Huanchen Wang

5.0k total citations · 1 hit paper
83 papers, 3.9k citations indexed

About

Huanchen Wang is a scholar working on Molecular Biology, Cell Biology and Organic Chemistry. According to data from OpenAlex, Huanchen Wang has authored 83 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 75 papers in Molecular Biology, 24 papers in Cell Biology and 23 papers in Organic Chemistry. Recurrent topics in Huanchen Wang's work include Phosphodiesterase function and regulation (30 papers), Protein Kinase Regulation and GTPase Signaling (28 papers) and Cellular transport and secretion (20 papers). Huanchen Wang is often cited by papers focused on Phosphodiesterase function and regulation (30 papers), Protein Kinase Regulation and GTPase Signaling (28 papers) and Cellular transport and secretion (20 papers). Huanchen Wang collaborates with scholars based in United States, Germany and China. Huanchen Wang's co-authors include Hengming Ke, Stephen B. Shears, Howard Robinson, Qing Huai, Henning J. Jessen, Chunfang Gu, Yudong Liu, Jiwen Cai, Rachael P. Norris and Lisa M. Mehlmann and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Huanchen Wang

75 papers receiving 3.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

2011 659 citations Huanchen Wang, Hengming Ke et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Huanchen Wang United States	35	2.7k	680	623	591	557	83	3.9k
Consuelo Gajate Spain	43	3.7k 1.4×	1.0k 1.5×	251 0.4×	477 0.8×	567 1.0×	82	5.3k
Akihiro Ito Japan	32	5.2k 1.9×	762 1.1×	294 0.5×	825 1.4×	561 1.0×	130	6.6k
Jeffrey H. Grubb United States	43	3.0k 1.1×	961 1.4×	366 0.6×	637 1.1×	1.1k 2.0×	64	5.2k
Yongjun Dang China	33	3.3k 1.2×	496 0.7×	271 0.4×	645 1.1×	288 0.5×	101	5.2k
Jean‐Guy Delcros France	32	2.9k 1.1×	656 1.0×	524 0.8×	134 0.2×	507 0.9×	98	4.1k
Megan J. Robinson United States	18	3.2k 1.2×	522 0.8×	271 0.4×	314 0.5×	306 0.5×	20	4.4k
Young‐Ki Paik South Korea	40	3.1k 1.1×	291 0.4×	192 0.3×	251 0.4×	230 0.4×	159	5.2k
Margarita García‐Calvo United States	22	4.0k 1.5×	474 0.7×	193 0.3×	453 0.8×	296 0.5×	38	5.1k
William F. Matter United States	14	3.1k 1.1×	542 0.8×	186 0.3×	255 0.4×	222 0.4×	19	4.5k
Peter Hodder United States	36	2.5k 0.9×	596 0.9×	143 0.2×	295 0.5×	513 0.9×	135	4.0k

Countries citing papers authored by Huanchen Wang

Since Specialization

Citations

This map shows the geographic impact of Huanchen Wang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Huanchen Wang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Huanchen Wang more than expected).

Fields of papers citing papers by Huanchen Wang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Huanchen Wang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Huanchen Wang. The network helps show where Huanchen Wang may publish in the future.

Co-authorship network of co-authors of Huanchen Wang

This figure shows the co-authorship network connecting the top 25 collaborators of Huanchen Wang. A scholar is included among the top collaborators of Huanchen Wang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Huanchen Wang. Huanchen Wang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Huanchen, Stephen B. Shears, & Raymond D. Blind. (2025). Structural Rationalization of IPMK Inhibitor Potency. Journal of Medicinal Chemistry. 68(22). 24316–24325.

Wang, Huanchen, Ekaterina I. Goncharova, Henning J. Jessen, et al.. (2025). Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors. Journal of Biological Chemistry. 301(3). 108274–108274.

