William J. Hoekstra

2.7k total citations · 1 hit paper
70 papers, 2.2k citations indexed

About

William J. Hoekstra is a scholar working on Infectious Diseases, Organic Chemistry and Molecular Biology. According to data from OpenAlex, William J. Hoekstra has authored 70 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Infectious Diseases, 18 papers in Organic Chemistry and 17 papers in Molecular Biology. Recurrent topics in William J. Hoekstra's work include Antifungal resistance and susceptibility (18 papers), Fungal Infections and Studies (12 papers) and Chemical Synthesis and Analysis (10 papers). William J. Hoekstra is often cited by papers focused on Antifungal resistance and susceptibility (18 papers), Fungal Infections and Studies (12 papers) and Chemical Synthesis and Analysis (10 papers). William J. Hoekstra collaborates with scholars based in United States, United Kingdom and Uganda. William J. Hoekstra's co-authors include Robert J. Schotzinger, Edward P. Garvey, Bruce E. Maryanoff, Christopher M. Yates, Barry G. Shearer, Patricia Andrade‐Gordon, Z. Wawrzak, Tatiana Y. Hargrove, Galina I. Lepesheva and Aidong Qi and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Oncology.

In The Last Decade

William J. Hoekstra

69 papers receiving 2.1k citations

Hit Papers

Structural analyses of Ca... 2017 2026 2020 2023 2017 100 200 300
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis
    2017 317 citations Tatiana Y. Hargrove, Laura Friggeri et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
William J. Hoekstra United States 27 728 701 609 568 310 70 2.2k
Lars Petter Jordheim France 27 524 0.7× 597 0.9× 1.7k 2.8× 370 0.7× 166 0.5× 109 3.1k
Marco Radi Italy 29 1.4k 1.9× 349 0.5× 981 1.6× 123 0.2× 137 0.4× 97 2.5k
Philip E.J. Sanderson United States 20 652 0.9× 301 0.4× 609 1.0× 148 0.3× 123 0.4× 37 1.7k
Michael G. Natchus United States 29 744 1.0× 1.0k 1.4× 879 1.4× 585 1.0× 84 0.3× 69 2.9k
Cristina Tintori Italy 27 861 1.2× 300 0.4× 724 1.2× 152 0.3× 115 0.4× 52 1.8k
Daniel A. Harki United States 28 422 0.6× 371 0.5× 1.6k 2.6× 219 0.4× 153 0.5× 77 2.6k
Pierre Raboisson Belgium 24 555 0.8× 497 0.7× 634 1.0× 534 0.9× 62 0.2× 60 1.8k
Ginger E. Dutschman United States 32 555 0.8× 1.3k 1.9× 1.4k 2.3× 1.0k 1.8× 40 0.1× 88 3.1k
Shridhar Bhat United States 21 403 0.6× 333 0.5× 1.5k 2.5× 345 0.6× 44 0.1× 37 2.6k
Michele Connelly United States 30 452 0.6× 661 0.9× 1.6k 2.7× 486 0.9× 48 0.2× 66 3.1k

Countries citing papers authored by William J. Hoekstra

Since Specialization
Citations

This map shows the geographic impact of William J. Hoekstra's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William J. Hoekstra with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William J. Hoekstra more than expected).

Fields of papers citing papers by William J. Hoekstra

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William J. Hoekstra. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William J. Hoekstra. The network helps show where William J. Hoekstra may publish in the future.

