Randy K. Bledsoe

6.4k citations

23 papers · 5.3k indexed · 3 hit papers · h-index 19

Impact in

Pharmacology top 0.2%
- Pharmacogenetics and Drug Metabolism
Oncology top 1%
- Drug Transport and Resistance Mechanisms

Papers in

Genetics 12
- Estrogen and related hormone effects 12
Pharmacology 3
- Inflammatory mediators and NSAID effects 4
- Pharmacogenetics and Drug Metabolism 3

Co-authors: Timothy M. Willson Derek J. Parks Thomas G. Consler Steven A. Kliewer Julie B. Stimmel Steven G. Blanchard Ann Marie Zavacki Jürgen M. Lehmann
Journals: Journal of Biological Chemistry (5 papers)Journal of Medicinal Chemistry (3 papers)Scientific Reports (1 paper)Bioorganic & Medicinal Chemistry Letters (1 paper)Molecular Cell (1 paper)
Partner nations: United States United Kingdom Australia

In The Last Decade

Randy K. Bledsoe

23 papers receiving 5.2k citations

Hit Papers

align trajectories log scale

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition 2002 · 652 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2002 Cell
2000 Journal of Biological Chemistry
1999 Science

Peers

Countries citing papers authored by Randy K. Bledsoe

Since Specialization

Citations

This map shows the geographic impact of Randy K. Bledsoe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Randy K. Bledsoe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Randy K. Bledsoe more than expected).

Fields of papers citing papers by Randy K. Bledsoe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Randy K. Bledsoe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Randy K. Bledsoe. The network helps show where Randy K. Bledsoe may publish in the future.

