Todd R. Golub

266.8k citations

229 papers · 113.9k indexed · 40 hit papers · h-index 111

Molecular Biology top 0.01%
Cancer Research top 0.01%
Oncology top 0.02%
Pulmonary and Respiratory Medicine top 0.02%
Immunology top 0.05%

Co-authors: Eric S. Lander Pablo Tamayo Jill P. Mesirov Benjamin L. Ebert Aravind Subramanian Vamsi K. Mootha Sayan Mukherjee Michael A. Gillette
Topics: Cancer Genomics and Diagnostics (28 papers)Acute Myeloid Leukemia Research (28 papers)Gene expression and cancer classification (22 papers)
Cited by: Cancer Research Molecular Biology Hematology
Journals: Nature Science Cell
Partner nations: United States Canada Germany

In The Last Decade

Todd R. Golub

221 papers receiving 111.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

2005 34.0k citations Aravind Subramanian, Pablo Tamayo et al. Proceedings of the National Academy of Sciences profile →
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 8.0k citations Todd R. Golub, Pablo Tamayo et al. Science profile →
MicroRNA expression profiles classify human cancers

2005 7.8k citations Jun Lü, Gad Getz et al. profile →
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

2006 3.7k citations Justin Lamb, Aravind Subramanian et al. Science profile →
Copper induces cell death by targeting lipoylated TCA cycle proteins

2022 3.0k citations Sandro Santagata, Todd R. Golub et al. Science profile →
Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation

1999 2.1k citations Pablo Tamayo, Jill P. Mesirov et al. Proceedings of the National Academy of Sciences profile →
Discovery and saturation analysis of cancer genes across 21 tumour types

2014 2.1k citations Levi A. Garraway, Todd R. Golub et al. profile →
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

2001 2.0k citations Stefano Monti, Massimo Loda et al. Proceedings of the National Academy of Sciences profile →
A molecular signature of metastasis in primary solid tumors

2002 1.9k citations Todd R. Golub et al. Nature Genetics profile →
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

2002 1.8k citations Margaret A. Shipp, Pablo Tamayo et al. profile →
Gene expression correlates of clinical prostate cancer behavior

2002 1.8k citations Phillip G. Febbo, Pablo Tamayo et al. profile →
Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 1.5k citations Todd R. Golub, Richard A. Young et al. profile →
Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

2005 1.5k citations Jun Lü, Todd R. Golub et al. profile →
Multiclass cancer diagnosis using tumor gene expression signatures

2001 1.5k citations Pablo Tamayo, Sayan Mukherjee et al. Proceedings of the National Academy of Sciences profile →
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

2012 1.4k citations Jinyan Du, Shuji Ogino et al. profile →
Consensus Clustering: A Resampling-Based Method for Class Discovery and Visualization of Gene Expression Microarray Data

2003 1.4k citations Stefano Monti, Pablo Tamayo et al. profile →
Metagenes and molecular pattern discovery using matrix factorization

2004 1.3k citations Jean-Philippe Brunet, Pablo Tamayo et al. Proceedings of the National Academy of Sciences profile →
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

2001 1.3k citations Todd R. Golub et al. Nature Genetics profile →
Genomic analysis of metastasis reveals an essential role for RhoC

2000 1.2k citations Todd R. Golub et al. profile →
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

2005 1.1k citations Levi A. Garraway, Mark A. Rubin et al. profile →
Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

2006 1.0k citations William C. Hahn, Todd R. Golub et al. profile →
MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia

2006 1.0k citations Benjamin L. Ebert, Todd R. Golub et al. profile →
BRAF mutation predicts sensitivity to MEK inhibition

2005 1.0k citations Levi A. Garraway, Gad Getz et al. profile →
Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

1994 933 citations Todd R. Golub et al. profile →
Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

2010 928 citations Michael R. Green, Stefano Monti et al. profile →
Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma

2009 872 citations Yujin Hoshida, Sebastian Nijman et al. Cancer Research profile →
Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer

2006 843 citations Todd R. Golub, Mark A. Rubin et al. Cancer Research profile →
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

2002 819 citations Donna Neuberg, Todd R. Golub et al. profile →
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

2004 781 citations Pradip K. Majumder, Phillip G. Febbo et al. profile →
Stem cell gene expression programs influence clinical outcome in human leukemia

2011 740 citations Levi Waldron, Todd R. Golub et al. profile →
Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.

