Joan S. Brugge

55.4k total citations · 20 hit papers
259 papers, 41.9k citations indexed

About

Joan S. Brugge is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Joan S. Brugge has authored 259 papers receiving a total of 41.9k indexed citations (citations by other indexed papers that have themselves been cited), including 163 papers in Molecular Biology, 82 papers in Oncology and 54 papers in Cell Biology. Recurrent topics in Joan S. Brugge's work include Cell Adhesion Molecules Research (52 papers), Virus-based gene therapy research (41 papers) and Cancer Cells and Metastasis (35 papers). Joan S. Brugge is often cited by papers focused on Cell Adhesion Molecules Research (52 papers), Virus-based gene therapy research (41 papers) and Cancer Cells and Metastasis (35 papers). Joan S. Brugge collaborates with scholars based in United States, Canada and Japan. Joan S. Brugge's co-authors include Edwin Clark, Sheila Μ. Thomas, Jayanta Debnath, Senthil K. Muthuswamy, Raymond L. Erikson, Sanford J. Shattil, Cindy K. Miranti, Michael Overholtzer, Gordon B. Mills and Richard Sever and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Joan S. Brugge

256 papers receiving 40.5k citations

Hit Papers

Integrins and Signal Transduction Pathways: the Road Taken 1977 2026 1993 2009 1995 1997 2003 1992 2005 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Integrins and Signal Transduction Pathways: the Road Taken
    1995 2.6k citations Joan S. Brugge et al. profile →
  2. CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
    1997 2.1k citations Joan S. Brugge et al. profile →
  3. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    2003 1.6k citations Jayanta Debnath, Senthil K. Muthuswamy et al. profile →
  4. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
    1992 893 citations Joan S. Brugge et al. Nature profile →
  5. Modelling glandular epithelial cancers in three-dimensional cultures
    2005 812 citations Jayanta Debnath, Joan S. Brugge profile →
  6. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
    2009 808 citations Alexandra Grassian, Joan S. Brugge et al. Nature profile →
  7. Identification of a transformation-specific antigen induced by an avian sarcoma virus
    1977 801 citations Joan S. Brugge et al. Nature profile →
  8. Transforming properties of YAP , a candidate oncogene on the chromosome 11q22 amplicon
    2006 748 citations Joan S. Brugge et al. Proceedings of the National Academy of Sciences profile →
  9. Signal Transduction in Cancer
    2015 675 citations Joan S. Brugge et al. profile →
  10. Sensing the environment: a historical perspective on integrin signal transduction
    2002 672 citations Joan S. Brugge et al. Nature Cell Biology profile →
  11. Engineering tumors with 3D scaffolds
    2007 666 citations Joan S. Brugge et al. profile →
  12. Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases
    1992 641 citations Joan S. Brugge et al. Cell profile →
  13. Mutant p53 Drives Invasion by Promoting Integrin Recycling
    2009 641 citations Marcin Iwanicki, Joan S. Brugge et al. Cell profile →
  14. The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini
    2002 624 citations Jayanta Debnath, Nicole L. Collins et al. Cell profile →
  15. Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets.
    1992 592 citations Joan S. Brugge et al. The Journal of Cell Biology profile →
  16. A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion
    2007 547 citations Ghassan Mouneimne, Joan S. Brugge et al. Cell profile →
  17. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
    1995 517 citations Joan S. Brugge et al. Nature profile →
  18. Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases
    1998 513 citations Joan S. Brugge et al. The Journal of Cell Biology profile →
  19. Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses
    1983 506 citations Joan S. Brugge et al. profile →
  20. Therapy resistance: opportunities created by adaptive responses to targeted therapies in cancer
    2022 212 citations Joan S. Brugge, Gordon B. Mills et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Joan S. Brugge United States 111 25.6k 10.2k 9.5k 7.4k 5.2k 259 41.9k
J. Silvio Gutkind United States 121 33.7k 1.3× 11.5k 1.1× 7.8k 0.8× 3.8k 0.5× 6.9k 1.3× 582 52.2k
David A. Cheresh United States 109 28.3k 1.1× 10.3k 1.0× 7.6k 0.8× 18.3k 2.5× 6.5k 1.3× 245 48.7k
Meenhard Herlyn United States 110 26.4k 1.0× 17.1k 1.7× 6.7k 0.7× 3.9k 0.5× 8.6k 1.7× 545 42.8k
Anne J. Ridley United Kingdom 95 26.0k 1.0× 5.7k 0.6× 16.4k 1.7× 7.2k 1.0× 6.3k 1.2× 304 43.9k
Lena Claesson‐Welsh Sweden 87 22.2k 0.9× 6.9k 0.7× 4.8k 0.5× 3.5k 0.5× 3.5k 0.7× 256 32.3k
Mina J. Bissell United States 113 22.8k 0.9× 20.1k 2.0× 10.4k 1.1× 7.0k 0.9× 4.3k 0.8× 372 48.1k
Alan Hall United Kingdom 88 32.4k 1.3× 5.9k 0.6× 20.4k 2.1× 6.6k 0.9× 5.7k 1.1× 162 48.7k
Channing J. Der United States 111 36.2k 1.4× 12.7k 1.2× 10.6k 1.1× 2.9k 0.4× 4.4k 0.8× 406 48.3k
Jean Paul Thiery France 108 34.1k 1.3× 19.4k 1.9× 9.5k 1.0× 5.2k 0.7× 4.5k 0.9× 553 55.8k
Brian Seed United States 77 17.8k 0.7× 5.0k 0.5× 4.5k 0.5× 5.2k 0.7× 11.8k 2.3× 155 33.2k

Countries citing papers authored by Joan S. Brugge

Since Specialization
Citations

This map shows the geographic impact of Joan S. Brugge's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joan S. Brugge with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joan S. Brugge more than expected).

