Stephen J. Haggarty

32.9k total citations · 9 hit papers
140 papers, 19.0k citations indexed

About

Stephen J. Haggarty is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience. According to data from OpenAlex, Stephen J. Haggarty has authored 140 papers receiving a total of 19.0k indexed citations (citations by other indexed papers that have themselves been cited), including 113 papers in Molecular Biology, 28 papers in Genetics and 25 papers in Cellular and Molecular Neuroscience. Recurrent topics in Stephen J. Haggarty's work include Histone Deacetylase Inhibitors Research (41 papers), Protein Degradation and Inhibitors (28 papers) and Genetics and Neurodevelopmental Disorders (26 papers). Stephen J. Haggarty is often cited by papers focused on Histone Deacetylase Inhibitors Research (41 papers), Protein Degradation and Inhibitors (28 papers) and Genetics and Neurodevelopmental Disorders (26 papers). Stephen J. Haggarty collaborates with scholars based in United States, Germany and Canada. Stephen J. Haggarty's co-authors include Stuart L. Schreiber, Timothy J. Mitchison, Randall W. King, Thomas U. Mayer, Ralph Mazitschek, Tarun M. Kapoor, Kathryn M. Koeller, Jason Chun Yu Wong, Paul A. Clemons and Kenneth N. Ross and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Stephen J. Haggarty

139 papers receiving 18.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

2006 3.7k citations Stephen J. Haggarty, Paul A. Clemons et al. profile →
Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

1999 1.5k citations Stephen J. Haggarty, Stuart L. Schreiber et al. profile →
HDAC2 negatively regulates memory formation and synaptic plasticity

2009 1.3k citations Stephen J. Haggarty, Nadine F. Joseph et al. profile →
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

2003 861 citations Stephen J. Haggarty, Stuart L. Schreiber et al. Proceedings of the National Academy of Sciences profile →
An epigenetic blockade of cognitive functions in the neurodegenerating brain

2012 638 citations Jinsoo Seo, Daniel M. Fass et al. profile →
Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

2009 635 citations Stephen J. Haggarty et al. profile →
Chemical phylogenetics of histone deacetylases

2010 581 citations Stephen J. Haggarty, Ralph Mazitschek et al. profile →
Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

2010 572 citations Stephen J. Haggarty et al. profile →
Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

2009 557 citations Daniel M. Fass, Stephen J. Haggarty et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Stephen J. Haggarty United States	56	13.4k	2.8k	2.5k	2.1k	1.8k	140	19.0k
Jackie D. Corbin United States	84	15.1k 1.1×	1.8k 0.6×	3.4k 1.3×	1.6k 0.8×	1.0k 0.6×	261	22.6k
Christian Behl Germany	68	7.0k 0.5×	2.0k 0.7×	3.5k 1.4×	1.7k 0.8×	713 0.4×	239	18.1k
Hermona Soreq Israel	75	12.7k 1.0×	1.2k 0.4×	2.7k 1.1×	738 0.4×	1.3k 0.7×	416	22.6k
Peter S. Klein United States	57	9.5k 0.7×	2.3k 0.8×	2.2k 0.9×	1.7k 0.8×	1.1k 0.6×	125	14.7k
Richard S. Jope United States	75	12.8k 1.0×	3.2k 1.1×	6.6k 2.6×	1.9k 0.9×	1.5k 0.8×	251	23.0k
Michael Spedding France	65	11.7k 0.9×	1.2k 0.4×	8.4k 3.4×	643 0.3×	1.5k 0.8×	231	24.4k
Keqiang Ye United States	71	9.0k 0.7×	995 0.4×	3.8k 1.5×	3.8k 1.8×	1.8k 1.0×	244	17.1k
Masatoshi Hagiwara Japan	62	11.6k 0.9×	1.5k 0.5×	2.3k 0.9×	1.5k 0.7×	1.5k 0.8×	301	16.4k
James R. Woodgett Canada	108	35.7k 2.7×	4.3k 1.5×	5.7k 2.3×	5.8k 2.8×	5.8k 3.2×	293	47.6k
Craig J. Thomas United States	61	7.0k 0.5×	825 0.3×	1.8k 0.7×	460 0.2×	1.6k 0.9×	250	15.2k

Countries citing papers authored by Stephen J. Haggarty

Since Specialization

Citations

This map shows the geographic impact of Stephen J. Haggarty's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen J. Haggarty with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen J. Haggarty more than expected).

Fields of papers citing papers by Stephen J. Haggarty

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen J. Haggarty. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen J. Haggarty. The network helps show where Stephen J. Haggarty may publish in the future.

