Todd R. Golub

266.8k total citations · 40 hit papers
229 papers, 113.9k citations indexed

About

Todd R. Golub is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Todd R. Golub has authored 229 papers receiving a total of 113.9k indexed citations (citations by other indexed papers that have themselves been cited), including 171 papers in Molecular Biology, 59 papers in Cancer Research and 46 papers in Oncology. Recurrent topics in Todd R. Golub's work include Cancer Genomics and Diagnostics (28 papers), Acute Myeloid Leukemia Research (28 papers) and Gene expression and cancer classification (22 papers). Todd R. Golub is often cited by papers focused on Cancer Genomics and Diagnostics (28 papers), Acute Myeloid Leukemia Research (28 papers) and Gene expression and cancer classification (22 papers). Todd R. Golub collaborates with scholars based in United States, Canada and Germany. Todd R. Golub's co-authors include Eric S. Lander, Pablo Tamayo, Jill P. Mesirov, Benjamin L. Ebert, Aravind Subramanian, Vamsi K. Mootha, Sayan Mukherjee, Michael A. Gillette, Scott L. Pomeroy and Amanda G. Paulovich and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Todd R. Golub

221 papers receiving 111.8k citations

Hit Papers

Gene set enrichment analysis: A knowledge-based approach... 1994 2026 2004 2015 2005 1999 2005 2006 2022 10.0k 20.0k 30.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    2005 34.0k citations Aravind Subramanian, Pablo Tamayo et al. Proceedings of the National Academy of Sciences profile →
  2. Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
    1999 8.0k citations Todd R. Golub, Pablo Tamayo et al. Science profile →
  3. MicroRNA expression profiles classify human cancers
    2005 7.8k citations Jun Lü, Gad Getz et al. profile →
  4. The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
    2006 3.7k citations Justin Lamb, Aravind Subramanian et al. Science profile →
  5. Copper induces cell death by targeting lipoylated TCA cycle proteins
    2022 3.0k citations Sandro Santagata, Todd R. Golub et al. Science profile →
  6. Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation
    1999 2.1k citations Pablo Tamayo, Jill P. Mesirov et al. Proceedings of the National Academy of Sciences profile →
  7. Discovery and saturation analysis of cancer genes across 21 tumour types
    2014 2.1k citations Levi A. Garraway, Todd R. Golub et al. profile →
  8. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
    2001 2.0k citations Stefano Monti, Massimo Loda et al. Proceedings of the National Academy of Sciences profile →
  9. A molecular signature of metastasis in primary solid tumors
    2002 1.9k citations Todd R. Golub et al. Nature Genetics profile →
  10. Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
    2002 1.8k citations Margaret A. Shipp, Pablo Tamayo et al. profile →
  11. Gene expression correlates of clinical prostate cancer behavior
    2002 1.8k citations Phillip G. Febbo, Pablo Tamayo et al. Cancer Cell profile →
  12. Dissecting the Regulatory Circuitry of a Eukaryotic Genome
    1998 1.5k citations Todd R. Golub, Richard A. Young et al. profile →
  13. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
    2005 1.5k citations Jun Lü, Todd R. Golub et al. profile →
  14. Multiclass cancer diagnosis using tumor gene expression signatures
    2001 1.5k citations Pablo Tamayo, Sayan Mukherjee et al. Proceedings of the National Academy of Sciences profile →
  15. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
    2012 1.4k citations Shuji Ogino, Todd R. Golub et al. profile →
  16. Consensus Clustering: A Resampling-Based Method for Class Discovery and Visualization of Gene Expression Microarray Data
    2003 1.4k citations Stefano Monti, Pablo Tamayo et al. profile →
  17. Metagenes and molecular pattern discovery using matrix factorization
    2004 1.3k citations Jean-Philippe Brunet, Pablo Tamayo et al. Proceedings of the National Academy of Sciences profile →
  18. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
    2001 1.3k citations Scott A. Armstrong, Rob Pieters et al. Nature Genetics profile →
  19. Genomic analysis of metastasis reveals an essential role for RhoC
    2000 1.2k citations Todd R. Golub et al. profile →
  20. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
    2005 1.1k citations Levi A. Garraway, Mark A. Rubin et al. profile →
