Heather L. Osswald

1.6k total citations · 1 hit paper
20 papers, 1.1k citations indexed

About

Heather L. Osswald is a scholar working on Infectious Diseases, Organic Chemistry and Virology. According to data from OpenAlex, Heather L. Osswald has authored 20 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Infectious Diseases, 10 papers in Organic Chemistry and 9 papers in Virology. Recurrent topics in Heather L. Osswald's work include HIV/AIDS drug development and treatment (12 papers), HIV Research and Treatment (9 papers) and Click Chemistry and Applications (7 papers). Heather L. Osswald is often cited by papers focused on HIV/AIDS drug development and treatment (12 papers), HIV Research and Treatment (9 papers) and Click Chemistry and Applications (7 papers). Heather L. Osswald collaborates with scholars based in United States, Japan and United Kingdom. Heather L. Osswald's co-authors include Arun K. Ghosh, Prasanth R. Nyalapatla, Andrew D. Mesecar, Hiroaki Mitsuya, Sarah E. St. John, Johnson Agniswamy, Irene T. Weber, Masayuki Amano, Manabu Aoki and Sakshi Tomar and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Chemical Society Reviews and Journal of Biological Chemistry.

In The Last Decade

Heather L. Osswald

20 papers receiving 1.1k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS

2016 312 citations Arun K. Ghosh, Heather L. Osswald et al. Journal of Medicinal Chemistry profile →

Peers

Countries citing papers authored by Heather L. Osswald

Since Specialization

Citations

This map shows the geographic impact of Heather L. Osswald's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Heather L. Osswald with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Heather L. Osswald more than expected).

Fields of papers citing papers by Heather L. Osswald

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Heather L. Osswald. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Heather L. Osswald. The network helps show where Heather L. Osswald may publish in the future.

