Holger Rehmann

9.7k citations

75 papers · 7.2k indexed · 2 hit papers · h-index 39

Impact in

Geriatrics and Gerontology top 0.5%
- Sirtuins and Resveratrol in Medicine
Cell Biology top 0.5%
- Cellular Mechanics and Interactions
- Cellular transport and secretion

Papers in

Immunology and Allergy 10
- Cell Adhesion Molecules Research 10
Cell Biology 25
- Cellular transport and secretion 15
- Cellular Mechanics and Interactions 10

Co-authors: Johannes L. Bos Alfred Wittinghofer Johan de Rooij Frank Schwede Tishan Williams Alex B. Burgin Myung K. Kim Faiyaz Ahmad
Journals: Journal of Biological Chemistry (10 papers)Cell (4 papers)Cellular Signalling (4 papers)Scientific Reports (3 papers)PLoS Biology (3 papers)
Partner nations: Netherlands Germany United States

In The Last Decade

Holger Rehmann

75 papers receiving 7.1k citations

Hit Papers

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Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases 2012 · 1.1k citations

Peers

Countries citing papers authored by Holger Rehmann

Since Specialization

Citations

This map shows the geographic impact of Holger Rehmann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Holger Rehmann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Holger Rehmann more than expected).

Fields of papers citing papers by Holger Rehmann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Holger Rehmann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Holger Rehmann. The network helps show where Holger Rehmann may publish in the future.

