H. Eric Xu

40.4k total citations · 12 hit papers
326 papers, 24.1k citations indexed

About

H. Eric Xu is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, H. Eric Xu has authored 326 papers receiving a total of 24.1k indexed citations (citations by other indexed papers that have themselves been cited), including 227 papers in Molecular Biology, 76 papers in Cellular and Molecular Neuroscience and 37 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in H. Eric Xu's work include Receptor Mechanisms and Signaling (96 papers), Neuropeptides and Animal Physiology (42 papers) and Estrogen and related hormone effects (25 papers). H. Eric Xu is often cited by papers focused on Receptor Mechanisms and Signaling (96 papers), Neuropeptides and Animal Physiology (42 papers) and Estrogen and related hormone effects (25 papers). H. Eric Xu collaborates with scholars based in China, United States and Singapore. H. Eric Xu's co-authors include Karsten Melcher, Yi Jiang, Steven A. Kliewer, Millard H. Lambert, X. Edward Zhou, Kelly Suino-Powell, Timothy M. Willson, Yan Yan, Valerie G. Montana and Ting-Hai Xu and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

H. Eric Xu

301 papers receiving 23.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Amyloid beta: structure, biology and structure-based therapeutic development

2017 1.4k citations Yi Jiang, Karsten Melcher et al. profile →
Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

1999 938 citations H. Eric Xu et al. Molecular Cell profile →
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

2001 876 citations H. Eric Xu et al. Proceedings of the National Academy of Sciences profile →
Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

2002 652 citations H. Eric Xu et al. profile →
Androgen receptor: structure, role in prostate cancer and drug discovery

2014 650 citations H. Eric Xu, Karsten Melcher et al. profile →
DWARF 53 acts as a repressor of strigolactone signalling in rice

2013 649 citations Wei Yi, Lihua Zhao et al. Nature profile →
Structural basis for molecular recognition of folic acid by folate receptors

2013 582 citations Jiyuan Ke, X. Edward Zhou et al. Nature profile →
Structural Features for Functional Selectivity at Serotonin Receptors

2013 543 citations Daniel Wacker, Chong Wang et al. Science profile →
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα

2002 521 citations H. Eric Xu et al. Nature profile →
FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis

2011 503 citations H. Eric Xu et al. Science profile →
Structural insights into the lipid and ligand regulation of serotonin receptors

2021 185 citations Peiyu Xu, Sijie Huang et al. Nature profile →
Structures of the entire human opioid receptor family

2023 106 citations Yue Wang, Youwen Zhuang et al. profile →

Peers

Countries citing papers authored by H. Eric Xu

Since Specialization

Citations

This map shows the geographic impact of H. Eric Xu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by H. Eric Xu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites H. Eric Xu more than expected).

Fields of papers citing papers by H. Eric Xu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by H. Eric Xu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by H. Eric Xu. The network helps show where H. Eric Xu may publish in the future.

