Kenneth H. Pearce

4.8k citations

71 papers · 3.3k indexed · 2 hit papers · h-index 27

Molecular Biology top 5%
Genetics top 2%
Endocrinology, Diabetes and Metabolism top 2%
Oncology top 10%
Endocrine and Autonomic Systems top 2%

Co-authors: Derek J. Parks John T. Moore Randy K. Bledsoe Eugene L. Stewart Timothy M. Willson Millard H. Lambert Thomas B. Stanley C.J. Apolito
Topics: Epigenetics and DNA Methylation (10 papers)Estrogen and related hormone effects (10 papers)Protein Degradation and Inhibitors (8 papers)
Cited by: Endocrine and Autonomic Systems Aging Genetics
Journals: Science Cell Journal of the American Chemical Society
Partner nations: United States Canada United Kingdom

In The Last Decade

Kenneth H. Pearce

68 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

2002 652 citations Randy K. Bledsoe, Valerie G. Montana et al. Cell profile →
Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

2007 572 citations Lei Yin, Nan Wu et al. Science profile →

Peers

Countries citing papers authored by Kenneth H. Pearce

Since Specialization

Citations

This map shows the geographic impact of Kenneth H. Pearce's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth H. Pearce with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth H. Pearce more than expected).

Fields of papers citing papers by Kenneth H. Pearce

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth H. Pearce. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth H. Pearce. The network helps show where Kenneth H. Pearce may publish in the future.