Co-authorship network of co-authors of Heather L. Osswald

This figure shows the co-authorship network connecting the top 25 collaborators of Heather L. Osswald. A scholar is included among the top collaborators of Heather L. Osswald based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Heather L. Osswald. Heather L. Osswald is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies 2020 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, (unknown), Heather L. Osswald, Masayuki Amano, Manabu Aoki, Johnson Agniswamy, Yuan‐Fang Wang, Irene T. Weber, Hiroaki Mitsuya	22
2	A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant 2020 ·UNC Libraries ·Mark T. Heise, Eric Donaldson, Arun K. Ghosh, Robin Gopal, Trevor Scobey, Maria Zambon, Boyd L. Yount, Jeremy Huynh, Ralph S. Baric, Mark R. Denison, Michelle M. Becker, Heather L. Osswald, Rachel L. Graham, Lisa E. Gralinski, Andrew D. Mesecar, Sakshi Tomar, Vineet D. Menachery, Alan C. Whitmore, Sudhakar Agnihothram	2
3	Modular, stereocontrolled C _β –H/C _α –C activation of alkyl carboxylic acids 2019 ·Proceedings of the National Academy of Sciences ·Ming Shang, Karla Santos Feu, Julien C. Vantourout, Lisa M. Barton, Heather L. Osswald, Nobutaka Kato, Kerstin Gagaring, Case W. McNamara, Gang Chen, Liang Hu, Shengyang Ni, (unknown), Miao Chen, Rohan R. Merchant, Tian Qin, Stuart L. Schreiber, Bruno Melillo, Jin‐Quan Yu, Phil S. Baran	42
4	Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands 2018 ·European Journal of Medicinal Chemistry ·Arun K. Ghosh, (unknown), (unknown), (unknown), Heather L. Osswald, Johnson Agniswamy, Yuan‐Fang Wang, Shin-ichiro Hattori, Irene T. Weber, Hiroaki Mitsuya	5
5	Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure–Activity Studies, Biological and X-ray Structural Analysis 2018 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, Prasanth R. Nyalapatla, (unknown), Kalapala Venkateswara Rao, Margherita Brindisi, Heather L. Osswald, Masayuki Amano, Manabu Aoki, Johnson Agniswamy, Yuan‐Fang Wang, Irene T. Weber, Hiroaki Mitsuya	32
6	Design of Highly Potent, Dual‐Acting and Central‐Nervous‐System‐Penetrating HIV‐1 Protease Inhibitors with Excellent Potency against Multidrug‐Resistant HIV‐1 Variants 2018 ·ChemMedChem ·Arun K. Ghosh, Kalapala Venkateswara Rao, Prasanth R. Nyalapatla, (unknown), Margherita Brindisi, Heather L. Osswald, Bhavanam Sekhara Reddy, Johnson Agniswamy, Yuan‐Fang Wang, Manabu Aoki, Shin‐ichiro Hattori, Irene T. Weber, Hiroaki Mitsuya	33
7	Simultaneous Online Monitoring of Multiple Reactions Using a Miniature Mass Spectrometer 2017 ·Analytical Chemistry ·Christopher J. Pulliam, Ryan M. Bain, Heather L. Osswald, Dalton T. Snyder, Patrick W. Fedick, (unknown), Tawnya G. Flick, R. Graham Cooks	14
8	Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants 2017 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, Kalapala Venkateswara Rao, Prasanth R. Nyalapatla, Heather L. Osswald, (unknown), Manabu Aoki, Hironori Hayashi, Johnson Agniswamy, Yuan-Fang Wang, Haydar Bulut, Debananda Das, Irene T. Weber, Hiroaki Mitsuya	62
9	Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS breakdown → 2016 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, Heather L. Osswald, (unknown)	312
10	Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV-1 Protease Inhibitors: Design, Synthesis, Protein X-ray Structural Studies, and Biological Evaluation 2016 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, Heather L. Osswald, (unknown), Johnson Agniswamy, Yuan-Fang Wang, Hironori Hayashi, Manabu Aoki, Irene T. Weber, Hiroaki Mitsuya	12
11	Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro) 2015 ·Journal of Biological Chemistry ·Sakshi Tomar, Melanie L. Johnston, Sarah E. St. John, Heather L. Osswald, Prasanth R. Nyalapatla, Lake N. Paul, Arun K. Ghosh, Mark R. Denison, Andrew D. Mesecar	111
12	X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design 2015 ·Bioorganic & Medicinal Chemistry Letters ·Sarah E. St. John, (unknown), Prasanth R. Nyalapatla, Heather L. Osswald, Arun K. Ghosh, Andrew D. Mesecar	16
13	Enantioselective synthesis of dioxatriquinane structural motifs for HIV-1 protease inhibitors using a cascade radical cyclization 2015 ·Tetrahedron Letters ·Arun K. Ghosh, Chunxiao Xu, Heather L. Osswald	7
14	Design of HIV-1 Protease Inhibitors with Amino-bis-tetrahydrofuran Derivatives as P2-Ligands to Enhance Backbone-Binding Interactions: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Studies 2015 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, (unknown), Heather L. Osswald, (unknown), (unknown), Shujing Chen, Johnson Agniswamy, Yuan-Fang Wang, Hironori Hayashi, Manabu Aoki, Irene T. Weber, Hiroaki Mitsuya	9
15	Structure-Based Design of Potent HIV-1 Protease Inhibitors with Modified P1-Biphenyl Ligands: Synthesis, Biological Evaluation, and Enzyme–Inhibitor X-ray Structural Studies 2015 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, Xufen Yu, Heather L. Osswald, Johnson Agniswamy, Yuan-Fang Wang, Masayuki Amano, Irene T. Weber, Hiroaki Mitsuya	23
16	BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's disease 2014 ·Chemical Society Reviews ·Arun K. Ghosh, Heather L. Osswald	274
17	A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant 2014 ·mBio ·Sudhakar Agnihothram, Boyd L. Yount, Eric Donaldson, Jeremy Huynh, Vineet D. Menachery, Lisa E. Gralinski, Rachel L. Graham, Michelle M. Becker, Sakshi Tomar, Trevor Scobey, Heather L. Osswald, Alan C. Whitmore, Robin Gopal, Arun K. Ghosh, Andrew D. Mesecar, Maria Zambon, Mark T. Heise, Mark R. Denison, Ralph S. Baric	46
18	Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1–P2 ligands 2014 ·Organic & Biomolecular Chemistry ·Arun K. Ghosh, Gary E. Schiltz, L.N. Rusere, Heather L. Osswald, D. Eric Walters, Masayuki Amano, Hiroaki Mitsuya	18
19	Coronaviruses Resistant to a 3C-Like Protease Inhibitor Are Attenuated for Replication and Pathogenesis, Revealing a Low Genetic Barrier but High Fitness Cost of Resistance 2014 ·Journal of Virology ·Xufang Deng, Sarah E. St. John, Heather L. Osswald, Amornrat O’Brien, Bridget S. Banach, Katrina Sleeman, Arun K. Ghosh, Andrew D. Mesecar, Susan C. Baker	68
20	Highly Potent HIV-1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein–Ligand X-ray Studies 2013 ·Journal of Medicinal Chemistry ·Arun K. Ghosh, (unknown), (unknown), Prasanth R. Nyalapatla, Heather L. Osswald, Johnson Agniswamy, Yuan-Fang Wang, Masayuki Amano, Irene T. Weber, Hiroaki Mitsuya	40

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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