G. Bruce Wisely

12.2k total citations · 7 hit papers
37 papers, 10.1k citations indexed

About

G. Bruce Wisely is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, G. Bruce Wisely has authored 37 papers receiving a total of 10.1k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 11 papers in Genetics and 9 papers in Oncology. Recurrent topics in G. Bruce Wisely's work include Estrogen and related hormone effects (10 papers), Peroxisome Proliferator-Activated Receptors (9 papers) and Drug Transport and Resistance Mechanisms (8 papers). G. Bruce Wisely is often cited by papers focused on Estrogen and related hormone effects (10 papers), Peroxisome Proliferator-Activated Receptors (9 papers) and Drug Transport and Resistance Mechanisms (8 papers). G. Bruce Wisely collaborates with scholars based in United States, Netherlands and Australia. G. Bruce Wisely's co-authors include Timothy M. Willson, Steven A. Kliewer, Stacey A. Jones, Millard H. Lambert, Linda B. Moore, Peter J. Brown, Jürgen M. Lehmann, Robert T. Nolte, Christopher K. Glass and Riki Kurokawa and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

G. Bruce Wisely

37 papers receiving 9.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

1997 1.8k citations Steven A. Kliewer, Stacey A. Jones et al. profile →
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

1998 1.6k citations Robert T. Nolte, G. Bruce Wisely et al. Nature profile →
Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

1999 938 citations H. Eric Xu, Millard H. Lambert et al. Molecular Cell profile →
Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ

1999 774 citations Stacey A. Jones, G. Bruce Wisely et al. profile →
St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

2000 706 citations Linda B. Moore, Stacey A. Jones et al. profile →
The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity

2001 609 citations G. Bruce Wisely, Linda B. Moore et al. Science profile →
Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

2007 572 citations Lei Yin, Nan Wu et al. Science profile →

Peers

Countries citing papers authored by G. Bruce Wisely

Since Specialization

Citations

This map shows the geographic impact of G. Bruce Wisely's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by G. Bruce Wisely with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites G. Bruce Wisely more than expected).

Fields of papers citing papers by G. Bruce Wisely

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by G. Bruce Wisely. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by G. Bruce Wisely. The network helps show where G. Bruce Wisely may publish in the future.