  21. Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9
    2006 1.0k citations David Twomey, William C. Hahn et al. profile →
  22. MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia
    2006 1.0k citations Benjamin L. Ebert, Todd R. Golub et al. profile →
  23. BRAF mutation predicts sensitivity to MEK inhibition
    2005 1.0k citations Levi A. Garraway, Gad Getz et al. profile →
  24. Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
    1994 933 citations Todd R. Golub et al. profile →
  25. Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma
    2010 928 citations Michael R. Green, Stefano Monti et al. Blood profile →
  26. Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma
    2009 872 citations Yujin Hoshida, Sebastian Nijman et al. Cancer Research profile →
  27. Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer
    2006 843 citations Todd R. Golub, Mark A. Rubin et al. Cancer Research profile →
  28. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
    2002 819 citations Donna Neuberg, Todd R. Golub et al. Cancer Cell profile →
  29. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
    2004 781 citations Pradip K. Majumder, Phillip G. Febbo et al. profile →
  30. Stem cell gene expression programs influence clinical outcome in human leukemia
    2011 740 citations Levi Waldron, Todd R. Golub et al. profile →
  31. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.
    2003 719 citations D.R. Mani, Pablo Tamayo et al. profile →
  32. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
    2000 667 citations Pablo Tamayo, Todd R. Golub et al. Proceedings of the National Academy of Sciences profile →
  33. Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
    2008 629 citations Benjamin L. Ebert, Pablo Tamayo et al. profile →
  34. Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
    1995 604 citations Todd R. Golub et al. Proceedings of the National Academy of Sciences profile →
  35. Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability
    2002 578 citations Todd R. Golub et al. profile →
  36. Chemosensitivity prediction by transcriptional profiling
    2001 532 citations Pablo Tamayo, Jill P. Mesirov et al. Proceedings of the National Academy of Sciences profile →
  37. Altered microRNA expression in human heart disease
    2007 518 citations Jun Lü, Todd R. Golub et al. profile →
  38. Patient-derived xenografts undergo mouse-specific tumor evolution
    2017 517 citations Uri Ben‐David, Gavin Ha et al. Nature Genetics profile →
  39. Mitochondrial metabolism promotes adaptation to proteotoxic stress
    2019 436 citations Aviad Tsherniak, Sandro Santagata et al. profile →
  40. A metastasis map of human cancer cell lines
    2020 272 citations Todd R. Golub et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Todd R. Golub United States 111 77.0k 27.5k 18.8k 13.7k 11.6k 229 113.9k
Gordon B. Mills United States 141 57.8k 0.8× 20.8k 0.8× 26.6k 1.4× 13.3k 1.0× 10.6k 0.9× 1.0k 89.6k
Benjamin L. Ebert United States 78 46.7k 0.6× 19.4k 0.7× 10.7k 0.6× 7.3k 0.5× 9.5k 0.8× 294 73.5k
Adrian L. Harris United Kingdom 164 64.9k 0.8× 45.7k 1.7× 34.9k 1.9× 13.0k 1.0× 10.5k 0.9× 1.2k 109.9k
Douglas Hanahan United States 109 79.7k 1.0× 36.5k 1.3× 43.8k 2.3× 12.6k 0.9× 19.2k 1.7× 230 137.2k
Gordon K. Smyth Australia 87 69.9k 0.9× 20.6k 0.7× 14.1k 0.8× 9.8k 0.7× 18.5k 1.6× 345 122.5k
Jill P. Mesirov United States 55 51.9k 0.7× 15.2k 0.6× 11.9k 0.6× 9.8k 0.7× 10.3k 0.9× 137 80.1k
Pablo Tamayo United States 52 48.4k 0.6× 14.4k 0.5× 11.6k 0.6× 9.9k 0.7× 9.9k 0.8× 149 74.2k
Rakesh K. Jain United States 170 56.7k 0.7× 27.5k 1.0× 34.7k 1.8× 17.1k 1.2× 14.2k 1.2× 862 134.8k
Eric S. Lander United States 178 145.6k 1.9× 34.7k 1.3× 18.9k 1.0× 11.4k 0.8× 17.0k 1.5× 408 222.1k
Chris Sander United States 119 69.7k 0.9× 26.3k 1.0× 13.4k 0.7× 10.6k 0.8× 6.5k 0.6× 308 93.4k

Countries citing papers authored by Todd R. Golub

Since Specialization
Citations

This map shows the geographic impact of Todd R. Golub's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Todd R. Golub with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Todd R. Golub more than expected).

Fields of papers citing papers by Todd R. Golub

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Todd R. Golub. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Todd R. Golub. The network helps show where Todd R. Golub may publish in the future.

