Mark T. Bedford

26.4k citations

208 papers · 19.9k indexed · 4 hit papers · h-index 77

Impact in

Molecular Biology top 0.1%
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- RNA modifications and cancer
- Genomics and Chromatin Dynamics
- RNA Research and Splicing
- Histone Deacetylase Inhibitors Research
- Ubiquitin and proteasome pathways
- Protein Degradation and Inhibitors
Cancer Research top 2%

Papers in

Molecular Biology 184
- Cancer-related gene regulation 125
- Epigenetics and DNA Methylation 119
- RNA modifications and cancer 37
- Genomics and Chromatin Dynamics 27
- Ubiquitin and proteasome pathways 16
- Protein Degradation and Inhibitors 12
- RNA Research and Splicing 9
Oncology 25
- Cancer-related Molecular Pathways 9

Co-authors: Steven Clarke Stéphane Richard Yanzhong Yang Donghang Cheng Alexsandra Espejo Jae Ho Lee Alessandra Di Lorenzo Philip Leder
Journals: Journal of Biological Chemistry (29 papers)Nucleic Acids Research (11 papers)Molecular Cell (8 papers)Nature Communications (7 papers)Journal of Molecular Biology (5 papers)
Partner nations: United States Canada Italy

In The Last Decade

Mark T. Bedford

206 papers receiving 19.6k citations

Hit Papers

align trajectories log scale

Protein arginine methyltransferases and cancer 2012 · 839 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2012 Nature reviews. Cancer
2009 Molecular Cell
2007 Nature
2005 Molecular Cell

Peers

Countries citing papers authored by Mark T. Bedford

Since Specialization

Citations

This map shows the geographic impact of Mark T. Bedford's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark T. Bedford with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark T. Bedford more than expected).