Hostachy, Sarah, Huanchen Wang, Guangning Zong, et al.. (2023). Fluorination Influences the Bioisostery of Myo‐Inositol Pyrophosphate Analogs. Chemistry - A European Journal. 29(67). e202302426–e202302426. 3 indexed citations

Wang, Huanchen, L. Perera, Nikolaus Jork, et al.. (2022). A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nature Communications. 13(1). 2231–2231. 11 indexed citations

Zhou, Yubai, Molee Chakraborty, Chunfang Gu, et al.. (2022). Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions. Journal of Medicinal Chemistry. 65(9). 6869–6887. 21 indexed citations

Wang, Zhenzhen, et al.. (2020). Rapid stimulation of cellular Pi uptake by the inositol pyrophosphate InsP₈induced by its photothermal release from lipid nanocarriers using a near infra-red light-emitting diode. Chemical Science. 11(37). 10265–10278. 6 indexed citations

Sahu, Soumyadip, Zhenzhen Wang, Xinfu Jiao, et al.. (2020). InsP₇is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics. Proceedings of the National Academy of Sciences. 117(32). 19245–19253. 24 indexed citations

An, Yi, Henning J. Jessen, Huanchen Wang, Stephen B. Shears, & Dmitri Kireev. (2019). Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine. Structure. 27(6). 1022–1028.e2. 9 indexed citations

Wang, Huanchen, Chunfang Gu, Ronda J. Rolfes, Henning J. Jessen, & Stephen B. Shears. (2018). Structural and biochemical characterization of Siw14: A protein-tyrosine phosphatase fold that metabolizes inositol pyrophosphates. Journal of Biological Chemistry. 293(18). 6905–6914. 24 indexed citations

10.

Stashko, Michael A., Huanchen Wang, Vikas Tyagi, et al.. (2018). Use of Protein Kinase–Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors. SLAS DISCOVERY. 23(9). 982–988. 18 indexed citations

11.

Wang, Huanchen, Stefan Kunz, Gong Chen, et al.. (2012). Biological and Structural Characterization of Trypanosoma cruzi Phosphodiesterase C and Implications for Design of Parasite Selective Inhibitors. Journal of Biological Chemistry. 287(15). 11788–11797. 20 indexed citations

12.

Shears, Stephen B., et al.. (2010). Diphosphoinositol polyphosphates: What are the mechanisms?. Advances in Enzyme Regulation. 51(1). 13–25. 24 indexed citations

13.

Norris, Rachael P., William J. Ratzan, Marina Freudzon, et al.. (2009). Cyclic GMP from the somatic cells of the mouse ovarian follicle regulates cyclic AMP and meiosis in the oocyte. Developmental Biology. 331(2). 419–419.

14.

Wang, Huanchen, Nuria E. Campillo, Sara Ballester, et al.. (2009). Synthesis, Structural Analysis, and Biological Evaluation of Thioxoquinazoline Derivatives as Phosphodiesterase 7 Inhibitors. ChemMedChem. 4(5). 866–876. 57 indexed citations

15.

Chen, Gong, Huanchen Wang, Howard Robinson, et al.. (2008). An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies. Biochemical Pharmacology. 75(9). 1717–1728. 25 indexed citations

16.

Hu, Xiaozhen, Huanchen Wang, Hengming Ke, & Brian Kuhlman. (2008). Computer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet Design. Structure. 16(12). 1799–1805. 36 indexed citations

17.

Hu, Xiaozhen, Huanchen Wang, Hengming Ke, & Brian Kuhlman. (2007). High-resolution design of a protein loop. Proceedings of the National Academy of Sciences. 104(45). 17668–17673. 97 indexed citations

18.

Huai, Qing, Yingjie Sun, Huanchen Wang, et al.. (2003). Crystal structure of DJ‐1/RS and implication on familial Parkinson's disease¹. FEBS Letters. 549(1-3). 171–175. 110 indexed citations

19.

Wang, Huanchen, et al.. (2003). A Correlation between TCR Vα Docking on MHC and CD8 Dependence. Immunity. 19(4). 595–606. 83 indexed citations

20.

Huai, Qing, et al.. (2003). Three-Dimensional Structures of PDE4D in Complex with Roliprams and Implication on Inhibitor Selectivity. Structure. 11(7). 865–873. 97 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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