Co-authorship network of co-authors of Todd R. Golub

This figure shows the co-authorship network connecting the top 25 collaborators of Todd R. Golub. A scholar is included among the top collaborators of Todd R. Golub based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Todd R. Golub. Todd R. Golub is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Xiong, Kan, Justin Rhoades, Timothy Blewett, et al.. (2021). Duplex-Repair enables highly accurate sequencing, despite DNA damage. Nucleic Acids Research. 50(1). e1–e1. 10 indexed citations
2.
Durbin, Adam D., Mark W. Zimmerman, Neekesh V. Dharia, et al.. (2018). Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nature Genetics. 50(9). 1240–1246. 145 indexed citations
3.
Ben‐David, Uri, Gavin Ha, Prasidda Khadka, et al.. (2016). The landscape of chromosomal aberrations in breast cancer mouse models reveals driver-specific routes to tumorigenesis. Nature Communications. 7(1). 12160–12160. 37 indexed citations
4.
Moskwa, Patryk, Pascal O. Zinn, Young Eun Choi, et al.. (2014). A Functional Screen Identifies miRs That Induce Radioresistance in Glioblastomas. Molecular Cancer Research. 12(12). 1767–1778. 24 indexed citations
5.
Santagata, Sandro, Marc L. Mendillo, Yun‐Chi Tang, et al.. (2013). Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State. Science. 341(6143). 1238303–1238303. 222 indexed citations
6.
Waldron, Levi, Shuji Ogino, Yujin Hoshida, et al.. (2012). Expression Profiling of Archival Tumors for Long-term Health Studies. Clinical Cancer Research. 18(22). 6136–6146. 25 indexed citations
7.
Green, Michael R., Stefano Monti, Riccardo Dalla‐Favera, et al.. (2011). Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program. Proceedings of the National Academy of Sciences. 108(7). 2873–2878. 42 indexed citations
8.
Guo, Shangqin, Jun Lü, Hao Zhang, et al.. (2010). MicroRNA miR-125a controls hematopoietic stem cell number. Proceedings of the National Academy of Sciences. 107(32). 14229–14234. 260 indexed citations
9.
Zimmer, Michael, Justin Lamb, Benjamin L. Ebert, et al.. (2010). The Connectivity Map Links Iron Regulatory Protein-1–Mediated Inhibition of Hypoxia-Inducible Factor-2a Translation to the Anti-inflammatory 15-deoxy-Δ12,14-Prostaglandin J2. Cancer Research. 70(8). 3071–3079. 38 indexed citations
10.
Ong, Shao‐En, Monica Schenone, Adam A. Margolin, et al.. (2009). Identifying the proteins to which small-molecule probes and drugs bind in cells. Proceedings of the National Academy of Sciences. 106(12). 4617–4622. 237 indexed citations
11.
Hoshida, Yujin, Sebastian Nijman, Masahiro Kobayashi, et al.. (2009). Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma. Cancer Research. 69(18). 7385–7392. 872 indexed citations breakdown →
12.
Lin, William M., Alissa C. Baker, Rameen Beroukhim, et al.. (2008). Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma. Cancer Research. 68(3). 664–673. 215 indexed citations
13.
Huang, Guosheng, Rosana Eisenberg, Min Yan, et al.. (2008). 15-Hydroxyprostaglandin Dehydrogenase is a Target of Hepatocyte Nuclear Factor 3β and a Tumor Suppressor in Lung Cancer. Cancer Research. 68(13). 5040–5048. 36 indexed citations
14.
Wei, Guo, David Twomey, Justin Lamb, et al.. (2006). Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance. Cancer Cell. 10(4). 331–342. 385 indexed citations
15.
Febbo, Phillip G., Aaron R. Thorner, Mark A. Rubin, et al.. (2006). Application of Oligonucleotide Microarrays to Assess the Biological Effects of Neoadjuvant Imatinib Mesylate Treatment for Localized Prostate Cancer. Clinical Cancer Research. 12(1). 152–158. 20 indexed citations
16.
Kobayashi, Susumu, Takeshi Shimamura, Stefano Monti, et al.. (2006). Transcriptional Profiling Identifies Cyclin D1 as a Critical Downstream Effector of Mutant Epidermal Growth Factor Receptor Signaling. Cancer Research. 66(23). 11389–11398. 98 indexed citations
17.
Brunet, Jean-Philippe, Pablo Tamayo, Todd R. Golub, & Jill P. Mesirov. (2004). Metagenes and molecular pattern discovery using matrix factorization. Proceedings of the National Academy of Sciences. 101(12). 4164–4169. 1310 indexed citations breakdown →
18.
Halmos, Balázs, Daniela S. Daniela Sanchez Bassères, Stefano Monti, et al.. (2004). A Transcriptional Profiling Study of CCAAT/Enhancer Binding Protein Targets Identifies Hepatocyte Nuclear Factor 3β as a Novel Tumor Suppressor in Lung Cancer. Cancer Research. 64(12). 4137–4147. 63 indexed citations
19.
Berger, Raanan, Phillip G. Febbo, Pradip K. Majumder, et al.. (2004). Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells. Cancer Research. 64(24). 8867–8875. 140 indexed citations
20.
Xu, Ke, Daniel C. Chung, Annegret Glasow, et al.. (2003). Dithiophenes potentiate differentiation of APL cells by lowering the threshold for ligand mediated co-repressor/co-activator exchange with RAR alpha and enhancing changes in ATRA regulated gene expression.. Blood. 102(11). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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