Barry G. Shearer

2.2k citations

31 papers · 1.6k indexed · 1 hit paper · h-index 18

Biochemistry top 5%
- Eicosanoids and Hypertension Pharmacology 5
Molecular Biology top 10%
- Peroxisome Proliferator-Activated Receptors 11
- Chemical Synthesis and Analysis 4
Physiology top 5%
- Adipose Tissue and Metabolism 6
- Nitric Oxide and Endothelin Effects 4
Physiology top 10%
- Adipose Tissue and Metabolism 6
- Nitric Oxide and Endothelin Effects 4
Genetics top 10%
Organic Chemistry
- Synthetic Organic Chemistry Methods 5
- Asymmetric Synthesis and Catalysis 4
Oncology
- Drug Transport and Resistance Mechanisms 4

Co-authors: Timothy M. Willson John T. Moore William J. Hoekstra Thomas B. Stanley Millard H. Lambert James A. Marshall Robert T. Nolte Steven A. Kliewer
Cited by: Biochemistry Molecular Biology Physiology
Journals: Journal of Medicinal Chemistry (7 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)The Journal of Organic Chemistry (4 papers)
Partner nations: United States United Kingdom Netherlands

In The Last Decade

Barry G. Shearer

30 papers receiving 1.6k citations

Hit Papers

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Peers

Countries citing papers authored by Barry G. Shearer

Since Specialization

Citations

This map shows the geographic impact of Barry G. Shearer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Barry G. Shearer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Barry G. Shearer more than expected).