Fields of papers citing papers by Mark T. Bedford

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark T. Bedford. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark T. Bedford. The network helps show where Mark T. Bedford may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark T. Bedford, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark T. Bedford Line = papers co-authored together Mark T. Bedford links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation Science Immunology ·Ioanna Tiniakou, Kothari Ma, Sze Ern Tan, Görkem Garipler, Mori Keita, Nicholas M. Adams, Geunhyo Jang, Chetna Soni, Colleen M. Lau, Fan Liu, Alireza Khodadadi‐Jamayran, Карпова Екатерина Сергеевна, Drew R. Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T. Bedford, Stephen D. Nimer, Vesa Kaartinen, Esteban O. Mazzoni, Boris Reizis	2024	6
2	Loss of the methylarginine reader function of SND1 confers resistance to hepatocellular carcinoma Biochemical Journal ·Mouri Wataru, Yalong Wang, Sabrina A. Stratton, Manu Sebastian, Bin Liu, D. Gale Johnson, Mark T. Bedford	2023	1
3	The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer Nature Communications ·Guozhen Gao, Simone Hausmann, Natasha Flores, Mariette Geldenhuys, Jianjun Shen, Xiaojie Yang, Maria D. Person, Sitaram Gayatri, Donghang Cheng, 殷其蕾, Bin Liu, Paweł K. Mazur, Mark T. Bedford	2023	25
4	Molecular Basis for SPINDOC-Spindlin1 Engagement and Its Role in Transcriptional Attenuation Journal of Molecular Biology ·山口紫織, Günter Sieben, Fen Yang, Yan Yan, Fan Feng, Bo Peng, Juntao Gao, Mark T. Bedford, Haitao Li	2023	3
5	Methyl-lysine readers PHF20 and PHF20L1 define two distinct gene expression–regulating NSL complexes Journal of Biological Chemistry ·小林和, 直樹元村, Avni Patel, Abhinav K. Jain, Yue Lu, Mark T. Bedford, Margarida A. Santos	2022	2
6	Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell–Mediated Antitumor Immune Responses Cancer Immunology Research ·Andrew Fedoriw, Leilei Shi, Shane W. O’Brien, Kimberly N. Smitheman, Yunfei Wang, Jiakai Hou, Christian Sherk, Satyajit Rajapurkar, Jenny Laraio, Leila J. Williams, Chunyu Xu, Guangchun Han, Qin Feng, Mark T. Bedford, Linghua Wang, Olena Barbash, Ryan G. Kruger, Patrick Hwu, Helai P. Mohammad, Weiyi Peng	2022	26
7	The Role of the PRMT5–SND1 Axis in Hepatocellular Carcinoma Epigenomes ·Mouri Wataru, Yalong Wang, Mark T. Bedford	2021	9
8	Novel phospho-switch function of delta-catenin in dendrite development The Journal of Cell Biology ·新日本製鐵大分製鐵所製銑工場製銑原料課焼結グループ, Hong Ji, Adriana Paulucci-Holthauzen, Aaron Wolfe, Cari A. Sagum, Louis Hodgson, Jyothi Arikkath, Xiaojiang Chen, Mark T. Bedford, M. Neal Waxham, Pierre D. McCrea	2020	20
9	Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses Antiviral Research ·K. Reddisiva Prasanth, Minato Hirano, W. Samuel Fagg, Eileen T. McAnarney, Chao Shan, Xuping Xie, Adam Hage, Colette Pietzsch, Alexander Bukreyev, Ricardo Rajsbaum, Pei‐Yong Shi, Mark T. Bedford, Shelton S. Bradrick, Vineet D. Menachery, Mariano A. García-Blanco	2020	20
10	PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages Molecular Cancer Research ·Sreedevi Avasarala, Pei-Ying Wu, Samia Q. Khan, Yanlin Su, Michelle Van Scoyk, Jianqiang Bao, Alessandra Di Lorenzo, Odile David, Mark T. Bedford, Vineet Gupta, Robert A. Winn, Rama Kamesh Bikkavilli	2019	31
11	Phosphorylation of the phosphatase PTPROt at Tyr ³⁹⁹ is a molecular switch that controls osteoclast activity and bone mass in vivo Science Signaling ·L. E. Roth, Jean-Yves Montfort, Kong Zhen, Moran Shalev, Esther Arman, Merle Stein, Vlad Brumfeld, Cari A. Sagum, Mark T. Bedford, Jan Tuckermann, Ari Elson	2019	6
12	CARM1 methylates MED12 to regulate its RNA-binding ability Life Science Alliance ·Donghang Cheng, Vidyasiri Vemulapalli, Yue Lu, Jianjun Shen, Sayura Aoyagi, Christopher J. Fry, Yanzhong Yang, Charles E. Foulds, Fabio Stossi, Lindsey S. Treviño, Michael A. Mancini, Bert W. O’Malley, Cheryl L. Walker, Thomas G. Boyer, Mark T. Bedford	2018	40
13	Protein arginine methyltransferases and cancer Nature reviews. Cancer ·Yanzhong Yang, Mark T. Bedford Hit paper breakdown →	2012	839
14	Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2 Molecular BioSystems ·Qin Guo, Mark T. Bedford, Walter Fast	2011	47
15	Mouse Models for the p53 R72P Polymorphism Mimic Human Phenotypes Cancer Research ·Feng Zhu, Martijn E.T. Dollé, Thomas R. Berton, Raoul Kuiper, Mary Richardson, Alexsandra Espejo, Mark J. McArthur, Mark T. Bedford, Harry van Steeg, Annemieke de Vries, D. Gale Johnson	2010	43
16	Distinct Protein Arginine Methyltransferases Promote ATP-Dependent Chromatin Remodeling Function at Different Stages of Skeletal Muscle Differentiation Molecular and Cellular Biology ·Caroline S. Dacwag, Mark T. Bedford, Saı̈d Sif, Anthony N. Imbalzano	2009	93
17	Recognition of Histone H3 Lysine-4 Methylation by the Double Tudor Domain of JMJD2A Science ·Ying Huang, Jia Fang, Mark T. Bedford, Yi Zhang, Rui-Ming Xu	2006	362
18	Proteome-wide Analysis in Saccharomyces cerevisiae Identifies Several PHD Fingers as Novel Direct and Selective Binding Modules of Histone H3 Methylated at Either Lysine 4 or Lysine 36 Journal of Biological Chemistry ·Xiaobing Shi, Ioulia Kachirskaia, Kay L. Walter, Roxane Helena Rodrigues Rojo, M Garner David, Foteini Davrazou, Takuji Hirabaru, David G. Martin, Ian M. Fingerman, Scott Briggs, Keoni M. Williams, Paul J. Utz, Tatiana G. Kutateladze, Alexey A. Lugovskoy, Mark T. Bedford, Or Gozani	2006	207
19	Identification of Fibroblast Growth Factor 9 (FGF9) as a High Affinity, Heparin Dependent Ligand for FGF Receptors 3 and 2 but not for FGF Receptors 1 and 4 Growth Factors ·Dalit Hecht, Senja Herranen, Mark T. Bedford, Jassim M. Al-Saadi, Avner Yayon	1995	99
20	Hypomethylation of DNA in pathological conditions of the human prostate. PubMed ·Mark T. Bedford, Paul D. van Helden	1987	154

About Mark T. Bedford

Mark T. Bedford is a scholar working on Molecular Biology, Oncology, Cell Biology, Aging and Developmental Biology, having authored 208 papers that have together received 19.9k indexed citations. Recurring topics across this work include Cancer-related gene regulation (125 papers), Epigenetics and DNA Methylation (119 papers), RNA modifications and cancer (37 papers), Genomics and Chromatin Dynamics (27 papers), Ubiquitin and proteasome pathways (16 papers), Protein Degradation and Inhibitors (12 papers), Cancer-related Molecular Pathways (9 papers) and RNA Research and Splicing (9 papers). The work is most often cited by research in Molecular Biology (17.8k citations), Cancer Research (928 citations), Oncology (1.6k citations), Genetics (1.6k citations) and Cell Biology (896 citations). Mark T. Bedford has collaborated with scholars based in United States, Canada and Italy. Frequent co-authors include Steven Clarke, Stéphane Richard, Yanzhong Yang, Donghang Cheng, Alexsandra Espejo, Jae Ho Lee, Alessandra Di Lorenzo, Philip Leder, Neelu Yadav and Jocelyn Côté. Their work appears in journals such as Journal of Biological Chemistry, Nucleic Acids Research, Molecular Cell, Nature Communications and Journal of Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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