Co-authors

The 25 scholars most cited alongside Holger Rehmann, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Holger Rehmann Line = papers co-authored together Holger Rehmann links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Isoleucine-to-valine substitutions support cellular physiology during isoleucine deprivation Nucleic Acids Research ·雅也守山, Imre F. Schene, Allessandra Biondi, Jenny Elliott, Marisa I. Mendes, Desirée E.C. Smith, Gajja S. Salomons, Carles Tarragó Bussom, Judith Jans, Maigan Ratangee, Tim A. Hoek, Matthew Cupelli, Holger Rehmann, Edward E. S. Nieuwenhuis, Harmjan R. Vos, Sabine A. Fuchs	2024	1
2	A second case of glutaminase hyperactivity: Expanding the phenotype with epilepsy JIMD Reports ·Rrafael Galvin, Petra J. W. Pouwels, Nicole I. Wolf, Holger Rehmann, Mirjam M. C. Wamelink, Quinten Waisfisz, Judith Jans, Hubertus C.M.T. Prinsen, Jiddeke M. van de Kamp, Peter M. van Hasselt	2023	3
3	FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer Cell Reports ·R. R. Allmaras, Nalan Liv, 方国云, Mark Opdam, Elaine Zózimo, Muhammad Shahid Maqbool, A.A. Blake, Rutger C.C. Hengeveld, Matthew Cupelli, Erik van Werkhoven, Harmjan R. Vos, Holger Rehmann, Boudewijn Burgering, Hendrika M. Oosterkamp, Susanne M.A. Lens, Judith Klumperman, Sabine C. Linn, Patrick W.B. Derksen	2022	7
4	Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling Nature Cell Biology ·Bas Ponsioen, S. Tayal, 久米進一郎, Rebeca Silva Bezerra, Ravian L. van Ineveld, Simone Kersten, Andrea Bertotti, Francesco Sassi, François Sipieter, Benjamin Cappe, Sander Mertens, Ingrid Verlaan-Klink, Sylvia F. Boj, I Martin, Holger Rehmann, Peter Vandenabeele, Franck B. Riquet, Livio Trusolino, Johannes L. Bos, Hugo J.G. Snippert	2021	94
5	Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy JAMA Neurology ·Rrafael Galvin, LI Bian-jiang, Oliver Maier, Holger Rehmann, Maarten H. Lequin, Jan-Ulrich Schlump, Bernhard Schmitt, Arnd Krause, Hubertus C.M.T. Prinsen, M. Kemal Demirkırkan, Ralph Fingerhut, Johannes R. Lemke, Fried Zwartkruis, Roderick H.J. Houwen, Judith Jans, Nanda M. Verhoeven‐Duif, Peter M. van Hasselt, Rami Abou Jamra	2018	34
6	Efficient Intracellular Delivery of Native Proteins Cell ·Diego S. D’Astolfo, Romina J. Pagliero, Шахризода Адхам қизи Саидова, Wouter R. Karthaus, Hans Clevers, Vikram Prasad, Robert Jan Lebbink, Holger Rehmann, Niels Geijsen	2015	284
7	Rap1 and Rap2 Antagonistically Control Endothelial Barrier Resistance PLoS ONE ·Willem‐Jan Pannekoek, Jelena R. Linnemann, G. J. Ashworth, Johannes L. Bos, Holger Rehmann	2013	37
8	The Small GTPase RALA Controls c-Jun N-terminal Kinase-mediated FOXO Activation by Regulation of a JIP1 Scaffold Complex Journal of Biological Chemistry ·Maaike C.W. van den Berg, 北村祥子, Alida M.M. Smits, Miranda van Triest, Tobias B. Dansen, Marieke Visscher, Paulien E. Polderman, Marjolein J. Vliem, Holger Rehmann, Boudewijn Burgering	2013	30
9	Selectivity of CDC25 Homology Domain-Containing Guanine Nucleotide Exchange Factors Journal of Molecular Biology ·Milica Popović, Dohwon Jung, Holger Rehmann	2013	17
10	Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling The Journal of Cell Biology ·Stephan Huveneers, Joppe Oldenburg, Emma Spanjaard, Rani Septiani Rahmawati, Ilya Grigoriev, Anna Akhmanova, Holger Rehmann, Johan de Rooij	2012	373
11	Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases BMC Proceedings ·Sung-Jun Park, Faiyaz Ahmad, Andrew Philp, Keith Baar, Tishan Williams, Hai‐Bin Luo, Hengming Ke, Holger Rehmann, Ronald Taussig, Alexandra L. Brown, Myung K. Kim, Michael A. Beaven, Alex B. Burgin, Vincent C. Manganiello, Jay H. Chung	2012	11
12	Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases Cell ·Sung Jun Park, Faiyaz Ahmad, Andrew Philp, Keith Baar, Tishan Williams, Hai‐Bin Luo, Hengming Ke, Holger Rehmann, Ronald Taussig, Alexandra L. Brown, Myung K. Kim, Michael A. Beaven, Alex B. Burgin, Vincent C. Manganiello, Jay H. Chung Hit paper breakdown →	2012	1105
13	Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control Cellular Signalling ·Willem‐Jan Pannekoek, Kiran Ghafoor, Franciszek K. Gtowka, Stephan Huveneers, Jelena R. Linnemann, Emma Spanjaard, G. J. Ashworth, Anne Jan van der Meer, Fried Zwartkruis, Holger Rehmann, Johan de Rooij, Johannes L. Bos	2011	60
14	Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·大島光, Toshiya Fuke, Milica Popović, 秦光潤, Julie Vallières, Tamara Vučenović, Holger Rehmann, Ruth Herbst	2011	13
15	Biochemical characterisation of TCTP questions its function as a guanine nucleotide exchange factor for Rheb FEBS Letters ·Holger Rehmann, Marc Bruning, Christiane Meyer, Melanie Schwarten, Katja Köhler, Hugo Stocker, Raphael Stoll, Fried Zwartkruis, Alfred Wittinghofer	2008	70
16	Characterization of the GbpD-activated Rap1 Pathway Regulating Adhesion and Cell Polarity in Dictyostelium discoideum Journal of Biological Chemistry ·Arjan Kortholt, Holger Rehmann, Ming-Tsung Wu, Leonard Bosgraaf, Ineke Keizer‐Gunnink, Gerald Weeks, Alfred Wittinghofer, Peter J.M. Van Haastert	2006	48
17	Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state Nature ·Holger Rehmann, Rocío A. de la Fuente González, Puck Knipscheer, Alfred Wittinghofer, Johannes L. Bos	2006	168
18	Ligand-mediated Activation of the cAMP-responsive Guanine Nucleotide Exchange Factor Epac Journal of Biological Chemistry ·Holger Rehmann, Frank Schwede, Stein Ove Døskeland, Alfred Wittinghofer, Johannes L. Bos	2003	133
19	A new phospholipase-C–calcium signalling pathway mediated by cyclic AMP and a Rap GTPase Nature Cell Biology ·Martina Schmidt, Sandrine Evellin, Paschal A. Oude Weernink, F. vom Dorp, Holger Rehmann, Jon W. Lomasney, Karl H. Jakobs	2001	287
20	Mechanism of Regulation of the Epac Family of cAMP-dependent RapGEFs Journal of Biological Chemistry ·Johan de Rooij, Holger Rehmann, Miranda van Triest, Robbert H. Cool, Alfred Wittinghofer, Johannes L. Bos	2000	324

About Holger Rehmann

Holger Rehmann is a scholar working on Immunology and Allergy, Cell Biology, Physiology, Molecular Biology and Aging, having authored 75 papers that have together received 7.2k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (25 papers), Cellular transport and secretion (15 papers), Phosphodiesterase function and regulation (14 papers), Signaling Pathways in Disease (12 papers), Cellular Mechanics and Interactions (10 papers), Receptor Mechanisms and Signaling (10 papers), Cell Adhesion Molecules Research (10 papers) and Ion channel regulation and function (6 papers). The work is most often cited by research in Geriatrics and Gerontology (589 citations), Cell Biology (1.7k citations), Immunology and Allergy (468 citations), Aging (134 citations) and Molecular Biology (5.1k citations). Holger Rehmann has collaborated with scholars based in Netherlands, Germany and United States. Frequent co-authors include Johannes L. Bos, Alfred Wittinghofer, Johan de Rooij, Frank Schwede, Tishan Williams, Alex B. Burgin, Myung K. Kim, Faiyaz Ahmad, Andrew Philp and Hai‐Bin Luo. Their work appears in journals such as Journal of Biological Chemistry, Cell, Cellular Signalling, Scientific Reports and PLoS Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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