Philip Cohen

107.0k citations

489 papers · 89.2k indexed · 41 hit papers · h-index 143

Impact in

Molecular Biology top 0.01%
- Protein Kinase Regulation and GTPase Signaling
- PI3K/AKT/mTOR signaling in cancer
- Melanoma and MAPK Pathways
- Metabolism, Diabetes, and Cancer
- Wnt/β-catenin signaling in development and cancer
- Ubiquitin and proteasome pathways
- Ion channel regulation and function
- Mitochondrial Function and Pathology
Cell Biology top 0.01%

Papers in

Cell Biology 125
- Muscle metabolism and nutrition 45
Molecular Biology 394
- Protein Kinase Regulation and GTPase Signaling 124
- Melanoma and MAPK Pathways 53
- Mitochondrial Function and Pathology 52
- Metabolism, Diabetes, and Cancer 36
- Ubiquitin and proteasome pathways 35

Co-authors: Dario R. Alessi Sheelagh Frame Matilde Caivano Stephen Davies Helen Reddy Ana Cuenda Brian A. Hemmings Michel Goedert
Journals: European Journal of Biochemistry (81 papers)FEBS Letters (75 papers)Biochemical Journal (66 papers)Journal of Biological Chemistry (32 papers)Biochemical Society Transactions (23 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

Philip Cohen

483 papers receiving 86.7k citations

Hit Papers

15 papers align trajectories log scale

Kinase drug discovery 20 years after imatinib: progress and future directions 2021 · 670 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Nature Reviews Drug Discovery
2008 Nature
2007 Biochemical Journal
2004 Nature Reviews Drug Discovery
2003 Biochemical Journal
2002 Nature Cell Biology
2002 Nature Reviews Drug Discovery
2001 Molecular Cell
2001 Biochemical Journal
2001 European Journal of Biochemistry
2001 Nature Reviews Molecular Cell Biology
2001 Biochemical Journal
2000 Biochemical Journal
2000 Trends in Biochemical Sciences
2000 Biochemical Journal
1999 Biochemical Journal
1999 Journal of Biological Chemistry
1998 Current Opinion in Genetics & Development
1998 Science
1997 Journal of Biological Chemistry
1996 The EMBO Journal
1996 FEBS Letters
1996 The EMBO Journal
1996 The EMBO Journal
1995 Journal of Biological Chemistry
1994 Cell
1993 Trends in Biochemical Sciences
1993 Biochemical Journal
1992 Cell
1992 Biochemical Journal
1990 FEBS Letters
1989 Annual Review of Biochemistry
1989 Nature
1989 Journal of Biological Chemistry
1983 Science
1982 Nature
1982 FEBS Letters
1980 PubMed
1980 European Journal of Biochemistry
1978 FEBS Letters
1973 European Journal of Biochemistry

Peers

Countries citing papers authored by Philip Cohen

Since Specialization

Citations

This map shows the geographic impact of Philip Cohen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip Cohen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip Cohen more than expected).

Fields of papers citing papers by Philip Cohen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip Cohen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip Cohen. The network helps show where Philip Cohen may publish in the future.