Co-authorship network of co-authors of Stephen J. Haggarty

This figure shows the co-authorship network connecting the top 25 collaborators of Stephen J. Haggarty. A scholar is included among the top collaborators of Stephen J. Haggarty based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephen J. Haggarty. Stephen J. Haggarty is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cenik, Basar, Jue Liang, Daniel M. Fass, et al.. (2024). Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency. Nature Communications. 15(1). 6125–6125. 3 indexed citations

Paulo, João A., et al.. (2024). Dissecting OGT’s TPR domain to identify determinants of cellular function. Proceedings of the National Academy of Sciences. 121(22). e2401729121–e2401729121. 7 indexed citations

Nguyen, Lien D., Zhiyun Wei, M. Catarina Silva, et al.. (2023). Small molecule regulators of microRNAs identified by high-throughput screen coupled with high-throughput sequencing. Nature Communications. 14(1). 7575–7575. 31 indexed citations

Alural, Begüm, Melissa L. Perreault, Stephen J. Haggarty, et al.. (2023). Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiation. Molecular Psychiatry. 28(12). 5237–5250. 12 indexed citations

Pao, Ping‐Chieh, Jinsoo Seo, Audrey Lee, et al.. (2023). A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes. Proceedings of the National Academy of Sciences. 120(16). e2217864120–e2217864120. 32 indexed citations

Jäntti, Maria, Juha R. Savinainen, Elena Puris, et al.. (2023). A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy. Science Translational Medicine. 15(691). eabq2915–eabq2915. 17 indexed citations

Patnaik, Debasis, Ping‐Chieh Pao, Wen‐Ning Zhao, et al.. (2021). Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration. ACS Chemical Neuroscience. 12(2). 271–284. 19 indexed citations

Bai, Ping, Yu Lan, Debasis Patnaik, et al.. (2021). Design, Synthesis, and Evaluation of Thienodiazepine Derivatives as Positron Emission Tomography Imaging Probes for Bromodomain and Extra-Terminal Domain Family Proteins. Journal of Medicinal Chemistry. 64(19). 14745–14756. 16 indexed citations

Tyler, Marshall, Debasis Patnaik, Hendrik Wesseling, et al.. (2021). Phosphorylation‐dependent control of Activity‐regulated cytoskeleton‐associated protein (Arc) protein by TNIK. Journal of Neurochemistry. 158(5). 1058–1073. 8 indexed citations

10.

Pao, Ping‐Chieh, Debasis Patnaik, L. Ashley Watson, et al.. (2020). HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease. Nature Communications. 11(1). 2484–2484. 157 indexed citations

11.

Haggarty, Stephen J., et al.. (2020). Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies. International Journal of Molecular Sciences. 21(23). 8948–8948. 60 indexed citations

12.

Patnaik, Debasis, Joshua A. Bishop, Robert M. Bigsby, et al.. (2020). Identification and Mechanistic Characterization of a Peptide Inhibitor of Glycogen Synthase Kinase (GSK3β) Derived from the Disrupted in Schizophrenia 1 (DISC1) Protein. ACS Chemical Neuroscience. 11(24). 4128–4138. 5 indexed citations

13.

Silva, M. Catarina, Sharon Tentarelli, Ian Gurrell, et al.. (2020). Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons. Nature Communications. 11(1). 3258–3258. 102 indexed citations

14.

Silva, M. Catarina, Fleur M. Ferguson, Quan-Ying Cai, et al.. (2019). Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. eLife. 8. 203 indexed citations

15.

Li, Lingling, Ana M. García, Wen‐Ning Zhao, et al.. (2019). Benzothiazole-Based LRRK2 Inhibitors as Wnt Enhancers and Promoters of Oligodendrocytic Fate. Journal of Medicinal Chemistry. 63(5). 2638–2655. 17 indexed citations

16.

Lin, Xudong, Xin Duan, Claire S. Jacobs, et al.. (2018). High-throughput brain activity mapping and machine learning as a foundation for systems neuropharmacology. Nature Communications. 9(1). 5142–5142. 39 indexed citations

17.

Zhao, Wen‐Ning, Balaram Ghosh, Marshall Tyler, et al.. (2018). Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory. ACS Chemical Neuroscience. 9(9). 2262–2273. 19 indexed citations

18.

Campbell, Arthur J., Wen‐Ning Zhao, Frederick A. Schroeder, et al.. (2017). HDAC6 Brain Mapping with [¹⁸F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination. ACS Central Science. 3(9). 1006–1014. 61 indexed citations

19.

Seo, Jinsoo, Oleg Kritskiy, L. Ashley Watson, et al.. (2017). Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia. Journal of Neuroscience. 37(41). 9917–9924. 120 indexed citations

20.

Forman, Joshua J, Paul A. Clemons, Stuart L. Schreiber, & Stephen J. Haggarty. (2005). SpectralNET – an application for spectral graph analysis and visualization. BMC Bioinformatics. 6(1). 260–260. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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