Co-authorship network of co-authors of H. Eric Xu

This figure shows the co-authorship network connecting the top 25 collaborators of H. Eric Xu. A scholar is included among the top collaborators of H. Eric Xu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with H. Eric Xu. H. Eric Xu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition 2026 ·Gut ·(unknown), (unknown), (unknown), H. Eric Xu, (unknown), (unknown), (unknown), Mingming Xiao, (unknown), (unknown)	0
2	Using street view imagery and localized crowdsourcing survey to model perceived safety of the visual built environment by gender 2025 ·International Journal of Applied Earth Observation and Geoinformation ·Hanlin Zhou, Jue Wang, Kathi Wilson, Michael J. Widener, Dongrui Wu, H. Eric Xu	2
3	Structural insights into antagonist recognition by the vasopressin V2 receptor 2025 ·Nature Communications ·(unknown), Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, (unknown), Canrong Wu, (unknown), Yu-Ling Yin, Kai Wu, (unknown), Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H. Eric Xu, Dong Guo, Yi Jiang	0
4	Mechanically Interlocked Polyimide@Cyclodextrin All-Organic Dielectric with Enhanced High-Temperature Capacitive Energy Storage Performance 2025 ·ACS Applied Polymer Materials ·(unknown), Guilin Liu, (unknown), (unknown), (unknown), Lihe Guo, Hongfei Li, H. Eric Xu	0
5	Polysaccharides from Syzygium aromaticum binding to 3CLpro contain glycoproteins interacting with RdRp against SARS-CoV-2 2025 ·Carbohydrate Polymers ·Can Jin, Bo Feng, (unknown), Yuan Zhou, Tingting Guo, Yuxuan Liu, (unknown), (unknown), (unknown), (unknown), (unknown), Xuan Li, Xiaojuan Xu, H. Eric Xu, (unknown), (unknown), Yi Zang, Jia Li, Kan Ding	1
6	Exosomal microRNA biomarkers in Alzheimer’s disease: Systematic review and meta-analysis 2025 ·Clinica Chimica Acta ·Shiyu Liu, Min Zhao, Xin Yang, Yuan Liu, H. Eric Xu, Hai Yan, (unknown)	0
7	Cu‐Doped V‐Based MOF Derivative VO ₂ @Cu‐VMOF as a Cathodic Catalyst for Electro‐Fenton Degradation of Antibiotics 2024 ·Small ·(unknown), Yanping Hou, (unknown), (unknown), Shiming Zhang, Ting Liang, H. Eric Xu, Shuangfei Wang	2
8	OA04.05 SHR-A1921, A TROP-2 Targeted Antibody-Drug Conjugate (ADC), In Patients (pts) with Advanced Small-Cell Lung Cancer (SCLC) 2024 ·Journal of Thoracic Oncology ·Jing Wang, Lingxiang Wu, Xi Li, Na Xing, Shuang Zhang, Zhuolun Song, Lan Chen, (unknown), Chao Liu, Ye Li, H. Eric Xu, (unknown), Yufeng Wu, Zhenyang Lin, Zhenhai Zhang, Shuai Wang	5
9	Structural basis of psychedelic LSD recognition at dopamine D1 receptor 2024 ·Neuron ·Luyu Fan, Youwen Zhuang, Hongyu Wu, (unknown), (unknown), Yue Wang, (unknown), Shishan Wang, Zhangcheng Chen, Jianjun Cheng, H. Eric Xu, Sheng Wang	3
10	Structural features of arrestin-mediated GPCR signaling 2024 ·SHILAP Revista de lepidopterología ·Wenqin Xie, (unknown), Hongmin Cai, H. Eric Xu, Wanchao Yin	0
11	Recognition of methamphetamine and other amines by trace amine receptor TAAR1 2023 ·Nature ·(unknown), You Zheng, (unknown), Yumeng Wang, Xinheng He, Peiyu Xu, Sijie Huang, Qingning Yuan, Xinyue Zhang, Ling Wang, (unknown), Hong Chen, Zhen Li, (unknown), Sheng Wang, H. Eric Xu, Fei Xu	34
12	Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins 2023 ·Nature Chemical Biology ·Yue Wang, Weiyi Liu, Youwei Xu, Xinheng He, Qingning Yuan, Ping Luo, (unknown), (unknown), Xinyue Zhang, Xi Cheng, Yi Jiang, H. Eric Xu, Youwen Zhuang	36
13	GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors 2022 ·Molecular Cell ·Sijie Huang, Peiyu Xu, Dandan Shen, Ícaro A. Simon, Chunyou Mao, Yangxia Tan, Huibing Zhang, Kasper Harpsøe, Huadong Li, (unknown), Chongzhao You, Xuekui Yu, Yi Jiang, Yan Zhang, David E. Gloriam, H. Eric Xu	71
14	Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2 2021 ·Proceedings of the National Academy of Sciences ·(unknown), Xi Cheng, Lihua Zhao, Yuzhe Wang, Chenyu Ye, Xinyu Zou, Antao Dai, Zhaotong Cong, Jian Chen, Qingtong Zhou, Tian Xia, Hualiang Jiang, H. Eric Xu, Dehua Yang, Ming‐Wei Wang	25
15	Structural insights into the lipid and ligand regulation of serotonin receptors breakdown → 2021 ·Nature ·Peiyu Xu, Sijie Huang, Huibing Zhang, Chunyou Mao, X. Edward Zhou, Xi Cheng, Ícaro A. Simon, Dandan Shen, Hsin‐Yung Yen, Carol V. Robinson, Kasper Harpsøe, Bo Svensson, Jia Guo, Hualiang Jiang, David E. Gloriam, Karsten Melcher, Yi Jiang, Yan Zhang, H. Eric Xu	185
16	Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor 2021 ·Cell Research ·Youwen Zhuang, B. Krumm, Huibing Zhang, X. Edward Zhou, Yue Wang, Xi‐Ping Huang, Yongfeng Liu, Xi Cheng, Yi Jiang, Hualiang Jiang, Cheng Zhang, Wei Yi, Bryan L. Roth, Yan Zhang, H. Eric Xu	62
17	Structural Features for Functional Selectivity at Serotonin Receptors breakdown → 2013 ·Science ·Daniel Wacker, Chong Wang, Vsevolod Katritch, Gye Won Han, Xi‐Ping Huang, Eyal Vardy, John D. McCorvy, Yi Jiang, Meihua Chu, Fai Siu, Wei Liu, H. Eric Xu, Vadim Cherezov, Bryan L. Roth, Raymond C. Stevens	543
18	Structure of a PLS-class Pentatricopeptide Repeat Protein Provides Insights into Mechanism of RNA Recognition 2013 ·Journal of Biological Chemistry ·(unknown), Jiyuan Ke, Runze Chen, Xin Gu, Mingyue Tan, X. Edward Zhou, Yanyong Kang, Karsten Melcher, Jian‐Kang Zhu, H. Eric Xu	50
19	Structural Basis for Hormone Recognition by the Human CRFR2α G Protein-coupled Receptor 2010 ·Journal of Biological Chemistry ·Kuntal Pal, Kunchithapadam Swaminathan, H. Eric Xu, Augen A. Pioszak	63
20	Ohmefentanyl and Its Stereoisomers: Chemistry and Pharmacology 1997 ·Current Medicinal Chemistry ·George A. Brine, F. Ivy Carroll, (unknown), H. Eric Xu, (unknown)	10

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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