2003 719 citations D.R. Mani, Pablo Tamayo et al. profile →
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

2000 667 citations Pablo Tamayo, Todd R. Golub et al. Proceedings of the National Academy of Sciences profile →
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

2008 629 citations Benjamin L. Ebert, Pablo Tamayo et al. profile →
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.

1995 604 citations Todd R. Golub et al. Proceedings of the National Academy of Sciences profile →
Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability

2002 578 citations Jinyan Du, Todd R. Golub et al. profile →
Chemosensitivity prediction by transcriptional profiling

2001 532 citations Pablo Tamayo, Jill P. Mesirov et al. Proceedings of the National Academy of Sciences profile →
Altered microRNA expression in human heart disease

2007 518 citations Jun Lü, Todd R. Golub et al. profile →
Patient-derived xenografts undergo mouse-specific tumor evolution

2017 517 citations Bang Wong, Jesse S. Boehm et al. Nature Genetics profile →
Mitochondrial metabolism promotes adaptation to proteotoxic stress

2019 436 citations Aviad Tsherniak, Sandro Santagata et al. profile →
A metastasis map of human cancer cell lines

2020 272 citations Todd R. Golub et al. profile →

Peers

Countries citing papers authored by Todd R. Golub

Since Specialization

Citations

This map shows the geographic impact of Todd R. Golub's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Todd R. Golub with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Todd R. Golub more than expected).

Fields of papers citing papers by Todd R. Golub

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Todd R. Golub. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Todd R. Golub. The network helps show where Todd R. Golub may publish in the future.