Co-authorship network of co-authors of G. Bruce Wisely

This figure shows the co-authorship network connecting the top 25 collaborators of G. Bruce Wisely. A scholar is included among the top collaborators of G. Bruce Wisely based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with G. Bruce Wisely. G. Bruce Wisely is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene 2011 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	28
2	Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene 2010 ·Bioorganic & Medicinal Chemistry Letters ·Jonathan Y. Bass, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Wendy Y. Mills, Frank Navas, Derek J. Parks, Terrence L. Smalley, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	53
3	Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064 2009 ·Bioorganic & Medicinal Chemistry Letters ·Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Derek J. Parks, Dan Todd, Shawn P. Williams, G. Bruce Wisely	45
4	FXR agonist activity of conformationally constrained analogs of GW 4064 2009 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	56
5	Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064 2008 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Stacey A. Jones, István Káldor, Yaping Liu, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Frank Navas, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely	118
6	Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways breakdown → 2007 ·Science ·Lei Yin, Nan Wu, Joshua C. Curtin, Mohammed Qatanani, (unknown), Robert A. Reid, (unknown), Derek J. Parks, Kenneth H. Pearce, G. Bruce Wisely, Mitchell A. Lazar	572
7	Crystallization of protein–ligand complexes 2006 ·Acta Crystallographica Section D Biological Crystallography ·Anne M. Hassell, Gang An, Randy K. Bledsoe, Jane M. Bynum, H. Luke Carter, Su-Jun Deng, Robert T. Gampe, (unknown), Kevin P. Madauss, Robert T. Nolte, Warren J. Rocque, Liping Wang, Kurt Weaver, Shawn P. Williams, G. Bruce Wisely, Robert X. Xu, Lisa M. Shewchuk	120
8	Structural Disorder in the Complex of Human Pregnane X Receptor and the Macrolide Antibiotic Rifampicin 2005 ·Molecular Endocrinology ·Jill Chrencik, Jillian Orans, Linda B. Moore, Yu Xue, Li Peng, Jon L. Collins, G. Bruce Wisely, Millard H. Lambert, Steven A. Kliewer, Matthew R. Redinbo	160
9	Helix 1/8 Interactions Influence the Activity of Nuclear Receptor Ligand-Binding Domains 2003 ·Molecular Endocrinology ·Jason A. Holt, Thomas G. Consler, Shawn P. Williams, (unknown), Lisa M. Leesnitzer, G. Bruce Wisely, Andrew N. Billin	6
10	Use of in vitro pregnane X receptor assays to assess CYP3A4 induction potential of drug candidates 2002 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Stacey A. Jones, Linda B. Moore, G. Bruce Wisely, Steven A. Kliewer	10
11	Production and Characterization of an Estrogen Receptor β Subtype-Specific Mouse Monoclonal Antibody 2000 ·Hybridoma ·Jui‐Lan Su, David D. McKee, Byron Ellis, Sue H. Kadwell, G. Bruce Wisely, Linda B. Moore, (unknown), Thomas A. Kost, Suzanne A.W. Fuqua, John T. Moore	7
12	Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix 2000 ·Genes & Development ·Robert T. Gampe, Valerie G. Montana, Millard H. Lambert, G. Bruce Wisely, Michael V. Milburn, H. Eric Xu	111
13	Production of monoclonal antibodies using recombinant baculovirus displaying gp64–fusion proteins 2000 ·Journal of Immunological Methods ·(unknown), Jui‐Lan Su, (unknown), G. Bruce Wisely, Randy K. Bledsoe, J. Patrick Condreay, Deborah A. Winegar, Jeff Hutchins, Thomas A. Kost	50
14	Use of a PPAR Gamma-Specific Monoclonal Antibody to Demonstrate Thiazolidinediones Induce PPAR Gamma Receptor Expression In Vitro 1999 ·Hybridoma ·Jui‐Lan Su, Deborah A. Winegar, G. Bruce Wisely, Carlie Sigel, Emily A. Hull-Ryde	9
15	Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors breakdown → 1999 ·Molecular Cell ·H. Eric Xu, Millard H. Lambert, Valerie G. Montana, Derek J. Parks, Steven G. Blanchard, Peter J. Brown, Daniel D. Sternbach, Jürgen M. Lehmann, G. Bruce Wisely, Timothy M. Willson, Steven A. Kliewer, Michael V. Milburn	938
16	Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators 1998 ·Nature ·Stefan Westin, Riki Kurokawa, Robert T. Nolte, G. Bruce Wisely, Eileen M. McInerney, David W. Rose, Michael V. Milburn, Michael G. Rosenfeld, Christopher K. Glass	284
17	Detailed Characterization of a Purified Type 4 Phosphodiesterase, HSPDE4B2B: Differentiation of High- and Low-Affinity (R)-Rolipram Binding 1997 ·Protein Expression and Purification ·Warren J. Rocque, William D. Holmes, Indravadan R. Patel, R. W. Dougherty, Olivia Ittoop, Laurie K. Overton, Christine R. Hoffman, G. Bruce Wisely, Derril H. Willard, Michael Luther	37
18	NF- k appa B regulates IL-1 beta transcription through a consensus NF- k appa B binding site and a nonconsensus CRE-like site. 1994 ·The Journal of Immunology ·John Cogswell, (unknown), G. Bruce Wisely, William C. Clay, Lisa M. Leesnitzer, J P Ways, John G. Gray	324
19	Nucleotide sequence of the BALB/c mouse β-globin complex 1989 ·Journal of Molecular Biology ·W. Ronald Shehee, Daniel D. Loeb, Nils B. Adey, Frank H. Burton, N. Carol Casavant, Pascale Colé, Christopher Davies, Royal A. McGraw, Steven A. Schichman, (unknown), Charles F. Voliva, (unknown), G. Bruce Wisely, Marshall H. Edgell, Clyde A. Hutchison	82
20	Molecular and genetic organization of the suppressor of sable and minute (1) 1B region in Drosophila melanogaster. 1989 ·Genetics ·Robert A. Voelker, Shu‐Mei Huang, G. Bruce Wisely, Joan F. Sterling, (unknown), (unknown)	18

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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