Fields of papers citing papers by Barry G. Shearer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Barry G. Shearer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Barry G. Shearer. The network helps show where Barry G. Shearer may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Barry G. Shearer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Barry G. Shearer Line = papers co-authored together Barry G. Shearer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	2,4-Diamino-8-quinazoline carboxamides as novel, potent inhibitors of the NAD hydrolyzing enzyme CD38: Exploration of the 2-position structure-activity relationships Bioorganic & Medicinal Chemistry ·David N. Deaton,Curt D. Haffner,Brad R. Henke,Michael R. Jeune,Barry G. Shearer,Eugene L. Stewart,J. Darren Stuart,John C. Ulrich	2018	12
2	Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist Bioorganic & Medicinal Chemistry Letters ·MA Zhanhon,Canfeng Dou,Paul B. Chapman,Naiara C. Silva,Gerard M.P. Giblin,Mark P. Healy,Millard H. Lambert,Lisa M. Leesnitzer,Catrin Swantje Müller,Raymond V. Merrihew,A. Richard Rutter,Rosemary Sasse,Barry G. Shearer,Timothy M. Wilson,Robert X. Xu,David Virley	2011	20
3	Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy Bioorganic & Medicinal Chemistry Letters ·Karen A. Evans,Barry G. Shearer,David D. Wisnoski,余佳泓,Steven M. Sparks,Daniel D. Sternbach,Deborah A. Winegar,Andrew N. Billin,Sabato Mignano,James M. Way,Andrea H. Epperly,Lisa M. Leesnitzer,Raymond V. Merrihew,Robert X. Xu,Millard H. Lambert,Jian Jin	2011	8
4	Discovery of a novel class of PPARδ partial agonists Bioorganic & Medicinal Chemistry Letters ·Barry G. Shearer,Hari S. Patel,Andrew N. Billin,James M. Way,Deborah A. Winegar,Millard H. Lambert,Robert X. Xu,Lisa M. Leesnitzer,Raymond V. Merrihew,Stéphane Huet,Timothy M. Willson	2008	19
5	Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor β/δ (NR1C2) Antagonist Molecular Endocrinology ·Barry G. Shearer,David J. Steger,James M. Way,Thomas B. Stanley,David C. Lobe,Didier Grillot,Marie A. Iannone,Mitchell A. Lazar,Timothy M. Willson,Andrew N. Billin	2007	114
6	Co-crystal structure guided array synthesis of PPARγ inverse agonists Bioorganic & Medicinal Chemistry Letters ·Ryan P. Trump,Sait Alkan,Barry G. Shearer,Millard H. Lambert,Robert T. Nolte,Timothy M. Willson,Richard G. Buckholz,Sumin Zhao,Lisa M. Leesnitzer,Marie A. Iannone,Kenneth H. Pearce,Andrew N. Billin,William J. Hoekstra	2007	15
7	Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids Bioorganic & Medicinal Chemistry Letters ·Barry G. Shearer,Esther Y. Chao,David Uehling,David N. Deaton,Conrad L. Cowan,Bryan W. Sherman,J.R Vega Avila,Studiengruppe Kolposkopie,Kathleen K. Brown,Kimberly K. Adkison,Frank Lee	2007	15
8	Recent Advances in Peroxisome Proliferator- Activated Receptor Science Barry G. Shearer,William J. Hoekstra	2005	10
9	Recent Advances in Peroxisome Proliferator-Activated Receptor Science Current Medicinal Chemistry ·Barry G. Shearer,William J. Hoekstra	2003	86
10	Synthesis and Identification of a Novel 6,5,6-Tricyclic Lactam Heterocycles ·Joel P. Cooper,Jeff E. Cobb,Barry G. Shearer,Douglas J. Minick,Craig Andrew Hunn	2003	0
11	Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARαbreakdown → Nature ·H. Eric Xu,Thomas B. Stanley,Valerie G. Montana,Millard H. Lambert,Barry G. Shearer,Jeffery E. Cobb,David D. McKee,Cristin M. Galardi,Kelli D. Plunket,Robert T. Nolte,Derek J. Parks,John T. Moore,Steven A. Kliewer,Timothy M. Willson,Julie B. Stimmel	2002	521
12	"Peroxisome Proliferator-Activated Receptors (PPARs): Choreographers of Metabolic Gene Transcription" Barry G. Shearer,William J. Hoekstra	2002	5
13	Hepatocyte Nuclear Factor 4 Is a Transcription Factor that Constitutively Binds Fatty Acids Structure ·G. Bruce Wisely,Ann B. Miller,Roderick G. Davis,吉村吾志夫,Robert L. Johnson,Benjamin E. Fountain,Andrea M. Sefler,Barry G. Shearer,John T. Moore,Aaron B. Miller,Timothy M. Willson,Shawn P. Williams	2002	246
14	S-2-Naphthylmethyl thioacetimidate hydrobromide: A new odorless reagent for the mild synthesis of substituted acetamidines Tetrahedron Letters ·Barry G. Shearer,Jeffrey A. Oplinger,Shuliang Lee	1997	33
15	NPC 15437 interacts with the C1 domain of protein kinase C An analysis using mutant PKC constructs FEBS Letters ·James P. Sullivan,Jane R. Connor,Carol W. Tiffany,Barry G. Shearer,Ronald M. Burch	1991	22
16	Substituted 2-(aminomethyl)piperidines: a novel class of selective protein kinase C inhibitors Journal of Medicinal Chemistry ·Barry G. Shearer,James P. Sullivan,Mit suhiro Fujino,Rose Mathew,Cleide Lugarini de Andrade,Jane R. Connor,Raymond J. Patch,Ronald M. Burch	1991	9
17	Synthesis of (D)- and (L)-forms of differentially protected 2-piperidinemethanamine Tetrahedron Letters ·John Perumattam,Barry G. Shearer,辰己角,Rose Mathew	1991	16
18	Stereoselective synthesis of a nonracemic hydronaphthalene subunit of kijanolide The Journal of Organic Chemistry ·James A. Marshall,James M. Salovich,Barry G. Shearer	1990	17
19	Thermal and catalyzed intramolecular Diels-Alder cyclizations of 2,8,10-undecatrienals The Journal of Organic Chemistry ·James A. Marshall,Barry G. Shearer,S. Pruna	1987	48
20	Conjugate addition of organocuprates to trans-4a,5,6,7,8,8a-hexahydronaphthalene-1-carboxaldehydes. Synthesis of a chlorothricin degradation product The Journal of Organic Chemistry ·James A. Marshall,James E. Audia,Barry G. Shearer	1986	17

About Barry G. Shearer

Barry G. Shearer is a scholar working on Biochemistry, Organic Chemistry and Physiology, having authored 31 papers that have together received 1.6k indexed citations. Recurring topics across this work include Peroxisome Proliferator-Activated Receptors (11 papers), Adipose Tissue and Metabolism (6 papers), Eicosanoids and Hypertension Pharmacology (5 papers), Synthetic Organic Chemistry Methods (5 papers), Chemical Synthesis and Analysis (4 papers), Nitric Oxide and Endothelin Effects (4 papers), Drug Transport and Resistance Mechanisms (4 papers) and Asymmetric Synthesis and Catalysis (4 papers). The work is most often cited by research in Biochemistry (171 citations), Molecular Biology (1.0k citations) and Physiology (64 citations). Barry G. Shearer has collaborated with scholars based in United States, United Kingdom and Netherlands. Frequent co-authors include Timothy M. Willson, John T. Moore, William J. Hoekstra, Thomas B. Stanley, Millard H. Lambert, James A. Marshall, Robert T. Nolte, Steven A. Kliewer, Valerie G. Montana and H. Eric Xu. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, The Journal of Organic Chemistry, Tetrahedron Letters and Bioorganic & Medicinal Chemistry.

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