Co-authorship network of co-authors of Todd R. Golub

This figure shows the co-authorship network connecting the top 25 collaborators of Todd R. Golub. A scholar is included among the top collaborators of Todd R. Golub based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Todd R. Golub. Todd R. Golub is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Systematic profiling of conditional degron tag technologies for target validation studies 2022 ·Nature Communications ·Daniel P. Bondeson,(unknown),(unknown),(unknown),Thomas C. Atack,Nolan Bick,(unknown),Andrew A. Guirguis,Jason J. Kwon,(unknown),(unknown),Brenton R. Paolella,Kevin Tran,(unknown),Francisca Vázquez,Zuzana Tóthová,Todd R. Golub,William R. Sellers,Alessandra Ianari	19
2	Duplex-Repair enables highly accurate sequencing, despite DNA damage 2021 ·Nucleic Acids Research ·Kan Xiong,(unknown),Justin Rhoades,Timothy Blewett,Ruolin Liu,Jin H. Bae,(unknown),G. Mike Makrigiorgos,Todd R. Golub,Viktor A. Adalsteinsson	10
3	Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry 2018 ·Nature Genetics ·Adam D. Durbin,Mark W. Zimmerman,Neekesh V. Dharia,Brian J. Abraham,Amanda Balboni Iniguez,Nina Weichert‐Leahey,Shuning He,John M. Krill-Burger,David E. Root,Francisca Vázquez,Aviad Tsherniak,William C. Hahn,Todd R. Golub,Richard A. Young,A. Thomas Look,Kimberly Stegmaier	145
4	A Functional Screen Identifies miRs That Induce Radioresistance in Glioblastomas 2014 ·Molecular Cancer Research ·Patryk Moskwa,Pascal O. Zinn,Young Eun Choi,Sachet A. Shukla,Wojciech Fendler,Clark C. Chen,Jun Lü,Todd R. Golub,Anita B. Hjelmeland,Dipanjan Chowdhury	24
5	Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State 2013 ·Science ·Sandro Santagata,Marc L. Mendillo,Yun‐Chi Tang,Aravind Subramanian,Casey C. Perley,Stéphane P. Roche,Bang Wong,Rajiv Narayan,(unknown),Martina Koeva,Angelika Amon,Todd R. Golub,John A. Porco,Luke Whitesell,Susan Lindquist	222
6	Expression Profiling of Archival Tumors for Long-term Health Studies 2012 ·Clinical Cancer Research ·Levi Waldron,Shuji Ogino,Yujin Hoshida,Kaori Shima,Amy E. McCart Reed,Peter T. Simpson,Yoshifumi Baba,Katsuhiko Nosho,Nicola Segata,Ana Cristina Vargas,Margaret C. Cummings,Sunil R. Lakhani,Gregory J. Kirkner,Edward L. Giovannucci,John Quackenbush,Todd R. Golub,Charles S. Fuchs,Giovanni Parmigiani,Curtis Huttenhower	25
7	Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program 2011 ·Proceedings of the National Academy of Sciences ·Michael R. Green,Stefano Monti,Riccardo Dalla‐Favera,Laura Pasqualucci,Nicole C. Walsh,Marc Schmidt‐Supprian,Jeffery L. Kutok,Scott J. Rodig,Donna Neuberg,Klaus Rajewsky,Todd R. Golub,Frederick W. Alt,Margaret A. Shipp,John Manis	42
8	Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers 2011 ·Cancer Discovery ·Hiu Wing Cheung,Jinyan Du,Jesse S. Boehm,Frank He,Barbara A. Weir,Xiaoxing Wang,Mohit Butaney,Lecia V. Sequist,Biao Luo,Jeffrey A. Engelman,David E. Root,Matthew Meyerson,Todd R. Golub,Pasi A. Jänne,William C. Hahn	110
9	MicroRNA miR-125a controls hematopoietic stem cell number 2010 ·Proceedings of the National Academy of Sciences ·Shangqin Guo,Jun Lü,(unknown),Hao Zhang,(unknown),Michelle C. Fox,Louise E. Purton,(unknown),Bradley S. Cobb,Matthias Merkenschlager,Todd R. Golub,David T. Scadden	260
10	The Connectivity Map Links Iron Regulatory Protein-1–Mediated Inhibition of Hypoxia-Inducible Factor-2a Translation to the Anti-inflammatory 15-deoxy-Δ12,14-Prostaglandin J2 2010 ·Cancer Research ·Michael Zimmer,Justin Lamb,Benjamin L. Ebert,Mary C. Lynch,Christopher R. Neil,Emmett V. Schmidt,Todd R. Golub,Othon Iliopoulos	38
11	Molecular sampling of prostate cancer: a dilemma for predicting disease progression 2010 ·SHILAP Revista de lepidopterología ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Philip W. Kantoff,Meir J. Stampfer,(unknown),Eberhard Varenhorst,(unknown),Mark Gerstein,Todd R. Golub,Mark A. Rubin,Ove Andrén	178