Co-authors

The 25 scholars most cited alongside Philip Cohen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Philip Cohen Line = papers co-authored together Philip Cohen links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Discovery and functional analysis of a novel ALPK1 variant in ROSAH syndrome Open Biology ·Tom Snelling, Yu Yingying, Isabelle Jéru, Masahiro Niwano, Laurence Cuisset, Antoinette Perlat, J. DeKRAKER, Young Ju Oh, Caddigan and McHugh, Nicola T. Wood, Philip Cohen, Alban Ziegler	2024	6
2	Pacritinib abrogates the lupus phenotype in ABIN1[D485N] mice Lupus Science & Medicine ·Erica Johnson, G Pecchia, Sambit K. Nanda, Cheryl L. Scudamore, Philip Cohen	2023	0
3	HOIL‐1‐catalysed, ester‐linked ubiquitylation restricts IL‐18 signaling in cytotoxic T cells but promotes TLR signalling in macrophages FEBS Journal ·Erica Johnson, Jiazhen Zhang, Sambit K. Nanda, G Pecchia, Philip Cohen	2021	16
4	The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells Proceedings of the National Academy of Sciences ·Ian R. Kelsall, Jiazhen Zhang, Axel Knebel, J. Simon C. Arthur, Philip Cohen	2019	98
5	Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice Life Science Alliance ·Sambit K. Nanda, Erica Johnson, Francesco Marchesi, Marek Gierliński, 刘蓁, Katherine L. Lee, Stephen W. Wright, Vikram R. Rao, Philip Cohen, J. Simon C. Arthur	2019	13
6	Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling Proceedings of the National Academy of Sciences ·Sam Strickson, Christoph H. Emmerich, Eddy T. H. Goh, Jiazhen Zhang, Ian R. Kelsall, Thomas Macartney, C. James Hastie, Axel Knebel, Mark Peggie, Francesco Marchesi, J. Simon C. Arthur, Philip Cohen	2017	88
7	Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains Proceedings of the National Academy of Sciences ·Christoph H. Emmerich, Alban Ordureau, Sam Strickson, J. Simon C. Arthur, Patrick G. A. Pedrioli, David Komander, Philip Cohen	2013	346
8	Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles HAL (Le Centre pour la Communication Scientifique Directe) ·Fabrice Anizon, Rufine Akué‐Gédu, Lionel Nauton, Vincent Théry, Jenny Bain, Philip Cohen, Pascale Moreau	2011	1
9	IL–1β-stimulated activation of ERK1/2 and p38α MAPK mediates the transcriptional up-regulation of IL–6, IL–8 and GRO-α in HeLa cells Cellular Signalling ·Huei‐Ting Yang, Philip Cohen, Simon Rousseau	2007	49
10	The Electronic Discharge Summary - a Local Solution Succeeds Juan Fernando Mesa Calderón, C. Dong, Jordão Bragantini, P. K. Parshin, Philip Cohen	2003	2
11	MSK1 and MSK2 Are Required for the Mitogen- and Stress-Induced Phosphorylation of CREB and ATF1 in Fibroblasts Molecular and Cellular Biology ·Giselle R. Wiggin, Rocha Saavedra, Yadarat Inthaklhan, Yichun Yin, Philip Cohen, J. Simon C. Arthur	2002	368
12	K + channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK Pflügers Archiv - European Journal of Physiology ·Nikita Gamper, Sophie Fillon, Yuxi Feng, Nahal D Heydari, Donato O. Abaya, Guido Henke, Stephan M. Huber, Toshihide Kobayashi, Philip Cohen, Florian Läng	2002	65
13	Role of Mitogen-Activated Protein Kinase Cascades in Mediating Lipopolysaccharide-Stimulated Induction of Cyclooxygenase-2 and IL-1β in RAW264 Macrophages The Journal of Immunology ·Matilde Caivano, Philip Cohen	2000	193
14	Regions of the 110‐kDa Regulatory Subunit M₁₁₀ Required for Regulation of Myosin‐Light‐Chain‐Phosphatase Activity in Smooth Muscle European Journal of Biochemistry ·Philippe Gailly, R. J. H., Timothy Haystead, Andrew P. Somlyo, Patricia T.W. Cohen, Philip Cohen, Avril V. Somlyo	1996	48
15	Amino acid sequence and expression of the hepatic glycogen‐binding (G_L‐subunit of protein phosphatase‐1 FEBS Letters ·Martin Doherty, Greg B. G. Moorhead, Nick Morrice, Philip Cohen, Patricia T.W. Cohen, (unknown), (unknown)	1995	139
16	Phosphotyrosine Residues in the Nerve‐Growth‐Factor Receptor (Trk‐A) European Journal of Biochemistry ·Ruth Baxter, Philip Cohen, Axel Obermeier, Axel Ullrich, C. Peter Downes, Yair N. Doza	1995	47
17	Activation of the MAP kinase pathway by the protein kinase raf Cell ·Louise R. Howe, Sally J. Leevers, Néstor Gómez, Sara Nakielny, Philip Cohen, Christopher J. Marshall Hit paper breakdown →	1992	727
18	[36] Targeting subunits for protein phosphatases Methods in enzymology on CD-ROM/Methods in enzymology ·Michael J. Hubbard, Philip Cohen	1991	22
19	[37] Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle Methods in enzymology on CD-ROM/Methods in enzymology ·Philip Cohen, Susana Alemany, Jeff Barroso, J.W. Resink, Peter Strålfors, H.Y. Lim Tung	1988	397
20	The Role of Calmodulin in the Structure and Regulation of Phosphorylase Kinase from Rabbit Skeletal Muscle European Journal of Biochemistry ·Shirish Shenolikar, Patricia T.W. Cohen, (unknown), Philip Cohen, Angus C. Nairn, S V Perry	1979	227

About Philip Cohen

Philip Cohen is a scholar working on Cell Biology, Molecular Biology, Rheumatology, Aging and Cancer Research, having authored 489 papers that have together received 89.2k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (124 papers), Glycogen Storage Diseases and Myoclonus (61 papers), Melanoma and MAPK Pathways (53 papers), Mitochondrial Function and Pathology (52 papers), NF-κB Signaling Pathways (47 papers), Muscle metabolism and nutrition (45 papers), Metabolism, Diabetes, and Cancer (36 papers) and Ubiquitin and proteasome pathways (35 papers). The work is most often cited by research in Molecular Biology (67.4k citations), Cell Biology (13.5k citations), Aging (1.3k citations), Cancer Research (6.6k citations) and Cellular and Molecular Neuroscience (7.6k citations). Philip Cohen has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Dario R. Alessi, Sheelagh Frame, Matilde Caivano, Stephen Davies, Helen Reddy, Ana Cuenda, Brian A. Hemmings, Michel Goedert, Thomas S. Ingebritsen and James R. Woodgett. Their work appears in journals such as European Journal of Biochemistry, FEBS Letters, Biochemical Journal, Journal of Biological Chemistry and Biochemical Society Transactions.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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