Co-authorship network of co-authors of William J. Hoekstra

This figure shows the co-authorship network connecting the top 25 collaborators of William J. Hoekstra. A scholar is included among the top collaborators of William J. Hoekstra based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William J. Hoekstra. William J. Hoekstra is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Pitt, Bertram, Deepak L. Bhatt, J. David Becherer, et al.. (2020). Abstract P233: Inhibition Of Aldosterone Synthesis In Non-human Primates By PB6440, The Novel Highly Selective And Potent CYP11B2 Inhibitor. Hypertension. 76(Suppl_1). 1 indexed citations
2.
Hargrove, Tatiana Y., Laura Friggeri, Z. Wawrzak, et al.. (2017). Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis. Journal of Biological Chemistry. 292(16). 6728–6743. 317 indexed citations breakdown →
3.
Shubitz, Lisa F., et al.. (2017). Efficacy of the Investigational Antifungal VT-1161 in Treating Naturally Occurring Coccidioidomycosis in Dogs. Antimicrobial Agents and Chemotherapy. 61(5). 16 indexed citations
4.
Yates, Christopher M., Edward P. Garvey, Sammy R. Shaver, Robert J. Schotzinger, & William J. Hoekstra. (2017). Design and optimization of highly-selective, broad spectrum fungal CYP51 inhibitors. Bioorganic & Medicinal Chemistry Letters. 27(15). 3243–3248. 71 indexed citations
5.
Shubitz, Lisa F., Hien T. Trinh, John N. Galgiani, et al.. (2015). Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models. Antimicrobial Agents and Chemotherapy. 59(12). 7249–7254. 41 indexed citations
6.
Trump, Ryan P., Barry G. Shearer, Millard H. Lambert, et al.. (2007). Co-crystal structure guided array synthesis of PPARγ inverse agonists. Bioorganic & Medicinal Chemistry Letters. 17(14). 3916–3920. 15 indexed citations
7.
Wiethe, Robert W., et al.. (2006). Array synthesis of progesterone receptor antagonists: 3-Aryl-1,2-diazepines. Bioorganic & Medicinal Chemistry Letters. 16(14). 3777–3779. 14 indexed citations
8.
Jones, David G., Xi Liang, Eugene L. Stewart, et al.. (2005). Discovery of non-steroidal mifepristone mimetics: Pyrazoline-based PR antagonists. Bioorganic & Medicinal Chemistry Letters. 15(13). 3203–3206. 26 indexed citations
9.
Kinney, William A., Li Liu, Shyamali Ghosh, et al.. (2004). Piperidine-containing β-arylpropionic acids as potent antagonists of αvβ3/αvβ5 integrins. Bioorganic & Medicinal Chemistry Letters. 14(20). 5227–5232. 17 indexed citations
10.
Dyatkin, Alexey B., William J. Hoekstra, William A. Kinney, et al.. (2003). Aza-bicyclic amino acid sulfonamides as α4β1/α4β7 integrin antagonists. Bioorganic & Medicinal Chemistry Letters. 14(3). 591–596. 7 indexed citations
11.
Dyatkin, Alexey B., William J. Hoekstra, Dennis J. Hlasta, et al.. (2002). Bridged bicyclic vasopressin receptor antagonists with V2-Selective or dual V1a/V2 activity. Bioorganic & Medicinal Chemistry Letters. 12(21). 3081–3084. 10 indexed citations
12.
Damiano, Bruce P., John A. Mitchell, Edward C. Giardino, et al.. (2001). Antiplatelet and Antithrombotic Activity of RWJ-53308, A Novel Orally Active Glycoprotein IIb/IIIa Antagonist. Thrombosis Research. 104(2). 113–126. 26 indexed citations
13.
Hecker, Leonard R., William J. Hoekstra, Cynthia A. Maryanoff, et al.. (2000). An Expedient Method for Resolution of 3-Amino-3-(3‘-pyridyl)propionic Acid and Related Compounds. Organic Process Research & Development. 5(1). 23–27. 10 indexed citations
14.
Elliott, John T., William J. Hoekstra, Bruce E. Maryanoff, & Glenn D. Prestwich. (1999). Photoactivatable peptides based on BMS-197525: A potent antagonist of the human thrombin receptor (PAR-1). Bioorganic & Medicinal Chemistry Letters. 9(2). 279–284. 12 indexed citations
15.
Hoekstra, William J., David F. McComsey, Patricia Andrade‐Gordon, et al.. (1998). Thrombin receptor (PAR-1) antagonists. Heterocycle-based peptidomimetics of the SFLLR agonist motif. Bioorganic & Medicinal Chemistry Letters. 8(13). 1649–1654. 29 indexed citations
16.
Mayo, Kevin H., Mary Pat Beavers, Annette Eckardt, et al.. (1996). Integrin Receptor GPIIb/IIIa Bound State Conformation of the Fibrinogen γ-Chain C-Terminal Peptide 400−411:  NMR and Transfer NOE Studies. Biochemistry. 35(14). 4434–4444. 16 indexed citations
17.
Hoekstra, William J., Mary Pat Beavers, Patricia Andrade‐Gordon, et al.. (1995). Design and Evaluation of Nonpeptide Fibrinogen .gamma. Chain-Based GPIIB/IIIA Antagonists. Journal of Medicinal Chemistry. 38(10). 1582–1592. 27 indexed citations
18.
Liu, Paul S., et al.. (1990). Synthesis of potent anti-HIV agents: Esters of castanospermine. Tetrahedron Letters. 31(20). 2829–2832. 30 indexed citations
19.
Dunams, Tambra M., et al.. (1988). Molecular aggregation and its applicability to synthesis. The Diels-Alder reaction. Tetrahedron Letters. 29(31). 3745–3748. 23 indexed citations
20.
Goldsmith, David J., et al.. (1985). Preparation and reactivity of α-phenylselenenyl ethers. Tetrahedron. 41(21). 4873–4880. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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