M. Grenier,(unknown),Nanding Zhao,Bruce A. Littlefield,K. Nomoto,(unknown)	1
2	Adenosine A2A and Beta-2 Adrenergic Receptor Agonists: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening 2012 ·Molecular Cancer Therapeutics ·Richard J. Rickles,Winnie F. Tam,Thomas P. Giordano,Laura Pierce,(unknown),Douglas W. McMillin,(unknown),David Crowe,Mei Chen,William Avery,Vikram Kansra,Steffan T. Nawrocki,Jennifer S. Carew,Francis J. Giles,Constantine S. Mitsiades,Alexis A. Borisy,Kenneth C. Anderson,Margaret Lee	13
3	Synergistic drug combinations tend to improve therapeutically relevant selectivitybreakdown → 2009 ·Nature Biotechnology ·Joseph Lehár,Andrew Krueger,William Avery,Adrian Heilbut,Lisa M. Johansen,Edward Price,Richard J. Rickles,Glenn F. Short,Jane Staunton,Xiaowei Jin,Margaret Lee,Grant R. Zimmermann,Alexis A. Borisy	742
4	A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells 2005 ·Proceedings of the National Academy of Sciences ·Frank Stegmeier,Guang Hu,Richard J. Rickles,Gregory J. Hannon,Stephen J. Elledge	437
5	Second-generation shRNA libraries covering the mouse and human genomes 2005 ·Nature Genetics ·José M. Silva,Mamie Z. Li,Ken C. N. Chang,Wei Ge,Michael C. Golding,Richard J. Rickles,Despina Siolas,Guang Hu,Patrick J. Paddison,Michael R. Schlabach,Nihar U. Sheth,Jeff Bradshaw,(unknown),Amit Kulkarni,Guy Cavet,Ravi Sachidanandam,W. Richard McCombie,Michele A. Cleary,Stephen J. Elledge,Gregory J. Hannon	491
6	A Src SH2 selective binding compound inhibits osteoclast-mediated resorption 2000 ·Chemistry & Biology ·Shelia M. Violette,William C. Shakespeare,Catherine Bartlett,Wei Guan,Jeremy A. Smith,Richard J. Rickles,Regine S. Bohacek,Dennis A. Holt,Roland Baron,Tomi K. Sawyer	47
7	Simultaneous Assay of Src SH3 and SH2 Domain Binding Using Different Wavelength Fluorescence Polarization Probes 1999 ·Analytical Biochemistry ·Berkley A. Lynch,Charles A. Minor,Kara A. Loiacono,Marie Rose van Schravendijk,Mary K. Ram,Raji Sundaramoorthi,Susan Adams,Tom R. Phillips,Dennis A. Holt,Richard J. Rickles,Ian A. MacNeil	16
8	A novel mechanism-based mammalian cell assay for the identification of SH2-domain-specific protein-protein inhibitors 1998 ·Chemistry & Biology ·Richard J. Rickles,(unknown),Wei Guan,Mihai Azimioara,William C. Shakespeare,Shelia M. Violette,Mark J. Zoller	6
9	SH3 domains and drug design: Ligands, structure, and biological function 1997 ·Biopolymers ·David C. Dalgarno,Martyn C. Botfield,Richard J. Rickles	144
10	Identification of Itk/Tsk Src Homology 3 Domain Ligands 1996 ·Journal of Biological Chemistry ·Stephen C. Bunnell,(unknown),(unknown),Tomas Kirchhausen,Richard J. Rickles,Leslie J. Berg	155
11	Structure-Function Analysis of SH3 Domains: SH3 Binding Specificity Altered by Single Amino Acid Substitutions 1995 ·Molecular and Cellular Biology ·Zhigang Weng,Richard J. Rickles,Sibo Feng,Stéphane Richard,Andréy S. Shaw,Stuart L. Schreiber,Joan S. Brugge	111
12	Identification of Src, Fyn, and Lyn SH3-Binding Proteins: Implications for a Function of SH3 Domains 1994 ·Molecular and Cellular Biology ·Zhigang Weng,Sheila Μ. Thomas,Richard J. Rickles,Jennifer A. Taylor,Andrew W. Brauer,Cynthia Seidel‐Dugan,W. Matthew Michael,Gideon Dreyfuss,Joan S. Brugge	50
13	Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains. 1994 ·Molecular and Cellular Biology ·Zhen Weng,Sheila Μ. Thomas,Richard J. Rickles,Jacqueline Taylor,Andrew W. Brauer,Cynthia Seidel‐Dugan,(unknown),Gideon Dreyfuss,Joan S. Brugge	216
14	Overproduction and single-step purification of GAL4 fusion proteins from Escherichia coli 1993 ·Gene ·Richard J. Reece,Richard J. Rickles,Mark Ptashne	44
15	Transcription Factor Sp1 Is Important for Retinoic Acid-Induced Expression of the Tissue Plasminogen Activator Gene during F9 Teratocarcinoma Cell Differentiation 1990 ·Molecular and Cellular Biology ·Andrew L. Darrow,Richard J. Rickles,Lauren Pecorino,Sidney Strickland	5
16	Maintenance and use of F9 teratocarcinoma cells 1990 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Andrew L. Darrow,Richard J. Rickles,Sidney Strickland	34
17	Tissue plasminogen activator mRNA in murine tissues 1988 ·FEBS Letters ·Richard J. Rickles,Sidney Strickland	41
18	Anti-sense inhibition of tissue plasminogen activator production in differentiated F9 teratocarcinoma cells 1988 ·Developmental Biology ·Lauren Pecorino,Richard J. Rickles,Sidney Strickland	10
19	Chromosomal assignments of genes for tissue plasminogen activator and urokinase in mouse 1987 ·Somatic Cell and Molecular Genetics ·Bhanu Rajput,(unknown),Ann M. Killary,P.A. Lalley,Susan L. Naylor,Dominique Belin,Richard J. Rickles,Sidney Strickland	20
20	Analysis of histone gene expression during the cell cycle in HeLa cells by using cloned human histone genes. 1982 ·Proceedings of the National Academy of Sciences ·Richard J. Rickles,Farhad Marashi,Felipe Sierra,Susan J. Clark,J. R. E. Wells,Janet L. Stein,Gary Stein	81

About Richard J. Rickles

Richard J. Rickles is a scholar working on Cancer Research, Molecular Biology and Hematology, having authored 44 papers that have together received 4.3k indexed citations. Recurring topics across this work include Protease and Inhibitor Mechanisms (8 papers), Protein Kinase Regulation and GTPase Signaling (7 papers) and Peptidase Inhibition and Analysis (7 papers). The work is most often cited by research in Molecular Biology (3.3k citations), Immunology and Allergy (244 citations) and Cancer Research (559 citations). Richard J. Rickles has collaborated with scholars based in United States, Switzerland and Australia. Frequent co-authors include Sidney Strickland, Guang Hu, Gregory J. Hannon, Stephen J. Elledge, Andrew L. Darrow, Martyn C. Botfield, Joan S. Brugge, Frank Stegmeier, Stuart L. Schreiber and Alexis A. Borisy. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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