12	Identifying the proteins to which small-molecule probes and drugs bind in cells 2009 ·Proceedings of the National Academy of Sciences ·Shao‐En Ong,Monica Schenone,Adam A. Margolin,Xiaoyu Li,(unknown),Mary Kathryn Doud,D.R. Mani,Letian Kuai,Xiang Wang,John L. Wood,Nicola Tolliday,Angela N. Koehler,Lisa A. Marcaurelle,Todd R. Golub,Robert J. Gould,Stuart L. Schreiber,Steven A. Carr	237
13	Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinomabreakdown → 2009 ·Cancer Research ·Yujin Hoshida,Sebastian Nijman,Masahiro Kobayashi,Jennifer A. Chan,(unknown),Derek Y. Chiang,Augusto Villanueva,Philippa Newell,Kenji Ikeda,Masaji Hashimoto,Goro Watanabe,Stacey Gabriel,Scott L. Friedman,Hiromitsu Kumada,Josep M. Llovet,Todd R. Golub	872
14	15-Hydroxyprostaglandin Dehydrogenase is a Target of Hepatocyte Nuclear Factor 3β and a Tumor Suppressor in Lung Cancer 2008 ·Cancer Research ·Guosheng Huang,Rosana Eisenberg,Min Yan,Stefano Monti,Earl Lawrence,Pingfu Fu,(unknown),Ester Löwenberg,Todd R. Golub,Jaime R. Merchan,Daniel G. Tenen,Sanford D. Markowitz,Balázs Halmos	36
15	Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma 2008 ·Cancer Research ·William M. Lin,Alissa C. Baker,Rameen Beroukhim,Wendy Winckler,Whei Feng,(unknown),Elisabeth Laine,Heidi Greulich,Hsiuyi Tseng,Casey Gates,F. Stephen Hodi,Glenn Dranoff,William R. Sellers,Roman K. Thomas,Matthew Meyerson,Todd R. Golub,Reinhard Dummer,Meenhard Herlyn,Gad Getz,Levi A. Garraway	215
16	Application of Oligonucleotide Microarrays to Assess the Biological Effects of Neoadjuvant Imatinib Mesylate Treatment for Localized Prostate Cancer 2006 ·Clinical Cancer Research ·Phillip G. Febbo,Aaron R. Thorner,Mark A. Rubin,Massimo Loda,Philip W. Kantoff,William Oh,Todd R. Golub,Daniel J. George	20
17	Transcriptional Profiling Identifies Cyclin D1 as a Critical Downstream Effector of Mutant Epidermal Growth Factor Receptor Signaling 2006 ·Cancer Research ·Susumu Kobayashi,Takeshi Shimamura,Stefano Monti,Ulrich Steidl,Christopher J. Hetherington,April M. Lowell,Todd R. Golub,Matthew Meyerson,Daniel G. Tenen,Geoffrey I. Shapiro,Balázs Halmos	98
18	Metagenes and molecular pattern discovery using matrix factorizationbreakdown → 2004 ·Proceedings of the National Academy of Sciences ·Jean-Philippe Brunet,Pablo Tamayo,Todd R. Golub,Jill P. Mesirov	1310
19	A Transcriptional Profiling Study of CCAAT/Enhancer Binding Protein Targets Identifies Hepatocyte Nuclear Factor 3β as a Novel Tumor Suppressor in Lung Cancer 2004 ·Cancer Research ·Balázs Halmos,Daniela S. Daniela Sanchez Bassères,Stefano Monti,(unknown),Tajhal Dayaram,Katalin Ferenczi,Bas J. Wouters,Claudia S. Huettner,Todd R. Golub,Daniel G. Tenen	63
20	Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells 2004 ·Cancer Research ·Raanan Berger,Phillip G. Febbo,Pradip K. Majumder,Jean J. Zhao,Sayan Mukherjee,Sabina Signoretti,Katrina Campbell,William R. Sellers,Thomas M. Roberts,Massimo Loda,Todd R. Golub,William C. Hahn	140

About Todd R. Golub

Todd R. Golub is a scholar working on Cancer Research, Hematology and Molecular Biology, having authored 229 papers that have together received 113.9k indexed citations. Recurring topics across this work include Cancer Genomics and Diagnostics (28 papers), Acute Myeloid Leukemia Research (28 papers) and Gene expression and cancer classification (22 papers). The work is most often cited by research in Cancer Research (27.5k citations), Molecular Biology (77.0k citations) and Hematology (8.9k citations). Todd R. Golub has collaborated with scholars based in United States, Canada and Germany. Frequent co-authors include Eric S. Lander, Pablo Tamayo, Jill P. Mesirov, Benjamin L. Ebert, Aravind Subramanian, Vamsi K. Mootha, Sayan Mukherjee, Michael A. Gillette, Scott L. Pomeroy and Amanda G. Paulovich. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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