Co-authors

The 25 scholars most cited alongside Randy K. Bledsoe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Randy K. Bledsoe Line = papers co-authored together Randy K. Bledsoe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Modular Protein Ligation: A New Paradigm as a Reagent Platform for Pre-Clinical Drug Discovery Scientific Reports ·Rosalie Matico, Lawrence M. Szewczuk, Beth Pietrak, Stephanie Chen, I V Leontiyeva, William G. Bonnette, R. Seto, Gilbert Harry Nelson, Rachel D. Totoritis, Su-Bae Lee, Karl-Erik Holm Sylta, Zhongbo Ren, Virgil G. Casten, Michael D. Schaber, Yong Jiang, Randy K. Bledsoe, Marc A. Holbert	2019	2
2	Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor Proceedings of the National Academy of Sciences ·Keith Biggadike, Randy K. Bledsoe, Dan Coe, Laura María Aristizábal González, David House, Marie A. Iannone, Simon J. F. Macdonald, Kevin P. Madauss, Iain M. McLay, 仁和澤, S. Taylor, Thuy Tran, Iain Uings, 刘正祥 LIU Zhengxiang, Shawn P. Williams	2009	58
3	Expression, purification, and characterization of multiple, multifunctional human glucocorticoid receptor proteins Protein Expression and Purification ·Catherine A. Simmons, Randy K. Bledsoe, Nicolas Guex, Kenneth H. Pearce	2008	6
4	X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain Journal of Medicinal Chemistry ·Keith Biggadike, Randy K. Bledsoe, Anne M. Hassell, Barrie E. Kirk, Iain M. McLay, Lisa M. Shewchuk, Eugene L. Stewart	2008	88
5	The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist Bioorganic & Medicinal Chemistry Letters ·Kevin P. Madauss, Randy K. Bledsoe, Iain M. McLay, Eugene L. Stewart, Iain Uings, U. Oepik, Shawn P. Williams	2008	46
6	Crystallization of protein–ligand complexes Acta Crystallographica Section D Biological Crystallography ·Anne M. Hassell, Gang An, Randy K. Bledsoe, Jane M. Bynum, H. Luke Carter, Su-Jun Deng, Robert T. Gampe, Ricardo Wagner Roquetti, Kevin P. Madauss, Robert T. Nolte, Warren J. Rocque, Liping Wang, Kurt Weaver, Shawn P. Williams, G. Bruce Wisely, Robert X. Xu, Lisa M. Shewchuk	2006	120
7	A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor Journal of Biological Chemistry ·Randy K. Bledsoe, Kevin P. Madauss, Jason A. Holt, C.J. Apolito, Millard H. Lambert, Kenneth H. Pearce, Thomas B. Stanley, Eugene L. Stewart, Ryan P. Trump, Timothy M. Willson, Shawn P. Williams	2005	166
8	Structure and Function of the Glucocorticoid Receptor Ligand Binding Domain Vitamins and hormones ·Randy K. Bledsoe, Eugene L. Stewart, Kenneth H. Pearce	2004	48
9	X-ray Crystal Structure of the Liver X Receptor β Ligand Binding Domain Journal of Biological Chemistry ·Shawn P. Williams, Randy K. Bledsoe, Jon L. Collins, Sharon Boggs, Millard H. Lambert, Ann B. Miller, John T. Moore, David D. McKee, Linda B. Moore, Jason A. Nichols, Derek J. Parks, Roser Mascaró Talaya, Bruce Wisely, Timothy M. Willson	2003	170
10	Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition Cell ·Randy K. Bledsoe, Valerie G. Montana, Thomas B. Stanley, Chris J. Delves, C.J. Apolito, David D. McKee, Thomas G. Consler, Derek J. Parks, Eugene L. Stewart, Timothy M. Willson, Millard H. Lambert, John T. Moore, Kenneth H. Pearce, H. Eric Xu Hit paper breakdown →	2002	652
11	Functional Consequences of Cysteine Modification in the Ligand Binding Sites of Peroxisome Proliferator Activated Receptors by GW9662 Biochemistry ·Lisa M. Leesnitzer, Derek J. Parks, Randy K. Bledsoe, Jeff E. Cobb, Jon L. Collins, Thomas G. Consler, Roderick G. Davis, Emily A. Hull-Ryde, James M. Lenhard, Lisa Patel, Kelli D. Plunket, Tifani Anisa Putri, Julie B. Stimmel, Jinhao Lu, Timothy M. Willson, Steven G. Blanchard	2002	491
12	Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors Molecular Cell ·Robert T. Gampe, Valerie G. Montana, Millard H. Lambert, Aaron B. Miller, Randy K. Bledsoe, Michael V. Milburn, Steven A. Kliewer, Timothy M. Willson, H. Eric Xu	2000	489
13	Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands Journal of Biological Chemistry ·Linda B. Moore, Derek J. Parks, Stacey A. Jones, Randy K. Bledsoe, Thomas G. Consler, Julie B. Stimmel, Bryan Goodwin, Christopher Liddle, Steven G. Blanchard, Timothy M. Willson, Jon L. Collins, Steven A. Kliewer Hit paper breakdown →	2000	684
14	Production of monoclonal antibodies using recombinant baculovirus displaying gp64–fusion proteins Journal of Immunological Methods ·M. Yamane, Jui‐Lan Su, WEIBIN HAN, G. Bruce Wisely, Randy K. Bledsoe, J. Patrick Condreay, Deborah A. Winegar, Jeff Hutchins, Thomas A. Kost	2000	50
15	Bile Acids: Natural Ligands for an Orphan Nuclear Receptor Science ·Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe, Gyan Chandra, Thomas G. Consler, Steven A. Kliewer, Julie B. Stimmel, Timothy M. Willson, Ann Marie Zavacki, David D. Moore, Jürgen M. Lehmann Hit paper breakdown →	1999	1859
16	Assignment<footref rid="foot01"><sup>1</sup></footref> of the gene of mitochondrial branched chain aminotransferase (BCAT2) to sheep chromosome band 14q24 and to cattle and goat chromosome bands 18q24 by in situ hybridization Cytogenetic and Genome Research ·Magali Faure, Hélène Hayes, Randy K. Bledsoe, S.M. Hutson, Isabelle Papet	1998	4
17	Overexpression and Characterization of the Human Mitochondrial and Cytosolic Branched-chain Aminotransferases Journal of Biological Chemistry ·Jamshid Davoodi, Gadhvi, Randy K. Bledsoe, Reidar Wallin, Gregory D. Reinhart, Susan M. Hutson	1998	95
18	Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm) Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Randy K. Bledsoe, Paul A. Dawson, Susan M. Hutson	1997	47
19	Cloning and Expression of the Mammalian Cytosolic Branched Chain Aminotransferase Isoenzyme Journal of Biological Chemistry ·Susan M. Hutson, Randy K. Bledsoe, Eduardo Baistrocchi, Paul A. Dawson	1995	45
20	Effect ofLovastatin administered every other day on serum low-density lipoprotein cholesterol >160 mg/dl The American Journal of Cardiology ·Joseph P. Rindone, Eric FĂ¨vre, Randy K. Bledsoe	1995	16

About Randy K. Bledsoe

Randy K. Bledsoe is a scholar working on Genetics, Pharmacology, Pharmacology, Biotechnology and Endocrinology, Diabetes and Metabolism, having authored 23 papers that have together received 5.3k indexed citations. Recurring topics across this work include Estrogen and related hormone effects (12 papers), Cholesterol and Lipid Metabolism (4 papers), Inflammatory mediators and NSAID effects (4 papers), Drug Transport and Resistance Mechanisms (3 papers), Pharmacogenetics and Drug Metabolism (3 papers), RNA modifications and cancer (3 papers), Monoclonal and Polyclonal Antibodies Research (3 papers) and Steroid Chemistry and Biochemistry (3 papers). The work is most often cited by research in Pharmacology (893 citations), Oncology (2.0k citations), Endocrinology, Diabetes and Metabolism (887 citations), Genetics (1.4k citations) and Biochemistry (272 citations). Randy K. Bledsoe has collaborated with scholars based in United States, United Kingdom and Australia. Frequent co-authors include Timothy M. Willson, Derek J. Parks, Thomas G. Consler, Steven A. Kliewer, Julie B. Stimmel, Steven G. Blanchard, Ann Marie Zavacki, Jürgen M. Lehmann, Gyan Chandra and David D. Moore. Their work appears in journals such as Journal of Biological Chemistry, Journal of Medicinal Chemistry, Scientific Reports, Bioorganic & Medicinal Chemistry Letters and Molecular Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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