Co-authorship network of co-authors of Kenneth H. Pearce

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth H. Pearce. A scholar is included among the top collaborators of Kenneth H. Pearce based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth H. Pearce. Kenneth H. Pearce is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Development of Next Generation Cell-Permeable Peptide Inhibitors for the Oncological Target MAGE-A4 2025 ·Journal of Medicinal Chemistry ·(unknown),(unknown),(unknown),(unknown),Jacqueline L. Norris‐Drouin,(unknown),Konstantin Popov,Cyrus Vaziri,Albert A. Bowers,Kenneth H. Pearce	0
2	A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics 2025 ·Nature Microbiology ·Kuan‐Yi Lu,(unknown),(unknown),Rui Sun,(unknown),B Morris,Nikki J. Wagner,(unknown),(unknown),Sarah E. Rowe,Xiaodong Wang,Vance G. Fowler,Qingyun Liu,Sophie Hélaine,Kenneth H. Pearce,Brian P. Conlon	2
3	A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-γ2 to treat Alzheimer's disease 2025 ·Journal of Biological Chemistry ·(unknown),Nicole Hajicek,Andy P. Tsai,Prakash Acharya,(unknown),(unknown),Tony Wyss‐Coray,Kenneth H. Pearce,John Sondek,Qisheng Zhang	0
4	A multi-kinase inhibitor screen identifies inhibitors preserving stem-cell-like chimeric antigen receptor T cells 2025 ·Nature Immunology ·Feifei Song,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Thomas S.K. Gilbert,Lee M. Graves,Laura E. Herring,Barbara Savoldo,Xingcong Ma,Mark G. Woodcock,J. Justin Milner,Anastasia Ivanova,Kenneth H. Pearce,Yang Xu,Gianpietro Dotti	5
5	Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity 2024 ·Journal of Medicinal Chemistry ·(unknown),(unknown),Mohammad Anwar Hossain,Peter J. Brown,Meganathan Nandakumar,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Sumera Perveen,Kenneth H. Pearce,Konstantin Popov,Nathaniel J. Moorman,Mark T. Heise,Timothy M. Willson	5
6	Discovery of FERM domain protein–protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer’s disease 2023 ·Journal of Biological Chemistry ·Yuhong Du,W.J. Bradshaw,(unknown),(unknown),Kun Qian,(unknown),(unknown),(unknown),Andrei A. Ivanov,Stephen V. Frye,O. Gileadi,Paul E. Brennan,Allan I. Levey,Alison D. Axtman,Kenneth H. Pearce,Haian Fu,V.L. Katis	8
7	Fused Tetrahydroquinolines Are Interfering with Your Assay 2023 ·Journal of Medicinal Chemistry ·(unknown),(unknown),Yuhong Du,V.L. Katis,(unknown),(unknown),Stephen V. Frye,Kenneth H. Pearce,Haian Fu,Timothy M. Willson,David H. Drewry,Alison D. Axtman	4
8	Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions 2022 ·Journal of Medicinal Chemistry ·Yubai Zhou,(unknown),(unknown),Molee Chakraborty,Chunfang Gu,Guangning Zong,Michael A. Stashko,Kenneth H. Pearce,Stephen B. Shears,Anutosh Chakraborty,Huanchen Wang,Xiaodong Wang	21
9	Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library 2022 ·SLAS DISCOVERY ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Fengling Li,Jacqueline L. Norris‐Drouin,(unknown),(unknown),Masoud Vedadi,Stephen V. Frye,Lindsey I. James,Kenneth H. Pearce	6
10	BacMam production and crystal structure of nonglycosylated apo human furin at 1.89 Å resolution 2019 ·Acta Crystallographica Section F Structural Biology Communications ·Kenneth H. Pearce,Laurie K. Overton,Robert T. Gampe,(unknown),J. David Taylor,David D. McKee,Nino Campobasso,Robert T. Nolte,Robert A. Reid	12
11	A General TR-FRET Assay Platform for High-Throughput Screening and Characterizing Inhibitors of Methyl-Lysine Reader Proteins 2019 ·SLAS DISCOVERY ·(unknown),(unknown),Jacqueline L. Norris‐Drouin,Stephanie H. Cholensky,Lindsey I. James,Stephen V. Frye,Kenneth H. Pearce	23
12	Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7 2019 ·Cell chemical biology ·Kelsey N. Lamb,(unknown),(unknown),(unknown),Huitao Fan,Jacob I. Stuckey,Jacqueline L. Norris,Stephanie H. Cholensky,Dongxu Li,Jingkui Wang,Cari A. Sagum,Benjamin Z. Stanton,Mark T. Bedford,Kenneth H. Pearce,Terry Kenakin,Dmitri Kireev,Gang Greg Wang,Lindsey I. James,Oliver Bell,Stephen V. Frye	42
13	Use of Protein Kinase–Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors 2018 ·SLAS DISCOVERY ·(unknown),Michael A. Stashko,Huanchen Wang,(unknown),Vikas Tyagi,Bing Li,Xiaodong Wang,Dmitri Kireev,Henning J. Jessen,Stephen V. Frye,Stephen B. Shears,Kenneth H. Pearce	18
14	Expression, purification, and characterization of multiple, multifunctional human glucocorticoid receptor proteins 2008 ·Protein Expression and Purification ·Catherine A. Simmons,Randy K. Bledsoe,Nicolas Guex,Kenneth H. Pearce	6
15	Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathwaysbreakdown → 2007 ·Science ·Lei Yin,Nan Wu,Joshua C. Curtin,Mohammed Qatanani,(unknown),Robert A. Reid,(unknown),Derek J. Parks,Kenneth H. Pearce,G. Bruce Wisely,Mitchell A. Lazar	572
16	Co-crystal structure guided array synthesis of PPARγ inverse agonists 2007 ·Bioorganic & Medicinal Chemistry Letters ·Ryan P. Trump,(unknown),Barry G. Shearer,Millard H. Lambert,Robert T. Nolte,Timothy M. Willson,Richard G. Buckholz,Sumin Zhao,Lisa M. Leesnitzer,Marie A. Iannone,Kenneth H. Pearce,Andrew N. Billin,William J. Hoekstra	15
17	The Nuclear Receptor Superfamily and Drug Discovery 2006 ·ChemMedChem ·John T. Moore,Jon L. Collins,Kenneth H. Pearce	116
18	Recent applications of protein crystallography and structure-guided drug design 2005 ·Current Opinion in Chemical Biology ·Shawn P. Williams,Lee F. Kuyper,Kenneth H. Pearce	30
19	Structure and Function of the Glucocorticoid Receptor Ligand Binding Domain 2004 ·Vitamins and hormones ·Randy K. Bledsoe,Eugene L. Stewart,Kenneth H. Pearce	48
20	Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognitionbreakdown → 2002 ·Cell ·Randy K. Bledsoe,Valerie G. Montana,Thomas B. Stanley,Chris J. Delves,C.J. Apolito,David D. McKee,Thomas G. Consler,Derek J. Parks,Eugene L. Stewart,Timothy M. Willson,Millard H. Lambert,John T. Moore,Kenneth H. Pearce,H. Eric Xu	652

About Kenneth H. Pearce

Kenneth H. Pearce is a scholar working on Molecular Biology, Hematology and Computational Theory and Mathematics, having authored 71 papers that have together received 3.3k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (10 papers), Estrogen and related hormone effects (10 papers) and Protein Degradation and Inhibitors (8 papers). The work is most often cited by research in Endocrine and Autonomic Systems (304 citations), Aging (74 citations) and Genetics (946 citations). Kenneth H. Pearce has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Derek J. Parks, John T. Moore, Randy K. Bledsoe, Eugene L. Stewart, Timothy M. Willson, Millard H. Lambert, Thomas B. Stanley, C.J. Apolito, Thomas G. Consler and Robert A. Reid. Their work appears in journals such as Science, Cell and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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