Fields of papers citing papers by Joan S. Brugge

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joan S. Brugge. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joan S. Brugge. The network helps show where Joan S. Brugge may publish in the future.

Co-authorship network of co-authors of Joan S. Brugge

This figure shows the co-authorship network connecting the top 25 collaborators of Joan S. Brugge. A scholar is included among the top collaborators of Joan S. Brugge based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joan S. Brugge. Joan S. Brugge is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Silvestri, F, Michael Oliphant, Dennis P. Orgill, et al.. (2024). Breast organoid suspension cultures maintain long-term estrogen receptor expression and responsiveness. npj Breast Cancer. 10(1). 107–107. 3 indexed citations
2.
Gray, G. Kenneth, Li Ren Kong, Komal Gupta, et al.. (2023). A transcriptional response to replication stress selectively expands a subset of Brca2-mutant mammary epithelial cells. Nature Communications. 14(1). 5206–5206. 3 indexed citations
3.
Takahashi, Nobuaki, Hsing‐Yu Chen, Isaac S. Harris, et al.. (2018). Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell. 33(6). 985–1003.e7. 201 indexed citations
4.
Muranen, Taru, Marcin Iwanicki, Natasha Curry, et al.. (2017). Starved epithelial cells uptake extracellular matrix for survival. Nature Communications. 8(1). 13989–13989. 86 indexed citations
5.
Stover, Daniel G., Jonathan L. Coloff, William T. Barry, et al.. (2016). The Role of Proliferation in Determining Response to Neoadjuvant Chemotherapy in Breast Cancer: A Gene Expression–Based Meta-Analysis. Clinical Cancer Research. 22(24). 6039–6050. 43 indexed citations
6.
Muranen, Taru, Laura M. Selfors, Julie Hwang, et al.. (2016). ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP. Cancer Research. 76(24). 7168–7180. 53 indexed citations
7.
Godinho, Susana A., Remigio Picone, Mithila Burute, et al.. (2014). Oncogene-like induction of cellular invasion from centrosome amplification. Nature. 510(7503). 167–171. 306 indexed citations
8.
Vakifahmetoglu-Norberg, Helin, Minsu Kim, Hongguang Xia, et al.. (2013). Chaperone-mediated autophagy degrades mutant p53. Genes & Development. 27(15). 1718–1730. 168 indexed citations
9.
Ng, Mei Rosa, Achim Besser, Gaudenz Danuser, & Joan S. Brugge. (2012). Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility. The Journal of Cell Biology. 199(3). 545–563. 244 indexed citations
10.
Grassian, Alexandra, Christian M. Metallo, Jonathan L. Coloff, Gregory Stephanopoulos, & Joan S. Brugge. (2011). Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Genes & Development. 25(16). 1716–1733. 146 indexed citations
11.
Iwanicki, Marcin, Rachel A. Davidowitz, Mei Rosa Ng, et al.. (2011). Ovarian Cancer Spheroids Use Myosin-Generated Force to Clear the Mesothelium. Cancer Discovery. 1(2). 144–157. 246 indexed citations
12.
Xian, Wa, Leontios Pappas, Laura M. Selfors, et al.. (2009). Fibroblast Growth Factor Receptor 1–Transformed Mammary Epithelial Cells Are Dependent on RSK Activity for Growth and Survival. Cancer Research. 69(6). 2244–2251. 61 indexed citations
13.
Simpson, Kaylene J., Laura M. Selfors, James T. Bui, et al.. (2008). Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nature Cell Biology. 10(9). 1027–1038. 327 indexed citations
14.
Mouneimne, Ghassan & Joan S. Brugge. (2007). Tensins: A New Switch in Cell Migration. Developmental Cell. 13(3). 317–319. 17 indexed citations
15.
Reginato, Mauricio J., et al.. (2004). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro. Proceedings of the National Academy of Sciences. 101(10). 3438–3443. 210 indexed citations
16.
Seton-Rogers, Sarah, Yu Lu, Lisa M. Hines, et al.. (2004). Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells. Proceedings of the National Academy of Sciences. 101(5). 1257–1262. 184 indexed citations
17.
Arias‐Salgado, Elena G., et al.. (2003). Src kinase activation by direct interaction with the integrin β cytoplasmic domain. Proceedings of the National Academy of Sciences. 100(23). 13298–13302. 448 indexed citations
18.
Debnath, Jayanta, et al.. (2002). The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini. Cell. 111(1). 29–40. 624 indexed citations breakdown →
19.
Rivera, Victor M. & Joan S. Brugge. (1995). Clustering of Syk Is Sufficient To Induce Tyrosine Phosphorylation and Release of Allergic Mediators from Rat Basophilic Leukemia Cells. Molecular and Cellular Biology. 15(3). 1582–1590. 60 indexed citations
20.
Weng, Zhigang, Richard J. Rickles, Sibo Feng, et al.. (1995). Structure-Function Analysis of SH3 Domains: SH3 Binding Specificity Altered by Single Amino Acid Substitutions. Molecular and Cellular Biology. 15(10). 5627–5634. 111 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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